• 핵의학기술
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• 제20권1호
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• pp.37-41
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• 2016

정도관리(Quality Control)는 오차를 최소한으로 하여 검사의 신뢰도를 증진 시키는 것을 목적으로 하고 있으며 이러한 정도관리 활동을 통해 환자의 진단과 치료방침에 영향을 주는 핵의학 혈액 검사의 신뢰도가 확보되고 있다. 이에 연구자들은 신뢰도 향상의 추가적인 기법으로 건강검진 수검자를 대상으로 시행한 핵의학 혈액검사의 모집단 분포를 이용한 통계적 품질관리의 유용성을 평가해 보고자 한다. 2014년 1월부터 2014년 12월까지 서울아산병원 건강증진센터를 이용한 건강검진 수검자 41,341명을 대상으로 핵의학 혈액 검사 12종목에 대해 통계 분석을 시행 하였다. 통계분석은 핵의학 혈액 검사 12종목에 대한 결과 보고 치를 참고치 이내, 참고치 이상, 참고치 이하의 세 가지 그룹의 월간 백분율로 구분하여 모집단 분포의 평균값과 표준편차, 그리고 표준편차 지수(Standard Deviation Index: SDI)를 산출 하였고 그 결과 모집단 분포의 표준편차는 모든 그룹에서 대부분 ${\pm}2SD$ 이내의 결과를 보였다. 건강검진 수검자에 대한 핵의학 혈액검사 12종목(AFP, CEA, CA19-9, CA125, PSA, TSH, FT4, Anti-Tg-Ab, Anti-TPO-Ab, Calcitonin, 25-OH-VitD3, Insulin)의 모집단 분포를 분석한 결과 월간 백분율의 표준편차 지수(SDI)가 ${\pm}2.0$ 이상인 경우는, 1월과 3월 Insulin검사에서 각각 2.3, 2.4, 5월 Anti-Tg-Ab검사에서 2.2, 그리고 9월 CA19-9에서 2.2의 결과를 보였다. 이는 검사 Kit 시약의 이상 (동위원소 시약의 최대 결합률 저하), 검사반응 시간의 저하가 원인 이었다. 연구대상이 되는 전체의 속성을 포함하고 모집단 분포의 특성을 이용한 통계적 품질관리는 검사실에서 시행하고 있는 내부정도관리 프로그램을 보완하는 역할을 할 수 있으리라 생각된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.719-722
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• 2016

Background: Cholangiocarcinoma (CCA) is a serious health problem in Thailand, particularly in northeastern and northern regions, but epidemiological studies are scarce and the spatial distribution of CCA remains to be determined. A database for the population at risk is required for monitoring, surveillance and organization of home health care. This study aim was to geo-visually display the distribution of CCA in northeast Thailand, using a geographic information system and Google Earth. Materials and Methods: A cross-sectional survey was carried out in 9 sub-districts and 133 villages in Chum Phuang district, Nakhon Ratchasima province during June and October 2015. Data on demography, and the population at risk for CCA were combined with the points of villages, sub-district boundaries, district boundaries, and points of hospitals in districts, then fed into a geographical information system. After the conversion, all of the data were imported into Google Earth for geo-visualization. Results: A total of 11,960 from 83,096 population were included in this study. Females and male were 52.5%, and 47.8%, the age group 41-50 years old 33.3%. Individual risk for CCA was identifed and classified by using the Korat CCA verbal screening test as low (92.8%), followed by high risk (6.74%), and no (0.49%), respectively. Gender ($X^2$-test=1143.63, p-value= 0.001), age group ($X^2$-test==211.36, p-value=0.0001), and sub-district ($X^2$-test=1471.858, p-value=0.0001) were significantly associated with CCA risk. Spatial distribution of the population at risk for CCA in Chum Phuang district was viewed with Google Earth. Geo-visual display followed Layer 1: District, Layer 2: Sub-district, Layer 3: Number of low risk in village, Layer 4: Number of high risk in village, and Layer 5: Hospital in Chum Phuang District and their related catchment areas. Conclusions: We present the first risk geo-visual display of CCA in this rural community, which is important for spatial targeting of control efforts. Risk appears to be strongly associated with gender, age group, and sub-district. Therefor, spatial distribution is suitable for the use in the further monitoring, surveillance, and home health care for CCA.

