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http://dx.doi.org/10.7742/jksr.2021.15.2.239

Comparison of Linac-based VMAT Stereotatic Radiosurgery and Conventional Stereotatic Radiosurgery for Multiple Brain Lesions  

Jang, Eun-Sung (Department of Radiation Oncology Kosin University Gospel Hospital)
Chang, Bo-Seok (Department of Radiological Science, Gin Cheon University)
Publication Information
Journal of the Korean Society of Radiology / v.15, no.2, 2021 , pp. 239-246 More about this Journal
Abstract
Portal Dosimetry was verified using EPID to secure the clinical application and reliability of the existing research dose evaluation. The dose distribution of Geant4 was compared with the measured value by 360° rotational irradiation with a 2.5 cm cone for stereotactic brain surgery. To confirm the dose distribution of patients with brain metastasis, the dose distribution investigated by inserting a Gafchromic EBT film into the parietal phantom and the dose distribution obtained from the parietal phantom using VMAT are compared and applied to actual patients. As a result of the analysis, it was confirmed that the accuracy of the beam center and the center of the couch coincide accurately with an error within 1mm as a result of QA through a pin ball. In addition, it was confirmed that the EBT3 film has excellent linearity in the range of 0 to 10 Gy according to various dose irradiation. In the same setting as the two cervical phantoms, we confirm that the implementation and simulation results calculations of dose calculations based on Geant4 using photon beams match the experimental data within the treatment planning volume (PTV). Therefore, volume modulated arc treatment (VMAT) 360° rotational irradiation was performed, and the result of iso-dose distribution analysis by rotational irradiation confirmed that it is appropriate to include a virtual tumor.
Keywords
Geant4 simulation; Alderson rando phantom; SRS(stereotactic radiosurgery); dose distribution; VMAT;
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1 G. M. Clark, R. A. Popple, P. E. Young, et al., "Feasibility of single-isocenter volumetric modulated arc radiosurgery for treatment of multiple brain metastases", International Journal of Radiation Oncology Biology Physics, Vol. 76, No, 1, pp. 296-302, 2010. http://dx.doi.org/10.1016/j.ijrobp.2009.05.029   DOI
2 T. M. Peters, J. A. Clark, G. B. Pike, C. Henri, L. Collins, D. Leksell, O. Jeppsson, "Stereotactic Neurosurgery Planning on a Personal Computer Based Work Station", Journal of Digital Imaging, Vol. 2, No. 2, pp. 75-81, 1989. http://dx.doi.org/10.1007/BF03168023   DOI
3 F. Colombo, A. Benedetti, F. Pozza, A. Zanardo, R. C. Avanzo, G. Chierego, C. Marchetti, "Stereotactic radiosurgery utilizing a linear accelerator", Applied Neurophysiology, Vol. 48, pp. 133-145, 1985. http://dx.doi.org/10.1159/000101117   DOI
4 Hartmann Gunther H., Schlegel Wolfgang, Sturm Volker, Kober Bernd, Pastyr Otto, Lorenz Walter J., "Cerebral radiation surgery using moving field irradiation at a linear accelerator facility", International Journal of Radiation Oncology Biology Physics, Vol. 11, No. 6, pp. 1185-1192, 1985. http://dx.doi.org/10.1016/0360-3016(85)90068-9   DOI
5 Siddon Robert L., Barth Norman H., "Stereotaxic localization of intracranial targets", International Journal of Radiation Oncology Biology Physics, Vol. 13, No. 8, pp. 1241-1246, 1987. http://dx.doi.org/10.1016/0360-3016(87)90201-X   DOI
6 E. S. Jang, C. S. Lee, "Feasibility Study of Dose Evaluation of Stereotactic Radiosurgery using GafChromic EBT® Film", The Journal of Korean Society for Radiation Therapy, Vol. 191, No. 1, pp. 27-33, 2007.
