• Progress in Medical Physics
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• v.28 no.4
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• pp.226-231
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• 2017

The aim is to investigate the spectra responsibilities of QD (Quantum Dot) for the innovation of new dosimetry application for therapeutic Megavoltage X-ray range. The unique electrical and optical properties of QD are expected to make it a good sensing material for dosimeter. This study shows the spectra responsibility of toluene based ZnCd QD and PPO (2.5-diphenyloxazol) mixed liquid scintillator. The QDs of 4 sizes corresponding to an emission wavelength (ZnCdSe/ZnS:$440{\pm}5nm$, ZnCdSeS:470, 500, $570{\pm}5nm$) were utilized. A liquid scintillator for control sample was made of toluene, PPO. The Composition of QD loaded scintillators are about 99 wt% Toluene as solvent, 1 wt% of PPO as primary scintillator and 0.05, 0.1, 0.2 and 0.4 wt% of QDs as solute. For the spectra responsibility of QD scintillation, they were irradiated for 30 second with 6 MV beam from a LINAC ($Infinity^{TM}$, Elekta). With the guidance of 1.0 mm core diameter optical fiber, scintillation spectrums were measured by a compact CCD spectrometer which could measure 200~1,000 nm wavelength range (CCS200, Thorlabs). We measured the spectra responsibilities of QD loaded organic liquid scintillators in two scintillation mechanisms. First was the direct transfer and second was using wave shifter. The emission peaks from the direct transfer were measured to be much smaller luminescent intensity than based on the wavelength shift from the PPO to QDs. The emission peak was shifted from PPO emission wavelength 380 nm to each emission wavelength of loaded QD. In both mechanisms, 500 nm QD loaded samples were observed to radiate in the highest luminescence intensity. We observed the spectra responsibility of QD doped toluene based liquid scintillator in order to innovate QD dosimetry applicator. The liquid scintillator loading 0.2 wt% of 500 nm emission wavelength QD has most superior responsibility at 6 MV photon beam. In this study we observed the spectra responsibilities for therapeutic X-ray range. It would be the first step of innovating new radiation dosimetric methods for radiation treatment.

• Progress in Medical Physics
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• v.14 no.4
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• pp.240-248
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• 2003

The Monte Carlo calculation is the most accurate means of predicting radiation dose, but its accuracy is accompanied by an increase in the amount of time required to produce a statistically meaningful dose distribution. In this study, the effects on calculation time by introducing variance reduction techniques and increasing computing power, respectively, in the Monte Carlo dose calculation for a 6 MV photon beam from the Varian 600 C/D were estimated when maintaining accuracy of the Monte Carlo calculation results. The EGSnrc­based BEAMnrc code was used to simulate the beam and the EGSnrc­based DOSXYZnrc code to calculate dose distributions. Variance reduction techniques in the codes were used to describe reduced­physics, and a computer cluster consisting of ten PCs was built to execute parallel computing. As a result, time was more reduced by the use of variance reduction techniques than that by the increase of computing power. Because the use of the Monte Carlo dose calculation in clinical practice is yet limited by reducing the computational time only through improvements in computing power, introduction of reduced­physics into the Monte Carlo calculation is inevitable at this point. Therefore, a more active investigation of existing or new reduced­physics approaches is required.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7785-7788
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• 2015

Utilization of high energy photons (>10MV) with an optimal weight using a mixed energy technique is a practical way to generate a homogenous dose distribution while maintaining adequate target coverage in intact breast radiotherapy. This study represents a model for estimation of this optimal weight for day to day clinical usage. For this purpose, treatment planning computed tomography scans of thirty-three consecutive early stage breast cancer patients following breast conservation surgery were analyzed. After delineation of the breast clinical target volume (CTV) and placing opposed wedge paired isocenteric tangential portals, dosimeteric calculations were conducted and dose volume histograms (DVHs) were generated, first with pure 6MV photons and then these calculations were repeated ten times with incorporating 18MV photons (ten percent increase in weight per step) in each individual patient. For each calculation two indexes including maximum dose in the breast CTV ($D_{max}$) and the volume of CTV which covered with 95% Isodose line ($V_{CTV,95%IDL}$) were measured according to the DVH data and then normalized values were plotted in a graph. The optimal weight of 18MV photons was defined as the intersection point of $D_{max}$ and $V_{CTV,95%IDL}$ graphs. For creating a model to predict this optimal weight multiple linear regression analysis was used based on some of the breast and tangential field parameters. The best fitting model for prediction of 18MV photons optimal weight in breast radiotherapy using mixed energy technique, incorporated chest wall separation plus central lung distance (Adjusted R2=0.776). In conclusion, this study represents a model for the estimation of optimal beam weighting in breast radiotherapy using mixed photon energy technique for routine day to day clinical usage.

