• 제목/요약/키워드: peak identification

검색결과 280건 처리시간 0.021초

LPS로 유도한 RAW 264.7 세포의 염증반응에서 마치현(馬齒莧) 70% 에탄올 추출물의 항염증 효과 (The anti-inflammatory effect of Portulaca oleracea 70% EtOH Extracts on lipopolysaccharide-induced inflammatory response in RAW 264.7 cells)

  • 서상완
    • 대한본초학회지
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    • 제30권6호
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    • pp.33-38
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    • 2015
  • Objectives : Portulaca oleracea (PO) have been used as a traditional medicine to treat inflammatory diseases in Korea. However, the anti-inflammatory effect of PO ethanol extract on lipopolysaccharide (LPS)-induced inflammation is not well-known. Therefore, this study was performed to identify the anti-inflammatory effect of PO on LPS induced inflammatory.Methods : Identification of PO was conducted by comparison with purified standards by HPLC. To measure out the cytotoxicity of PO, author performed the MTT assay. To evaluate the anti-inflammatory effects of PO, author examined the inflammatory mediators such as nitric oxide (NO) and pro-inflammatory cytokines (tumor necrosis factor (TNF)-α, interleukin, (IL)-1β and IL-6) on RAW 264.7 cells. Author also examined molecular mechanisms such as mitogen-activated protein kinases (MAPKs) and nuclear factor-B (NF-κB) activation by western blot.Results : Three major components (peaks 1, 2, 3) were detected in both varieties and peak 1 was characterized as caffeic acid, peak 2 as p-coumaric acid, and peak 3 as ferulic acid by comparison of chromatographic properties with authentic standards. Extract from PO itself did not have any cytotoxic effect in RAW 264.7 cells. PO inhibited LPS-induced productions of inflammatory mediators such as NO and pro-inflammatory cytokines in RAW 264.7cells. In addition, PO inhibited the phosphorylation of extracellular signal-regulated kinase1/2 (ERK1/2), c-Jun NH2-terminal kinase (JNK) and NF-κB activation in RAW 264.7 cells.Conclusions : Above experiment data can be an important indicator for the identification of PO and this study suggest that treatment of PO could reduce the LPS-induced inflammation. Thereby, PO could be used as a protective agent against inflammation.

변형된 ELC 공진기와 다중 슬롯 공진기를 이용한 소형 4-비트 Chipless RFID 태그 (Compact 4-bit Chipless RFID Tag Using Modified ELC Resonator and Multiple Slot Resonators)

  • 여준호;이종익
    • 한국항행학회논문지
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    • 제26권6호
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    • pp.516-521
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    • 2022
  • 본 논문에서는 변형된 전계-결합 유도-용량성(ELC; electric field-coupled inductive-capacitive) 공진기와 다중 슬롯 공진기를 이용한 소형 4-비트 chipless RFID(radio frequency identification) 태그를 제안하였다. 변형된 ELC 공진기는 기존의 ELC 공진기에서 인터디지털-커패시터 구조를 사용하여 레이다 단면적(RCS; radar cross section)의 공진 피크 주파수를 낮추었다. 다중 슬롯 공진기는 거꾸로 된 U-모양의 도체에 길이가 다른 3개의 슬롯을 에칭하여 설계하였다. 변형된 ELC 공진기의 RCS 공진 피크 주파수는 3.216 GHz로 설계하였고, 다중 슬롯 공진기는 각각 4.122 GHz, 4.64 GHz, 5.304 GHz로 설계하였다. 제안된 소형 4-비트 태그를 두께 0.8 mm의 50 mm×20 mm 크기의 RF-301 기판에 제작하였다. 실험 결과, 제작된 4-비트 chipless RFID 태그의 공진 피크 주파수는 3.285 GHz, 4.09 GHz, 4.63 GHz, 5.31 GHz로 0.78% ~ 2.16% 범위의 오차를 나타내며 시뮬레이션 결과와 유사하게 측정되었다.

