• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.135-142
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• 2019

The purpose is to investigate correlation of periodontal disease and cardiovascular disease among those living alone and living with family by using 6th Korean National Health and Nutrition Examination Survey. According to general characteristics, cardiovascular diseases were found to be related to gender, education level of those living with family; and age and income level of elderly living alone. The oral health status, oral health patterns and cardiovascular disease distribution of both groups for the past year were examined. The relationship between cardiovascular disease and periodontal disease was related to hypertension only in the living with family. Cardiovascular disease and periodontal disease are the most common diseases so considering the two diseases together is necessary to check the health status in the future.

• The Journal of the Korean dental association
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• v.55 no.1
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• pp.22-29
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• 2017

Purpose : Preservation of the periodontal health of the treated patient requires supportive periodontal therapy for the elimination of periodontal disease. After Phase I therapy is completed, patients are placed on a schedule of periodic recall visits for maintenance care to prevent recurrence of the disease. The amount of tooth loss would be the most relevant criterion in an evaluation of the effect of periodontal treatment, but this would require studies with extremely long follow-up periods. Thus the most commonly used outcome criteria in clinical research have been clinical attachment level change, reduction of pocket depth and bleeding frequency. The purpose of this case study is to identify the effect of supportive periodontal therapy after periodontal flap surgery. Materials & Methods : Following routine hygienic phase of treatment, patients with chronic periodontitis received surgical periodontal treatment. Bleeding on probing, pocket depth and clinical attachment level were measured at baseline, pre-operation and 1 year follow up. All procedures were performed by one operator. Results : One year a total of 28 patients (58sites) to recheck remained, when conducted maintenance program after periodontal flap surgery was observed reduction of bleeding frequency, pocket depth and improvement of clinical attachment level. Conclusion : The results from this study indicate that supportive periodontal therapy after periodontal flap surgery is effective for reduction of bleeding frequency, pocket depth and gain of clinical attachment level.

• Journal of Periodontal and Implant Science
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• v.40 no.4
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• pp.153-163
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• 2010

Periodontal disease, as a polymicrobial disease, is globally endemic as well as being a global epidemic. It is the leading cause for tooth loss in the adult population and has been positively related to life-threatening systemic diseases such as atherosclerosis and diabetes. As a result, it is clear that more sophisticated therapeutic modalities need to be developed, which may include vaccines. Up to now, however, no periodontal vaccine trial has been successful in satisfying all the requirements; to prevent the colonization of a multiple pathogenic biofilm in the subgingival area, to elicit a high level of effector molecules such as immunoglobulin sufficient to opsonize and phagocytose the invading organisms, to suppress the induced alveolar bone loss, or to stimulate helper T-cell polarization that exerts cytokine functions optimal for protection against bacteria and tissue destruction. This article reviews all the vaccine trials so as to construct a more sophisticated strategy which may be relevant in the future. As an innovative strategy to circumvent these barriers, vaccine trials to stimulate antigen-specific T-cells polarized toward helper T-cells with a regulatory phenotype (Tregs, $CD_{4+}$, $CD_{25+}$, $FoxP_{3+}$) have also been introduced. Targeting not only a single pathogen, but polymicrobial organisms, and targeting not only periodontal disease, but also periodontal disease-triggered systemic disease could be a feasible goal.

• Journal of the Korea Convergence Society
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• v.10 no.7
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• pp.295-301
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• 2019

This study evaluated the relationship between drinking and smoking and periodontal disease in Korean elderly people using 2013-2015 National Health and Nutrition Survey. (OR) 1.50; 95% confidence interval [CI], 1.00-2.24) than the non - alcoholic and non - smoking groups. The odds ratios were significantly higher. The odds ratios of periodontal disease were significantly higher in the elderly who were drinking and smoking at the same time than those who did not drink or smoke at all. This study confirms that drinking and smoking are significantly related to periodontal disease. Therefore, it is necessary to strengthen drinking and smoking cessation education to maintain oral health of the elderly.

