• 안보군사학연구
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• 통권5호
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• pp.241-280
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• 2007

This study examines the relationship of the industry-specific factors that effect innovation of manufacturing technology and the market share within the defense industry. Since the establishment of the basic defense industry framework in 1973, there were numerous interactions of the industry-specific factors of the defense industry structure with the technological innovation and market organization of the defense industry. During last three decades, the domestic defense industry has achieved the considerable level but the framework of the basic system has not developed much in areas of the military science and the defense manufacturing technology. Industry-specific factors were formed in the process and appeared in a variety of behavioral characteristics as subsystems. Currently, there IS a growing trend where the management of defense industry is gradually deteriorating due to limitation of the domestic industry-specific factor (e.g. defense technologies, amount of demand, etc.). If there is a prominent imbalance of the industry-specific factors. it can trigger the potential problem of conflict, lack of cooperation and control, slowing the growth of the manufacturing technology thereby diminishing the market and deteriorating the defense supply/demand relationship. In a research conducted by Joe S. Bain, Bain analyzed the relationship of the traditional industrial organization where industry-specific factor(S) not only impacts the conductor(C). And, conductor(C) influences the shaping of the performance(P) of relationship of the traditional industrial organization. Consequently, the researcher has identified the demand monopoly, barriers to entry, and market competition with comparison of defense industry issues. These defense issues were three industry-specific factors identified, which are 1) The demand monopoly and The entry barriers to new market competition, 2) the industrial technical factor to a production technical competitiveness and a market sharing competitiveness, 3) the probability factor to revolution for military affairs(RMA) and a R&D production. According to baseline with these factors, the following research model is established from the special companies group(Group A), the systematization companies group(Group B), and the general companies group(Group 0. The hypothesis is that if there are more industry-specific factors, then there will be more relationships of defense industry relation statutes. This research is an empirical study on the relationship that the industry specific factors effects the innovation of manufacturing technology and the shaping of the market in the defense industry. Moreover, the existing models to evaluate the industry specific factors of the defense industry IS much to be desired with the controlled statistical analysis of the result. It is vital to study on current situation with suggesting alternative strategy to the efficient strategy. The descriptive analysis approach analysis is conducted with SPSSWIN to conduct reliability test, factor analysis, correlation analysis, cross-tabulation analysis, one-way ANOVA, and multiple regression analysis. However, there were some limitations of the survey such as the rigidity of concept about the technical factors and various market management factors. The wishes is that the decision-maker could be utilized these defence industrial factors to formulate efficient defence policy and strategy in the future.

• 한국중재학회지:중재연구
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• 제18권1호
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• pp.3-30
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• 2008

This paper is to research the current status of ADR in Korea, the qualifications of mediator (or conciliator) and arbitrator, the ADR education program of major foreign arbitration-related institutions and the efficient management device of ADR education program for the activation of the ADR system. In 2007, arbitration applications received at the Korean Commercial Arbitration Board numbered 320 and the amount involved those cases was US$ 216 millions. Mediation applications received at the KCAB numbered 552 and the amount involved those cases US$ 29millions. As of December 2007, the total numbers of arbitrators on the KCAB Panel of Arbitrators was 978. There are no provisions for the qualification of arbitrator in the UNCITRAL Model Law on International Commercial Arbitration and Arbitration Act of Korea. The KCAB has the consolidation regulation of the Panel of Arbitrator of which purpose is to regulate the criteria and procedure regarding the drawing up and maintenance of the panel of arbitrators. The UK Chartered Institute of Arbitrators has the criteria and qualifications for membership of which three grades are associate, member and fellow. The American Arbitration Association has the qualification criteria for admittance to the AAA National Roster of Arbitrators and Mediators. The Japan Association of Arbitrators has the official authorization regulation for membership of which three grades are special associate, ordinary associate and fellow. The UK Chartered Institute of Arbitrators has the ADR education programs which are composed of the mediation courses and arbitration courses. The American arbitrators Association has the ADR education programs which are composed of in-person training and online training. The Japan Association of Arbitrators has the ADR education programs which are composed of the cultivation courses of conciliator and the practical training courses of arbitrator. The efficient management devices of ADR education program are as follows: the execution of official authorization system of arbitrator, the establishment of specialized division for training and official authorization, the establishment of ADR regular training courses, the publication of ADR training texts and obtaining of instructors, and the consolidation of regulations related to the official authorization of arbitrator and ADR training. In conclusion, for the activation of ADR system, the KCAB and Korean Association of Arbitrators should make further effort to provide the ADR regular education and training programs for potential and practicing conciliators and arbitrators.

