• Title/Summary/Keyword: phantom study

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In-Vivo Heat Transfer Measurement using Proton Resonance Frequency Method of Magnetic Resonance Imaging (자기 공명영상 시스템의 수소원자 공명 주파수법을 이용한 생체 내 열 전달 관찰)

  • 조지연;조종운;이현용;신운재;은충기;문치웅
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.40 no.3
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    • pp.172-180
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    • 2003
  • The purpose of this study is to observe the heat transfer process in in-vivo human muscle based on Proton Resonance Frequency(PRF) method in Magnetic Resonance Imaging(MRI). MRI was obtained to measure the temperature variation according to the heat transfer in phantom and in-vivo human calf muscle. A phantom(2% agarose gel) was used in this experiment. MR temperature measurement was compared with the direct temperature measurement using a T-type thermocouple. After heating agarose gel to more than 5$0^{\circ}C$ in boiling hot water, raw data were acquired every 3 minutes during one hour cooling period for a phantom case. For human study heat was forced to deliver into volunteer's calf muscle using hot pack. Reference data were once acquired before a hot pack emits heat and raw data were acquired every 2 minutes during 30minutes. Acquired raw data were reconstructed to phase-difference images with reference image to observe the temperature change. Phase-difference of the phantom was linearly proportional to the temperature change in the range of 34.2$^{\circ}C$ and 50.2$^{\circ}C$. Temperature resolution was 0.0457 radian /$^{\circ}C$(0.0038 ppm/$^{\circ}C$) in phantom case. In vivo-case, mean phase-difference in near region from the hot pack is smaller than that in far region. Different temperature distribution was observed in proportion to a distance from heat source.

The Comparison of Motion Correction Methods in Myocardial Perfusion SPECT (심근관류 SPECT에서 움직임 보정 방법들의 비교)

  • Park, Jang-Won;Nam, Ki-Pyo;Lee, Hoon-Dong;Kim, Sung-Hwan
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.2
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    • pp.28-32
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    • 2014
  • Purpose Patient motion during myocardial perfusion SPECT can produce images that show visual artifacts and perfusion defects. This artifacts and defects remain a significant source of unsatisfactory myocardial perfusion SPECT. Motion correction has been developed as a way to correct and detect the patient motion for reducing artifacts and defects, and each motion correction uses different algorithm. We corrected simulated motion patterns with several motion correction methods and compared those images. Materials and Methods Phantom study was performed. The anthropomorphic torso phantom was made with equal counts from patient's body and simulated defect was added in myocardium phantom for to observe the change in defect. Vertical motion was intentionally generated by moving phantom downward in a returning pattern and in a non-returning pattern throughout the acquisition. In addition, Lateral motion was generated by moving phantom upward in a returning pattern and in a non-returning pattern. The simulated motion patterns were detected and corrected similarly to no-motion pattern image and QPS score, after Motion Detection and Correction Method (MDC), stasis, Hopkins method were applied. Results In phantom study, Changes of perfusion defect were shown in the anterior wall by the simulated phantom motions, and inferior wall's defect was found in some situations. The changes derived from motion were corrected by motion correction methods, but Hopkins and Stasis method showed visual artifact, and this visual artifact did not affect to perfusion score. Conclusion It was confirmed that motion correction method is possible to reduce the motion artifact and artifactual perfusion defect, through the apply on the phantom tests. Motion Detection and Correction Method (MDC) performed better than other method with polar map image and perfusion score result.

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Evaluation of the signal intensity of magnetic resonance angiography in accordance with the dilution rate of the contrast agent (조영제 희석률에 따른 조영증강 자기공명혈관조영검사의 신호강도 평가)

  • Choi, Kwan-Woo;Seo, Sung-Mi;Son, Soon-Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.8
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    • pp.5124-5130
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    • 2014
  • Dilution of the contrast agent by analyzing the change in the signal intensity during MR angiography in accordance with the viscosity and osmotic pressure minimizes the side effects, and improves the image quality. The contrast agent molarity changes by the dilution of the contrast agent in the blood, as it is injected, which leads to a change in signal intensity. Based on this principle, a phantom was prepared and experiments were performed. After the phantom experiment, a clinical experiment was conducted using the results of the phantom experiment. From November 2013 to January 2014, a group of patients were classified into diluted contrast agent (30 persons) and undiluted (30 persons), and the signal intensity of the cerebral vessels was compared. The signal intensity of the phantom according to the molarity of the contrast agent increased sharply from 0.0125 mmol, reached a peak at 20 mmol, and achieved equilibrium from 200 mmol. Based on the study results, the signal intensity of the blood vessels in the brain through were compared in a clinical experiment. All the brain vessels in the imaging range with diluting a high content of the gadolinium contrast agent showed high signal intensity. This result supports the phantom experiment and means that using the 500mmol diluted contrast agent is better than using 1000mmol undiluted contrast agent because it is easier to approach the 20mmol level needed to achieve the highest signal intensity. This study has significance in that it can minimize the high viscosity and osmotic pressure, which can cause side effects and improve the image quality using the method of the dilution rate.

