• Geomechanics and Engineering
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• 제21권6호
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• pp.537-549
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• 2020

The presence of cracks changes the water content pattern during seepage through a cracked soil as compared to that of intact soil. In addition, several different crack networks may form in one soil type. These two factors result in a variation of water contents in the soil matrix part of a cracked soil during seepage. This paper presents an investigation of the effect of crack network representation on the water content of the soil matrix part of cracked soil using numerical models. A new method for the numerical generation of crack networks incorporating connections among crack endpoints was developed as part of the investigation. Numerical analysis results indicated that the difference in the point water content was large, whereas the difference in the average water content was relatively small, indicating the uniqueness of the crack network representation on the average water content of the soil matrix part of cracked soil.

• Genomics & Informatics
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• 제17권2호
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• pp.18.1-18.10
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• 2019

Prediction of the relations among drug and other molecular or social entities is the main knowledge discovery pattern for the purpose of drug-related knowledge discovery. Computational approaches have combined the information from different sources and levels for drug-related knowledge discovery, which provides a sophisticated comprehension of the relationship among drugs, targets, diseases, and targeted genes, at the molecular level, or relationships among drugs, usage, side effect, safety, and user preference, at a social level. In this research, previous work from the BioNLP community and matrix or matrix decomposition was reviewed, compared, and concluded, and eventually, the BioNLP open-shared task was introduced as a promising case study representing this area.

• 한국컴퓨터정보학회논문지
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• 제25권9호
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• pp.53-62
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• 2020

최근 연구된 상품 추천 서비스들은 고객들의 구매 이력을 통해서만 추천이 이루어졌다. 본 논문에서는 구매 이력을 통해 추천뿐만 아니라 고객이 상품을 고를 때 취하는 행동 패턴을 분석하여 관심도가 높은 광고를 노출하는 행동 패턴 분석 기반 디지털 사이니지 서비스를 제안한다. 이 서비스는 고객행동 패턴을 분석하여 실질적으로 관심을 가지는 상품에 대해 관심도를 추출한다. 추출된 관심도와 고객들의 구매 이력을 Wide & Deep 모델을 통해 학습하고, 이를 바탕으로 MF(Matrix Factorization) 모델을 통해 다른 상품들의 희소 벡터를 예측한다. 예측된 상품 관심도에 대한 순위를 도출하고, 적합한 광고를 노출하기 위해 고객과 상호 작용할 수 있는 인도어 사이니지를 활용한다. 본 논문의 서비스를 통해 온라인뿐만이 아닌 오프라인 환경에서도 고객의 관심 정보를 파악하고 단순히 무작위로 노출하는 광고가 아닌 고객에게 적합한 광고를 제공하여 만족도 높은 구매 환경이 조성될 것이다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.1183-1188
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• 2005

In this paper, we propose a 3D automated measuring system which measures the mandibular movements and the reference plane of the jaw movements. In diagnosis and treatment of the malocclusions, it is necessary to estimate the mandibular movements and the reference plane of the jaw movements. The proposed system is configured with double stereo-cameras, PC, two moving pattern plates(MPPs), two fixed pattern plates(FPPs) and one orbital marker. The virtual pattern plate is applied to calculate the homogeneous transformation matrices which describe the coordinates systems of the FPP and MPP with respect to the world coordinates system. To estimate the parameters of the hinge axis, the Euler's theorem is applied. The hinge axis points are intersections between the FPPs and the hinge axis. The coordinates of a hinge axis point with respect to the MPP coordinates system are set up to fixed value. And then, the paths of the jaw movement can be calculated by applying the homogeneous transformation matrix to fixed hinge axis point. To examine the accuracy of the measurements, experiments of measuring the hinge axis points and floating paths of them are performed using the jaw motion simulator. As results, the measurement errors of the hinge axis points are within reasonable boundary, and the floating paths are very similar to the simulator's moving path.

• 한국통신학회논문지
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• 제17권12호
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• pp.1437-1450
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• 1992

본 논문에서는 손바닥의 interdigital영역으로 부터 특징패턴을 추출하는 과정과 이 특징패턴과 관련된 자료를 이용한 개인식별 방법을 제안하였다. 처리과정은 interdigital영역을 일정한 크기로 분할하고 각 분할된 영역에 대하여 융선의 분포에 따른 4방향의 방향 코드를 부여한후 이것을 분석하는 것에 의해 특징패턴의 존재 유무와 1차 중심점을 검출하였다. 검출된 1차 중심점의 주변 제한된 영역에 대해서만 세선화와 융선 추적을 통하여 특징패턴의 종류와 2차 중심점(core)을 구하였다. 2차 중심점들을 연결하는 특징패턴 좌표계를 설정하고 각 중심점에 대한 상대적 거리와 방향정보 특징 패턴의 종류등에 대한 특징 파라미터를 구하였다. 식별실험은 각 특징패턴의 종류와 수, 존재위치에 의하여 판단하거나 특징 파라미터를 비교, 분석하는 것에 의해 수행하였다.

