• The Journal of Society for e-Business Studies
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• v.22 no.3
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• pp.87-103
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• 2017

In recent years, many small and medium-sized manufacturing companies are making process innovation and product innovation through the public knowledge services. K Research institute provides different types of knowledge services in combination and due to this complexity, it is difficult to analyze the performance of knowledge service programs precisely. In this study, we derived performance items from bottom-up viewpoints, rather than top-down approaches selecting those items as in previous performance analysis. As a result, 74 items were finded from 82 companies in the K Research Institute case book, and the final result was refined to 17 items. After that a case-performance matrix was constructed, and binary data was entered to analyze. As a result, three clusters were identified through K-means clustering as 'enhancement of core competitiveness (product and patent),' 'expansion of domestic and overseas market,' and 'improvement of operational efficiency.'

• The Journal of Korean Academy of Sensory Integration
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• v.18 no.1
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• pp.1-12
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• 2020

Objective : In this study, we are going to check the impact of the daily performance of a child with developmental disabilities on the parent's burden and quality of life. Methods : 120 parents of children with developmental disabilities were targeted in Chungcheong and Jeolla provinces. To measure the daily performance ability of children with developmental disabilities, we used evaluative Pediatric Evaluation of Disability Inventory and The burden of parents was measured by Family Burden Questionnaire and the quality of life by Beach Center Family Quality of Life Scale. Based on the data collected, independent t-test, one-way anova, Pearson correlation analysis and regression analysis were conducted to check the impact of a child's daily performance ability of developmental disability on the parent's burden and quality of life. Results : The daily performance ability of a children with developmental disabilities showed a negative correlation with the burden of the parents and a positive correlation with the quality of life. The hygiene and bowel & bladder control of children with developmental disabilities had an important influence on parent's burden, while hygiene, toileting, and bowel & bladder control of children with developmental disabilities had a significant effect on their parent's quality of life. Conclusion : It has been shown that the daily performance ability of a children with developmental disabilities has a major influence on parent's burden and quality of life. In order to reduce the burden and improve quality of life, therapeutic intervention, education and interview programs for daily life of children with developmental disabilities need to be carried out systematically by occupational therapists.

• IMMUNE NETWORK
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• v.3 no.1
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• pp.16-22
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• 2003

Background: The S100A2 gene, also known as S100L or CaN19, encodes a protein comprised of 99-amino acids, is a member of the calcium-binding proteins of EF-hand family. According to a recent study, this gene was over-expressed in several early and malignant carcinomas compared to normal tissues. To elucidate the role of S100A2 protein in the process during carcinogenesis, production of monoclonal antibody specific to the protein is essential. Methods: First, cDNA sequence coding for ORF region of human S100A2 gene was amplified and cloned into an expression vector to produce GST fusion protein. Recombinant S100A2 protein and subsequently, monoclonal antibody to the protein were produced. The specificity of anti-S100A2 monoclonal antibody was confirmed by immunoblot analysis of cross reactivity to other recombinant proteins of S100A family (GST-S100A1, GST-S100A4 and GST-S100A6). To confirm the relation of S100A2 to cervical carcinogenesis, S100A2 protein in early cervical carcinoma tissue was immunostained using the monoclonal antibody. Results: GST-S100A2 recombinant protein was purified by affinity chromatography and then fusion protein was cleaved and S100A2 protein was isolated. The monoclonal antibody (KK0723; Korean patent pending #2001-30294) to the protein was produced and the antibody did not react with other members of EF-hand family proteins such as S100A1, S100A4 and S100A6. Conclusion: These data suggest that anti-S100A2 monoclonal antibody produced in this study can be very useful for the early detection of cervical carcinoma and elucidation of mechanism during the early cervical carcinogenesis.