대역별로 여과한 음성 강도의 차이값과 상관계수에 의한 화자확인 연구 (A Study on Speaker Identification by Difference Sum and Correlation Coefficient of Intensity Levels from Band-pass Filtered Sounds)

  • 양병곤
    • 음성과학
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    • 제10권2호
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    • pp.249-258
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    • 2003
  • This study attempted to examine a speaker identification method using difference sum and correlation coefficient determined from a pair of intensity level matrices of band-pass-filtered numeric sounds produced by ten female speakers of similar age and height. Subjects recorded three digit numbers at a quiet room at a sampling rate of 22 kHz on a personal computer. Collected data were band-pass-filtered at five different band ranges. Then, matrices of five intensity levels at 100 proportional time points were obtained. Pearson correlation coefficients and the sum of absolute intensity differences between a pair of given matrices were determined within and across the speakers. Results showed that very high correlation coefficient and small difference sum generally occurred within each speaker but some individual variation was also observed. Thus, the matrix pair with a higher coefficient and a smaller difference sum was averaged to form each individual's model. Comparison among the speakers yielded generally low coefficients and large differences, which suggests successful speaker identification, but among them there were a few cases with very high coefficients and small differences. Future studies will focus on finer band ranges and additional spectral parameters at some peak points of the intensity contour at a low frequency band.

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NEW DEVELOPMENT OF HYPERGAM AND ITS TEST OF PERFORMANCE FOR γ-RAY SPECTRUM ANALYSIS

  • Park, B.G.;Choi, H.D.;Park, C.S.
    • Nuclear Engineering and Technology
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    • 제44권7호
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    • pp.781-790
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    • 2012
  • The HyperGam program was developed for the analysis of complex HPGe ${\gamma}$-ray spectra. The previous version of HyperGam was mainly limited to the analysis of ${\gamma}$-ray peaks and the manual logging of the result. In this study, it is specifically developed into a tool for the isotopic analysis of spectra. The newly developed features include nuclide identification and activity determination. An algorithm for nuclide identification was developed to identify the peaks in the spectrum by considering the yield, efficiency, energy and peak area for the ${\gamma}$-ray lines emitted from the radionuclide. The detailed performance of nuclide identification and activity determination was accessed using the IAEA 2002 set of test spectra. By analyzing the test spectra, the numbers of radionuclides identified truly (true hit), falsely (false hit) or missed (misses) were counted and compared with the results from the IAEA 2002 tests. The determined activities of the radionuclides were also compared for four test spectra of several samples. The result of the performance test is promising in comparison with those of the well-known software packages for ${\gamma}$-ray spectrum analysis.

TV 광고 식별을 위한 Constant-Q 변환 기반의 오디오 핑거프린팅 방식 (Audio Fingerprinting Based on Constant Q Transform for TV Commercial Advertisement Identification)

  • 류상현;김형국
    • 한국음향학회지
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    • 제33권3호
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    • pp.210-215
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    • 2014
  • 오디오 핑거프린팅 기술은 잡음과 에코 등으로 인한 왜곡에도 성공적으로 음원을 식별해야한다. 이러한 오디오 핑거프린팅 기술을 TV광고식별에 적용하고자 한다. 본 논문은 TV 광고 식별을 위한 강인한 오디오 핑거프린팅 방식을 제안한다. 제안된 방법에서 사용되는 Constant Q 변환 기반에서 추출된 현저한 오디오 피크 쌍 핑거프린트는 실제 다양한 잡음환경에서 오디오 핑거프린팅 시스템의 정확도를 향상시키고, 낮은 복잡도를 가진다. 실험결과는 제안된 방식이 기존의 오디오 핑거프린팅 방식에 비해 다양한 잡음환경에서도 안정적이며 신뢰할 수 있는 검색 정확도를 제공함을 보여준다.

