• Title/Summary/Keyword: plant medicines

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Application of Domestic Bamboo Stems Mainly for Inner Beauty Product Development: A Review (이너뷰티 제품 개발을 중심으로 국내산 대나무 줄기의 생물공학적 활용방안)

  • Choi, Moon-Hee;Seo, Yeong-Jin;Shin, Hyun-Jae
    • KSBB Journal
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    • v.32 no.1
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    • pp.1-8
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    • 2017
  • Bamboo is a plant belonging to the Gramineae family, and can be used as valuable bioresources for many industrial applications. Bamboo has some useful properties and having a lot of beneficial uses such as a bamboo ware, agriculture material, building construction material, pulpwood, etc. Bamboo stem has a large amount of active ingredients that those of bamboo leaves. The stem of bamboo can be processed into various biomaterials including cellulose and lignin, and sometimes uses as foods, cosmetics and medicines using stem extracts with polyphenol compounds. For cosmetic applications of bamboo stems, especially, the constituents of bamboo stem are suitable for inner beauty (cosmetic food) products showing antioxidant and UV-protecting activities. This review summaries the recent literature data and discusses the versatile uses of bamboo stem and its extracts mainly for cosmetic application.

Curcumin: a Polyphenol with Molecular Targets for Cancer Control

  • Qadir, Muhammad Imran;Naqvi, Syeda Tahira Qousain;Muhammad, Syed Aun
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2735-2739
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    • 2016
  • Curcumin, is a polyphenol from Curcuma longa (turmeric plant), is a polyphenol that belongs to the ginger family which has long been used in Ayurveda medicines to treat various diseases such as asthma, anorexia, coughing, hepatic diseases, diabetes, heart diseases, wound healing and Alzheimer's. Various studies have shown that curcumin has anti-infectious, anti-inflammatory, anti-oxidant, hepatoprotective, thrombosuppressive, cardio protective, anti-arthritic, chemo preventive and anti-carcinogenic activities. It may suppress both initiation and progression stages of cancer. Anticancer activity of curcumin is due to negative regulation of inflammatory cytokines, transcription factors, protein kinases, reactive oxygen species (ROS) and oncogenes. This review focuses on the different targets of curcumin to treat cancer.

Phytochemical Compounds from the Ethanolic Extract of Gymnema sylvestre, Senna auriculata and Cissus quadrangularis through GC-MS Analysis

  • Sindhuja G;Mary Agnes A
    • Mass Spectrometry Letters
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    • v.14 no.2
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    • pp.25-35
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    • 2023
  • Plants are a traditional source of many chemicals used as biochemical, flavors, food, color, and pharmaceuticals in various countries, especially India. Most herbal medicines and their derivatives are often made from crude extracts containing a complex mixture of various phytochemical chemical components (secondary metabolites of the plants). This study aimed to identify bioactive compounds from the different parts of the plant from the ethanolic extract of Gymnema sylvestre, Senna auriculata, and Cissus quadrangularis (leaves, flower, stem) by gas chromatography-mass spectroscopy (GC-MS). The gas chromatography - mass spectrometry analysis revealed the presence of various compounds like 3,4-dimethylcyclohexanol, hexanoic acid, D-mannose, and N-decanoic acid. Hence, the Gymnema sylvestre, Senna auriculata, and Cissus quadrangularis may have chemopreventive, anti-cancer, anti-microbial activity, antioxidant, anti-diabetic activity, anti-inflammatory, and antifungal due to the presence of secondary metabolites in the ethanolic extract. These phytochemicals are supported for traditional use in a variety of diseases.