• Journal of the Korean Society for Library and Information Science
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• v.51 no.4
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• pp.35-52
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• 2017

This paper aims to explore the citation patterns of conference papers in 'Information Science' discipline and to analze impacts of various cited works-related factors on future citations of conference papers. Existing bibliometric studies has investigated citation patterns and the statistical relations between a variety of bibliographic factors and the future citations of literature. However, the attentions have been focused largely on journal articles, and the bibliometric studies targeting conference papers are still in an infant stage. Therefore, this study, which is based on 1,904 conference papers in 'Information Science' field, examined several citation patterns and the contributions of the factors about cited works - the number of cited works, type of cited works, citation rates and ages of cited works at the time of being cited and the rate of self-citedness - to the future citation of the citing target articles. The data source of this study including the properties of target articles and cited works and citation rates of target articles was Scopus. As the results, 53% and 29% of the cited works were conference papers and journal articles, respectively. 14% of them are non-traditional types such as web pages, technical reports, patent, etc. More than 60% of the cited works were 5 years old or less. Among several factors considered in this paper, the number of conference papers and the number of non-traditional types of works are the most contributing factors on the citation rates of target articles. The recency of the cited works is also significant contributor on the citation rates of target articles. That is, the target articles citing more conference papers and non-traditonal types of works earned more citations. The target articles citing recent works also earned more citations.

• Journal of Chest Surgery
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• v.32 no.8
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• pp.702-708
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• 1999

Background: Surgical closure of the PDA in premature infants with complications or contraindications to indomethacin use, or recurrence of symptomatic PDA is a safe and effective procedure with low operative risk and minimal complications. Material and Method: From April 1996 to August 1998, 11 premature infants with body weight under 1.5 kg at operation underwent operation for a symptomatic PDA (male:5, female: 6). Associated dise ases were congenital heart disease(7), hyaline membrane disease(6), intraventricular hemor rhage(4), pneumonia(4), pneumothorax(3), hyperbilirubinemia(2), necrotizing enterocolitis(2), renal failure(1), epilepsy(1), and hydrocephalus(1). Surgical techniques are hemoclipping(8) and ligation(3). The size of PDA was 3~6 mm (5.0$\pm$1.2). Result: Systolic and diastolic blood pressure rised and heart rates decreased after PDA closure. ABGA improved postoperatively. There were no surgical complications. Six infants with improved ABGA data were weaned from mechanical ventilatory support. The follow-up durations after discharge were 3 month to 12 month. Five deaths were not related to operation. The causes of death were hyaline membrane disease(2), bronchopulmonary dysplasia with pneumonia(1), sepsis(1), and con gestive heart failure with respiratory distress syndrome(1). Conclusion: Early operative closure is the treatment of choice in most premature infants with a hemodynamically significant shunt(PDA), recurrence of symptomatic PDA, complications of Indomethacin, or contraindi cations to Indomethacin.

• Journal of Distribution Science
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• v.17 no.2
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• pp.53-69
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• 2019

Purpose - National scientific technology R&D investment is exceeding 60 trillion won per year, and the results of patent applications and technology transfers are visually improving. However, despite the improving research results of national R&D, the practical results of technology startups are mediocre. It is now time to expand the construction of the technology commercialization ecosystem, where the expansion of national R&D leads to the results of technology startups. Therefore, this study discussed the measures to increase the competitiveness of technology startups through the factual survey of the companies that benefitted from R&D support programs. Research design, data, and methodology - This study targeted 996 companies that benefitted from the R&D projects of the Technology Transfer Center for National R&D Programs, and deducted itemized issues through the survey replies. Survey questions were prepared to estimate the national R&D results, and the technology recognition path, the purpose of detailed introduction of the technology, investment of the commercialization fund, economic results, and the factors of success and failure were analyzed. Results - As for the recognition rate of technology during the process of corporate technology commercialization through the technology transfer, recognition through project participation showed a high response rate, and diverse implications of technology commercialization were deducted through the analysis of economic results. As for the resolution alternatives, the proliferation of technology commercialization platform that can create excellent technology for the companies in early stages and the measure of expanding the distribution of technology infrastructure were suggested. In this study, public technology commercialization strategy is established, and the innovative marketing strategy is presented. Conclusions - This study reveal that the result of creating scientific technology jobs should be deducted, in order to produce the revolutionary results of job creation by suggesting the success models of technology commercialization based on domestic scientific technology. In particular, even though the support systems for public research results are being diversely suggested, accurate studies on their actual conditions are currently lacking. Therefore, this study suggest realistic political alternatives to assure results in the process of public technology commercialization, by examining the current state of public research results of R&D support institutions and diagnosing the issues.

