• Clinical and Experimental Pediatrics
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• v.45 no.12
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• pp.1484-1490
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• 2002

Purpose : The purpose of this study was to look at prevalences of abnormal serum aminotransferase levels and abnormal serum total cholesterol levels among adolescents with obesity in Seoul area. Methods : Body mass index[$BMI(kg/m^2)$], serum aspartate aminotransferase(AST) alanine aminotransferase( ALT), and total cholesterol levels were measured in 26,876 adolescents(male : 13,287, female : 13,589) of first grade of high school in Seoul between the ages of 15 and 16 years, enrolled in a large health examination survey by Seoul School Health Center(SSHC) in 2001. Obesity was defined as BMI more than 95th percentile for age and sex and normal weight was defined as BMI between 25th percentile and 75th percentile for age and sex. Abnormal levels of AST, ALT and total cholesterol were defined as more than 95th percentile for age and sex. Results : The BMI at 95th percentile was 28.7 in males and 26.9 in females. The prevalence of abnormal AST levels was higher in obesity group than in normal weight group. In males, those were 23.7% and 3.7%, respectively(P<0.01, $x^2-value$ : 529.2). In females, those were 11.8% and 4.9 %, respectively(P<0.01, $x^2-value$ : 56.3). The prevalence of abnormal ALT levels was significantly higher in the obesity group compared with the normal weight group. In males, those were 33.9% and 1.7%, respectively(P<0.01, $x^2-value$ : 1,693.4). In females, those were 22.3% and 3.9%, repectively(P<0.01, $x^2-value$ : 397.6). The prevalence of abnormal total cholesterol levels was higher in the obesity group than in the normal weight group. In males, those were 16.8% and 3.5%, respectively(P<0.01, $x^2-value$ : 268.3). In females, those were 9.0% and 5.4%, respectively(P<0.01, $x^2-value$ : 14.2). Conclusion : This study revealed that the prevalences of abnormal AST, ALT and total cholesterol level were higher in the obese group than in the normal weight group.

• The Journal of Korean Medicine
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• v.39 no.4
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• pp.16-29
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• 2018

Introduction: We aimed to investigate the predictive factors and optimal age for response to herbal medicine treatment for height gain in children. Methods: This retrospective chart review included 61 children (age range, 5-16 years) treated for height gain between 2011 and 2015. A predictive model was established by multiple linear regression analysis. Dependent variables were defined by the differences in percentile before and after herbal medicine treatment. The optimal cutoff value of patient age was determined by receiver operating curve analysis. Results : The age of initiation of herbal medicine therapy (p = 0.012) and administration of Forsythiae fructus (p = 0.002) were significant variables for treatment response. The adjusted R2 value was 0.231. The mean ages of the responder and non-responder groups were significantly different (p = 0.023). The optimal cutoff value of age for predicting treatment response was 9.75 years. Treatment response was better among children below 9.75 years of age. Conclusions: Patient age and administration of Forsythiae fructus were identified as determinants of response to herbal medicine treatment. Treatment of rhinitis and initiation of height gain treatment at an early age are critical for better response. These findings will provide fundamental data for further research.

• IE interfaces
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• v.17 no.1
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• pp.1-12
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• 2004

In a modern semiconductor device manufacturing industry, statistical bin limits on wafer level test bin data are used for minimizing value added to defective product as well as protecting end customers from potential quality and reliability excursion. Most wafer level test bin data show skewed distributions. By Monte Carlo simulation, this paper evaluates methods and sample size effect regarding determination of statistical bin limits. In the simulation, it is assumed that wafer level test bin data follow the Poisson distribution. Hence, typical shapes of the data distribution can be specified in terms of the distribution's parameter. This study examines three different methods; 1) percentile based methodology; 2) data transformation; and 3) Poisson model fitting. The mean square error is adopted as a performance measure for each simulation scenario. Then, a case study is presented. Results show that the percentile and transformation based methods give more stable statistical bin limits associated with the real dataset. However, with highly skewed distributions, the transformation based method should be used with caution in determining statistical bin limits. When the data are well fitted to a certain probability distribution, the model fitting approach can be used in the determination. As for the sample size effect, the mean square error seems to reduce exponentially according to the sample size.

