• 대한치과의사협회지
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• 제4권2호
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• pp.71-74
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• 1963

• Bulletin of the Korean Chemical Society
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• 제14권5호
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• pp.533-534
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• 1993

• 대한치과의사협회지
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• 제54권5호
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• pp.356-364
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• 2016

Aim: The purpose of this study was to identify dominant pathogens and their antimicrobial susceptibilities of endodontic infection in type II diabetes mellitus (DM) patients to determine effective empirical antibiotics. Methodology: Pathogens from endodontic infection in six patients with DM and in six patients without DM were cultured, identified and their antimicrobial susceptibility was tested using Vitek2 systems ($bioM{\acute{e}}rieux$, Marcy l' Etoile, France). The results were analyzed using Chi-square test and Fisher's exact test at P< 0.05 level. Results: Pathogens of opportunistic infection were dominant in DM patients (P=0.015). However, there was no significant difference of antimicrobial susceptibility between DM and non-DM patients. Relatively high percent (27%) of pathogens showed resistance to penicillin. Conclusions: More cautions should be paid to DM patients because they are prone to opportunistic infection. Penicillin is not effective in the control of endodontic infection.

• Journal of Chest Surgery
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• 제28권4호
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• pp.419-422
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• 1995

Pulmonary actinomycosis is a chronic pulmonary infection characterized by suppuration, abscess formation, and dense scarring. The causative agent, Actinomyces israelii, is a gram-positive, microaerophilic bacterium that resemble fungi. We recently treated two cases of pulmonary actinomycosis. A patient was underwent right lower lobectomy under the impression of bronchiectasis. Pulmonary actinomycosis was diagnosed of postoperatively. He was medicated with high-dose penicillin parenterally. The other patient was also undergone right lower lobectomy under the impression of broncholithiasis and received parenteral penicillin and oral roxythromycin. There was no recurrence or development of empyema. The purpose of this paper is to review of our experience and to enhance consideration of pulmonary actinomycosis.

• 대한의생명과학회지
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• 제5권1호
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• pp.131-133
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• 1999

본 연구는 methicillin 내성 Staphylococcus aureus (MRSA)에 특이적인 유전자인 mecA 유전자를 검출하기 위하여 전라북도의 두 병원에서 황색포도상구균 31주를 분리하였다. 이중 penicillin에 내성인 20균주를 디스크 확산법을 이용하여 methicillin, oxacillin, ampicillin, vancomycin, penicillin에 대한 다약제 내성 성상을 확인하였고, 중합효소 연쇄반응(PCR)을 이용하여 mecA 유전자를 확인하였다. 디스크 확산법을 실시한 결과 methicillin 내성균주는 20균주 중 10주 (50%)였다. Methicillin에 내성인 10균주를 PCR법으로 확인한 결과 7주에서 554 bp의 DNA증폭이 관찰되어 mecA 유전자가 존재함을 확인하였다.

• 한국식품영양학회지
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• 제11권3호
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• pp.289-292
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• 1998

1995년 12월부터 1996년 11월까지 약 1년간 광주시 및 전남지역에서 사육하고 있는 건강한 산양 20두와 건강한 개 30두, 총 50두로부터 분변을 채취하여 5균주의 C. perfringens을 분리 동정하였다. C. perfringens의 분리율은 건강한 산양 20두 중에서 3균주(15.0%)가 분리되었으며 건강한 개 30두 중에서 2균주(6.7%)가 분리되었다. C. perfringens의 항생제에 대한 감수성은 ampicillin, baytril 및 penicillin에 대해서는 분리균의 80%가 감수성을 나타내었고 cephalothin에 대해서는 60%가 감수성을 나타내었으며 erythromycin에 대해서는 40%가 감수성을 나타내었다.

