• Title/Summary/Keyword: power of discrimination

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Genetic Polymorphisms of the Human Thyroid Peroxidase Gene Using Amplified Fragment Length Polymorphism: Application to the Determination of Paternity in a Korean Population. (한국인에서 중합효소연쇄반응을 이용한 Human Thyroid Peroxidase 유전자의 유전적 다형성에 관한 연구)

  • Kyung Ok Lee;Taek-Kyu Park;Moon-Ju Oh;Eun-Ha Kim;Young-Suk Park;Yoon Jung Kim;Kyu Pum Lee
    • Biomedical Science Letters
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    • v.1 no.1
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    • pp.9-18
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    • 1995
  • Genetic polymorphisms due to variation in the number of tandem repeats of DNA sequences(VNTRs) provides a useful means for discrimination between individuals. Allele and genotype frequencies of the highly polymorphic Human Thyroid Peroxidase(TPO) gene were determined in Korean population samples by using PCR followed by polyacrylamide gel electrophoresis, a procedure called the amplified fragment length polymorphism(Amp-FLP) technique. In 123 unrelated Korean individuals 10 different alleles and 29 genotypes were observed. The TPO gene demonstrated a heterozygosity of 0.707 and the power of exclusion(POE) was 0.945. The probability of having the same DNA band within two unrelated individuals was 14.6$\times10^{-2}$. The distribution of observed genotypes conformed to Hardy-Weinberg equilibrium($x^2$=4.48, 0.05

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Establishment of Genetic Characteristics and Individual Identification System Using Microsatellite Loci in Jeju Native Horse (초위성체 DNA를 이용한 제주마 집단의 품종특성 및 개체식별 체계설정)

  • Cho, Byung-Wook;Jung, Ji-Hye;Kim, Sang-Wook;Kim, Heui-Soo;Lee, Hak-Kyo;Cho, Gil-Jae;Song, Ki-Duk
    • Journal of Life Science
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    • v.17 no.10
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    • pp.1441-1446
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    • 2007
  • This study was conducted to establish the individual identification system and to estimate the genetic characteristic of Jeju native horse (JNH) using 13 microsatellite markers located on different horse autosomes. The markers were genotyped on 191 animals from five horse breeds including Jeju native horse (JNH). In total, 138 alleles were detected from the genotypes of 13 microsatellite markers. The average heterozygosities ranged from 0.317 to 0.902 and the polymorphic information content (PIC) ranged from 0.498 to 0.799 in JNH. We found that there were significant differences in allele frequencies in JNH when compared with other horse breeds. In ATH4 marker, there were specific allele frequence pattern that some of allele only found in JNH, Mongolian horse (MONG) and Jeju racing horse (JRH). The calculated cumulative power of discrimination (CPD) was 99.9% when nine microsatellite loci were used for analysis in the individual identification system. Also, the matching probability that two unrelated animals would show the same genotypes, was estimated to be $0.60{\times}10^{-10}$. Therefore, in the nine markers used in this study can be used for individual identification in the Jeju native horse population.

The Sociocultural Codes for Interpreting Racism in Puerto Rico (푸에르토리코의 인종주의를 읽는 세 가지 사회문화적 코드)

