• The Korean Journal of Pain
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• 제25권2호
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• pp.105-107
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• 2012

A 41-year-old male patient presented with idiopathic persistent hiccups. The hiccups did not respond to pharmacologic treatments including cisapride, omeprazole, and baclofen. Phrenic nerve block was also ineffective. However, the persistent hiccups were successfully treated with short-term positive pressure ventilation using a short-acting muscle relaxant.

• The Korean Journal of Pain
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• 제18권2호
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• pp.222-225
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• 2005

Hiccups are due to an intermittent clonic spasm of the diaphragm. In most cases, hiccups are self-limiting disease, but persistent hiccups may be related to the presence of serious underlying systemic disease. Two patients who had persistent hiccups that were not controled by conventional methods and medications were referred to the pain clinic. We administered a single oral medication of gabapentin, and then the hiccups disappeared in both cases. We concluded that gabapentin should be considered as an alternative therapy to control persistent or intractable hiccup. It could be particularly useful for those patients with solid malignancies, either alone or as an "add-on therapy" with other oral agents.

• 대한한방내과학회지
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• 제22권1호
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• pp.95-101
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• 2001

Hiccups is one of the omnipresent phenomenon occurring in everyone. Most episodes are time-limited, but, sometimes, they become intractable and protracted for a long time. In most cases, they are idiopathic. But, sometimes there are cases which have diverse kinds of underlying disorders. In this study, the author reports a case of idiopathic and persistent hiccups. He recently encountered a 64 year old male patient with intractable and persistent hiccups for over two weeks. By using the method of 8 Constitutional Acupuncture therapy and herbal medication( Hyangsapyeungwutang) regarding him as RENOTONIA. After 7days of treatment, the symptoms disappeared.

• The Korean Journal of Pain
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• 제8권1호
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• pp.131-134
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• 1995

Hiccup is characterized by a myoclonus in the diaphragm, resulting in a sudden inspiration associated with an audible closure of the glottis. The reflex arc in hiccups comprises three pars: an afferent, a central and an efferent part. The afferent portion of the neural pathway of hiccup formation is composed of the vagus nerve, the phrenic nerve, and the sympathetic chain arising from T6 to T12. The hiccup center is localised in the brain stem and the efferent limb comprises phrenic pathways. All stimuli affecting the above mentioned reflex arc may produce hiccups. The pathogenesis of persistent hiccups is not known. Hiccup can present a symptom of a subphrenic abscess or gastric distention, and metabolic alterations may also cause hiccups. Numerous treatment modalities have been tried but with questionable success. We describe a patient whose persistant hiccups was treated successfully by a cervical epidural block.

• 대한중풍순환신경학회지
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• 제23권1호
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• pp.1-12
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• 2022

Persistent hiccups persist for more than 48 hours. Those can often occur in cancer patients after chemotherapy or high dose of corticosteroids. A 52-year-old male patient undergoing Non-small cell lung cancer(NSCLC), recently suffered presistent hiccups and dyspnea. He was treated with herbal medicine for 56days and acupuncture for 9days. No side effects were observed during treatment. The severity of hiccups was measured in every hospital visit and psychometric symptoms were evaluated periodically through the Edmonton Symptom Assessment System(ESAS). The severity of hiccups and psychometric symptoms were alleviated and the effect persisted during the treatment. The patient took no other nervous system drugs in the end of the treatment. In conclusion, Korean medicine like Hyeongbangjihwang-tang and Jeongcheonhwadamgangki-tang can be effective for patients with persistent hiccups and dyspnea who cannot use alternative drugs or treatment because of other complications.

• The Korean Journal of Pain
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• 제23권3호
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• pp.198-201
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• 2010

Persistent and intractable hiccups (with respective durations of more than 48 hours and 1 month) can result in depression, fatigue, impaired sleep, dehydration, weight loss, malnutrition, and aspiration syndromes. The conventional treatments for hiccups are either non-pharmacological, pharmacological or a nerve block treatment. Pulsed radiofrequency lesioning (PRFL) has been proposed for the modulation of the excited nervous system pathway of pain as a safe and nondestructive treatment method. As placement of the electrode in close proximity to the targeted nerve is very important for the success of PRFL, ultrasound appears to be well suited for this technique. A 74-year-old man suffering from intractable hiccups that had developed after a coronary artery bypass graft and had continued for 7 years was referred to our pain clinic. He had not been treated with conventional methods or medications. We performed PRFL of the phrenic nerve guided by ultrasound and the hiccups disappeared.

• The Korean Journal of Pain
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• 제10권2호
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• pp.241-245
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• 1997

Persistent hiccup is defined as duration lasting longer than 48 hours. Reflex arc of hiccup is divided into three parts : afferent, central, efferent. Afferent portion of the neural pathway of hiccup formation is composed of vagus nerve, phrenic nerve, and sympathetic chain arising from T6 to T12. Efferent limb is phrenic nerve. Hiccup center is located in brain stem, midbrain, reticular system and hypothalamus. Persistent hiccup is very difficult to treat by conventional methods. We performed cervical epidural block of the phrenic nerve root for three patients suffering from persistent hiccup. The therapeutic effect was perfect. The mechanism of the cervical epidural block is not yet defined however it is thought to block the efferent nerve fibers and suppress the reflex arc of hiccup. We conclude cervical epidural block is relatively safe and very effective for treating persistent hiccup.

• 사상체질의학회지
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• 제22권3호
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• pp.152-159
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• 2010

1. Objectives: This study aims to report symptomatic improvement of a Soyangin persistent hiccup patient with Hyeongbangdojeoksan. 2. Methods: The patient was treated with Hyeongbangdojeok-san and acupunctural therapy. The patient's chief complaint and ordinaty symptoms were observed during the outpatient care period. 3. Results and Conclusions: In results, Soyangin patients's hiccup and ordinary symptom as well as improved. The management of the constitutional pathological syndromes by constitutional perspective than focusing on the symptoms of hiccups will provide more comfortable life and better health levels.

• Tuberculosis and Respiratory Diseases
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• 제64권1호
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• pp.39-43
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• 2008

저자 등은 종격동 림프절 비대를 동반한 비소세포폐암환자에서 발생한 지속성 딸꾹질을 경험하였기에 이에 대한 임상적 특성과 치료에 관한 문헌 고찰과 함께 보고하는 바이다.