• Title/Summary/Keyword: period two solutions

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EVIDENCE OF SUSTAINED RELEASE OF CHLORHEXIDINE ADDED TO ACRYLIC RESIN : PRELIMINARY INVESTIGATION OF A POTENTIAL DRUG DELIVERY SYSTEM (아크릴릭 레진에 혼합된 클로르헥시딘의 방출 : 새로운 방법의 약물송달시스템을 위한 예비실험)

  • Choi, Yeong-Chul;Lee, Eun-Yeong;Lee, Jin-Yong
    • Journal of the korean academy of Pediatric Dentistry
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    • v.25 no.2
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    • pp.259-267
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    • 1998
  • For more than two decades, many investigators have tried a variety of methods for delivering antimicrobial agents to the oral cavity with the objective of eliminating mutans streptococci. In the belief that the effectiveness of chemotherapy might be improved by a more effective delivery system, the intention of the present study was to exploit a new drug delivery system delivering chlorhexidine to the oral cavity. The vehicle delivering chlorhexidine tested in this study was self-curing acrylic resin(polymethyl methacrylate). The powder of the acrylic resin was polymerized with the 5 different liquid preparations, in which $Chlorzoin^{(R)}$ was mixed with five different monomer/Chlorzoin ratios immediately prior to the polymerization, in a stainless steel mold ($40mm{\times}40mm{\times}2mm$). A total of 50 cured resin specimens were divided into 5 groups according to the different monomer preparations. Every specimen was soaked in an airtight container filled with distilled water (100 ml) and then kept in an incubator at $37^{\circ}C$. The solutions (0.8 ml) were collected from the container at every 24 hours, and the amount of released chlorhexidine in the solutions was measured in an ultraviolet spectrophotometer at 250nm. The container was refilled with distilled water every after measurement. This procedure was repeated for 14 days. It was found that chlorhexidine was continuously released from all of the 50 specimens during the experimental period. And it was noted that the pattern of chlorhexidine release was a type of sustained-release preparation, that is, the amount of the released chlorhexidine at the first day in all 5 groups was high (p<0.0001), and then the release was decreased during the rest of the experimental period (p<0.001).

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Effects of Coagulants and Soaking Solutions of Tofu (Soybean Curd) on Extending its Shelf Life (두부의 저장에 미치는 응고제와 침지액의 효과)

  • Lee, Kap-Sang;Kim, Dong-Han;Baek, Seung-Hwa;Choun, Seung-Ho
    • Korean Journal of Food Science and Technology
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    • v.22 no.2
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    • pp.116-122
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    • 1990
  • In order to improve the shelf life of Tofu, the effect of calcium chloride or acetic acid as coagulants were investigated for microbial and physicochemical changes during the storage in different kinds of soaking solution. The soaking water of Tofu prepared from calcium chloride was found to be spoiled after 15-17 hours of storage at $30^{\circ}C$, by reaching the bacteria count to 10million per ml. The shelf life of the Tofu prepared from acetic acid was better than those prepared by calcium chloride. For the effect of soaking solution on storage life, soaking Tofu in 0.1% acetic acid was found to be more effective than soaking in other solutions of 3% NaCl or 0.1% K-sorbate. The optical density of soaking solution of Tofu increased in proportion to spoilage, and in case of soaked Tofu in 3% sodium chloride and 0.1% K-sorbate solution, it greatly increased. Titratable acidity, and amino nitrogen contents in soaking solution increased as spoilage of Tofu progressed, but pH decreased the early period, one or two days, of stored Tofu and then increased.

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Analysis of the shelf life of chitosan stored in different types of packaging, using colorimetry and dentin microhardness

  • da Cruz-Filho, Antonio Miranda;de Vito, Angelo Rafael;Souza-Flamini, Luis Eduardo;da Costa Guedes, Debora Fernandes;Saquy, Paulo Cesar;Silva, Ricardo Gariba;Pecora, Jesus Djalma
    • Restorative Dentistry and Endodontics
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    • v.42 no.2
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    • pp.87-94
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    • 2017
  • Objectives: Chitosan has been widely investigated and used. However, the literature does not refer to the shelf life of this solution. This study evaluated, through the colorimetric titration technique and an analysis of dentin micro-hardness, the shelf life of 0.2% chitosan solution. Materials and Methods: Thirty human canines were sectioned, and specimens were obtained from the second and third slices, from cemento-enamel junction to the apex. A 0.2% chitosan solution was prepared and distributed in 3 identical glass bottles (v1, v2, and v3) and 3 plastic bottles (p1, p2, and p3). At 0, 7, 15, 30, 45, 60, 90, 120, 150, and 180 days, the specimens were immersed in each solution for 5 minutes (n = 3 each). The chelating effect of the solution was assessed by micro-hardness and colorimetric analysis of the dentin specimens. 17% EDTA and distilled water were used as controls. Data were analyzed statistically by two-way and Tukey-Kramer multiple comparison (${\alpha}=0.05$). Results: There was no statistically significant difference among the solutions with respect to the study time (p = 0.113) and micro-hardness/time interaction (p = 0.329). Chitosan solutions and EDTA reduced the micro-hardness in a similar manner and differed significantly from the control group (p < 0.001). Chitosan solutions chelated calcium ions throughout the entire experiment. Conclusions: Regardless of the storage form, chitosan demonstrates a chelating property for a minimum period of 6 months.