  • Lee, Euna
    • Cross-Cultural Studies
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    • v.44
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    • pp.7-28
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    • 2016
  • This study examines the sociocultural background of negritude by delving into Caseríos, Reggaeton, and $Trigue{\tilde{n}}os$, which are interrelated with the racism deeply embedded in Puerto Rican society. These terms have also been discussed in relation to the ideological discourse of racial democracy, which has caused Puerto Rican people to be blind to silenced inequality and hegemonic racial policies. Caseríos, housing projects for the poor urban class, are targeted by the state - sponsored project 'Mano Dura'. Due to the policing, control and surveillance of this anticrime project, Caseríos became perceived even more as residential communities of violence, poverty, and insecurity generally connected to the stigmatization of blackness. Reggaeton emerged as a mega hit genre of transnational Puerto Rican music in the 2000s, which in turn, drew attention to both the afrodiaspora in New York and the urban musical power in the Island. This musical genre serves to highlight the meaningfulness of black heritage in the national cultural identity of Puerto Rico. $Trigue{\tilde{n}}idad$ has recently become a common racial cultural term that embraces a broader racial paradigm of mestizaje. This term can function as an alternative concept of blackness, but it has not yet been transformed into enough cultural politics to resist ongoing racial democracy. The three terms intrinsically address both the uprooted racism and potential methods of challenging it. This paper argues the necessity of stronger and more responsive cultural politics to defy the pervasiveness and invisibility of racial discrimination in Puerto Rico.

A study on possibility of soft target terrorism by ISIS in South Korea (자국내 IS테러단체에 의한 소프트타깃 테러발생 가능성에 대한 연구)

  • Oh, Sei-Youen;Yun, Gyeong-Hui
    • Korean Security Journal
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    • no.47
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    • pp.85-117
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    • 2016
  • These days, ISIS terrorists have been expanding not only to european countries, but also to asian countries so South Korea is no longer safe from terrorists' attacks. Especially, 'soft target terrorism' makes many people maximizing fear of terrorism because it is caused by small groups - those who are armed with small arms and light weapons - and they are able to carry out hit and run attacks on civilian targets. It poses even more dangerous to kill massively. That is why November 2015 Paris attacks and January 2016 Jakarta attacks killed and injured many people because of 'soft target terrorism.' Therefore, the South Korea has also recognized the seriousness of terrorism by ISIS. The study has shown the precautionary measures about 'soft target terrorism' and how to defend against 'soft target terrorism' by looking through overseas examples. It is for the possibilities of 'soft terrorism' in South Korea because of the expansion of ISIS. As a result, 'soft target terrorism', caused by ISIS, could happen in South Korea. The counterplan is as in the following. First of all, 'soft target terrorism', which is collaborated with ISIS and domestic terrorists, could be caused by negative awareness of foreign residents and xenophobia so the public should change stereotypes about the foreign residents and there should be legislation about racial discrimination enacted by parliament and the government must practice the law. Second, the Korean anti-terrorism laws should be modified to minimize violations of human rights, related to the Korean citizens' personal information, and to stop the concentration of power into the hands of one law enforcement. Third, the government has to develop and to initiate the refuge&evacuation simulation, which prepares for 'soft target terrorism' and minimizes the damages if terrorists attack hot spots like central commercial areas or event halls.

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Characterization of a Korean Traditional Porcine Breed Using Microsatellite Markers and the Establishment of an Individual Identification System (Microsatellite Marker를 이용한 한국재래돼지 집단의 품종특성 및 원산지 추적을 위한 개체식별체계 설정)

  • Kim, M.J.;Li, G.H.;Oh, J.D.;Cho, K.H.;Jeon, G.J.;Choi, B.H.;Lee, J.H.;Hong, Y.S.;Kong, H.S.;Lee, H.K.
    • Food Science of Animal Resources
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    • v.27 no.2
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    • pp.150-156
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    • 2007
  • This study was conducted to analyze the genetic characteristics of Korean Native Pigs(KNP), and to establish an individual identification system comprising many microsatellite markers located on different pig autosomes. Genotype data from 13 microsatellites typed in 446 animals was used to determine the validation of a method of individual identification in 4 KNP. A total of 112 alleles of the 13 microsatellites were detected and average heterozygosities(polymorphic information content) ranged from 0.286(0.423) to 0.686(0.796) in this study. Comparing the pattern of allele frequency among the KNP, Yorkshire, Landrace and Duroc breeds, there was specific differentiation between populations at multi-allelic loci. The cumulative power of discrimination(CPD) was 99.999% by including 10 microsatellite loci for the individual identification system. The probability that two different individuals incidentally have same genotype was estimated to be $0.36{\times}10^{-9}$. The system employing these 10 markers therefore proved to be applicable to the individual identification of KNP.