• Journal of the Korean Dietetic Association
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• v.2 no.2
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• pp.168-180
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• 1996

This study was accomplished to investigate the prevalence of obesity among the 229 elementary school children(boys; 115 persons, girls; 114 persons) during 4 years by retrospective study. The results were as follows; 1. The mean height and weight of 229 subjects were 143.2cm(boys;143.4cm, girls; 142.7cm), 38.8kg(boys;40.4kg, girls;36.9kg), respectively. And other anthropometric body index such as the mean BMI, Rohrer Index, WLI and Obesity Index of subjects were 18.8(boys;19.5, girls; 18.0), 1.31(boys;1.36, girls; 1.26), 115.5(boys;121.4, girls; 108.9) and 110.6(boys;114.5, girls; 106.7), respectively. 2. The mean percentile values of height and weight of subjects were higher than the '85 Korean Children's Growth Standard, respectively. In the case of boys, the 75th percentile value of weights was larger than that's 97th's. And in the case of girls, the 75th percentile value of weights was equalled to the that's 90th's. 3. When the subjects were classified into 4 groups such as obese, overweight, normal, and lean groups according to Obesity Index, their percentages were 28.8%(boys; 38.3%, girls; 19.3%), ll.8%(boys; 9.6%, girls; 14.0%), 50.7%(boys; 47.0%, girls; 54.4%) and 8.7%(boys; 5.2%, girls; 12.3%), respectively. And only I person(3.3%) is classified into normal group and 2 persons(6.7%) are classified into overweight group when they become 5 grade among 30 persons(13.1%) who were classified into obese group when they were I grade. 4. Changes in percentage of subjects differentiated by 3 indices during 4 years(from I grade to 5 grade) were as follows; In the case of BMI were 5.2%, 5.2%, 11.8%, 21.0%, 27.5%. In the case of Roher index were 13.1%, 11.8%, 14.4%, 14.8%, 17.8%. And in the case of WLI were 15.7%, 21.6%, 29.5%, 32.2%, 36.7%. 5. There was no significant difference among 4 groups on the skip rate of breakfast(obese;48.5%, overweight;55. mean meal time of subjects took about 10 minutes which was short, and the eating rate of obese group was significantly shorter than that of other groups(p<0.05). There was a tendency that the rate of the obese or overweight group eating together in breakfast and dinner was lower than that of normal or lean group. The mean T.V. watching time and the rate of eating out of subjects were 1-2 hours/day and 1 or 2 times/week. In conclusion, the subjects have been grown remarkably compared to the '85 Korean Children's Growth Standard, especially boy's weight. In order to the elementary school children to be grew as healthful citizen they should recognize the importance of meals of everyday, the balanced meals, and desirable eating habits. In addition to these, we should educate the ways of meal-life to them. We also are in need to develope the methods of education for the students themselves and their parents so that could prevent the increase rate of obesity.

• Fisheries and Aquatic Sciences
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• v.11 no.1
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• pp.7-14
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• 2008

The sanitary quality of a shellfish-growing area in Kamak Bay, Korea, was assessed through a bacteriological examination of seawater and oysters from January 2004 to December 2006. From seawater samples collected at 28 stations, the range of geometric mean (GM) and the estimated 90th percentile for most-probable-number (MPN) values of fecal coliforms were <1.8-2.4 MPN/100 mL and 1.8-6.0 MPN/100 mL, respectively. The observed fecal coliform GM and the estimated 90th percentile did not exceed the fecal coliform water quality standards of 14 MPN/100 mL and 43 MPN/100 mL. Therefore, the bacteriological quality of seawater at this shellfish-growing area met the Korean Shellfish Sanitation Program (KSSP) criteria for a growing area used for export. The range of the fecal coliform GM and the estimated 90th percentile MPN values of oyster samples were 19.2-160 MPN/100 g and 20.2-166.9 MPN/100 g, respectively, and the range of the viable cell count was 30-1900 CFU/g. Thus, the fecal coliform value for the oysters and the viable cell count were less than the current shellfish quality standards of 230 MPN/100 g and 50,000 CFU/g, respectively. The bacteriological quality of the oysters complied with the criteria for domestic use and export of shellfish.