Two-Phase Two-Component Loop Thermosyphon with Nanofluid (나노유체를 이용한 2상유동 2성분 루프형 열사이폰)

  • Rhi Seok-Ho;Park Jong-Chan;Cha Kyeong-Il;Lim Taek-Kyu;Lee Chung-Gu;Shin Dong-Ryun;Park Gi-Ho
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.18 no.5
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    • pp.384-392
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    • 2006
  • Reported are the heat transfer characteristics of a two-phase loop thermosyphon (TLT) with nanofluids consisted of nano-size silver particles and distilled water as the working fluid. The nanofluids used in the present study are dispersed solutions with various amount of silver nanoparticle in distilled water. It is seen from the present study that the heat transfer performance of the test TLT with nanofluids increased as much as about 2 times higher than that of a TLT with pure water as the working fluid based on same heat flux. The study also showed that there was no deterioration of the TLT performance with time, up to a period of 8 days of continuous operation which implies that there was no coagulation of nanoparticles within the working nanofluid during the operation of the test TLT.

GPS/RTS data fusion to overcome signal deficiencies in certain bridge dynamic monitoring projects

  • Moschas, Fanis;Psimoulis, Panos A.;Stiros, Stathis C.
    • Smart Structures and Systems
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    • v.12 no.3_4
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    • pp.251-269
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    • 2013
  • Measurement of deflections of certain bridges is usually hampered by corruption of the GPS signal by multipath associated with passing vehicles, resulting to unrealistically large apparent displacements. Field data from the Gorgopotamos train bridge in Greece and systematic experiments revealed that such bias is due to superimposition of two major effects, (i) changes in the geometry of satellites because of partial masking of certain satellites by the passing vehicles (this effect can be faced with solutions excluding satellites that get temporarily blocked by passing vehicles) and (ii) dynamic multipath caused from reflection of satellite signals on the passing trains, a high frequency multipath effect, different from the static multipath. Dynamic multipath seems to have rather irregular amplitude, depending on the geometry of measured satellites, but a typical pattern, mainly consisting of a baseline offset, wide base peaks correlating with the sequence of main reflective surfaces of the vehicles passing next to the antenna. In cases of limited corruption of GPS signal by dynamic multipath, corresponding to scale distortion of the short-period component of the GPS waveforms, we propose an algorithm which permits to reconstruct the waveform of bridge deflections using a weak fusion of GPS and RTS data, based on the complementary characteristics of the two instruments. By application of the proposed algorithm we managed to extract semi-static and dynamic displacements and oscillation frequencies of a historical railway bridge under train loading by using noisy GPS and RTS recordings. The combination of GPS and RTS is possible because these two sensors can be fully collocated and have complementary characteristics, with RTS and GPS focusing on the long- and short-period characteristics of the displacement, respectively.

Degradation Kinetics of Three Veterinary Antibiotics in Composted and Stockpiled Manure