• Korean Journal of Food Science and Technology
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• v.49 no.3
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• pp.252-257
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• 2017

In this study, the physicochemical properties of irradiated (gamma-ray and electron-beam) soybeans with different processing (dry and powder) and origins (Korea, China, and USA) were investigated and compared. The results of photostimulated luminescence (PSL) screening indicated that all non-irradiated soybeans showed photon counts (PCs) ${\leq}700$, while all irradiated soybeans showed positive values-gamma-ray 5,815-39,591 count/min; electron beam 5,791-60,055 count/min. The results of thermoluminescence (TL) analysis of all irradiated soybeans indicated that the $TL_1$ glow curves exhibited maximum peaks at 150-250. TL ratio of irradiated samples was ${\geq}0.1$; therefore, the clear identification of irradiated samples was guaranteed by analysis of the $TL_1$ curve shape and TL ratios. The results of electron spin resonance (ESR) signal of 3 irradiated and dried soybeans showed two side peaks mutually spaced at 6.0 mT (cellulose radical). Non-specific signal was detected for all irradiated soybean powders; hence, ESR analysis could not be performed.

• Progress in Medical Physics
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• v.18 no.2
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• pp.93-97
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• 2007

This study was designed to evaluate radiosurgery technique using multiple noncoplanar arc therapy with intensity modulated fine MLC shaped photon beam. The stereotactic radiosurgery was performed with 6-MV X-ray beams from a Clinac 21EX LINAC (Varian, Palo Alto, CA, USA) with a MLC-120, which features a full $40{\times}40cm$ field and is the first MLC for general use that offers 0.5 cm resolution for high precision treatment of small and irregular fields. We used a single isocenter and five gantry-couch combinations with a set of intensity modulated arc therapy. We investigated dosimetric characteristics of 2 cm sized spherical target volume with film (X-OMAT V2 film, Kodak Inc, Rochester NY, USA) dosimetry within $25{\times}25cm$ acrylic phantom. A simulated single isocentric treatment using inversely Planned 3D radiotherapy planning system demonstrated the ability to conform the dose distribution to an spherical target volume. The 80% dose level was adequate to encompass the target volume in frontal, sagittal, and transverse planes, and the region between the 40% and 80% isodose lines was $4.0{\sim}4.5mm$ and comparable to the dose distribution of the Boston Arcs. We expect that our radiosurgery technique could be a treatment option for irregular-shaped large intracranial target.

• Progress in Medical Physics
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• v.15 no.4
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• pp.186-191
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• 2004

The periodic Quality Assurance (QA) of each radiation treatment related equipments is important one, but quality assurance of the radiation treatment planning system (RTPS) is still not sufficient rather than other related equipments in clinics. Therefore, this study will present and test the periodic QA program to compare, evaluation the efficiency of the treatment planning systems. This QA program is divided to terms for the input, output devices and dosimetric data and categorized to the weekly, monthly, yearly and non-periodically with respect to the job time, frequency of error, priority of importance. CT images of the water equivalent solid phantom with a heterogeneity condition are input into the RTPS to proceed the test. The actual measurement data are obtained by using the ion chamber for the 6 MV, 10 MV photon beam, then compared a calculation data with a measurement data to evaluate the accuracy of the RTPS. Most of results for the accuracy of geometry and beam data are agreed within the error criteria which is recommended from the various advanced country and related societies. This result can be applied to the periodic QA program to improve the treatment outcome as a proper model in Korea and used to evaluate the accuracy of the RTPS.

• The Korean Journal of Food & Health Convergence
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• v.4 no.1
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• pp.15-22
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• 2018

A radiation dosimeter is important to assess quality assurance (QA) of radiation therapy devices and to estimate the radiation dose in vivo dosimetry. Recently, optically stimulated luminescence detector (OSLD) is widely used in clinical filed. Therefore, the purpose of this study is to evaluate dose, energy, and angular dependence of OSLD and EBT3 film. The absorbed dose in clinical linear accelerator (Linac) beam is calibrated for dose per monitor unit (MU). Dose, energy, and angular dependence of OSLD and EBT3 film are estimated after the calibration procedure. The absorbed dose is measured at 50, 100, 150, and 200 cGy in an 6 MV X-ray beam for dose dependence. A dose of 150 cGy is delivered to OSLD and EBT3 film with 6 and 10 MV photon energies for energy dependence. For measurements of angular dependence, angular positions of gantry are $0^{\circ}{\pm}80^{\circ}$ with 6 MV at 150 cGy. The results of dose dependence is linear for OSLD and EBT3 film. For the results of energy dependence, errors were 0.39% and 0.03% for OSLD and EBT3 film, respectively. The results of dose for angular is decreased from $0^{\circ}$ to ${\pm}80^{\circ}$ for both OSLD and EBT3 film. When angle of $0^{\circ}$ is normalized to 1, and the dose is decreased to 60 and 66% at $80^{\circ}$ for OSLD and EBT3 film, respectively. Dose and energy dependence of OSLD and EBT3 film are measured within the recommendation of manufacturer. Angular dependence is increased from $0^{\circ}$ to ${\pm}80^{\circ}$ for OSLD and EBT3 film. The characteristics of OSLD and EBT3 film are similar and expected to useful for clinical field.