• Journal of dental hygiene science
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• v.18 no.4
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• pp.210-217
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• 2018

Periodontal disease is a chronic inflammatory disease that affects quality of life and nutrition. Several studies have demonstrated a link between periodontal disease and low bone density, and vitamin D is expected to have a beneficial effect on periodontal disease as well as on bone mineral density and anti-inflammatory effects. The purpose of this study was to identify the association between periodontal disease and vitamin D because the results are different in some studies and there is a lack of research in Korea. In this study, we conducted a multiple linear regression analysis of 8,783 subjects among 23,626 subjects who were older than 20 years of age, who had serum vitamin D levels and periodontal disease, who had three years of the National Health and Nutrition Survey that was conducted in Korea from 2012 to 2014. We examined the relationship between serum vitamin D levels and periodontal disease. Tooth loss and vitamin D levels were negatively correlated (${\beta}=-0.028$, p=0.008). In addition, the prevalence of periodontal disease was found to be higher in men younger than 50 years of age with lower vitamin D levels (Q1: 1.769 [1.125~2.782], Q2: 1.182 [0.743~1.881], Q3: 0.676 [0.400~1.881]; p=0.001). Low vitamin D levels and periodontal disease are common diseases in primary care. Vitamin D supplementation is expected to have favorable effect on periodontal disease and falls, osteoporosis, osteoarthritis, and cancer. Therefore, patients with periodontal disease may benefit from periodic vitamin D management to improve quality of life as well as to manage periodontal disease. In addition, as shown in this study, not only elderly individuals, but also men younger than 50 years of age are related to periodontal disease, so there should be interest in controlling the levels of vitamin D in adults.

• The Journal of the Korean dental association
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• v.19 no.3 s.142
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• pp.279-282
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• 1981

The authors observed the degree of alveolar bone resorption on the intraoral roentgenogram of 105 patients who were affected by periodontal disease, and following results were obtained. That is, the alveolar bone resorption due to the periodontal disease showed increased tendency as aging, and severe degree on the mandible in comparison with the maxilla, and revealed sere destruction on the area of mandibular incisors and maxillary molars.

• Journal of Korean society of Dental Hygiene
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• v.14 no.6
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• pp.795-804
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• 2014

Objectives: The purpose of the study was to investigate the relationship between the oral contraceptive pill and periodontal disease in Korean women aged from 19 to 50 years old. Methods: This study selected 1,579 women of childbearing age from 19 to 50 years old from the 5th National Health and Nutrition Survey data analysis(phase 3, 2012) taking the oral examination. The questionnaire consisted of socioeconomic demographic characteristics, health behavior, use of oral contraceptive pills, and periodontal disease. Socioeconomic demographic characteristics included age, marital status, education, monthly income, and vocation. The health behavior included obesity, stress, smoking, subjective oral health status, use of dental floss, tooth brushing, and diabetes mellitus by fasting blood sugar level. Use of oral contraceptive pills was recorded by monthly use and duration. The periodontal disease was documented by yes or no and selected as dependent variable by logistic regression analysis. Results: After revising the taking period of oral contraceptive pill for this study, there was the correlation between the prevalence of periodontal disease and odds ratio(95% CI) 1.288(1.027-1.617). Conclusions: This study will contribute to the direction of policy for an oral contraceptive pill and provide the basic data for counseling for the oral health and the side effects of oral contraceptive pills.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.8
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• pp.903-909
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• 2019

Periodontal disease is observed in many adult persons. However we has not clear know the molecular mechanism and how to treat the disease at the molecular levels. Here, we investigated the molecular differences between periodontal disease and normal controls using gene expression data. In particular, we checked whether the periodontal disease and normal tissues would be classified by machine learning algorithms using gene expression data. Moreover, we revealed the differentially expression genes and their function. As a result, we revealed that the periodontal disease and normal control samples were clearly clustered. In addition, by applying several classification algorithms, such as decision trees, random forests, support vector machines, the two samples were classified well with high accuracy, sensitivity and specificity, even though the dataset was imbalanced. Finally, we found that the genes which were related to inflammation and immune response, were usually have distinct patterns between the two classes.

• The Journal of Korean Academy of Prosthodontics
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• v.17 no.1
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• pp.79-82
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• 1979

교정경험, 보철물장착 경험, 교합조정, 상하악골절, 및 전신적 질환이 없는 Angle class I 교합을 갖는 100명(名)의 환자에 있어 1000개의 치아를 임상적으로 평가하여, 그 disclusion pattern과 periodontal disease index와의 상호관계를 조사해 본 결과, 14%가canine protection을 하고, 16%가 progressive disclusion을 하며, 46%가 group function을 하고 나머지 24%가 각각 바른 disclusion pattern을 띤다는 것을 알았다. 여기서 C.P.하는 mouth의 치아가 다른 3group보다도 더 낮은 periodontal disease index를 갖는다는 사실이 유의성 있는 통계자료로써 나타났다.

• Journal of Periodontal and Implant Science
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• v.43 no.3
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• pp.143-143
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• 2013