Quantitative Feasibility Evaluation of 11C-Methionine Positron Emission Tomography Images in Gamma Knife Radiosurgery : Phantom-Based Study and Clinical Application

  • Lim, Sa-Hoe;Jung, Tae-Young;Jung, Shin;Kim, In-Young;Moon, Kyung-Sub;Kwon, Seong-Young;Jang, Woo-Youl
    • Journal of Korean Neurosurgical Society
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    • v.62 no.4
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    • pp.476-486
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    • 2019
  • Objective : The functional information of $^{11}C$-methionine positron emission tomography (MET-PET) images can be applied for Gamma knife radiosurgery (GKR) and its image quality may affect defining the tumor. This study conducted the phantom-based evaluation for geometric accuracy and functional characteristic of diagnostic MET-PET image co-registered with stereotactic image in Leksell $GammaPlan^{(R)}$ (LGP) and also investigated clinical application of these images in metastatic brain tumors. Methods : Two types of cylindrical acrylic phantoms fabricated in-house were used for this study : the phantom with an array-shaped axial rod insert and the phantom with different sized tube indicators. The phantoms were mounted on the stereotactic frame and scanned using computed tomography (CT), magnetic resonance imaging (MRI), and PET system. Three-dimensional coordinate values on co-registered MET-PET images were compared with those on stereotactic CT image in LGP. MET uptake values of different sized indicators inside phantom were evaluated. We also evaluated the CT and MRI co-registered stereotactic MET-PET images with MR-enhancing volume and PET-metabolic tumor volume (MTV) in 14 metastatic brain tumors. Results : Imaging distortion of MET-PET was maintained stable at less than approximately 3% on mean value. There was no statistical difference in the geometric accuracy according to co-registered reference stereotactic images. In functional characteristic study for MET-PET image, the indicator on the lateral side of the phantom exhibited higher uptake than that on the medial side. This effect decreased as the size of the object increased. In 14 metastatic tumors, the median matching percentage between MR-enhancing volume and PET-MTV was 36.8% on PET/MR fusion images and 39.9% on PET/CT fusion images. Conclusion : The geometric accuracy of the diagnostic MET-PET co-registered with stereotactic MR in LGP is acceptable on phantom-based study. However, the MET-PET images could the limitations in providing exact stereotactic information in clinical study.

Beam Spoiler-dependent Total Body Irradiation Dose Assessment (전신방사선조사 시 선속 스포일러에 따른 선량 분포 및 영향 평가)

  • Lee, Dong-Yeon;Kim, Jung-Hoon
    • Journal of radiological science and technology
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    • v.41 no.2
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    • pp.141-148
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    • 2018
  • This study examined the properties of photons and the dose distribution in a human body via a simulation where the total body irradiation(TBI) is performed on a pediatric anthropomorphic phantom and a child size water phantom. Based on this, we tried to find the optimal photon beam energy and material for beam spoiler. In this study, MCNPX (Ver. 2.5.0), a simulation program based on the Monte Carlo method, was used for the photon beam analysis and TBI simulation. Several different beam spoiler materials (plexiglass, copper, lead, aluminium) were used, and three different electron beam energies were used in the simulated accelerator to produce photon beams (6, 10, and 15 MeV). Moreover, both a water phantom for calculating the depth-dependent dosage and a pediatric anthropomorphic phantom for calculating the organ dosage were used. The homogeneity of photon beam was examined in different depths for the water phantom, which shows the 20%-40% difference for each material. Next, the org an doses on pediatric anthropomorphic phantom were examined, and the results showed that the average dose for each part of the body was skin 17.7 Gy, sexual gland 15.2 Gy, digestion 13.8 Gy, liver 11.8 Gy, kidney 9.2 Gy, lungs 6.2 Gy, and brain 4.6 Gy. Moreover, as for the organ doses according to materials, the highest dose was observed in lead while the lowest was observed in plexiglass. Plexiglass in current use is considered the most suitable material, and a 6 or 10 MV photon energy plan tailored to the patient condition is considered more suitable than a higher energy plan.

