• Archives of Pharmacal Research
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• 제19권6호
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• pp.562-565
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• 1996

The photoreactivity of twelve anthraquinone derivatives was examined to evaluate its usefulness as a photo-reagent for the analysis of ginsenosides using photoreduction fluorescence (PRF) detection method. Among the tested compounds, 2-tert-butylandthraquinone (TBAQ), 2-chloroanthraquinone (CAQ) and anthraquinone (AQ) showed good characteristics as photoreagents. The detection limits of ginsenoside $Rg_{1}$PRF-HPLC method using TBAQ, CAQ or AQ as a photo-reagent were found to be ca. 35 ng, 50 ng and 50 ng, respectively.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1994년도 추계학술대회 논문집
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• pp.354-359
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• 1994

On-line process control equipment for CO $_{2}$ laser cutting is unavailable for industrial application. The major part of the industrial cutting machines are regulated off-line by highly educated engineers. The quality inspection of the sample is visual and referred to different quality scales. Due to lack of automation potential laser users hesitate to implement the cutting method. The first step toward an automation of the process is development of a process monitoring system and the research is concentrated on the area of on-line quality detection during CO $_{2}$ laser cutting. The method bases on the detection of the emitted light from the cut front by photo diode. the signal from photo diode has been undertaken from Fourier analysis and statistical analysis. As a result, it is possible to estimate striation pattern according to beam travel speed.

• 한국광학회:학술대회논문집
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• 한국광학회 2002년도 하계학술발표회
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• pp.252-253
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• 2002

원적외선 영역에서 혈중성분들의 분광 특성이 존재함이 확인되면서 이 영역의 빛을 이용한 혈중 성분의 정량 분석을 통한 진단기술 개발이 활발히 진행되고 있다1). 특히 원적외선 영역에서 특정 파장에서의 반응성을 이용한 여러 방법들 중 photo-Acoustic을 이용한 방법이 여러 가지로 연구되어지고 있다. (2) 현재 수용액 상태의 혈중 성분들의 원적외선 분광 특성을 연구하였으며, 이를 이용한 혼합 성분들의 흡수 spectrum 정량-정성 분석이 가능하며, 이러한 특성을 이용하여 non-invasive로 이용 가능한 분광법을 연구 진행 중이다. (중략)

• 센서학회지
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• 제13권2호
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• pp.85-89
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• 2004

This paper represents the development of high sensitivity photo-sensor for the fluorescence detection in the integrated biological analysis system. The finger-type PIN photodiodes were fabricated as the photo-sensor, and had a high sensitivity ($I_{light}/I_{dark}$ = 8720). The interference filter consisted of $TiO_{2}$ and $SiO_{2}$ was directly deposited on the photodiodes. Deposited filter with 95.5% reflection under 532 nm and 98% transmission over 580 nm exceedingly decreased the magnitude of background signal in the detection. The PDMS micro-fluidic channels are bonded on the photodiode by $O_{2}$ plasma treatment. The detection current was proportional to two primary parameters (light intensity, concentration), and the on-chip detection system could detect fluorescence signals down to 100 nM concentration (LOD = Limit of detection of rhodamine).

• 센서학회지
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• 제21권5호
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• pp.339-344
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• 2012

This article describes a novel method for the detection of amyloid-${\beta}$($A{\beta}$) peptide that utilizes a photo-sensitive field-effect transistor (p-FET). According to a recent study, $A{\beta}$ protein has been known to play a central role in the pathogenesis of Alzheimer's disease (AD). Accordingly, we investigated the variation of photo current generated from p-FET with and without intracellular magnetic beads conjugated with $A{\beta}$ peptides, which are placed on the p-FET sensing areas. The decrease of photo current was observed due to the presence of the magnetic beads on the channel region. Moreover, a similar characteristic was shown when the Raw 264 cells take in magnetic beads treated with $A{\beta}$ peptide. This means that it is possible to simply detect a certain protein using magnetic beads and a p-FET device. Therefore, in this paper, we suggest that our method could detect tiny amounts of $A{\beta}$ for early diagnosis of AD using the p-FET devices.

