Browse > Article
http://dx.doi.org/10.5806/AST.2014.27.2.114

Monitoring of total ash, acid-insoluble ash and heavy metals content contained in herbal medicines classified by parts used  

Kim, Dong-Gyu (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Kim, Kyung-Sik (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Lee, Sung-Deuk (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Jung, Kweon (Seoul Metropolitan Government Research Institute of Public Health and Environment)
Park, Seung-Kook (Department of Food Science and Biotechnology, Institute of Life Science and Resources, Kyung Hee University)
Publication Information
Analytical Science and Technology / v.27, no.2, 2014 , pp. 114-120 More about this Journal
Abstract
The aim of this study was to investigate of total ash, acid-insoluble ash and heavy metals content contained in commercial herbal medicines classified by parts used. A total of 1504 samples (84 species) purchased from markets in Seoul, are classified by five kinds of plant parts. The mean of total ash and acidinsoluble ash content (%) were as follows; Herba 9.0, 1.1, Caulis and cortex 6.1, 1.0, Flos fructus and semen 5.1, 0.8, Radix 4.6, 0.7 and Rhizoma 4.3, 0.4. The total amount of individual heavy metals content (mg/kg) (Pb, As, Cd and Hg) was high in Herba 1.13 and decreased in the order of Caulis and cortex 1.07, Rhizoma 0.91 and Radix 0.91, and was low in Flos fructus and semen 0.73. In addition, acid-insoluble ash contents was correlated with the total amount of individual heavy metals (r=0.314) (p<0.01).
Keywords
herbal medicines; total ash; acid-insoluble ash; heavy metals;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 H. K. Kim, '대한약전의 해설서', p522, Pamakoreana, Seoul, Korea, 2004.
2 S. D. Lee and Y. C. Park, 'Toxicology for herbal medicine (in Korean)', p42, KSI Publishers, Paju, Korea, 2012.
3 K. Chan, Chemosphere, 23, 1361-1371 (2003).
4 S. M. Choi, H. J. Chung, Y. S. Yoon, M. Y. Lee, H. S. Choi and H. J. Sung, J. Korean Oriental Med., 21(3), 99-112 (2000).
5 P. K. Mukherjee, 'Quality control of herbal Drugs, An Approach to evaluation of botanicals', p112, Business Horizon, New Delhi, India, 2012.
6 I, Ahmad, F. Aqil, and M. Owais, 'Modern phytomedicine, Turning medicinal plants into drugs', p25, Wiley- VCH, Weinheim, Germany, 2006.
7 홍남두, 김남재, '한약의 품질관리', p206, 신일상사, 서울, 2007.
8 P. K. Mukherjee, 'GMP for botanicals, Regulatory and quality issues on phytomedicines', p59, Business Horizon, New Delhi, India, 2012.
9 S. J. Jung, S. T. Kang, C. H. Han, S. J. Kim, S. K. Ko, Y. H. Kim, Y. K. Kim, B. S. Kim, and B. H. Choi, J. Fd. Hyg. Safety, 25(4), 402-409 (2010).
10 KFDA, 'The Korean herbal pharmacopoeia', KFDA press, Seoul, Korea, 2012.
11 식품의약품안전청, 생약 등의 잔류오염물질 기준 및 시험방법(제2012-42호).
12 J. Wu, Y. Tan, Y. Wang, and R. Xu, J. Nat. Med., 65(3-4), 656-661 (2011).   DOI
13 M. R. Gomez, S. Cerutti, L. L. Sombra, M. F. Silva, and L. D. Martinez, Food Chem.Toxicol., 45, 1060-1064 (2007).   DOI   ScienceOn
14 B. I. Seo, J. H. Lee, H. Y. Choi, D. R. Gwon, and Y. M. Bu, 'Herbal medicines (in Korean)', p29, Yeongrimsa publishers, Seoul, Korea, 2006.
15 식품의약품안전청, '한약재표준제조공정지침', p3, 서울, 2008.
16 안덕균, '한국본초도감', 교학사, 서울, 2000.
17 C. H. Park and S. I. Kang, 'Processing technology of herbal medicines (in Korean)', p32, Chengmoongak publishers, Seoul, Korea, 2006.
18 D. G. Kim, B. S. Kim, Y. C. Kim, Y. O. Hwang, Y. Z. Chae, and S. K. Park, Nat. Prod. Sci., 17(1), 38-44 (2011).
19 KFDA, 'The Korean pharmacopoeia tenth edition', KFDA press, Seoul, Korea, 2012.
20 R. B. Saper, S. N. Kales, J. Paquin, M. J. Burns, D. M. Eisenberg, R. B. Davis, and R. S. Phillips, J.A.M.A., 292(23), 2868-2873 (2004).   DOI   ScienceOn