Monitoring of total ash, acid-insoluble ash and heavy metals content contained in herbal medicines classified by parts used (한약재의 약용부위에 따른 회분, 산불용성회분 및 중금속 함량)

  • Kim, Dong-Gyu;Kim, Kyung-Sik;Lee, Sung-Deuk;Jung, Kweon;Park, Seung-Kook
    • Analytical Science and Technology
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    • v.27 no.2
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    • pp.114-120
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    • 2014
  • The aim of this study was to investigate of total ash, acid-insoluble ash and heavy metals content contained in commercial herbal medicines classified by parts used. A total of 1504 samples (84 species) purchased from markets in Seoul, are classified by five kinds of plant parts. The mean of total ash and acidinsoluble ash content (%) were as follows; Herba 9.0, 1.1, Caulis and cortex 6.1, 1.0, Flos fructus and semen 5.1, 0.8, Radix 4.6, 0.7 and Rhizoma 4.3, 0.4. The total amount of individual heavy metals content (mg/kg) (Pb, As, Cd and Hg) was high in Herba 1.13 and decreased in the order of Caulis and cortex 1.07, Rhizoma 0.91 and Radix 0.91, and was low in Flos fructus and semen 0.73. In addition, acid-insoluble ash contents was correlated with the total amount of individual heavy metals (r=0.314) (p<0.01).

Development of ITS sequence based SCAR marker and multiplex-SCAR assay for the rapid authentication of Tetrapanacis Medulla and Akebiae Caulis (통초(通草), 목통(木通) 신속 감별용 ITS 염기서열 기반 SCAR 마커 및 Multiplex-SCAR 분석법 개발)

  • Noh, Pureum;Kim, Wook Jin;Park, Inkyu;Yang, Sungyu;Choi, Goya;Moon, Byeong Cheol
    • The Korea Journal of Herbology
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    • v.36 no.1
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    • pp.9-17
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    • 2021
  • Objectives : Tetrapanacis Medulla and Akebiae Caulis are one of the most frequently adulterated herbal medicines because of their confusability of terms in the ancient writings and the similarity of morphological features of dried herbal products. The major adulterant is Aristolochia manshuriensis (Guanmutong) which has a serious safety concern with its toxicity. To ensure the safety and quality of the two herbal medicines, it is necessary to discriminate the toxic adulterant from authentic species. The aim of this study is to develop SCAR markers and to establish the multiplex-SCAR assay for discrimination of four plant species related to Tetrapanacis Medulla and Akebiae Caulis. Methods : ITS regions of fifteen samples of four species (Tetrapanax papyrifer, Fatsia japonica, Aristolochia manshuriensis, and Akebia quinata) collected from different sites were amplified and sequenced. Fifteen obtained ITS sequences were aligned and analysed for the detection of species-specific sequence variations. The SCAR markers were designed based on the sequence alignments and then, multiplex-SCAR assay enhancing rapidity was optimized. Results : ITS sequences clearly distinguished the four species at the species level. The developed SCAR markers and multiplex-SCAR assay were successfully discriminated four species and detected the adulteration of commercial product samples by comparison of the amplified DNA fragment sizes. Conclusions : These SCAR markers and multiplex-SCAR assay are a rapid, simple, and reliable method to identify the authentic Tetrapanacis Medulla and Akebiae Caulis from adulterants. These genetic tools will be useful to ensure the safety and to standardize the quality of the two herbal medicines.

Carotenoids Biosynthesis and Their Metabolic Engineering in Plants (식물에서 Carotenoid 생합성 경로와 대사공학적 응용)

  • Ha, Sun-Hwa;Kim, Jung-Bong;Park, Jong-Sug;Ryu, Tae-Hun;Kim, Kyung-Hwan;Hahn, Bum-Soo;Kim, Jong-Bum;Kim, Youg-Hwan
    • Journal of Plant Biotechnology
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    • v.30 no.1
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    • pp.81-95
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    • 2003
  • Carotenoids are synthesized from the plastidic glyceraldehyde-3-phosphate (GAP)/pyruvate pathway in isoprenoids biosynthetic system of plants. They play a crucial role in light harvesting, work as photoprotective agents in photosynthesis of nature, and are also responsible for the red, orange and yellow colors of fruits and flowers in plants. In addition to biological actions of carotenoids as antioxidants and natural pigments, they are essential components of human diet as a source of vitamin A. It has been also suggested that some kinds of carotenoids might provide protection against cancer and heart disease as human medicines. In this article, we review the commercial applications on the basis of biological functions of carotenoids, summarize the studies of genes involved in the carotenoid biosynthetic pathway, and introduce recent results achieved in metabolic engineering of carotenoids. This effort for understanding the carotenoids metabolism will make us to increase the total carotenoid contents of crop plants, direct the carotenoid biosynthetic machinery towards other useful carotenoids, and produce a new array of carotenoids by further metabolizing the new precursors that are created when one or two key enzymes in carotenoid biosynthetic pathway are exchanged through gene manipulation in the near future.