• BMB Reports
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• 제28권2호
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• pp.177-183
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• 1995

The activity of aldehyde dehydrogenase (ALDH) in the cerebrum, cerebellum, striatum, and medulla oblongata was examined and mitochondrial matrix ALDH was purified prior to immunohistochemical study on the localization of ALDH isozymes in pig brain. Relatively high enzyme activity was found in the striatum and medulla oblongata when using indole-3-acetaldehyde as substrate, and in the striatum when using 3,4-dihydroxyphenylacetaldehyde (DOPAL). The main part of mitochondrial ALDH activities with both acetaldehyde and DOPAL existed in the matrix fraction. The ratio of activity of the matrix to the membrane fraction in the cerebrum was higher than in the cerebellum, suggesting that the distribution pattern of ALDH isozymes was different according to the brain regions. The 276-fold purified mitochondrial matrix ALDH from pig brain was identified to be homologous tetramers with 53 KD subunits. The enzyme showed maximal activity at pH 9.0 and was stable in the temperature range from $25^{\circ}C$ to $37^{\circ}C$. The mitochondrial matrix ALDH activity was considerably inhibited by acetaldehyde in vitro. The $K_m$ values of the enzyme for acetaldehyde and propionaldehyde were 5.8 mM and 4.9 mM, respectively, whereas $K_m$ values for indole-3-acetaldehyde and DOPAL were 44 ${\mu}M$ and 1.6 ${\mu}M$, respectively. The $V_{max}/K_{m}$ ratio was the highest with DOPAL as compared with other substrates. These results suggested that mitochondrial matrix ALDH in the present work might be a low Km isozyme involved in biogenic aldehyde oxidation in pig brain.

• 제어로봇시스템학회논문지
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• 제12권9호
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• pp.935-944
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• 2006

EMG pattern recognition is essential for the control of a multifunction myoelectric hand. The main goal of this study is to develop an efficient feature projection method for EMC pattern recognition. To this end, we propose a linear supervised feature projection that utilizes linear discriminant analysis (LDA). We first perform wavelet packet transform (WPT) to extract the feature vector from four channel EMC signals. For dimensionality reduction and clustering of the WPT features, the LDA incorporates class information into the learning procedure, and finds a linear matrix to maximize the class separability for the projected features. Finally, the multilayer perceptron classifies the LDA-reduced features into nine hand motions. To evaluate the performance of LDA for the WPT features, we compare LDA with three other feature projection methods. From a visualization and quantitative comparison, we show that LDA has better performance for the class separability, and the LDA-projected features improve the classification accuracy with a short processing time. We implemented a real-time pattern recognition system for a multifunction myoelectric hand. In experiment, we show that the proposed method achieves 97.2% recognition accuracy, and that all processes, including the generation of control commands for myoelectric hand, are completed within 97 msec. These results confirm that our method is applicable to real-time EMG pattern recognition far myoelectric hand control.

• IMMUNE NETWORK
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• 제4권2호
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• pp.116-122
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• 2004

Background: LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM). LIGHT is known to have proinflammatory roles in atherosclerosis. Methods: To find out the expression pattern of LIGHT in atherosclerotic plaques, immunohistochemical analysis was performed on human carotid atherosclerotic plaque specimens. LIGHT induced atherogenic events using human monocytic cell line THP-1 were also investigated. Results: Immunohistochemical analysis revealed expression of LIGHT and TR2 in foam cell rich regions in the atherosclerotic plaques. Double immunohistochemical analysis further confirmed the expression of LIGHT in foam cells. Stimulation of THP-1 cells, which express TR2, with either recombinant LIGHT or immobilized anti-TR2 monoclonal antibody induced interleukin-8 and matrix metalloproteinase(MMP)-9. Electrophoretic mobility shift assay demonstrated that LIGHT induces nuclear localization of transcription factor, nuclear factor $(NF)-{\kappa}B$. LIGHT induced activation of MMP-9 is mediated by $NF-{\kappa}B$, since treatment of THP-1 cells with the $NF-{\kappa}B$ inhibitor PDTC (pyrrolidine dithiocarbamate) completely blocked the activation of MMP-9. Conclusion: These data indicate that LIGHT is expressed in foam cells in atherosclerotic plaques and is involved in atherogenesis through activation of pro-atherogenic cytokine IL-8 and destabilization of plaque by inducing matrix degrading enzyme.

• 한국주조공학회지
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• 제16권2호
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• pp.109-115
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• 1996

Effect of various austempered structures on fracture characteristics of C/V graphite cast iron has studied. The tensile strength and hardness reached the maximum value of 971.4MPa and HB302 at the austempering temperature of $250^{\circ}C$, respectively. As the austempering temperature increased, the amount of retained austenite increased from 18% to 22, 29%, while $K_{IC}$ values ranged from the value of $65MPa{\cdot}m^{12} to 70MPa{\cdot}m^{1/2}, 66MPa{\cdot}m^{1/2}. This fact that $K_{IC}$ value was not sensitive to the increase of the amount of the retained austenite was that $K_{IC}$ was dependent on the matrix structure in lower bainitic matrix, while dependent on the notch effect from C/V graphite shape in upper bainitic matrix. Fractured surfaces showed a ductile fracture pattern at $300^{\circ}C$. Very large coalescence by C/V graphite and relatively small voids by spheroidal graphite were observed.

• 대한세포병리학회지
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• 제7권1호
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• pp.23-30
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• 1996

Chromatin texture, which partly reflects nuclear organization, is evolving as an important parameter indicating cell activation or transformation. In this study, chromatin pattern was evaluated by image analysis of the electron micrographs of follicular and papillary carcinoma cells of the thyroid gland and tested for discrimination of the two neoplasms. Digital grey images were converted from the electron micrographs, nuclear images, excluding nucleolus and intranuclear cytoplasmic inclusions, were obtained by segmentation; grey levels were standardized; and grey level histograms were generated. The histograms in follicular carcinoma showed Gaussian or near-Gaussian distribution and had a single peak, whereas those in papillary carcinoma had two peaks(bimodal), one at the black zone and the other at the white zone. In papillary carcinoma, the peak in the black zone represented an increased amount of heterochromatin particles and that at the white zone represented decreased electron density of euchromatin or nuclear matrix. These results indicate that the nuclei of follicular and papillary carcinoma cells differ in their chromatin pattern and the difference may be due to decondensed chromatin and/or matrix substances.