• Journal of Sensor Science and Technology
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• v.31 no.6
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• pp.389-396
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• 2022

Quartz crystal microbalance (QCM) based sensors are used for various applications owing to advantages such as excellent accuracy and precision, rapid response, and tiny footprint. Traditional applications of QCM-based sensors include biological sensing and thin-film thickness monitoring. Recently, QCMs have been used as functional material for novel physical and chemical detections, and with improved device design. QCM-based sensors are garnering considerable attention in particulate matter sensing and electric nose application. This review covers the challenges and solutions in physical, chemical, and biological sensing applications. First, various physical sensing applications are introduced. Secondly, the toxic gas and chemical detection studies are outlined, focusing on introducing a coating method for uniform sensing film and sensing materials for a minimal damping effect. Lastly, the biological and medical sensing applications, which use the monomolecularly decorating method for biomolecule recognition and a brief description of the overall measuring system, are also discussed.

• Journal of Korean Biological Nursing Science
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• v.15 no.2
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• pp.54-64
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• 2013

Purpose: This study aimed to analyze the effects and intervention methods of aromatherapy studies in nursing. Methods: A systematic literature review was conducted. Nursing literature databases were searched to identify intervention studies published in Korea between 2000 and 2011. Finally, 53 articles were included in the review. Results: The most preferred application method of aromatherapy was massage. The major dependent variables were anxiety, depression, pain, and sleep disturbance. 76.5% of the studies reported positive effects on anxiety. 93.8% of the studies reported positive effects on depression. 86.7% of the studies reported positive effects on pain. 92.3% of the studies reported positive effects on sleep disturbance. Psychometric measurements were mainly used in the studies. Only 33.9% of the studies adopted physical or physiological measurements. The most prevalent physical or physiological instrument was vital signs. Conclusion: Aromatherapy had positive effects on anxiety, depression, pain, and sleep disturbance measuring when using psychometric instruments. However, there was no sufficient evidence measuring when using physical or physiological instruments. These need to be studied using well-designed, randomized, controlled trials, and should encourage the use of both psychometric and physiological measures for aromatherapy intervention in nursing studies.

• Genomics & Informatics
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• v.17 no.1
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• pp.11.1-11.7
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• 2019

Athletic performance is a complex multifactorial trait involving genetic and environmental factors. The heritability of an athlete status was reported to be about 70% in a twin study, and at least 155 genetic markers are known to be related with athlete status. Mitochondrial DNA (mtDNA) encodes essential proteins for oxidative phosphorylation, which is related to aerobic capacity. Thus, mtDNA is a candidate marker for determining physical performance. Recent studies have suggested that polymorphisms of mtDNA are associated with athlete status and/or physical performance in various populations. Therefore, we analyzed mtDNA haplogroups to assess their association with the physical performance of Korean population. The 20 mtDNA haplogroups were determined using the SNaPshot assay. Our result showed a significant association of the haplogroup F with athlete status (odds ratio, 3.04; 95% confidence interval, 1.094 to 8.464; p = 0.012). Athletes with haplogroup F ($60.64{\pm}3.04$) also demonstrated a higher Sargent jump than athletes with other haplogroups ($54.28{\pm}1.23$) (p = 0.041). Thus, our data imply that haplogroup F may play a crucial role in the physical performance of Korean athletes. Functional studies with larger sample sizes are necessary to further substantiate these findings.

• Clinical and Experimental Vaccine Research
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• v.13 no.2
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• pp.73-82
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• 2024

DNA cancer vaccines as an approach in tumor immunotherapy are still being investigated in preclinical and clinical settings. Nevertheless, only a small number of clinical studies have been published so far and are still active. The investigated vaccines show a relatively stable expression in in-vitro transfected cells and may be favorable for developing an immunologic memory in patients. Therefore, DNA vaccines could be suitable as a prophylactic or therapeutic approach against cancer. Due to the low efficiency of these vaccines, the administration technique plays an important role in the vaccine design and its efficacy. These DNA cancer vaccine delivery systems include physical, biological, and non-biological techniques. Although the pre-clinical studies show promising results in the application of the different delivery systems, further studies in clinical trials have not yet been successfully proven.

• Journal of Korean Biological Nursing Science
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• v.6 no.1
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• pp.17-31
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• 2004

The purpose of this study was to analyze the concept of physical activity. The method was based on the steps of concept analysis by Walker and Avant(1988). The result of this study were as follows； Upon the concept analysis, physical activity is defined as a series of bodily movements which is performed voluntarily by individual. The defining attributes of physical activity were a series of bodily movements, energy expenditure, goal-directedness, and self-control of the body. The antecedents of physical activity were neuromusculoskeletal function, cardiopulmonary function and cognitive function. And the consequences of physical activity were improvement of physical function, induction of fatigue, and need(physiopsychosocial) satisfaction. Further studies are needed to develop the concept of physical activity using the Hybrid model. In addition, considering personal characteristics it is important to study the facilitating factors of physical activity.

• Journal of Korean Biological Nursing Science
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• v.19 no.4
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• pp.227-240
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• 2017

Purpose: The purpose of this review was to identify the current status of nursing studies on heart failure (HF) patients in South Korea and to suggest future study direction. Methods: A literature review of databases such as KoreaMed, KERIS and nursing and allied health journal were searched with key terms 'heart failure' and 'nursing' for the period from January 2000 to February 2017. A total of 35 studies including 28 articles and 7 theses met the inclusion criteria. Results: Twenty-seven out of 35 studies were observational studies on outpatients and most of the studies did not mention the ejection fraction and New York Heart Association functional classification class (NYHA class) in the inclusion criteria. Self-care and health-related quality of life as psychological factors, and physical activity as a biological factor, were used as main variables. However, we found it difficult to understand how much score indicates better quality of life because of an inconsistent and wide score. In quality assessment, 8 intervention studies had no serious flaws. Conclusion: Further studies should consider more biological and social factors influencing HF. The quality assessment with respect to nursing intervention studies in HF showed that randomized and double-blind trials are needed.