The Use of qNMR for Quality Control of Coumarin-based Pharmaceuticals and Plant Medicines

  • Crocoli, Luana C.;Molon, Vinicius B.;Moura, Sidnei
    • Natural Product Sciences
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    • v.27 no.2
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    • pp.128-133
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    • 2021
  • The Coumarin (1,2-benzopyrone) is the main secondary metabolite of Mikania laevigata Sch. Beep ex Baker and Mikania glomerata Spreng., which are popularly known as guaco. These plants have been used mainly in traditional medicine in the treatment of respiratory diseases because their bronchodilator effect. However, there are around 200 species of Mikania, which are quite similar in appearance. From these, only M. leavigata and M. glomerata have high concentrations of coumarins. In this line, the falsification of products Mikania based has been frequent. In this sense, this work demonstrated the application of the easy, fast, e not destructive method based in Nuclear Magnetic Resonance in quantitative mode (qNMR) for the determination of coumarin in both commercial and homemade guaco products. Thus, in the first step the compounds were extract from guaco leaves and syrups using chloroform (CHCl3), with or without ultrasound. About the method, was linear with a R2 = 0.9947 for 1,2-benzopyrone, with detection and quantification limits with were 0.11 and 0.36 mg mL-1 respectively. In the same line, the method was safe with RSD <0.3% and with recovery ranging from 93-101%. To confirm the applicability of the method, in the last step was applied to 10 real samples (6 from leaves and 4 from syrups). The content of the coumarin in the leaf extract ranged from 0.62 to 1.30 mg mL-1. For syrups I, II and IV, the content of coumarin was in accordance with the manufacturers. However, for de Syrup III, the concentration was 155% higher. In summary, the qNMR is a rapid method with minimal sample preparation that can be used to quantify coumarin in home-made plant extracts as well as in commercial samples as syrup for instance. This method is applicable for quality control of different plants-based products.

Spatio-temporal Moth Diversity (Insecta: Lepidoptera) of Mt. Baegun-san, Gwangyang, Jeonnam (전라남도 광양시 백운산 나방 (곤충강: 나비목)의 시공간적 다양성 연구)

  • Choi, Sei-Woong;Nho, Dong-Ho;Kim, Sang-Soo;Hong, Kee-Jeong
    • Korean Journal of Ecology and Environment
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    • v.49 no.1
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    • pp.62-66
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    • 2016
  • This study was aimed to investigate the elevational and seasonal variation of moth diversity of Mt. Baegun-san, Gwangyang-city, Jeonnam. Moth collecting was carried out using a UV light trap at three different elevational sites from September to October 2014 and from April to October 2015 (9 times) except winter. A total of 288 moth species and 1,444 individuals in 15 families were identified. Geometridae (97 species and 740 individuals) were the most dominant in the numbers of species and individuals, followed by Noctuidae (62 species, 193 individuals), Erebidae (52 species, 177 individuals) and Notodontidae (16 species, 111 individuals). Elevational change showed that the lower elevation, the higher number of species and individuals. Seasonal change of numbers of species and individuals showed the M-shaped pattern with June and August peaks. Compared to the previous records from historical literatures, 197 species were newly added and the total moth species richness of Mt. Baegun-san comprised 449 species in 20 families. The Chao 2 estimated number of species using the observed species including unpublished data set was 1,530 species that comprised about 43% of the Korean Lepidopteran fauna. This large number of estimated species requested the more extensive and long-term survey for better understanding of the total moth fauna in this area.