Effectiveness of multi-mode surface wave inversion in shallow engineering site investigations (토목관련 천부층 조사에서 다중 모드 표면파 역산의 효과)

  • Feng Shaokong;Sugiyama Takeshi;Yamanaka Hiroaki
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.26-33
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    • 2005
  • Inversion of multi-mode surface-wave phase velocity for shallow engineering site investigation has received much attention in recent years. A sensitivity analysis and inversion of both synthetic and field data demonstrates the greater effectiveness of this method over employing the fundamental mode alone. Perturbation of thickness and shear-wave velocity parameters in multi-modal Rayleigh wave phase velocities revealed that the sensitivities of higher modes: (a) concentrate in different frequency bands, and (b) are greater than the fundamental mode for deeper parameters. These observations suggest that multi-mode phase velocity inversion can provide better parameter discrimination and imaging of deep structure, especially with a velocity reversal, than can inversion of fundamental mode data alone. An inversion of the theoretical phase velocities in a model with a low velocity layer at 20 m depth can only image the soft layer when the first higher mode is incorporated. This is especially important when the lowest measurable frequency is only 6 Hz. Field tests were conducted at sites surveyed by borehole and PS logging. At the first site, an array microtremor survey, often used for deep geological surveying in Japan, was used to survey the soil down to 35 m depth. At the second site, linear multichannel spreads with a sledgehammer source were recorded, for an investigation down to 12 m depth. The f-k power spectrum method was applied for dispersion analysis, and velocities up to the second higher mode were observed in each test. The multi-mode inversion results agree well with PS logs, but models estimated from the fundamental mode alone show f large underestimation of the depth to shallow soft layers below artificial fill.

Construction of a DNA Profile Database for Commercial Cucumber (Cucumis sativus L.) Cultivars Using Microsatellite Marker (Microsatellite 마커를 이용한 오이 유통품종 DNA Profile Data Base 구축)

  • Kwon, Yong-Sham;Choi, Keun-Jin
    • Horticultural Science & Technology
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    • v.31 no.3
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    • pp.344-351
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    • 2013
  • Microsatellite is one of the most suitable marker for cultivar identification as it has great discrimination power for cultivars with narrow genetic variation. The polymorphism level between 358 microsatellite primer pairs and 11 commercial cucumber cultivars was investigated. Thirty-one primer pairs showed high polymorphism within cucumber cultivars with different fruit types. These markers were applied for the constructing DNA profile data base of 110 commercial cucumber cultivars through multiplex PCR and fluorescence based automatic detection system. A total of 139 polymorphic amplified fragments were obtained by using 31 microsatellite markers. The average of PIC value was 0.610 ranging from 0.253 to 0.873. One hundred and thirty nine microsatellite loci were used to calculate Jaccard's distance coefficients for UPGMA cluster analysis. A clustering group of varieties, based on the results of microsatellite analysis, were categorized into plant shape and fruit type. Almost the cultivars were discriminated by marker genotypes. This information may be useful to compare through genetic relationship analysis between existing variety and candidate varieties in distinctive tests and protection of plant breeders' intellectual property rights through variety identification.

A Survey of Korean Youths' Gender Equality consciousness and Its Relationship with General Value (한국청소년의 성평등의식 실태와 일반적 가치와의 관계에 관한 연구)

