• Journal of the Korea Organic Resources Recycling Association
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• v.20 no.1
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• pp.78-86
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• 2012

In this study, dark fermentative hydrogen production (DFHP) from acid pretreated microalgal biomass was optimized with via statistical experimental design. Acid concentration and reaction time were varied from 0.1 to 3% (v/w) and 10 to 60 min with substrate concentration of 76 g dry cell weight (dcw)/L and initial pH of 7.4, respectively. During the fermentation, pH was not controlled. The optimal condition was found that at $H_{2}$ yield reached to 37.3 mL $H_{2}/g$ dcw at 1.2% HCl and 48 min. Through regression analysis, it was found that $H_{2}$ yield was well fitted by a quadratic polynomial equation ($R^{2}$=0.95). HCl concentration was the most significant factor influencing DFHP. The results of ANOVA verify that HCl concentration was the most significant factor influencing DFHP.

• Economic and Environmental Geology
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• v.18 no.4
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• pp.309-320
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• 1985

The crustal structure of the southern part of the Korean peninsula has been investigated based on the results of processing and anlaysis of gravity data. The processing techniques involve i) seperation of regional and residual anomalies by polynomial fittings, ii) power spectral analyses to determine the mean depth to the crustal base, iii) a filtering operation called "high-cut filtering and resampling," and iv) downward continuation to determine the undulation of the crustal base. The Bouguer anomalies show a lineation in the NE-SW direction which is the same as that of most mountains and tectonic lines of this area. The mean crustal depth is found to be 34km. The depth of the crustal base is varying in the estimated range of 26km to 36km with a thinner crust below the east coast than that of the west coast. The relief of the crustal base is appeared to be correlated with the regional surface topography. The linear regression relations computed between elevations and gravity anomalies indicate that the crust of this area seems to be not in perfect isostatic equilibrium but a little undercompensated state.

• Journal of Environmental Science International
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• v.26 no.6
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• pp.719-728
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• 2017

In order to investigate the adsorption characteristics for Sr ion using the Na-X zeolite synthesized from coal fly ash, batch tests and response surface analyses were carried out. The adsorption kinetic data for Sr ions, using Na-X zeolite, fitted well with the pseudo-second-order model. The uptake of Sr ions followed the Langmuir isotherm model, with a maximum adsorption capacity of 196.46 mg/g. Thermodynamic studies were conducted at different reaction temperatures, with the results indicating that Sr ion adsorption by Na-X zeolite was an endothermic (${\Delta}H^o$>0) and spontaneous (${\Delta}G^o$<0) process. Using the response surface methodology of the Box-Behnken method, initial Sr ion concentration ($X_1$), initial temperature ($X_2$), and initial pH ($X_3$) were selected as the independent variables, while the adsorption of Sr ions by Na-X zeolite was selected as the dependent variable. The experimental data fitted well with a second-order polynomial equation by multiple regression analysis. The value of the determination coefficient ($R^2=0.9937$) and the adjusted determination coefficient (adjusted $R^2=0.9823$) was close to 1, indicating high significance of the model. Statistical results showed the order of Sr removal based on experimental factors to be initial pH > initial concentration > temperature.

• Applied Chemistry for Engineering
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• v.29 no.3
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• pp.270-277
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• 2018

The adsorption of Eosin Y by the activated carbon (WCAC) prepared from waste citrus peel was investigated by using response surface methodology (RSM) and Box-Behnken design (BBD) statistical procedures. Experiments were carried out as per BBD with three input parameters, the Eosin Y concentration (Conc. : 30~50 mg/L), the solution temperature (Temp. : 293~313 K), and the adsorbent dose (Dose : 0.05~0.15 g/L). Regression analysis showed a good fit of the experimental data to the second-order polynomial model with coefficients of the determination ($R^2$) value of 0.9851 and P-value (Lack of fit) of 0.342. An optimum dye uptake of 59.3 mg/g was achieved at the dye concentration of 50 mg/L, the temperature of 333 K, and the adsorbent dose of 0.1056 g. The adsorption process of Eosin Y by WCAC can be well described by the pseudo second order kinetic model. The experimental data followed the Langmuir isotherm model.

• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.145-155
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• 2011

The objective of this study was to determine whether any pretreatment parameters were associated with pharmacological effect or toxicity parameters after vincristine administration and to describe a mathematical model, which explains the interpatient pharmacodynamic variability. The relationship between patient characteristics and vincristine dose and hematological toxicity were evaluated. 68 pediatric and adolescence patients and 107 adults with acute lymphoblastic leukemia were treated with vincristine $1.5mg/m^2/day$ IV and other anticancer drugs as scheduled. Complete blood counts and other blood test results were obtained. The input variables were age, gender, weight, lean body weight (LBW), height, body surface area, vincristine dose and total vincristine dose. The outcome measures were nadir values (white blood cells, absolute neutrophil counts, hemoglobin, and platelets); the absolute decrease, relative decrease, and survival fraction of blood cells. Polynomial regression analysis was carried out to determine the other significant covariates. The variability of $WBC_{nadir}$ was modeled with good precision and accuracy with a two-covariate model. This model should be validated and improved on with further clinical data. We believe that such pharmacodynamic modeling should be explored further to determine its performance and clinical relevance compared with modeling using pharmacokinetic parameter.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.2
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• pp.111-122
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• 2010