Load Modeling based on System Identification with Kalman Filtering of Electrical Energy Consumption of Residential Air-Conditioning

  • Patcharaprakiti, Nopporn;Tripak, Kasem;Saelao, Jeerawan
    • International journal of advanced smart convergence
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    • 제4권1호
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    • pp.45-53
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    • 2015
  • This paper is proposed mathematical load modelling based on system identification approach of energy consumption of residential air conditioning. Due to air conditioning is one of the significant equipment which consumes high energy and cause the peak load of power system especially in the summer time. The demand response is one of the solutions to decrease the load consumption and cutting peak load to avoid the reservation of power supply from power plant. In order to operate this solution, mathematical modelling of air conditioning which explains the behaviour is essential tool. The four type of linear model is selected for explanation the behaviour of this system. In order to obtain model, the experimental setup are performed by collecting input and output data every minute of 9,385 BTU/h air-conditioning split type with $25^{\circ}C$ thermostat setting of one sample house. The input data are composed of solar radiation ($W/m^2$) and ambient temperature ($^{\circ}C$). The output data are power and energy consumption of air conditioning. Both data are divided into two groups follow as training data and validation data for getting the exact model. The model is also verified with the other similar type of air condition by feed solar radiation and ambient temperature input data and compare the output energy consumption data. The best model in term of accuracy and model order is output error model with 70.78% accuracy and $17^{th}$ order. The model order reduction technique is used to reduce order of model to seven order for less complexity, then Kalman filtering technique is applied for remove white Gaussian noise for improve accuracy of model to be 72.66%. The obtained model can be also used for electrical load forecasting and designs the optimal size of renewable energy such photovoltaic system for supply the air conditioning.

Modal testing and finite element model calibration of an arch type steel footbridge

  • Bayraktar, Alemdar;Altunisk, Ahmet Can;Sevim, Baris;Turker, Temel
    • Steel and Composite Structures
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    • 제7권6호
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    • pp.487-502
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    • 2007
  • In recent decades there has been a trend towards improved mechanical characteristics of materials used in footbridge construction. It has enabled engineers to design lighter, slender and more aesthetic structures. As a result of these construction trends, many footbridges have become more susceptible to vibrations when subjected to dynamic loads. In addition to this, some inherit modelling uncertainties related to a lack of information on the as-built structure, such as boundary conditions, material properties, and the effects of non-structural elements make difficult to evaluate modal properties of footbridges, analytically. For these purposes, modal testing of footbridges is used to rectify these problems after construction. This paper describes an arch type steel footbridge, its analytical modelling, modal testing and finite element model calibration. A modern steel footbridge which has arch type structural system and located on the Karadeniz coast road in Trabzon, Turkey is selected as an application. An analytical modal analysis is performed on the developed 3D finite element model of footbridge to provide the analytical frequencies and mode shapes. The field ambient vibration tests on the footbridge deck under natural excitation such as human walking and traffic loads are conducted. The output-only modal parameter identification is carried out by using the peak picking of the average normalized power spectral densities in the frequency domain and stochastic subspace identification in the time domain, and dynamic characteristics such as natural frequencies mode shapes and damping ratios are determined. The finite element model of footbridge is calibrated to minimize the differences between analytically and experimentally estimated modal properties by changing some uncertain modelling parameters such as material properties. At the end of the study, maximum differences in the natural frequencies are reduced from 22% to only %5 and good agreement is found between analytical and experimental dynamic characteristics such as natural frequencies, mode shapes by model calibration.

