Browse > Article
http://dx.doi.org/10.24304/kjcp.2020.30.3.206

Unusual Symptom of Hypertension associated with Amoxicillin  

Cho, Young Ah (Mokhwa Convalescent Hospital)
Choi, Eun Joo (College of Pharmacy, Chosun University)
Yoon, Hyonok (College of Pharmacy, Research Institute of Pharmaceutical Sciences, Gyeongsang National University)
Publication Information
Korean Journal of Clinical Pharmacy / v.30, no.3, 2020 , pp. 206-208 More about this Journal
Abstract
An 80-year-old Korean woman who previously experienced penicillin allergy presented to a dental hospital for treatment of a fractured tooth. A dentist extracted the tooth and prescribed her A-cillin (amoxicillin hydrate) 250 mg orally 3 times a day for 3 days and Carol-F® (ibuprofen arginine) orally 3 times a day for 3 days. She received the prescriptions, returned home, and took one dose of each drug. One hour later, she experienced hypertension, itching, shortness of breath, and was unable to move her tongue to pronounce words. Approximately 6 hours after drug administration, the symptoms persisted, and the patient was admitted to an emergency medical center (EMC). The patient was discharged from the EMC after a one-night stay in the hospital for symptomatic treatment.
Keywords
Amoxicillin; electronic medical records; hypertension; penicillin allergy;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Bhattacharya S. The facts about penicillin allergy: a review. J Adv Pharm Technol Res 2010;1(1):11-7.
2 Hyeon CW, Lee JY, Jang SG, et al. Medical malpractice related to drug-induced anaphylaxis: An analysis of lawsuit judgments in South Korea. Medicine (Baltimore) 2019;98(23):e15996.   DOI
3 Durkin MJ, Hsueh K, Sallah YH, et al. An evaluation of dental antibiotic prescribing practices in the United States. J Am Dent Assoc 2017;148(12):878-86.e1.   DOI
4 Podlecka D, Jerzynska J, Malewska-Kaczmarek K, Stelmach I. A case of a child with several anaphylactic reactions to drugs. Glob Pediatr Health 2019;6:2333794X19855287.
5 Schmitt BD, Krivit W. Benign intracranial hypertension associated with a delayed penicillin reaction. Pediatrics 1969;43(1):50-3.
6 Albin S, Agarwal S. Prevalence and characteristics of reported penicillin allergy in an urban outpatient adult population. Allergy Asthma Proc 2014;35(6):489-94.   DOI