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Effects of Polyporus Herbal-acupuncture at KI10 on LPS-induced nephritis in rats (LPS로 유도된 흰쥐의 신장염에 대한 음곡(KI10) 저령약침의 효과)

  • Lee, Jeong-Yun;Jang, Seung-Hoon;Jeon, Jong-Ik;Yim, Yun-Kyoung
    • The Journal of Korean Medicine
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    • v.36 no.3
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    • pp.73-83
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    • 2015
  • Objectives: The purpose of this study was to evaluate the effects of Polyporus Herbal-acupuncture(PO-HA) at KI10 (Umgok) on nephritis induced by lipopolysaccharide(LPS) in rats. Methods: Rats were allocated into normal, control, and 2 experimental groups. The rats in the control group were intra-peritoneally injected with LPS for nephritis induction. The rats in the groups of experiment 1 and experiment 2 were treated with Saline injection, and PO-HA, respectively at KI10 three times for a week and then intra-peritoneally injected with LPS. To evaluate the effects of PO-HA at KI10, WBC count in blood, creatine, tumor necrosis factor-alpha (TNF-${\alpha}$), cytokine-induced neutrophil chemoattractant 1(CINC-1) in serum, urinary volume, creatinine, total protein in urine, myeloperoxidase(MPO) in kidney were measured. Results: PO-HA at KI10 significantly suppressed the increase of WBC in blood, TNF-${\alpha}$, CINC-1 in serum, MPO in kidney of LPS-stimulated rats. PO-HA at KI10 significantly suppressed the increase creatinine, total protein in urine of LPS-stimulated rats. Conclusions: According to these results, it is postulated that PO-HA at KI10 has an anti-inflammatory and renal-protective effects on LPS-induced nephritis in rats. Therefore, it is suggested that PO-HA at KI10 may be an useful therapeutics for nephritis in clinical field after further researches.

Syntheses and Structures of Two Reduced Open-framework Titanophosphates

  • Zhao, Yongnan;Yu, Jianguo;Kwon, Young-Uk
    • Bulletin of the Korean Chemical Society
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    • v.29 no.4
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    • pp.805-810
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    • 2008
  • Using metallic Ti powder as raw materials and 1,2-diaminocyclohexane (DACH) as the trial template, two novel reduced titanophosphate open-structures were hydrothermally isolated by varying the $H_3PO_4/H_2O$ ratio to adjust the pH value. TiPO-1 crystallizes in orthorhombic Pbca space group with cell parameters a = 21.956(3) $\AA$, b = 8.6268(11) $\AA$, c = 7.2883(9) $\AA$, V = 1380.5(3) $\AA^3$, Z = 4. TiPO-2 crystallizes in triclinic space group P$\bar{1}$ with parameters a = 5.1620(10) $\AA$, b = 8.815(2) $\AA$, c = 10.655(3) $\AA$, $\alpha$ = $99.45^{\circ}$, $\beta$ = $102.94^{\circ}$, $\gamma$ = $91.06^{\circ}$, V = 465.34 $\AA^3$. TiPO-1 is constructed by infinite -Ti-O-Ti-O- linkage that is capped by $PO_4$ groups to form a chain structure with protonated DACH molecules occupying the interchain spaces. TiPO-2 represents a rare 3-D reduced titanophosphate with 12-MR channels. The structure of TiPO-2 is a neutral framework with water molecules located in the channels.

Li Ion Diffusivity and Rate Performance of the LiFePO4 Modified by Cr Doping

  • Park, Chang-Kyoo;Park, Sung-Bin;Shin, Ho-Chul;Cho, Won-Il;Jang, Ho
    • Bulletin of the Korean Chemical Society
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    • v.32 no.1
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    • pp.191-195
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    • 2011
  • This study reports the root cause of the improved rate performance of $LiFePO_4$ after Cr doping. By measuring the chemical diffusion coefficient of lithium ($D_{Li}$) using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS), the correlation between the electrochemical performance of $LiFePO_4$ and Li diffusion is acquired. The diffusion constants for $LiFePO_4$/C and $LiFe_{0.97}Cr_{0.03}PO_4$/C measured from CV are $2.48{\times}10^{-15}$ and $4.02{\times}10^{-15}cm^2s^{-1}$, respectively, indicating significant increases in diffusivity after the modification. The difference in diffusivity is also confirmed by EIS and the $D_{Li}$ values obtained as a function of the lithium content in the cathode. These results suggest that Cr doping facilitates Li ion diffusion during the charge-discharge cycles. The low diffusivity of the $LiFePO_4$/C leads to the considerable capacity decline at high discharge rates, while high diffusivity of the $LiFe_{0.97}Cr_{0.03}PO_4$/C maintains the initial capacity, even at high C-rates.