• Korean Journal of Exercise Nutrition
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• v.24 no.3
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• pp.25-31
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• 2020

[Purpose] Epidemiological evidence has shown that leisure-time physical activity and structured exercise before and after breast cancer diagnosis contribute to reducing the risk of breast cancer recurrence and mortality. Thus, in this review, we aimed to summarize the physical activity-dependent regulation of systemic factors to understand the biological and molecular mechanisms involved in the initiation, progression, and survival of breast cancer. [Methods] We systematically reviewed the studies on 1) the relationship between physical activity and the risk of breast cancer, and 2) various systemic factors induced by physical activity and exercise that are potentially linked to breast cancer outcomes. To perform this literature review, PubMed database was searched using the terms "Physical activity OR exercise" and "breast cancer", until August 5th, 2020; then, we reviewed those articles related to biological mechanisms after examining the resulting search list. [Results] There is strong evidence that physical activity reduces the risk of breast cancer, and the protective effect of physical activity on breast cancer has been achieved by long-term regulation of various circulatory factors, such as sex hormones, metabolic hormones, inflammatory factors, adipokines, and myokines. In addition, physical activity substantially alters wholebody homeostasis by affecting numerous other factors, including plasma metabolites, reactive oxygen species, and microRNAs as well as exosomes and gut microbiota profile, and thereby every cell and organ in the whole body might be ultimately affected by the biological perturbation induced by physical activity and exercise. [Conclusion] The understanding of integrative mechanisms will enhance how physical activity can ultimately influence the risk and prognosis of various cancers, including breast cancer. Furthermore, physical activity could be considered an efficacious non-pharmacological therapy, and the promotion of physical activity is probably an effective strategy in primary cancer prevention.

• Journal of the Korean Institute of Landscape Architecture
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• v.28 no.2
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• pp.49-60
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• 2000

The purpose of this study is to overview domestic and foreign trends in the study of the landscape evaluation through new framework of landscape evaluation studies. 108 studies on the landscape evaluation are summarized and categorized into theoretical studies, verification of theories, development of evaluation methods and applications in physical planning. Major theories in the landscape evaluation came from the psycho-physics, the evolutionary theory ann the cultural-learning theory, and were verified and applied into physical planning. Early experimental researches on landscape evaluation, based on psycho-physics, were focused on relatively simple responses to landscapes. But many studies have been gradually related to the evolutionary theory and the cultural learning theory, emphasizing biological and cultural effects on landscape evaluation. Especially, Appleton's Prospect-Refuge theory' and Kaplans' 'Information Processing model' have very strong influence in landscape evaluation. Relatively there have been many application researches in Korea, which tells there have been strong needs to solve pending practical problems caused by the rapid economic and social growth for several decades. Almost of applications in physical planning are focused on physical features of landscapes, but for more comprehensive landscape evaluation, many other factors such as cognitive and sociocultural variables should be integrated into the whole evaluation system. As a result of reviewing of landscape evaluation studies, I found the overall domestic and foreign trends and the necessity of more research on the applications in physical planning. Because this study mainly focused on academic researches, for more appropriate landscape evaluation and management there should be more practical researches including various approaches.

• Korean Journal of Exercise Nutrition
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• v.24 no.4
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• pp.1-6
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• 2020

[Purpose] Exercise is a fundamental way to maintain and improve health and physical fitness. Many human studies have demonstrated the beneficial effects of exercise on various biological parameters. However, studies investigating the effects of exercise in dogs are limited. This review summarized the current data from studies that examined the effects of different exercise conditions (treadmill vs. non-treadmill and acute vs. chronic) on physiological and hematological parameters in dogs. [Methods] Papers addressing the effects of exercise in dogs published from January 2000 to October 2020 were retrieved from the online databases of Scopus, Google Scholar, and PubMed and were selected and reviewed. [Results] The exercise conditions differentially affected physiological and hematological responses and adaptation in dogs. Therefore, the development and comprehensive evaluation of scientific exercise programs for dogs are necessary. [Conclusion] The dog would be a valuable exercise science animal model, and studies aiming at the optimal health, well-being, and quality of life of dogs need to be conducted.

• Journal of Korean Biological Nursing Science
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• v.21 no.3
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• pp.161-168
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• 2019

Purpose: The purpose of this paper (a literature review study) was to confirm the trend of nursing research for head and neck cancer patients in Korea. Methods: Research databases were reviewed and analyzed from 13 papers (2004 through 2019 using KISS, NDSL, RISS, DBpia, and the National Assembly Library. As a result of this paper, we found that there were many studies that used questionnaires. Results: Measurement variables related to head and neck cancer patients were physical variables related to oral condition, psychological variables related to depression and anxiety, social support, family support related to family, and quality of life as a result variable. Conclusion: Therefore, integrated nursing intervention strategies and clinical nursing research considering the physical, psychological, social, and family aspects of head and neck cancer patients are needed. Based on the results of this study, we propose qualitative research on head and neck cancer patients, development of educational programs, intervention studies to verify effects, and development of clinical practice guidelines.