7 G. Minniti, E. Clarke, G. Lanzetta, et al., "Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis", Radiation Oncology, Vol. 6, No. 1, pp. 48, 2011.   DOI
8 G. M. Clark, R. A. Popple, B. M. Prendergast, et al., "Plan quality and treatment planning technique for single isocenter cranial radiosurgery with volumetric modulated arc therapy", Practical Radiation Oncology, Vol. 2, No. 4, pp. 306-313, 2012. http://dx.doi.org/10.1016/j.prro.2011.12.003   DOI
9 Ramakrishna Naren, Rosca Florin, Friesen Scott, Tezcanli Evrim, Zygmanszki Piotr, Hacker Fred, "A clinical comparison of patient setup and intra-fraction motion using frame-based radiosurgery versus a frameless image-guided radiosurgery system for intracranial lesions", Radiotherapy and Oncology, Vol. 95, No. 1, pp. 109-115, 2010. http://dx.doi.org/10.1016/j.radonc.2009.12.030   DOI
10 Z. A. Kohutek, Y. Yamada, T. A. Chan, et al., "Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases", Journal of Neuro-Oncology, Vol. 125, No. 1, pp. 149-205, 2015. http://dx.doi.org/10.1007/s11060-015-1881-3   DOI
11 H. Zaidi, "Relevance of accurate Monte Carlo modeling in nuclear medical imaging", Medical Physics, Vol. 26, No. 4, pp. 574-608, 1999. https://doi.org/10.1118/1.598559   DOI
12 Sean Jy-Shyang Chen, Pierre Hellier, Maud Marchal, Jean-Yves Gauvrit, Romain Carpentier, Xavier Morandi, D. Louis Collins, "An anthropomorphic polyvinyl alcohol brain phantom based on Colin27 for use in multimodal imaging", Medical Physics, Vol. 39, No. 1, pp. 554-561, 2012. http://dx.doi.org/10.1118/1.3673069   DOI
13 B. Tas, I. F. Durmus, A. Okumus, et al., "Correlation between heterogeneity index (HI) and gradient index (GI) for high dose stereotactic radiotherapy/radiosurgery (SRT/SRS)", AIP Conference Proceedings, Vol. 1815, No. 1, 2017. https://doi.org/10.1063/1.4976462   DOI
14 F. Colombo, A. Benedetti, F. Pozza, A. Zanardo, R. C. Avanzo, G. Chierego, C. Marchetti, "Stereotactic Radiosurgery Utilizing a Linear Accelerator", Stereotactic and Functional Neurosurgery, Vol. 48, pp. 133-145, 2004. http://dx.doi.org/10.1159/000101117   DOI
15 Giuseppe Minniti, Claudia Scaringi, Enrico Clarke, Maurizio Valeriani, Mattia Osti, Riccardo Maurizi Enrici, "Frameless linac-based stereotactic radiosurgery (SRS) for brain metastases: analysis of patient repositioning using a mask fixation system and clinical outcomes", Radiation Oncology, Vol. 6, No. 1, pp. 158, 2011. http://dx.doi.org/10.1186/1748-717X-6-158   DOI
16 Stanhope C, Chang Z, Wang Z, et al. "Physics considerations for single-isocenter, volumetric modulated arc radiosurgery for treatment of multiple intracranial targets", Practical Radiation Oncology, Vol. 6, No. 3, pp. 207-213, 2016. http://dx.doi.org/10.1016/j.prro.2015.10.010   DOI
17 R. D. Lewis, S. J. Ryde, A. W. Seaby, D. A. Hancock, C. J. Evans, "Use of Monte Carlo computation in benchmarking radiotherapy treatment planning system algorithms", Physics Medicine and Biology, Vol. 45, No. 7, pp. 1755-1764, 2000. http://dx.doi.org/10.1088/0031-9155/45/7/304   DOI
18 A. Kimura, S. Tanaka, T. Aso, H. Yoshida, N. Kanematsu, M. Asai, T. Sasaki, "DICOM Interface and Visualization Tool for Geant4-based Dose Calculation", 2005 IEEE Nuclear Science Symposium Conference Record, Vol. 2, pp. 981-984, 2005. https://doi.org/10.1109/NSSMIC.2005.1596418   DOI
19 M. K. Kang, "Comparison of the Dose of the Normal Tissues among Various Conventional Techniques for Whole Brain Radiotherapy", The Korean Society for Radiation Oncology, Vol. 28, No. 2, pp. 99-105, 2010. http://dx.doi.org/10.3857/jkstro.2010.28.2.99   DOI
20 Filippo Alongi, Alba Fiorentino, Pietro Mancosu, Pierina Navarria, Niccolo Giaj Levra, Rosario Mazzola, "Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach", Expert Review of Anticancer Therapy, Vol. 16, No. 7, pp. 731-771, 2016. http://dx.doi.org/10.1080/14737140.2016.1190648   DOI
21 J. D. Graham, A. E. Nahum, M. Brada, "A comparison of techniques for stereotatic radiotherapy by linear accelerator based on 3-dimensional dose distributions", Radiotherapy and Oncology, Vol. 22, No. 1, pp. 29-35, 1991. http://dx.doi.org/10.1016/0167-8140(91)90066-P   DOI
22 D. W. Andrews, C. B. Scott, P. W. Sperduto, A. E. Flanders, L. E. Gaspar, M. C. Schell, et al., "Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial", The Lancet, Vol. 363, No. 9422, pp. 1665-1672, 2004. http://dx.doi.org/10.1016/S0140-6736(04)16250-8   DOI