Metal-defined Electro-Optic Polymer Waveguide Operating at both $1.31{\mu}m$ and $1.55{\mu}m$ Wavelength ($1.31{\mu}m$ and $1.55{\mu}m$ 파장에서 금속 defined Electro-Optic Polymer Waveguide)

  • Park, G.C.;Lee, J.;Chung, H.C.;Jeong, W.J.;Yang, H.H.;Yoon, J.H.;Park, H.R.;Gu, H.B.;Lee, K.S.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.05c
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    • pp.21-23
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    • 2004
  • We report experimental results demonstrating a novel metal defined polymer optical waveguide with a low loss in electro-optic polymers for the first time. The polymer optical waveguides are created using a metal film on the top of upper cladding without any conventional etching process. The fabricated waveguides have an excellent lateral optical mode confinement at both 1.31 ${\square}m$ and 1.55 ${\square}m$ wavelength, resulting in a fiber-to lens optical insertion loss of ~ 7 dB at 1.55 ${\square}m$ and ~4.5 dB at 1.31 ${\square}m$ wavelength in a 3.5cm total length for TM polarizations, respectively. We also present the optical loss dependence of the waveguide as a function of optical wavelengths. These results may be used in the complex design of integrated polymer optical circuits that need simpler and cheaper fabrication process.

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Effects of N & P Treatment Based on Liquid Organic Materials for Capacitive Deionization(CDI) (축전식 탈염 공정의 액상 유기물에 따른 질소(N) 및 인(P) 처리 특성)

  • Lee, Bo-Ram;Jeong, In-Jo;Park, Soo-Gil
    • Journal of the Korean Electrochemical Society
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    • v.16 no.3
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    • pp.123-128
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    • 2013
  • Organic carbons such as methanol, ethanol, iso-propanol, methoxy ethanol, glucose are added(1, 2, 3%) in the 2000 ppm $NH_3$ and $H_3PO_4$. As vol.%. cyclic voltammetry measurement of the capacity with the addition of organic carbon, the results of $NH_3$ + 3 vol.% Methanol Addition, $H_3PO_4$ + 2 vol.% iso-propanol addition of the increase in capacity was observed. Applying to the CDI Module cell with an addiction of organic carbon is confirm that remove $NH_4$-N and $PO_4$-P in sewage. Namely, the removal efficiency of $NH_3$ was increase of 16.4% during adsorption, 30.4% during desorption and the removal efficiency of $H_3PO_4$ was increase of 63% during adsorption, 54.7% during desorption. Therefore, the result of this research is confirm that effect of the N, P removal and considered that reduction of the operating costs without removing the organic matter in the influent wastewater.

Viral Effects of a dsRNA Mycovirus (PoV-ASI2792) on the Vegetative Growth of the Edible Mushroom Pleurotus ostreatus

  • Song, Ha-Yeon;Choi, Hyo-Jin;Jeong, Hansaem;Choi, Dahye;Kim, Dae-Hyuk;Kim, Jung-Mi
    • Mycobiology
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    • v.44 no.4
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    • pp.283-290
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    • 2016
  • A double-stranded RNA (dsRNA) mycovirus was detected in malformed fruiting bodies of Pleurotus ostreatus strain ASI2792, one of bottle cultivated commercial strains of the edible oyster mushroom. The partial RNA-dependent RNA polymerase (RdRp) gene of the P. ostreatus ASI2792 mycovirus (PoV-ASI2792) was cloned, and a cDNA sequences alignment revealed that the sequence was identical to the RdRp gene of a known PoSV found in the P. ostreatus strain. To investigate the symptoms of PoV-ASI2792 infection by comparing the isogenic virus-free P. ostreatus strains with a virus-infected strain, isogenic virus-cured P. ostreatus strains were obtained by the mycelial fragmentation method for virus curing. The absence of virus was verified with gel electrophoresis after dsRNA-specific virus purification and Northern blot analysis using a partial RdRp cDNA of PoV-ASI2792. The growth rate and mycelial dry weight of virus-infected P. ostreatus strain with PoV-ASI2792 mycovirus were compared to those of three virus-free isogenic strains on 10 different media. The virus-cured strains showed distinctly higher mycelial growth rates and dry weights on all kinds of experimental culture media, with at least a 2.2-fold higher mycelial growth rate on mushroom complete media (MCM) and Hamada media, and a 2.7-fold higher mycelial dry weight on MCM and yeast-malt-glucose agar media than those of the virus-infected strain. These results suggest that the infection of PoV mycovirus has a deleterious effect on the vegetative growth of P. ostreatus.

A Study on Graduate Attributes Assessment for K-EP (K-Engineering Professional) Qualification (K-EP(K-Engineering Professional) 자격을 위한 졸업생역량 평가방안 연구)

  • Choi, Se Hyu;Kang, Sang Hee;Kim, Jung Soo;Yoon, Jiyoung
    • Journal of Engineering Education Research
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    • v.24 no.6
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    • pp.30-39
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    • 2021
  • The present study aims to demonstrate that it is possible to objectively evaluate the competency (referred to as graduate attributes or program outcomes) of graduates of engineering education programs. To strengthen the link between engineering education accreditation and the qualification/certification system of engineering professionals, referred to as K-Engineering Professional (K-EP), individually assuring the quality of accredited graduates using multiple-choice test as main assessment tool is proposed. Test questions related to the basic vocational skills of NCS are developed for seven of the 10 program outcomes of the ABEEK KEC2015. The three program outcomes, PO1, PO3, and PO5, which need to fully accommodate the characteristics of each disciplinary field, are excluded. A pilot test involving graduates of eight accredited programs is conducted. Applying on Rasch model based on Item Response Theory (IRT), the item difficulty, fit and discrimination of multiple choice test are demonstrated. The pilot study strongly suggests that individual competency evaluation is possible at a certain level for seven program outcomes tested. For PO1, PO3, and PO5, however, questions that address the characteristics of each disciplinary field need to be devised. If a suitable pool of questions is built, it can be used as a program outcomes assessment tool by the accredited programs.