Development of Radiation Restrictor for Secondary Radiation Shielding of Mobile X-ray Generator (이동형 X선 발생장치의 2차 방사선 차폐를 위한 선속조절기 개발 연구)

  • Koo, Bon-Yeoul;Kim, Gha-Jung
    • Journal of radiological science and technology
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    • v.41 no.5
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    • pp.397-403
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    • 2018
  • Mobile X-ray generators are used not in the radiation area but in open space, which causes the exposure of secondary radiation to the healthcare professionals, patients, guardians, etc., regardless of their intentions. This study aimed to investigate the shielding effect of the developed radiation restrictor to block the secondary radiation scattered during the use of mobile X-ray generator. Upon setting the condition of mobile X-ray generator with chest AP, spatial doses were measured by the existence of human equivalent phantom and radiation restrictor, and measured by the existences of phantom and radiation restrictor at the same length of 100 cm. Measurements were taken at intervals of 10 cm every $30^{\circ}$ from $-90^{\circ}$ (head direction) to $+90^{\circ}$ (body direction). Upon the study results, spatial doses in all direction were increased by 45% on average when using phantom in the same condition, however, they were decreased by 64% on average when using the developed radiation restrictor. The dose at 100 cm from the center of X-ray was $3.0{\pm}0.08{\mu}Gy$ without phantom and was increased by 40% with $4.2{\pm}0.08{\mu}Gy$ after phantom usage. The dose when using phantom and the developed radiation restrictor was $1.4{\pm}0.08{\mu}Gy$, which was decreased by 66% compared to the case without using them. Therefore, it is considered the scattered radiation can be shielded at 100-150 cm, the regulation of the distance between beds, effectively with the developed radiation restrictor when using mobile X-ray generators, which can lower the radiation exposure to the people nearby including healthcare professionals and patients.

Case Study of Quality Assurance for MDCT Image Quality Evaluation Using AAPM CT Performance Phantom (AAPM CT 성능 평가용 팬텀을 이용한 전산화단층촬영의 영상 평가를 위한 정도관리 사례 연구)

  • Jang, Keun-Jo;Kweon, Dae-Cheol
    • The Journal of the Korea Contents Association
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    • v.7 no.7
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    • pp.114-123
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    • 2007
  • The increasing use of computed tomography (CT) as a diagnostic tool creates the need from and efficient means of evaluating the performance of the CT scanner now in use. Accordingly, acceptance testing and quality assurance of CT is of great importance. The aim of this study is to analyze of AAPM CT performance phantom in the CT accreditation program. The modular phantom offers the CT system with which to measure eight performance parameters. The parameters are listed of CT attenuation coefficient of water, noise, uniformity, spatial resolution, contrast resolution, slice thickness (5 and 10 mm), artifacts and alignment. The phantom evaluation was done by two radiologists. The acceptance testing protocol described here in demonstrates the successful of the guidelines for the quality assurance using AAPM CT performance phantom. We need to be upgraded for the CT image quality and make the standard reference of the quality assurance in the CT.

Characteristic Changes Observation of N-isopropylacrylamide Phantom by Repeated Ultrasound Irradiation (초음파 반복 조사에 따른 NIPAM 팬텀의 특성 변화 관찰)

  • Kim, Ju-Young;Kim, Jae-Young;Noh, Si-Cheol;Choi, Heung-Ho
    • Journal of the Korean Society of Radiology
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    • v.9 no.7
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    • pp.509-513
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    • 2015
  • In this study, we evaluated the thermal denaturation characteristics of reusable NIPAM tissue mimicking (TM) Phantom by measuring the thermal sensitivity. And the changes of acoustic characteristic and thermal denaturation shape in NIPAM TM phantom according to the number of re-use time and re-use period were observed. With the result, as the sonication time is increased, the sound velocity of NIPAM phantom was decreased by 100 m/s and the attenuation was increased slightly. However, the changes according to the re-use period was not observed. In the thermal denaturation shape and size observation by ultrasound sonicaton, the remarkable changes have not been confirmed. With the result of this study, NIPAM Phantom was considered appropriate to evaluate and predict the effect of therapeutic ultrasound by in repeated sonication test.