As the Jamsu-bridge and the floodplains of the Han River can be flooded during the rainy season, the exact prediction of the peak flood time is very important for mitigation of flood hazard. This study analyzes the effect of outflow of Paldang Dam and tide of Yellow Sea on the Han River. A target area is from the Paldang dam to Jeonryu gauging station. Water level of Jeonryu as a downstream boundary condition was estimated through multi linear regression analysis with outflow of Paldang dam and tide level of Incheon, because it was influenced by both a tide of Yellow Sea and outflow of Paldang dam. In this study, Water Level Rising Travel Time of the Jamsu-bridge and some floodplains in the Han River are estimated. Also, The second order polynomial expressions for relationships of outflow of Paldang Dam and Water Level Rising Travel Time were developed considering the outflow of Paldang dam and tide of Yellow Sea.

• Fisheries and Aquatic Sciences
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• v.17 no.1
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• pp.47-57
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• 2014

Thai Jasmine rice (Oryza sativa, long grain Indica var.) is popular in southeastern Asia and China due to its non-glutinous, fluffy texture and fragrant smell. However it has a high starch digestibility, which leads to an increased glycemic index (GI). Therefore it may require modified cooking methods for diabetes patients. The objectives of this study were to optimize the ratio of Thai Jasmine rice, sea tangle, and olive oil (CLTR) based on consumers' acceptance. The GI of plain cooked Thai Jasmine rice (CLR) was measured as a control. Sensory evaluation and response surface methodology were used to determine the optimal ratio. Texture analysis and nutritional evaluation were also performed on the optimal recipe of cooked Jasmine rice with sea tangle. A multiple regression equation was developed in quadratic canonical polynomial models. We used 26 trained Chinese panelists in their forties to rate color, flavor, adhesiveness, and glossiness, which we determined were highly correlated with overall acceptability. The optimal CLTR formula was 34.8% rice, 2.8% sea tangle, 61.9% water, and 0.5% olive oil. Compared to CLR, CLTR had a lower hardness, but a higher springiness and cohesiveness. However, CLR and CLTR had the same adhesiveness and chewiness. The addition of sea tangle and olive oil delayed retro-gradation of starch in CLTR and increased total dietary fiber, and protein and ash contents. The degree of gelatinization, and in vitro protein and starch digestibility of CLTR were lower than those of CLR. Based on Wolver' method, the GI of CLTR (52.9, incremental area under the glycemic-response curve, ignoring the area below fasting, as used for calculating the GI [Inc]) was lower compared with that of CLR (70.94, Inc), which indicates that CLTR is effective in decreasing and stabilizing blood glucose level, owing to its lower degree of gelatinization and starch digestibility. Our results show that CLTR can contribute to the development of a healthier meal for families and the fast food industry.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.6
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• pp.1-8
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• 2007

In this paper, research on joint optimization of the image spatial registration and the exposure compensation is conducted. The exposure compensation is performed in a frame work of the intensity compensation based on the polynomial approximation of the relationship between images. This compensation is jointly combined with the registration problem employing the Gauss-Newton nonlinear optimization method. In this paper, to perform for a simple and stable optimization, the block-coordinate method is combined with the Gauss-Newton optimization and extensively compared with the traditional approaches. Furthermore, regression analysis is considered in the compensation part for a better stable performance. By combining the block-coordinate method with the Gauss-Newton optimization, we can obtain a compatible performance reducing the computational complexity and stabilizing the performance. In the numerical result for a particular image, we obtain a satisfactory result for 10 repeats of the iteration, which implies a 50% reduction of the computational complexity. The error is also further reduced by 1.5dB compared to the ordinary method.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.11
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• pp.188-194
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• 2013

In this paper, we proposed a new method for pulmonary vessels image segmentation and refinement from pulmonary image. Proposed method consist of following five steps. First, threshold estimation is performed by polynomial regression analysis of histogram variation rate of the pulmonary image. Second, segmentation of pulmonary vessels object is performed by density-based segmentation method based on estimated threshold in first step. Third, 2D connected component labeling method is applied to segmented pulmonary vessels. The seed point of both side diaphragms is determined by eccentricity and size of component. Fourth step is diaphragm extraction by 3D region growing method at the determined seed point. Finally, noise cancelation of pulmonary vessels image is performed by 3D connected component labeling method. The experimental result is showed accurately pulmonary vessels image segmentation, the diaphragm extraction and the noise cancelation of the pulmonary vessels image.

• Food Science and Preservation
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• v.10 no.3
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• pp.314-319
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• 2003

This study was conducted to the optimize salting process of eggplant for development new product and enhancement quality for export. Three variables by five level central composite design and response surface methodology were used to determine optimum conditions for salting time, temperature and salt concentration. Optimization of the process was conducted using the combination of the moisture content, salinity and color of surface and inside of salted eggplant. The regression polynomial model was suitable (P>0.05) by Lack-of-Fit analysis with highly significant. To optimize the process, based on surface response and contour plots, the individual contour plots of the response variables were superimposed. The optimum conditions for this process were 6 days and 15$^{\circ}C$ at 30％ concentration under the optimum of restricted variables as moisture content was below 84％, salinity was below 14％, L and b value of surface were 10 to 20 and below 0, L value and b value of inside were 70 to 75 and 16 to 18.