Dosimetric and Radiobiological Evaluation of Dose Volume Optimizer (DVO) and Progressive Resolution Optimizer (PRO) Algorithm against Photon Optimizer on IMRT and VMAT Plan for Prostate Cancer

  • Kim, Yon-Lae;Chung, Jin-Beom;Kang, Seong-Hee;Eom, Keun-Yong;Song, Changhoon;Kim, In-Ah;Kim, Jae-Sung;Lee, Jeong-Woo
    • Progress in Medical Physics
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    • v.29 no.4
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    • pp.106-114
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    • 2018
  • This study aimed to compare the performance of previous optimization algorithms against new a photon optimizer (PO) algorithm for intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans for prostate cancer. Eighteen patients with prostate cancer were retrospectively selected and planned to receive 78 Gy in 39 fractions of the planning target volume (PTV). All plans for each patient optimized with the dose volume optimizer (DVO) and progressive resolution optimizer (PRO) algorithms for IMRT and VMAT were compared against plans optimized with the PO within Eclipse version 13.7. No interactive action was performed during optimization. Dosimetric and radiobiological indices for the PTV and organs at risk were analyzed. The monitor units (MU) per plan were recorded. Based on the plan quality for the target coverage, prostate IMRT and VMAT plans using the PO showed an improvement over DVO and PRO. In addition, the PO generally showed improvement in the tumor control probability for the PTV and normal tissue control probability for the rectum. From a technical perspective, the PO generated IMRT treatment plans with fewer MUs than DVO, whereas it produced slightly more MUs in the VMAT plan, compared with PRO. The PO showed over potentiality of DVO and PRO whenever available, although it led to more MUs in VMAT than PRO. Therefore, the PO has become the preferred choice for planning prostate IMRT and VMAT at our institution.

Analysis of post-annealing effect and electrical properties of Li3PO4/SiC (Li3PO4/SiC의 후열처리에 의한 영향 및 전기적 특성 분석)

  • Lee, Hyung-Jin;Kim, Minkyung;Oh, Jong-Min;Shin, Weon-Ho;Park, Chulhwan;Koo, Sang-Mo
    • Journal of IKEEE
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    • v.26 no.2
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    • pp.232-239
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    • 2022
  • We analyzed the effect of post-annealing on lithium phosphate (Li3PO4) solid-state thin-film. Li3PO4 thin films were deposited by radio frequency (RF) sputtering, with subsequent annealing of the films at 200-400 ℃. SEM imaging of the sample surfaces showed no significant difference in morphology between the annealed and non-annealed samples. XRD analysis indicated that the samples consist of an amorphous-like structure. Post-annealing changes in binding energy were confirmed by XPS analysis, while the leakage current density at -6 V was measured to be about 7.15 times lower in a device that had been annealed at 400 ℃ vs a non-annealed device. It was confirmed that the leakage current decreased with increasing post-annealing temperature.

Development of a 3D Virtual Fashion Design by Applying the PO Method -With a Focusing on the T-shirt Design- (PO 발상법을 적용한 3D 가상 패션디자인 개발 -티셔츠 디자인을 중심으로-)

  • Suh, Seunghee
    • Journal of Fashion Business
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    • v.25 no.5
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    • pp.73-87
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    • 2021
  • This study aimed to develop fashion designs by applying the PO (Provocative Operation) method as a 3D virtual clothing program and to derive the PO application method in fashion design. The first T-shirt design was presented as an existing thinking method, and the second design was developed by applying escape, reversal, exaggeration, distortion, and hopeful thinking techniques, which are techniques for 'provocation' of the PO method, to the first design. Thus, 18 T-shirt designs were developed as 3D virtual clothing, with 3 sets of 6 designs, including the 1st and 2nd designs. The method of using the 'provocation' techniques of the PO method in the development of fashion design derived from this was as follows. First, the 'escape' technique was designed in such a way that a part of the detail or structure was deleted, or a part of the structure or expression element of another item was applied. Second, the 'inversion' technique was expressed by inverting the position or shape of a detail or structure up, down, left, and right; fitting the structural detail or reversing the shape; or converting the structure and form. Third, the 'exaggeration' technique exaggerated the size, length, and volume of a structure's form or detail. Fourth, the 'distortion' technique was expressed as a distortion of lines or shapes or a visual distortion using the Trompe l'oeil technique. Fifth, the 'hopeful thinking' technique was developed and expressed from the idea of an hypothetical 'if' it was absurd, irrational, and unrealistic.