  • Park, Soo-Mi
    • Korea journal of population studies
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    • v.31 no.3
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    • pp.85-106
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    • 2008
  • This study explores Korean youths' gender equality consciousness in an attempt to search for a way to increase youth's gender equality consciousness. First, this study carries out a survey of youths' gender equality consciousness based on questionnaires collected from a nationwide sample. Second, this study attempts to identify key points needed to evaluate youths' gender equality consciousness in terms of youths' general values. The data used for this survey is from the survey on youths' values conducted by Korean Institute for Health and Social Affairs in 2006 with a sample of 11,240 students from 132 schools nationwide. As a result, youths in 2006 had higher gender equality consciousness than that of previous years(2002). Especially, the support for the fair share of domestic work in the house by youths was significantly increased than the past. However, the survey of youths' values showed clear gender gaps in general attitudes of youths including gender equality consciousness. Female students not only had higher gender equality consciousness than male students but also had higher levels of 'universal value' which would allow one to become sensitive to discrimination and 'self development and achievement value'. In contrast, male students scored high on 'power-oriented value' related to discriminatory attitudes. Therefore, the study recommends focusing on alleviating the gender gaps through school education and other various media education.

A Comparative Analysis of increased along with the age presbyopic additions in city and island villages (도시와 섬마을 노안의 연령에 따른 근용 가입도의 비교 관찰)

  • Kim, In-Suk;Ryu, Geun-Chang
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.61-65
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    • 2002
  • This study examines how the average presbyopic additions and eye refraction state of old ages in city may be different to that island. There were 677 of the old who were 50 or over 90 in the sample. The visual acuity test was done by objective and subjective methods and used for near-chart program. The far-point refraction state and power of the additions lens results were as follows ; 1. Of far-point refraction state in city peoples; male: emmetropia 10%, myopia 17%, hyperopia 19%, mixed astigmatism 38%, etc. 16% female : emmetropia 20%, myopia 20%, hyperopia 20%, mixed astigmatism 27%, etc. 13% 2. Of far-point refraction state in island villages ; male : emmetropia 13%, myopia 17%, hyperopia 22%, mixed astigmatism 40%, etc. 8% female : emmetropia 7%, myopia 13%, hyperopia 26%, mixed astigmatism 44%, etc. 10% 3. Average presbyopic additions states has been presented no discrimination ; male: 50 to 60 : +1.25 or +1.50D, 61 to 65 : +1.75 or + 2.00D, 66 to 70 : +2.25 or +2.50D 71 to 75 : +2.75 or +3.00D, 76 to 80 : +3.25 or +3.50D, over81 : +3.75D female : 50 to 60 : +1.25 or + 1.50D, 61 to 65 : +1.75 or + 2.00D, 66 to 70 : +2.25 or +2.50D 71 to 75 : +2.25 or + 2.50D, 76 to 80 : +2.75 or +3.00D, over81 : +2.75 or +3.00D 4. Under the condition of wearing lens, the average working time was 1 or 2 hour but some people used over 5 hours. 5. Generally, it has been investigated the old ages peoples has ocular diseases and cataract was the most common.

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Analysis of High-growth SMEs using Technology Appraisal Items for Investment: Focusing on Sales and Operating Profit (기술투자 평가항목을 활용한 고성장 중소기업 판별: 매출액과 영업이익을 중심으로)

  • Lee, Jun-won
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.19 no.4
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    • pp.115-125
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    • 2024
  • This study defined the appraisal items of technology appraisal for investment as innovation characteristics and derived the determining factors for predicting high-growth companies. Through this, we presented a direction for improving the technology appraisal model for investment. High-growth companies were classified into high-growth companies in sales, high-growth companies in operating profit, and high-growth companies in both sales and operating profit. At this time, the concept of a gazelle company was applied and defined as a company with an average growth rate of 20% or more over three years after the appraisal year. As for the analysis results, in terms of technicality (appraisal items), it was significant in predicting high-growth companies in sales and high-growth companies in sales and operating profit. Therefore, it will be possible to increase the discrimination power of predictions by strengthening the technicality (appraisal items). On the other hand, the business feasibility (appraisal items) was significant in predicting high-growth companies in sales and high-growth companies in sales and operating profit, but in a negative direction. This is due to the composition and criteria of the business feasibility (appraisal items), and it was concluded that changes to the composition and criteria for the relevant items are necessary for future model improvement.

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