• 디지털융복합연구
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• 제12권5호
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• pp.159-169
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• 2014

공공부문 정보화 프로젝트에 도입하려는 PMO 제도는 전자정부 정보화 프로젝트의 철저한 사업관리를 통해 위험을 방지하고 품질향상을 통해 글로벌 소프트웨어 강국으로서 세계 제일의 스마트 전자정부를 선도하려는 목적을 가지고 있다. 이에 본 연구는 공공부문 PMO 제도를 시행하기에 앞서 이해관계자를 대상으로 PMO 도입 행위의도에 영향을 미치는 주요 요인에 대한 연구를 통하여 공공부문의 PMO 운영 모델을 제시하고자 한다. 연구 수행은 공공부문의 PMO 도입이 프로젝트를 통합적으로 관리하는 새로운 관리 기술로 판단하여 통합된 신정보기술수용 이론인 UTAUT 모형을 기반으로 공공부문 PMO 도입 행위의도에 관한 연구를 수행하였다. 연구결과 프로젝트관리 성과기대에 대한 PMO 도입 행위의도에 대해서는 긍정적인 영향을 미치는 것으로 나타났으며, PMO 도입으로 부가적 성과를 얻고자 하는 노력에 대한 기대는 PMO 도입 행위의도에 대해 영향을 미치지 않는 것으로 나타났다. PMO 조직활동이 PMO 도입의 촉진조건으로서 PMO 도입 행위의도에 대해 긍정적 영향을 미치는 것으로 나타났다. 본 연구에서 이해관계자 그룹 간 노력에 대한 기대와 촉진조건이 PMO 도입 행위의도 조절효과가 나타날 것이라는 가설 아래 검증을 수행한 결과 각 그룹간 조절효과가 유의하지 않은 것으로 나타나 공공부문의 PMO 도입 행위의도에 대해서는 이해관계자 그룹간 공통된 인식을 하고 있음을 확인할 수 있었다.

• 한국환경생태학회지
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• 제27권5호
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• pp.614-624
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• 2013

본 연구는 경주국립공원 전체 지구를 대상으로 토양침식에 대해 RUSLE 기법을 활용하여 잠재적 토양유실량과 침식위험도를 파악함으로써 토양생태계의 지속적인 보전과 더불어 재해방지 계획 수립을 위한 기초 자료 제공에 그 목적이 있다. 연평균 토양침식량 분석 결과, 전체 지구의 평균 토양침식량은 5.7ton/ha/yr로 나타났으며, 지구별로 남산 지구가 7.6ton/ha/yr로 가장 높았고 서악 지구가 2.1ton/ha/yr로 가장 낮았다. 토양침식위험등급 지역은 1% 미만으로 분석되었으며, 구미산 지구와 화랑 지구는 심각한 지역이 없었다. 그러나 남산 지구는 심각한 지역이 다른 지구에 비해 높게 나타났으며, 금오봉 일대에 집중되어 있었다. 따라서 금오봉 일대를 보호하기 위해서는 적절한 복원 및 관리방안이 수립되어야 할 것이다. 경주국립공원의 토지피복형태는 대부분 산림지역으로 나타났으며, 평균 토양침식량이 3.7ton/ha/yr로 양호한 수준인 것으로 확인되었다. 지형에 따른 토양침식량 분석 결과, 깊은 계곡이 단위면적 당 7.3ton/ha/yr로 나타났으며, 다음이 평탄곡지로 6.1ton/ha/yr로 분석되었다. 평탄지와 산정능선은 토양침식이 적게 발생되는 것으로 예측되었다. 향후, 국내 국립공원의 토양유실량을 분석한다면, 전체 국립공원의 토양생태계를 보전 및 복원할 수 있는 계획 수립에 도움이 될 것으로 기대된다.