• 한국임상약학회지
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• 제30권3호
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• pp.206-208
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• 2020

An 80-year-old Korean woman who previously experienced penicillin allergy presented to a dental hospital for treatment of a fractured tooth. A dentist extracted the tooth and prescribed her A-cillin (amoxicillin hydrate) 250 mg orally 3 times a day for 3 days and Carol-F^® (ibuprofen arginine) orally 3 times a day for 3 days. She received the prescriptions, returned home, and took one dose of each drug. One hour later, she experienced hypertension, itching, shortness of breath, and was unable to move her tongue to pronounce words. Approximately 6 hours after drug administration, the symptoms persisted, and the patient was admitted to an emergency medical center (EMC). The patient was discharged from the EMC after a one-night stay in the hospital for symptomatic treatment.

• 한국환경보건학회지
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• 제5권1호
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• pp.51-57
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• 1978

Antibiotics susceptibilities of Staphylococci were tested to get useful data for prevention food contamination and treatment of food poisoning. Tested were colony counts, isolation of Staphylococci, identification for the Staphylococcus aureus and resistant patterns to antimcrobial agents. The colonies and Staphylococci isolated from the atmosphere of 37 home kitchens in the morning (07:00-08:00) on Nov. 19, 1977 in Busan. The findings are as follows: 1. The average of colony counts was shown to be 9.6 ranging from 47 to 1 at mean temperature of 18$\circ$C (the highest 21$\circ$C, the lowest 15$\circ$C) 2. Out of total 37 kitchens, 18 Staphylococci were isolated from 15 kitchens with 40.5 per cent, and 4 Staphylococcus aureus were identified with 22.2 per cent from 18 Staphylococci. 3. Isolated Staphylococci were resistant to penicillin(100%), dihydrostreptomycin(93.3%), tetracycline (93.3%) and oleandomycin(66.6%), while the strains were sensitive to sulfonamide(88.6%) and colistin(83.3%). 4. Staphylococcus aureus identified were resistant to dihydrostreptomycin, penicillin and tetracycline, while the strains were sensitive to sulfonamide and colistin.

• Journal of Microbiology and Biotechnology
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• 제14권4호
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• pp.698-706
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• 2004

$\beta$-Lactam antibiotics such as penicillin G, amoxicillin, and ampicillin were determined by a potentiometric biosensor system which exploited penicillinase immobilized on Immobilon cellulose nitrate membrane and a flat-bottomed pH electrode-as the biological component and transducer. The optimum reaction buffer for maximum sensitivity was found as 2 mM of sodium phosphate buffer (pH 7.2). The detection limit of the biosensor could be extended to 1 $\mu{M}$ of the analytes by increasing the enzyme loading for immobilization to 100 units/$m\ell$. The model samples spiked with each of the standard penicillins were measured for their biosensor responses and HPLC peak area, resulting in the relative responses of 82.1-103.5% and 79.5-106.1% for the biosensor method along with HPLC analysis, respectively. This result showed a good precision of the current biosensor method for screening the penicillin compounds.

• 대한수의학회지
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• 제24권2호
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• pp.163-168
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• 1984

The in vitro activity of penicillins(penicillin G, ampicillin, carbenicillin, methicillin and cloxacillin) and gentamicin to Staphylococcus aureus and coagulase-negative staphylococci isolated from bovine mastitic milk samples was determined. The growth of all isolates of staphylococci tested was inhibited by cloxacillin and methicillin at a concentration of $0.78{\mu}g/ml$ and by gentamicin at a minimum inhibitory concentration (MIC) of $1.56{\mu}g/ml$. Of the 140 strains of Staphylococcus aureus isolated 99(70.7%) gave positive reactions for penicillinase on the starch-iodine test. Of 121 isolates of coagulase-negative staphylococci, 58(47.9%) showed penicillinase production, but all the Staph. xylosus lacked the ability to produce penicillinase. MIC of penicillin G of the penicillinase-positive strains was $0.2{\mu}g/ml$ or more. The combination of cloxacillin with gentamicin showed a synergistic effect by inhibiting regrowth of the tested organism.