Evaluation of the Resolution Characteristics by Using ATS 535H Phantom for Ultrasound Medical Imaging (초음파 의료영상에서 ATS 535H 팬텀을 이용한 해상력 특성 평가)

  • Jung-Whan, Min;Hoi-Woun, Jeong;Hea-Kyung, Kang
    • Journal of radiological science and technology
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    • v.46 no.1
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    • pp.15-21
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    • 2023
  • This study was purpose to assessment of the resolution characteristics by using ATS 535H Basic quality assurance (QA) phantom for ultrasound. The ultrasound equipment was used Logiq P6 (Ultrasound, GE Healthcare System, Chicago, IL, USA). And the ultrasound transducer were used Convex 4C (4~5.5 MHz), Linear 11L (10~13 MHz), Sector 3SP (3~5.5 MHz) probe. As for the noise power spectrum (NPS) comparison results by using ATS 535H Basic QA ultrasound phantom and Convex 4C, Linear 11L, Sector 3SP probe. The NPS value of the Convex 4C probe image was 0.0049, Linear 11L probe image was 0.0049, Sector 3SP probe image was 0.1422 when the frequency is 1.0 mm-1. The modulation transfer function (MTF) comparison results by using ATS 535H Basic QA ultrasound phantom and Linear 11L probe the MTF value of the 3 cm focus image was 0.7511 and 4 cm focus image was 0.9001 when the frequency is 1.0 mm-1. This study was presented characteristics of spatial resolution a quantitative evaluation methods by using ultrasound medical images for QA of ultrasound medical QA phantom. The quality control (QC) for equipment maintenance can be efficiently used in the clinic due to the quantitative evaluation of the NPS and MTF as the standard methods. It is meaningful in that it is applied mutatis mutandis and presented the results of physical resolution characteristics of the ultrasound medical image.

Usefulness Assessment of Automatic Analysis Program for Flangeless Esser PET Phantom Images (Flangeless Esser PET Phantom 영상 자동 분석 프로그램의 유용성 평가)

  • NamGung, Chang-Kyeong;Nam, Ki-Pyo;Kim, Kyeong-Sik;Kim, Jeong-Seon;Lim, Ki-Cheon;Shin, Sang-Ki;Cho, Shee-Man;Dong, Kyung-Rae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.13 no.1
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    • pp.63-66
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    • 2009
  • Purpose: ACR (American College of Radiology) offers variable parameters to PET/CT quality control by using ACR Phantom. ACR Phantom was made to evaluate parameters which are uniformity, attenuation, scatter, contrast and resolution. Manual analysis method wasn't good for the use of QC because values of parameter were changed as it may user and it takes long time to analysis. Ki-Chun Lim, a nuclear scientist in AMC, developed program that automatically analysis values of parameter by using ACR Phantom to overcome above problems. In this study, we evaluated automatic analysis program's usability, through the comparing SUV of each method, reproducibility of SUV when repeated analysis and the time required. Materials and Methods: Using Flangeless Esser PET Phantom, the ideal ratio of 4 : 1 hot cylinder and BKG but it actually showed a ratio of 3.89 to 1 hot cylinder and BKG. SIEMENS Biograph True Point 40 was used in this study. We obtained images using ACR phantom at Fusion WB PET Scan condition (2 min/bed) and 120 kV, 100 mAs CT condition. Using True X method, 3 iterations, 14 subsets, Gaussian filter, FWHM 4 mm and Zoom Factor 1.0, $168{\times}168$ image size. We obtained Max. & Min. SUV and SUV Mean values at Cylinder (8, 12, 16, 25 mm, Air, Bone, Water, BKG) by automatic program and obtained SUV by manual method. After that, we compared manual and automatic method. we estimate the time required from opened the image data to final work sheet was completed. Results: Automatic program always showed same result and same the time required. At 8, 12, 16 and 25 m cylinder, manual method showed 6.69, 3.46, 2.59, 1.24 CV values. The larger cylinder size became, the smaller CV became. In manual method, bone, air, water's CV were over 9.9 except BKG (2.32). Obtained CV of Mean SUV showed BKG was low (0.85) and bone was high (7.52). The time required was 45 second, 882 second respectably. Conclusions: As a result of difference automatic method and manual method, automatic method showed always same result, manual method showed that the smaller hot cylinders became, the lager CV became. Hot cylinders mean region size, the smaller hot cylinder size becomes we had some trouble in doing ROI poison setting. And it means increase in variation of SUV. The Study showed the time required of automatic method was shorten then manual method.

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