• Journal of the Earthquake Engineering Society of Korea
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• v.22 no.2
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• pp.45-54
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• 2018

The seismically isolated nuclear power plants shall be designed for design basis earthquake (DBE) and considered to ensure safety against beyond design basis earthquake (BDBE). In order to limit the excessive displacement of the seismic isolation system of the seismically isolated structure, the moat is installed at a certain distance from the upper mat supporting the superstructure. This certain distance is called clearance to stop (CS) and is calculated from the 90th percentile displacement of seismic isolation system subjected to BDBE. For design purposes, the CS can be obtained simply by multiplying the median displacement of the seismic isolation system against DBE by scale factor with a value of 3. The DBE and BDBE used in this study were generated by using 30 sets of artificial earthquakes corresponding to the nuclear standard design spectrum. In addition, latin hyper cube sampling was applied to generate 30 sets of artificial earthquakes corresponding to maximum - minimum spectra. For the DBE, the median displacement and the 99th percentile displacement of the seismic isolation system were calculated. For the BDBE, the suitability of the scale factor was assessed after calculating the 90th percentile displacement of the seismic isolation system.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.436-441
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• 2007

This study was carried out to evaluate health effects of aircraft noise using THI(Todai Health Index). The questionnaire survey was conducted around the Gimpo International Airport in Seoul, Korea from 8 August to 9 September. Study subjects, 614 residents, were divided into three groups following to the aircraft noise level: under 75WECPNL(area(1)), $75{\sim}80$WECPNL(area(2)) and $80{\sim}85$WECPNL(area (3)). Twelve scale scores are converted to dichotomous variables based on scale scores of 90 percentile value or 10 percentile value in the control group. Logistic regression analysis taking twelve scores converted as the dependent variables and WECPNL(area), age, gender as the independent variables is conducted. Significant dose-response relationships are found in the scale of MOUT, DEPR, NERV, LIFE, where p denotes significance probability of trend test. Factor analysis was carried out and 2 factors are extracted which may be called "somatic factor" and "mental factor". The dose-response relationship with these factors and noise exposure is not clear. But strangely the odds ratio of mental factor in area 2 is the highest and the annoyance of this area is also higher than other areas.

• Journal of Nutrition and Health
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• v.46 no.1
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• pp.50-60
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• 2013