• 대한지역사회영양학회지
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• 제28권5호
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• pp.414-422
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• 2023

Objectives: This study evaluated usual dietary intakes of total fat and fatty acids among the Korean population based on the revised Dietary Reference Intakes for Koreans 2020 (2020 KDRIs). Methods: This study utilized data from the eighth Korea National Health and Nutrition Examination Survey (KNHANES 2019-2021). We included 18,895 individuals aged 1 year and above whose 1-day 24-hour dietary recall data were available. To calculate the external variability using the National Cancer Institute 1-day method, data from the U.S. NHANES 2017-March 2020 Pre-pandemic dataset were employed. The total fat and fatty acid intake were evaluated based on the Acceptable Macronutrient Distribution Ranges (AMDRs) and Adequate intake (AI) of 2020 KDRIs for each sex and age groups. Results: Approximately 86% of the Korean population obtained an adequate amount of energy from total fat consumption (within the AMDRs), indicating an appropriate level of intake. However, the percentage of individuals consuming saturated fatty acids below the AMDR was low, with only 12% among those under 19 years of age and 52% aged 19 years and older. On a positive note, approximately 70% of the population showed adequate consumption of essential fatty acids, exceeding the AI. Nevertheless, monitoring the intake ratio of omega 3 (n-3) to omega 6 (n-6) fatty acids is essential to ensure an optimum balance. Conclusions: This study explored the possibility of estimating the distribution of nutrient intake in a population by applying the external variability ratio. Therefore, if future KNHANES conduct multiple 24-hour recalls every few years-similar to the U.S. NHANES-even for a subset of participants, this may aid in the accurate assessment of the nutritional status of the population.

• Spatial Information Research
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• 제22권3호
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• pp.35-46
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• 2014

공간 분석 연구를 위해 사용되는 대부분의 통계 자료는 행정구역 단위로 구축되어 있어 보다 세밀한 분석을 위해서는 에어리얼 인터폴레이션이 필요하다. 본 연구의 주된 목적은 전체 인구가 아니라 하위 인구집단에 초점을 두어 에어리얼 인터폴레이션을 실행하기 위한 방법들을 비교 검토하는 것이다. 서울의 2010년 센서스 데이터를 이용해 행정동 단위의 고령인구와 일인가구를 사례로 고해상도의 공간 단위로 인터폴레이션 한 후 경험 데이터와 비교함으로써 서로 다른 방법들의 적용 가능성을 평가하였다. 그 결과 전체 집단과 하위 집단 간에, 그리고 하위 집단 간에도 우수한 실행방법이 다소 간의 차이를 나타내었다. 총인구와 총가구는 건물용도 및 GWR(geographically weighted regression)을 이용한 방법이, 고령인구는 건물용도 및 OLS 회귀분석을 이용한 방법이, 일인가구는 토지용도 및 OLS를 이용한 방법이 가장 좋은 결과를 보였다. 이상의 결과를 토대로 대표적인 사회적 약자인 서울의 일인고령가구에 대한 분포를 고해상도의 공간 단위로 재현하였으며, 이러한 접근은 관련 도시 정책의 실행에 큰 기여를 할 것으로 기대된다.

• Journal of Microbiology and Biotechnology
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• 제17권10호
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• pp.1645-1654
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• 2007

The total methylotrophic population associated with rice plants from different cultivars was enumerated at three different stages: vegetative, flowering, and harvesting. The bacterial population in the leaf, rhizosphere soil, endophytic in the stem and roots, and epiphytic in the florets and grains were determined from four rice cultivars, Il-mi, Nam-pyeoung, O-dae, and Dong-jin, sampled from three different field sites. The methylotrophic bacteria isolated on AMS media containing 0.5% methanol as the sole carbon source uniformly showed three distinct morphologies, which were recorded as separate groups and their distribution among the various samples was determined using the ecophysiological index. The growth stage at the time of sampling had a more significant effect on the methylotrophic population and their distribution than the field site or cultivar. A similar effect was also observed for the PPFMs, where their population in different plant parts increased from V10 to R4 and then decreased towards stage R9. A canonical discriminant analysis of the PPFM population from different parts of rice showed clear variations among the cultivars, sampled sites, and growth stages, although the variations were more prominent among the growth stages.