• Journal of radiological science and technology
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• v.24 no.2
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• pp.49-52
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• 2001

We compared the characteristics of Siemens virtual wedge device with physical wedges for clinical application. We investigated the characteristics of virtual and physical wedges for various wedge angles (15, 30, 45, and 60) using 6- and 15-MV photon beams. Wedge factors were measured in water using an ion chamber for various field sizes and depths. In case of virtual wedge device, as upper jaw moves during irradiation, wedge angles were estimated by accumulated doses. These measurements were performed at off-axis points perpendicular to the beam central axis in water for a $15\;cm\;{\times}\;20\;cm$ radiation field size at the depth of 10 cm. Surface doses without and with virtual or physical wedges were measured using a parallel plate ion chamber at surface. Field size was $15\;cm\;{\times}\;20\;cm$ and a polystyrene phantom was used. For various field sizes, virtual and physical wedge factors were changed by maximum 2.1% and 3.9%, respectively. For various depths, virtual and physical wedge factors were changed by maximum 1.9% and 2.9%, respectively. No major difference was found between the virtual and physical wedge angles and the difference was within 0.5. Surface dose with physical wedge was reduced by maximum 20% (x-ray beam : 6 MV, wedge angle : 45, SSD : 80 cm) relative to one with virtual wedge or without wedge. Comparison of the characteristics of Siemens virtual wedge device with physical wedges was performed. Depth dependence of virtual wedge factor was smaller than that of physical wedge factor. Virtual and physical wedge factors were nearly independent of field sizes. The accuracy of virtual and physical wedge angles was excellent. Surface dose was found to be reduced using a physical wedge.

• Journal of the Korean Society of Radiology
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• v.15 no.2
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• pp.239-246
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• 2021

Portal Dosimetry was verified using EPID to secure the clinical application and reliability of the existing research dose evaluation. The dose distribution of Geant4 was compared with the measured value by 360° rotational irradiation with a 2.5 cm cone for stereotactic brain surgery. To confirm the dose distribution of patients with brain metastasis, the dose distribution investigated by inserting a Gafchromic EBT film into the parietal phantom and the dose distribution obtained from the parietal phantom using VMAT are compared and applied to actual patients. As a result of the analysis, it was confirmed that the accuracy of the beam center and the center of the couch coincide accurately with an error within 1mm as a result of QA through a pin ball. In addition, it was confirmed that the EBT3 film has excellent linearity in the range of 0 to 10 Gy according to various dose irradiation. In the same setting as the two cervical phantoms, we confirm that the implementation and simulation results calculations of dose calculations based on Geant4 using photon beams match the experimental data within the treatment planning volume (PTV). Therefore, volume modulated arc treatment (VMAT) 360° rotational irradiation was performed, and the result of iso-dose distribution analysis by rotational irradiation confirmed that it is appropriate to include a virtual tumor.

• Journal of the Korean Society of Radiology
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• v.12 no.7
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• pp.909-917
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• 2018

3D printing technology is expected to be an innovative technology of the manufacturing industry during the 4th industrial revolution, and it is being used in various fields including biotechnology and medical field. In this study, we verified the printing materials through Monte Carlo simulation to evaluate the radiation shielding ability of the raw material using this 3D printing technology. In this paper, the printing materials were selected from the raw materials available in a general-purpose FDM-based 3D printer. Simulation of the ICRU phantom and the shielding system was carried out to evaluate the shielding effect by evaluating the particle fluence according to the type and energy of radiation. As a result, the shielding effect tended to decrease gradually with increasing energy in the case of photon beam, and the shielding effect of TPU, PLA, PVA, Nylon and ABS gradually decreased in order of materials. In the case of the neutron beam, the neutron intensity increases at a low thickness of 5 ~ 10 mm. However, the effective shielding effect is shown above a certain thickness. The shielding effect of printing material is gradually increased in the order of Nylon, PVA, ABS, PLA and TPU Respectively.