Anatomical Characteristics of Korean Mistletoe [Viscum album var. coloratum(Kom.) Ohwi] Stem (한국산 겨우살이 수간의 조직특성)

  • Lee, Bo-Duk;Park, Beyung-Su
    • Korean Journal of Plant Resources
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    • v.22 no.4
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    • pp.287-292
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    • 2009
  • Recently, the consumption of mistletoe[Viscum album var. coloratum(Kom.) Ohwi] is increasing because of its good medical effectiveness with the increased concern on the natural medicines and foods. The result obtained from the investigation on the stem tissues of the mistletoe and the oriental chestnut oak, a host plant species, are as follows. Haustorium from the seeds of the mistletoe after their sticking to the branches of the host plant penetrates into the bark where it forms the endophyte system through the active cell division. The endophyte grown in the cambium of the host plant makes the stems and leaves as the outer tissues in a certain time. Even through lignification of the host wood in the branches the oriental chestnut oak was not progressive, its tylosis coas developed partially assembly due to the formation of the endophyte. The stems of the mistletoe consisted of vascular tracheid, selereid, and ray and axial parenchyma, classified as a hardwood without vessels. The vascular tracheids seemed to take a role instead of the vessels in the mistletoe plant from the result that the pits of the vessels in the host branches are linked to the vessel-form tracheid in the mistletoe stems. The constituent ratio of the sclereid cells in the mistletoe stems increased with aging. Furthermore their ratio of the parenchyma cells was higher, which contained the more cell content, compared with the cells of the general woody plant species.

Effects of Organic Matter Concentration in Soil on Phytoavailability of Cadmium in Medicinal Plants

  • Noh, Yong-dong;Kim, Kwon-Rae;Kim, Won-Il;Jung, Ki-Yuol;Hong, Chang Oh
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.5
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    • pp.319-325
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    • 2015
  • The safety of plant species used as a source for herbal medicines and dietary supplements has recently been questioned due to poisonings associated with the presence of cadmium (Cd) in these plants. These plants can derive Cd from their presence in the soil. Organic matter (OM) concentrations in soils could affect the availability of Cd for plants. To determine the effect of OM concentration in soil on the concentration of plant available Cd and uptake of this toxic element by medicinal plants, soil and plant samples were collected from 102 fields supporting for 5 species of medicinal plants in 6 province of South Korea. Concentrations of OM and dissolved organic carbon (DOC) in soils affected the phytoavailability of Cd. One M $NH_4OAc$ extractable Cd concentration in soil increased with increasing OM concentrations. There were significantly positive relationships between 1 M $NH_4OAc$ extractable Cd concentration and OM concentration in soil and between 1 M $NH_4OAc$ extractable Cd concentration and DOC concentration. Likewise, OM and DOC concentrations significantly affected Cd concentration in medicinal plant soils. Cadmium concentration in medicinal plants increased with increasing OM concentration in soil [Cd concentration $(mg\;kg^{-1})= 0.179+1.424{\times}10^{-3}$ OM concentrations, $R^2=0.042*$] and with DOC concentration [Cd concentration $(mg\;kg^{-1})= 0.150+5.870{\times}10^{-4}$ DOC concentrations, $R^2=0.124***$]. These results might result from Cd-DOC complex which is easily absorbed Cd form by plant root. Dissolved organic carbon concentration had more positive relationship with Cd concentration in medicinal plants and 1 M $NH_4OAc$ extractable Cd concentration in soils than OM. Cadmium concentration in all 5 species of medicinal plant (Atractylodes macrocephala Koidzumi, Astragalus membranaceus, Codonopsis lanceolata, Platycodon grandiflorum, and Rehmannia glutinosa) significantly increased with increasing DOC concentration in soil. From the above results, formation of Cd-DOC complex caused by OM application might be mainly attributed to increase in Cd concentration in medicinal plants.