  • Kim, Sung-Chul;Yang, Jae-E.;Ok, Yong-Sik;Jung, Doug-Young;Carlson, Kenneth
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.1
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    • pp.43-50
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    • 2012
  • Two typical animal waste management practices, composting and stockpiling, were evaluated for their effect on the degradation of three veterinary antibiotics (VAs), chlortetracycline (CTC), tylosin (TYL), and monensin (MNS). The VAs were applied to horse manure plots subject to composting or stockpiling, and core samples were collected over a period of time. Selected buffer solutions were used to extract the VAs and analysis for concentration was conducted with solid phase extraction (SPE) followed by high performance liquid chromatography tandem mass spectrometry (HPLC/MS/MS) technique. The VAs demonstrated rapid dissipation within ten days followed by a gradual decrease in concentration until the end of the experimental period (141 days). All three VAs degraded more rapidly in the composting samples than in the stockpiling samples, particularly between 20 and 60 days of the observation period. Degradation of the three VAs generally followed a first-order kinetic model, and a fitted model with a calculated rate constant was determined for each treatment. TYL in composting showed the fastest degradation, with a calculated rate constant of $0.91day^{-1}$; the slowest degradation was exhibited by MNS in stockpiling, with rate constant of $0.17day^{-1}$. Calculated correlation coefficients ranged from 0.89 to 0.96, indicating a strong correlation between measured concentrations and fitted values in this study. Although concentration of TYL in composting treatment showed below detection limit during the test period, this study suggests that composting can reduce animal waste contaminants prior to field application as fertilizer.

ON THE RECURSIVE SEQUENCE $x_{n+1}=\frac{a+bx_{n-1}}{A+Bx^k_n}$

  • Ahmed, A. M.;El-Owaidy, H. M.;Hamza, Alaa E.;Youssef, A. M.
    • Journal of applied mathematics & informatics
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    • v.27 no.1_2
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    • pp.275-289
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    • 2009
  • In this paper, we investigate the global behavior of the difference equation $x_{n+1}\;=\;\frac{a+bx_{n-1}}{A+Bx^k_n}$, n=0,1,..., where a,b,$B\;{\in}\;[0,\infty)$ and A, $k\;{\in}\;(0,\infty)$ with non-negative initial conditions.

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Evaluation of Fineness Levels on the Sulfate Resistance of Cement Matrix with GGBS

  • Moon, H.Y.;Kim, S.S.;Lee, S.T.;Jung, H.S.;Kim, J.P.
    • Proceedings of the Korea Concrete Institute Conference
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    • 2003.05a
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    • pp.1097-1100
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    • 2003
  • This paper describes the sulfate resistance of cement pastes and mortar with or without ground granulated blast furnace slag (GGBS). Sulfate attack was performed on the cement pastes and mortar, which had been prepared by using a water-binder ratio of 0.45. Variables were the fineness levels of GGBS and the concentrations of two sulfate solution. In this present study, compressive strength and length change were carried out to evaluate the sulfate resistance of GGBS with various fineness levels. From the test results, it can be concluded that the deterioration modes of cement matrix with GGBS were dependent on the exposure solutions. Moreover, the influence of fineness levels of GGBS on the sulfate resistance was somewhat little because of a relative short exposure period.

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Optimal Solution of a Cyclic Task Using the Global Path Information for a Redundant Robot (여유자유도 로봇에 있어서 광역의 경로정보를 이용한 주기작업의 최적해)

  • 최병욱;원종화;정명진
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.29B no.3
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    • pp.6-15
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    • 1992
  • This paper proposes a method for the global optimization of redundancy over the whole task period for a kinematically redundant robot. The necessary conditions based on the calculus of variations for an integral type cost criterion result in a second-order differential equation. For a cyclic task, the periodic boundary conditions due to conservativity requirements are discussed. We refine the two-point boundary value problem to an initial value adjustment problem and suggest a numerical search method for providing the conservative global optimal solution using the gradient projection method. Since the initial joint velocity is parameterized with the number of the redundancy, we only search the parameter value in the space of as many dimensions as the number of degrees of redundancy. We show through numerical examples that multiple nonhomotopic extremal solutions and the generality of the proposed method by considering the dynamics of a robot.

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A Study on the phasic characteristics of organic thoughts in modern architecture (근대건축에 나타난 유기적 사고의 단계별 특성에 관한 연구)

  • 이근택
    • Journal of the Korean housing association
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    • v.12 no.3
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    • pp.61-73
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    • 2001
  • This study is to examine and classify the phasic characteristics of organic thoughts in modern architecture. Organic architects have applied organic thoughts to solutions for the problems of each period in architecture since modern times. As results of this study, the architecture of organic thoughts from 1850s to 1940s could be divided into two phases. The phasic characteristics of the first phase from 1850s to 1910s was physical resemblance in real or fantastic appearance that the work of art and architecture should imitate organic forms from the view of solid empiricism. The phasic characteristics of the second phase from 1920s to 1940s was organic growth that the form appropriate to a work of art and architecture should grow from the nature of the problem itself as a system in nature grows from the view of pragmatism and was organic unity that the form and function or the form and content of a work of art should be inseparably integrated as the form in nature should grow out of the inner nature of the thing and be an expression of that inner nature from the view of expressive theory.

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