• 센서학회지
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• 제15권2호
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• pp.112-119
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• 2006

Resolution of an image sensor is very significant parameter to improve. It is hard to improve the resolution of the CMOS vision chip for edge detection based on a biological retina using a resistive network because the vision chip contains additional circuits such as a resistive network and some processing circuits comparing with general image sensors such as CMOS image sensor (CIS). In this paper, we proved the problem of low resolution by separating photo-sensing and signal processing circuits. This type of vision chips occurs a problem of low operation speed because the signal processing circuits should be commonly used in a row of the photo-sensors. The low speed problem of operation was proved by using a reset decoder. A vision chip for edge detection with $128{\times}128$ pixel array has been designed and fabricated by using $0.35{\mu}m$ 2-poly 4-metal CMOS technology. The fabricated chip was integrated with optical lens as a camera system and investigated with real image. By using this chip, we could achieved sufficient edge images for real application.

• 터널과지하공간
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• 제20권3호
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• pp.207-216
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• 2010

국내에서 현재까지 개발되어 적용된 낙석감지 시스템은 주로 낙석방지망에 와이어나 광섬유, 또는 경사계를 설치하여 와이어의 장력을 측정하거나 낙석 발생에 의해 와이어 단락이나 낙석방지망의 변형 또는 기울어지는 것을 감지하여 낙석을 확인하는 시스템들이다. 이러한 방법들은 낙석방지망이 먼저 설치되어 있어야 하며 낙석이 발생하면 일반적으로 관련 센서와 와이어 등에 대하여 재정비를 해야 다시 원래의 기능을 수행할 수 있게 된다. 이러한 단점을 해결하기 위하여 본 연구에서는 장력이나 변위 측정방식이 아니라 광센서와 카메라가 설치된 구역에서 낙석 통과 여부를 비접촉 방식으로 실시간 감지가 가능하도록 하는 방법을 제시하고 이를 구현하였다. 개발된 시스템을 실내실험 및 현장 적용을 한 결과 낙석 관련 정보를 효과적으로 수집하고 분석할 수 있었다. 또한 낙석 감지 전후 획득한 2장의 사진에 대하여 lighten 또는 difference 연산을 적용할 경우 낙석의 크기와 이동 방향에 대한 개략적 평가가 가능하였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2003년도 춘계학술대회 논문집 디스플레이 광소자분야
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• pp.100-103
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• 2003

Signal detection technologies such as fluorescence, charge and electrochemical detection used in the monolithic capillary electrophoresis system to convert the biochemical reaction into the electrical signal. The fluorescence detection using photodiodes that measure fluorescence emitted from eluting molecules is widely used for the monolithic capillary electrophoresis system. In this paper, in order to fabricate a photosensor has the increased sensitivity, we investigated on the sensitivity of general type and p-i-n type diode. The p-i-n diode has higher sensitivity than photodiode. Considering these results, we fabricated p-i-n diodes on the high resistive$(4k{\Omega}{\cdot}cm)$ wafer into rectangle and finger pattern and compared internal resistance of each pattern. The internal resistance of p-i-n diode can be decreased by the application of finger pattern has parallel resistance structure from $571{\Omega}$ to $393{\Omega}$.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.377-377
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• 2007

A simplified integration process including packaging is presented, which enables the realization of the portable fluorescence detection system. A fluorescence detection microchip system consisting of an integrated PIN photodiode, an organic light emitting diode (OLED) as the light source, an interference filter, and a microchannel was developed. The on-chip fluorescence detector fabricated by poly(dimethylsiloxane) (PDMS)-based packaging had thin-film structure. A silicon-based integrated PIN photo diode combined with an optical filter removed the background noise, which was produced by an excitation source, on the same substrate. The active area of the finger-type PIN photo diode was extended to obtain a higher detection sensitivity of fluorescence. The sensitivity and the limit of detection (LOD S/N = 3) of the system were $0.198\;nA/{\mu}M$ and $10\;{\mu}M$, respectively.

• 정보화연구
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• 제10권1호
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• pp.113-122
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• 2013

본 논문에서는 영상을 3분할 기법에 맞춰 재구성함으로써 자동으로 구도를 안정적이고 세련되게 보정하는 기법을 제안한다. Saliency Map과 Image Segmentation기술을 이용하여 사진에서 피사체의 관심영역(Region Of Interest, ROI)을 구하고, 그 영역을 기준으로 3분할 기법에 맞도록 사진을 Cropping하여 구도를 보정한다. 또한, 얼굴 인식(Face Detection)기법을 활용하여 사람의 얼굴을 ROI에 추가하고 ROI에 따른 다양한 시나리오에 의하여 구도를 보정함으로써, 좀 더 자연스러운 사진을 얻는다. 실험결과를 통해 보정된 구도의 사진이 원본사진과 비교하여 자연스럽게 보정이 되었는다는 것을 알 수 있다.