• IMMUNE NETWORK
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• 제11권1호
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• pp.79-94
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• 2011

Background: Dendritic cell (DC)-based vaccines are currently being evaluated as a novel strategy for tumor vaccination and immunotherapy. However, inducing long-term regression in established tumor-implanted mice is difficult. Here, we show that deoxypohophyllotoxin (DPT) induces maturation and activation of bone marrow-derived DCs via Toll-like receptor (TLR) 4 activation of MAPK and NF-${\kappa}B$. Methods: The phenotypic and functional maturation of DPT-treated DCs was assessed by flow cytometric analysis and cytokine production, respectively. DPT-treated DCs was also used for mixed leukocyte reaction to evaluate T cell-priming capacity and for tumor regression against melanoma. Results: DPT promoted the activation of $CD8^+$ T cells and the Th1 immune response by inducing IL-12 production in DCs. In a B16F10 melanoma-implanted mouse model, we demonstrated that DPT-treated DCs (DPT-DCs) enhance immune priming and regression of an established tumor in vivo. Furthermore, migration of DPT-DCs to the draining lymph nodes was induced via CCR7 upregulation. Mice that received DPT-DCs displayed enhanced antitumor therapeutic efficacy, which was associated with increased IFN-${\gamma}$ production and induction of cytotoxic T lymphocyte activity. Conclusion: These findings strongly suggest that the adjuvant effect of DPT in DC vaccination is associated with the polarization of T effector cells toward a Th1 phenotype and provides a potential therapeutic antitumor immunity.

• 한국환경과학회지
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• 제25권10호
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• pp.1349-1368
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• 2016

Concentrations of fine particulate matter ($PM_{2.5}$) and several of its particle constituents measured outside homes in Houston, Texas, and Los Angeles, California, were characterized using multiple regression analysis with proximity to point and mobile sources and meteorological factors as the independent variables. $PM_{2.5}$ mass and the concentrations of organic carbon (OC), elemental carbon (EC), benzo-[a]-pyrene (BaP), perylene (Per), benzo-[g,h,i]-perylene (BghiP), and coronene (Cor) were examined. Negative associations of wind speed with concentrations demonstrated the effect of dilution by high wind speed. Atmospheric stability increase was associated with concentration increase. Petrochemical source proximity was included in the EC model in Houston. Area source proximity was not selected for any of the $PM_{2.5}$ constituents' regression models. When the median values of the meteorological factors were used and the proximity to sources varied, the air concentrations calculated using the models for the eleven $PM_{2.5}$ constituents outside the homes closest to influential highways were 1.5-15.8 fold higher than those outside homes furthest from the highway emission sources. When the median distance to the sources was used in the models, the concentrations of the $PM_{2.5}$ constituents varied 2 to 82 fold, as the meteorological conditions varied over the observed range. We found different relationships between the two urban areas, illustrating the unique nature of urban sources and suggesting that localized sources need to be evaluated carefully to understand their potential contributions to $PM_{2.5}$ mass and its particle constituents concentrations near residences, which influence baseline indoor air concentrations and personal exposures. The results of this study could assist in the appropriate design of monitoring networks for community-level sampling and help improve the accuracy of exposure models linking emission sources with estimated pollutant concentrations at the residential level.

• 전기화학회지
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• 제1권1호
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• pp.40-44
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• 1998

pH변화를 정밀하게 측정하기 위하여 빠른 응답특성과 높은 감도를 갖는 전기화학적 전위차를 이용한 LAPS(Light-Addressable Potentiometric Sensor) 소자 및 시스템을 제작하여 그 기초 특성을 조사하였다. 먼저 pH 변화에 따른 LAPS의 정전기적 인 변화특성 및 소자의 변수를 LAPS 등가회로 모델을 이용한 모의실험을 통해 검증하고 이러한 모의 실험을 바탕으로 하여 LAPS 소자 및 시스템을 제작하였다. 제작된 LAPS 시스템은 pH 2-11 사이에서 56 mV/pH의 선형적인 감도를 보였다. 구성된 LAPS 시스템의 다양한 응용성을 도모하기 위한 시도로서 먼저, 일반적인 urea 센서가 가지는 긴 응답시간의 단점을 극복하기 위해 nitrocellulose membrane 에 urease가 고정화된 막을 LAPS에 부착하여 측정한 결과 urease 농도 $50{\mu}g/ml,500{\mu}g/ml$에 대하여 각각 0.29mV/sec, 0.816 mV/sec의 매우빠른 응답특성을 얻을 수 있었다. 또한 환경적 측면에서 중요한 우라닐 이온의 감지를 위하여 우라늄 인식 매체를 LAPS의 감지부에 부착하고 수용액 속에 녹아 있는 우라늄 이온을 측정한 결과 $10^{-11}\~10^{-4}M$의 넓은 농도 범위에서 25mV/decade 감도를 보였다