The aims of this study were to estimate daily intake of macrominerals from beverages, liquid teas, and liquid coffees and to evaluate their potential health risks for Korean children and adolescents (1-to 19 years old). Assessment of dietary intake was conducted using the actual level of sodium, calcium, phosphorus, potassium, and magnesium in non-alcoholic beverages and (207 beverages, 19 liquid teas, and 24 liquid coffees) the food consumption amount drawn from "The Fourth Korea National Health and Nutrition Examination Survey (2007-2009)". To estimate the dietary intake of non-alcoholic beverages, 6,082 children and adolescents (Scenario I) were compared with 1,704 non-alcoholic beverage consumption subjects among them (Scenario II). Calculation of the estimated daily intake of macrominerals was based on point estimates and probabilistic estimates. The values of probabilistic macromineral intake, which is a Monte-Carlo approach considering probabilistic density functions of variables, were presented using the probabilistic model. The level of safety for macrominerals was evaluated by comparison with population nutrient intake goal (Goal, 2.0 g/day) for sodium, tolerable upper intake level (UL) for calcium (2,500 mg/day) and phosphorus (3,000-3,500 mg/day) set by the Korean Nutrition Society (Dietary Reference Intakes for Koreans, KDRI). For total children and adolescents (Scenario I), mean daily intake of sodium, calcium, phosphorus, potassium, and magnesium estimated by probabilistic estimates using Monte Carlo simulation was, respectively, 7.93, 10.92, 6.73, 23.41, and 1.11, and 95th percentile daily intake of those was, respectively, 28.02, 44.86, 27.43, 98.14, and 3.87 mg/day. For consumers-only (Scenario II), mean daily intake of sodium, calcium, phosphorus, potassium, and magnesium estimated by probabilistic estimates using Monte Carlo simulation was, respectively, 19.10, 25.77, 15.83, 56.56, and 2.86 mg/day, and 95th percentile daily intake of those was, respectively, 62.67, 101.95, 62.09, 227.92, and 8.67 mg/day. For Scenarios I II, sodium, calcium, and phosphorus did not have a mean an 95th percentile intake that met or exceeded the 5% of Goal and UL.

• The Korean Journal of Pesticide Science
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• v.17 no.2
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• pp.117-125
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• 2013

A probabilistic exposure assessment was performed on the monitoring data of pesticides were assessed in agricultural products in Gyeonggi-do from 2006 to 2010. Chlorothalonil, chlorpyrifos, dicofol, endosulfan, EPN, ethoprophos, fenitrothion, methidathion, phenthoate and tebupirimfos were assessed. For this assessment, we used Monte Carlo simulation software and the distribution of concentration and intake were assumed to lognormal distribution by inputting mean and standard deviation. The hazard index (HI, %ADI) of average value and the $95^{th}$ percentile based on a probabilistic method were usually lower than those by a deterministic one. For the whole population, when non-detects data were assigned 0 mg/kg, HI of the average value and the $95^{th}$ percentile showed 0.05~0.70% and 0.11~1.94%, respectively. When nondetects data were assigned 0.005 mg/kg, HI of the average value and the $95^{th}$ percentile were 0.41~4.42% and 0.98~13.81%. For only consumers, when non-detects data were assigned 0 mg/kg, HI of the average value and the $95^{th}$ percentile were 1.24~10.16% and 3.72~33.81%, respectively. When non-detects data were assigned 0.005 mg/kg, HI of the average value and the $95^{th}$ percentile were 3.43~18.26% and 9.45~54.99%, respectively. Methidathion had highest values when both of 0 and 0.005 were assigned to non-detecs data for consumers only. This study showed that agricultural products in Gyeonggi-do were safe because they had less than 100 of HI (%ADI) based on probabilistic exposure assessment.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.1
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• pp.34-39
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• 2013

In this study, the quantitative analysis and pattern analysis of the error bounds with respect to recording period were carried out using the wave climate data from coastal areas. Arbitrary recording periods were randomly sampled from one month to six years using the bootstrap method. Based on the analysis, for recording periods less than one year, it was found that the error bounds decreased rapidly as the recording period increased. Meanwhile, the error bounds were found to decrease more slowly for recording periods longer than one year. Assuming the absolute estimate error to be around 10% (${\pm}0.1m$) for an one meter significant wave height condition, the minimum recording period for reaching the estimate error for Sokcho and Geoje-Hongdo stations satisfied this condition with over two years of data, while Anmado station was found to satisfy this condition when using observational data of over three years. The confidence intervals of the significant wave height clearly show an increasing pattern when the percentile value of the wave height increases. Whereas, the confidence intervals of the mean wave period are nearly constant, at around 0.5 seconds except for the tail regions, i.e., 2.5- and 97.5-percentile values. The error bounds for 97.5-percentile values of the wave height necessary for harbor tranquility analysis were found to be 0.75 m, 0.5 m, and 1.2 m in Sokcho, Geoje-Hongdo, and Anmado, respectively.