• Journal of Korea Technology Innovation Society
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• v.11 no.4
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• pp.510-531
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• 2008

The importance of universities' knowledge to industrial innovation have widely pervaded the academia as well as policy communities. During the last three decades, a series of policy measures vitalizing the knowledge-transfer activities of academics have been implemented both in industrialized and industrializing countries. However, The concerns on the industry's influences on the academia have been raised by a group of researchers such as 'Economics of science'. Against this background, this paper addresses the issues related to the relationship between the academic research and knowledge-transfer activities. Particularly, based on the 16 years' panel data of Korean academics' patent and paper outputs, the effect of patenting activities on publishing activities is investigated. Moreover, the specific context of Korean academic system as well as general characteristics of academics are considered in the analysis and discussion. According to the results, not just the publishing and patenting outputs but their productivities have been dramatically increased during the last 16 years. The main finding is that the patenting activities have a consistent positive effect on the publishing activities of the academics in the estimations of panel models. Based on these results and the discussions, some policy recommendations for university-industry collaboration are suggested.

• Journal of Chest Surgery
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• v.29 no.3
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• pp.271-277
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• 1996

In selected cases, early corrective surgery is indicated in the management of infants having large ventricular septal defects. The risk of any surgical procedure in infancy is acknowledged to be great and should be avoided whenever possible. However this greater surgical risk is justified when the patient presents with intractable congestive heart failure, severe pulmonary hypertension, marked growth retardation, and recurrent prolonged lower respiratory infections. We analyzed 31 patients with ventricular septal defect in infancy who underwent surgical correction from January 1991 through December 1994. Age ranged from 6 months to 12 months with mean age of 9.2 months. Of the thirty-one patients, 23 patients were male and 8 patients were female. Mean body weight was 7. 4kg. The most common type of ventricular septal defect was perimembraneo s (64.5%). Associated cardiac anomalies were found in 17 patients (55.8%). Mitral regurgitation was the most commonly associated cardiac anomaly (16.1 %) and followed by patent ductus arteriosus (12.9%). When cardiac catheterization data were analysed, the most common range of Qp/qs, RpiRs, Pp/ps were 2.1∼ 3.0, 1-0.25, above 0.70 respectively. Among the indications of surgical correction, there were pulmonary hypertension in 20 patients, congestive heart failure in 3 patients, intractable respiratory infection in 10 patients and growth retardation in 14 patients. The most common surgical approach and method for closure of ventricular septal defect .were right atriotomy (58%) and Dacron patch closure (94%). Postoperative complications occurred in 10 cases (32%) and overall mortality was 12.9% (4 cases). All operative deaths in this series occurred in infants under the age of 8 months and weight of 8 kilograms.

• Journal of Technology Innovation
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• v.25 no.4
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• pp.165-187
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• 2017

This study analyzed the effects of TLO's organization size, expertise, and economic compensation on technology transfer performance using the panel data of Government-Funded Research Institutes in 2013-2016. First, the size of TLO personnel and budget have a positive effect on the technology transfer performance. However, in the case of TLO manpower, the statistical significance of the effect on the number of technology transfers was only 90%, and it did not affect royalty. Second, TLO expertise has a strong impact on technology transfer performance. It shows that the number of professional license holders, such as patent attorney or a technology valuer, has a statistically significant effect on the increase of the technology transfer number and the royalty under the 99% confidence level. However, unlike expected, the size of the Ph.D. did not seem to have any effect on technology transfer performance. Finally, the economic compensation for TLO does not affect both the number of technology transfers and the royalty. It does not seem to work as an appropriate incentive system, because the absolute size of the compensation is too small. The results of the above analysis suggest that it is important to secure expertise in order for the TLO organization to play a substantial role, and it is necessary to improve the economic compensation system to attract TLOs to technology transfer.

• Journal of Digital Convergence
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• v.16 no.6
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• pp.163-173
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• 2018

The purpose of this study is to find the role of intellectual property belief between brand concepts (Symbolic vs. Functional) and brand extension. For this purpose, three parent brands (Rolex vs. Casio, Prada vs. Coach, Benz vs. Toyota) and three extension products (bracelets, shoes, vehicles) were selected as stimulants through focus group interviews and pre-tests. 296 sample data across the country were collected and the final analysis was conducted with 290 respondents except for the inappropriate respondents by SPSS 21.0. The results of this study confirm that the trademark meditates the relationship between belief brand concepts and brand extension and thinking style of consumers meditated-moderates between belief brand concepts and brand extension. The results of this study are based on implication that intellectual property belief induce consumers positive reactions on brand extension and that the acquisition and utilization of IPRs bring corporate's continuous growth and enhance the corporate brand value.