통계적 극점 자취 알고리즘에 기초한 움직임 열화 영상의 파라메터 추출 (Estimation of Motion-Blur Parameters Based on a Stochastic Peak Trace Algorithm)

  • 최병철;홍훈섭;강문기
    • 방송공학회논문지
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    • 제5권2호
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    • pp.281-289
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    • 2000
  • 영상을 획득하는 과정에 있어서 영상 획득 장치 또는 피사체의 흔들림은 영상에 손상을 가져온다. 이러한 손상을 움직임 열화(motion blur)라고 부르며, 영상의 선명도를 떨어뜨리는 주된 원인이 된다. 최근 연구에서 밝힌 극점자취 방법을 통해 주어진 열화영상에서 열화의 PSF(Point Spread Function) 특성을 구하는데 사용되는 중요한 파라메터를 추출 할 수 있다. 이러한 극점 자취방법으로, 노이즈에 의한 열화에 관계없이 적은 연산량으로 움직임 열화의 방향을 추출할 수 있다. 본 논문에서는 통계적 극점 자취 접근법을 새롭게 제안한다. 저주파 영역에서 움직임 열화방향의 추정오차를 줄이기 위해 ML(Maximum Likelihood)분류를 통해 오차를 유발하는 극점을 선택하여 가중치를 적용, 그 영향을 최소화한다. 선형 예측법을 사용하여, 불규칙적 자료가 극점으로 선택되는 것을 방지한다 제안된 MALM(Moving average least mean)방법은 두번째로 큰 극점의 검출을 위해 움직임의 정도를 판별하는데 사용된다. MALM방법은 자체적으로 노이즈 제거 과정을 내포하고 있으므로 노이즈가 많은 환경에서도 파라메터를 추출할 수가 있다. 실험에서 우리는 제안된 방법을 통해 얻어진 정보를 사용하여, 열화 된 이미지를 효율적으로 복구해 낼 수 있었다.

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Evaluation of MALDI Biotyping for Rapid Subspecies Identification of Carbapenemase-Producing Bacteria via Protein Profiling

  • Somboro, Anou M.;Tiwari, Dileep;Shobo, Adeola;Bester, Linda A.;Kruger, Hendrik G.;Govender, Thavendran;Essack, Sabiha Y.
    • Mass Spectrometry Letters
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    • 제5권4호
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    • pp.110-114
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    • 2014
  • The method of direct mass spectrometry profiling is reliable and reproducible for the rapid identification of clinical isolates of bacteria and fungi. This is the first study evaluating the approach of MALDI-TOF mass spectrometry profiling for rapid identification of carbapenemase-resistant enterobacteriaceae (CRE). Proof of concept was achieved by the discrimination of CRE using MALDI Biotyper MS based on the protein. This profiling appears promising by the visual observation of consistent unique peaks, albeit low intensity, that could be picked up from the mean spectra (MSP) method. The Biotyper MSP creation and identification methods needed to be optimized to provide significantly improved differences in scores to allow for subspecies identification with and without carbapenemases. These spectra were subjected to visual peak picking and in all cases; there were pertinent differences in the presence or absence of potential biomarker peaks to differentiate isolates. We also evaluated this method for potential discrimination between different carbapenemases bacteria, utilizing the same strategy. Based on our data and pending further investigation in other CREs, MALDI-TOF MS has potential as a diagnostic tool for the rapid identification of even closely related carbapenemases but would require a paradigm shift in which Biotyper suppliers enable more flexible software control of mass spectral profiling methods.

열분석 방법을 이용한 AISI 5160스프링강의 용접시 Heat Affected Zone에서의 결합규명과 수소취성에 관한 연구 (A study on the identification of the weld defects and hydrogen embrittlement in heat affected zone of AISI 5160 spring steel using thermal analysis technique)

  • 김민태;이재영
    • Journal of Welding and Joining
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    • 제5권1호
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    • pp.34-41
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    • 1987
  • To explore the possible application of thermal analysis technique as a probe for finding weld defects, Hydrogen trapping phenomena in Heat Affected Zone (HAZ) of the AISI 5160 spring steel were investigated. HAZ was divided into five parts, which were used as thermal analysis specimens. Two types of trap sites were found in HAZ, ferrite/cementin interface and microvoid. The thermal analysis peak due to the ferrite/cementite interface increased its height toward the weld deposit. The thermal analysis peak due to the microvoid was the highest where the grain size was the smallest. The correspondence between the cold cracking and hydrogen trap nature is also discussed.

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