• Asian-Australasian Journal of Animal Sciences
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• 제24권8호
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• pp.1048-1052
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• 2011

The Chinese Holstein cattle breed, an introduced breed in China, has been crossbred with native cattle breeds. We hypothesised that the Chinese Holstein local population in Beijing share haplotypes with native Asian cattle breeds, the result of a sudden population expansion in the recent past. We also hypothesised that crossbreeding and population expansion left traces that shaped the genetic makeup of the breed. Evaluation of this was performed by mitochondrial DNA (mtDNA) sequence analysis of Chinese Holstein cattle from Beijing (n = 41) and a comparison of them with the published mtDNA sequences (n = 293) of 14 Asian breeds with an emphasis on Chinese native cattle breeds. Three shared common haplotypes between Chinese Holstein cattle and native Asian cattle were found. Moreover, a high level of haplotype diversity in Chinese Holstein cattle (h = 0.9557) and low nucleotide diversity (${\pi}$ = 0.0052) was found, indicating a past population bottleneck followed by rapid population growth. These findings are supported by the significantly negative deviation of Tajima's D (-1.82085), the star-like pattern of dominant haplotypes and the pairwise mismatch distribution analysis, which showed a unimodal pattern.

• 천문학회지
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• 제38권3호
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• pp.345-355
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• 2005

We present a photometric study of the star cluster system in the merging galaxy NGC 1487, based on the BI photometry obtained from the F450W and F814W images in the HST /WFPC2 archive data. We have found about 560 star cluster candidates in NGC 1487, using the morphological parameters of the objects. We have investigated several photometric characteristics of the clusters: color-magnitude diagrams (CMDs), color distribution, spatial distribution, age, size and luminosity function. The CMD of the bright clusters with 18.5 < B < 24 mag in NGC 1487 shows three major populations of clusters: a blue cluster population with $(B-I){\le}0.45$, an intermediate-color cluster population with $0.45<(B-I){\le}1.55$, and a red cluster population with (B - I) > 1.55. The intermediate-color population is the most dominant among the three populations. The brightest clusters in the blue and intermediate- color populations are as bright as $B{\approx}18mag$ ($M_B{\approx}-12mag$), which are three magnitudes brighter than those in the red population. The blue and intermediate-color clusters are strongly concentrated on the bright condensations, while the red clusters are relatively more scattered over the galaxy. The CMD of these clusters is found to be remarkably similar to that of the clusters in the famous interacting system M51. From this we suggest that the intermediate-color clusters were, probably, formed during the merging process which occurred about 500 Myrs ago.

• 한국컴퓨터정보학회논문지
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• 제21권7호
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• pp.85-92
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• 2016

The law of large numbers, central limit theorem, and connection among binomial distribution, normal distribution, and statistical estimation require dynamics of continuous visualization for students' better understanding of the concepts. During this visualization process, the differences and similarities between statistical probability and mathematical probability that students should observe need to be provided with the intermediate steps in the converging process. We propose a visualization method that can integrate intermediate processes and results through Excel. In this process, students' experiences with dynamic visualization help them to perceive that the results are continuously changed and extracted from multiple situations. Considering modeling as a key process, we developed a classroom exercise using Excel to estimate the population mean and standard deviation by using a sample mean computed from a collection of data out of the population through sampling.

• Asian-Australasian Journal of Animal Sciences
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• 제15권12호
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• pp.1686-1689
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• 2002

Genetic gains and inbreeding coefficients in a Holstein MOET breeding population were predicted under different conditions relating to the distribution of the number of transferable embryos collected per flush using Monte Carlo simulation. The numbers of transferable embryos collected per flush were determined using five distributions (distributions 1, 3, 5, 7 and 9) with different aspects and similar means. Distributions 1, 3, 5, 7 and 9 were assumed to have gamma distribution's parameters ($\alpha$ and $\beta$) of (1 and 4.4), (3 and 1.47), (5 and 0.88), (7 and 0.63) and (9 and 0.49), respectively. Inbreeding rates were statistically significantly different among distributions but genetic gains were not. Relationships between inbreeding rates and variances of family size could be were clearly distinguished. The highest inbreeding coefficients were predicted in distribution 1 with the largest variance of family size, while distributions 5, 7 and 9 with smaller variance of family size had lower inbreeding coefficients.

• 한국통신학회논문지
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• 제35권2A호
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• pp.196-201
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• 2010

Measurement of Quality of Service (QoS) parameters and its statistical analysis becomes a key issue for Mobile WiMAX service providers to manage the converged network efficiently and to support end-to-end QoS. In this paper, we investigate the population distribution of end-to-end one-way delay which is the most important QoS parameter in Mobile WiMAX networks. The samples are analyzed with Chi-Square Goodness-of-Fit test, Kolmogorov-Smirnov (K-S), and Anderson-Darling (A-D) test to verify the distribution of parent population. The relation with confidence level and the minimum number of sample size is also performed for logistic distribution. The statistical analysis is a promising approach for measuring the performance Mobile WiMAX networks.