• 대한본초학회지
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• 제32권1호
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• pp.25-31
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• 2017

Objectives : Mori Radicis Cortex (MRC), the root epidermis of Morus alba L., has been traditionally used to treat lung-related diseases in Korean Medicine. The common of MRC is Mulberry bark Morus bark, and it's pharmaceutical properties and taste are known as sweet and cold, and it promotes urination and reduce edema by reducing heat from the lungs and soothe asthma. In the present study, anti-apoptotic mechanism of MRC in middle cerebral artery occlusion (MCAO) model in mice. Methods : Two-hundred grams of MRC was extracted with methanol at room temperature for 5 days, and this was repeated one time. After filtration, the methanol was removed using vacuum evaporator, then stored at $-20^{\circ}C$ until use. C57BL/6 male mice were housed in an environment with controlled humidity, temperature, and light cycle. In order to determine beneficial effects of MRC on ischemia induced brain damage, infarct volume, neurological deficit scores, activities of several apoptosis-related proteins such as caspase-8, -9, Bcl-xL in MCAO-induced brains of mice were analyzed. Mice in MRC-treated groups were orally administered 30, 100, or 300 mg/kg of body weight for three consecutive days before commencing the MCAO procedure. Results : Pre-treatment of MRC significantly reduced infarct volume in MCAO subjected mice applied with 300 mg/kg of MRC methanol extract, and MRC effectively inhibited Bcl-xL reduction and caspase-9 activation caused by MCAO-induced brain damage. Conclusions : MRC showed neuro-protective effects by regulating apoptosis-related protein signals, and it can be a potential candidate for the therapy of ischemia-induced brain damage.

• Tuberculosis and Respiratory Diseases
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• 제77권2호
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• pp.65-72
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• 2014

Background: It is valuable to find the potential activity of regulating the excessive mucin secretion by the compounds derived from various medicinal plants. We investigated whether aqueous extract of the root bark of Morus alba L. (AMA), kuwanon E, kuwanon G, mulberrofuran G, and morusin significantly affect the secretion and production of airway mucin using in vivo and in vitro experimental models. Methods: Effect of AMA was examined on hypersecretion of airway mucin in sulfur dioxide-induced acute bronchitis in rats. Confluent NCI-H292 cells were pretreated with ethanolic extract, kuwanon E, kuwanon G, mulberrofuran G, or morusin for 30 minutes and then stimulated with phorbol 12-myristate 13-acetate (PMA) for 24 hours. The MUC5AC mucin secretion and production were measured by enzyme-linked immunosorbent assay. Results: AMA stimulated the secretion of airway mucin in sulfur dioxide-induced bronchitis rat model; aqueous extract, ethanolic extract, kuwanon E, kuwanon G, mulberrofuran G and morusin inhibited the production of MUC5AC mucin induced by PMA from NCI-H292 cells, respectively. Conclusion: These results suggest that extract of the root bark and the natural products derived from Morus alba L. can regulate the secretion and production of airway mucin and, at least in part, explains the folk use of extract of Morus alba L. as mucoregulators in diverse inflammatory pulmonary diseases.

• 한국지반공학회논문집
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• 제21권8호
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• pp.95-105
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• 2005

토목섬유로 보강된 성토사면에 대한 사면안정해석은 보강재의 효과를 고려하여 수정된 한계평형해석법을 사용하는 것이 일반적이나, 대부분의 경우 보강재에 의하여 활동면상에 증가된 전단저항력만을 고려함으로써 전체 활동토체의 평형조건의 만족여부는 확실치 않다. 일반적으로 사면안정해석은 활동면상의 법선응력의 분포를 구하는 것으로 귀결 되므로, 본 연구에서는 활동면상에 작용하는 법선응력의 분포를 수평방향의 거리 $\chi$에 대한 2차함수로 가정하여 보강재의 효과를 고려하면서 힘과 모멘트의 평형조건을 모두 만족하는 새로운 사면안정해석법을 제안하였다. 제안된 사면 안정해석법은 잘 알려진 보강 및 무보강 사면에 대한 사면안정해석 사례와 보강토 옹벽 및 보강사면에 대한 모형실험 결과에 대한 해석을 통하여 그 타당성을 검토하였다. 그 결과 본 연구에서 제안한 방법은 보강 및 무보강사면에 대하여 타당한 사면활동에 대한 안전율을 제공해주는 것으로 나타났다.