• Journal of Korea Water Resources Association
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• v.46 no.11
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• pp.1041-1052
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• 2013

In this study, we estimate parameters of a distributed hydrologic model, GRM (grid based rainfall-runoff model), using a model-independent parameter estimation tool, PEST. We implement auto calibration of model parameters such as initial soil moisture, multipliers of overland roughness and soil hydraulic conductivity in the Geumho River Catchment and the Gamcheon Catchment using radar rainfall estimates and ground-observed rainfall represented by Thiessen interpolation. Automatic calibration is performed by GRM-MP (multiple projects), a modified version of GRM without GUI (graphic user interface) implementation, and "Parallel PEST" to improve estimation efficiency. Although ground rainfall shows similar or higher cumulative amount compared to radar rainfall in the areal average, high spatial variation is found only in radar rainfall. In terms of accuracy of hydrologic simulations, radar rainfall is equivalent or superior to ground rainfall. In the case of radar rainfall, the estimated multiplier of soil hydraulic conductivity is lower than 1, which may be affected by high rainfall intensity of radar rainfall. Other parameters such as initial soil moisture and the multiplier of overland roughness do not show consistent trends in the calibration results. Overall, calibrated parameters show different patterns in radar and ground rainfall, which should be carefully considered in the rainfall-runoff modelling applications using radar rainfall.

• International Commerce and Information Review
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• v.18 no.3
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• pp.181-201
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• 2016

In this study, transaction cost approach was applied to analysis on direct export determinants of SMEs by using key attributes of transactions, asset specificity, environmental uncertainty, frequency and marketing capability, with a parameter of opportunism. Typical Transaction Cost Analysis theory explains that when transaction cost with business channels(whether it is for buy or sell) increase, the firms integrate the channels. So it is a choice made by firms regarding direct versus indirect channels. The theory was extended to a model of choice of institutional form of direct or indirect export by a norm of opportunism in this empirical study. The survey result showed that lower level of asset specificity and marketing capability or higher level of environmental uncertainty were likely to expose indirect exporters to higher level of opportunism of direct exporter. And we also saw that indirect exporters were likely to choose direct export chanel when opportunism of exporters was higher. From the standpoint of theory, we can say that the basic propositions of the Transaction Cost Analysis, except the attribute of frequency, are supported. This study result could provide a profiling of target business areas and firms for government's policy on direct export promotion of SMEs.

• Ecology and Resilient Infrastructure
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• v.3 no.1
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• pp.35-45
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• 2016

The correlation relationships and their corresponding equations between the geomorphological parameters and the Soil Water Assessment Tool (SWAT) model parameters by Sequential Uncertainty Fitting - version 2 (SUFI-2) algorithm of SWAT Calibration and Uncertainty Programs (SWAT-CUP) were developed at the Seom-river experimental watershed. The parameters of the SWAT model at the Soksa-river experimental watershed were estimated by the developed equations. The SWAT model parameters were estimated by SUFI-2 algorithm of SWAT-CUP with rainfall-runoff data from the Soksa-river experimental watershed from 2000 to 2007. Rainfall-runoff simulation of the SWAT model was carried out at the Soksa-river experimental watershed from 2000 to 2007 for the applicability of the estimated parameters by the developed equations. The root mean square errors (RMSE) between the observed and the simulated rainfall-runoffs using the estimated parameters by developed equations of correlation analysis and the optimum parameters by SUFI-2 of SWAT-CUP were $1.09m^3/s$ and $0.93m^3/s$ respectively at the Soksa-river experimental watershed from 2000 to 2007. Therefore, it is considered that the parameter estimation of the SWAT model by the geomorphological characteristics parameters has applicability.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.799-805
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• 2016

Background: There is no standard treatment for patients with platinum-resistant or refractory epithelial ovarian cancer. Single agent chemotherapies have evidence of more efficacy and less toxicity than combination therapy. Most are very expensive, with appreciable toxicity and minimal survival. Since it is difficult to make comparison between outcomes, economic analysis of single-agent chemotherapy regimens and best supportive care may help to make decisions about an appropriate management for the affected patients. Objective: To evaluate the cost effectiveness of second-line chemotherapy compared with best supportive care for patients with platinum-resistant or refractory epithelial ovarian cancer. Materials and Methods: A Markov model was used to estimate the effectiveness and total costs associated with treatments. The hypothetical patient population comprised women aged 55 with platinum-resistant or refractory epithelial ovarian cancer. Four types of alternative treatment options were evaluated: 1) gemcitabine followed by BSC; 2) pegylated liposomal doxorubicin (PLD) followed by BSC; 3) gemcitabine followed by topotecan; and 4) PLD followed by topotecan. Baseline comparator of alternative treatments was BSC. Time horizon of the analysis was 2 years. Health care provider perspective and 3% discount rate were used to determine the costs of medical treatment in this study. Quality-adjusted life-years (QALY) were used to measure the treatment effectiveness. Treatment effectiveness data were derived from the literature. Costs were calculated from unit cost treatment of epithelial ovarian cancer patients at various stages of disease in King Chulalongkorn Memorial Hospital (KCMH) in the year 2011. Parameter uncertainty was tested in probabilistic sensitivity analysis by using Monte Carlo simulation. One-way sensitivity analysis was used to explore each variable's impact on the uncertainty of the results. Results: Approximated life expectancy of best supportive care was 0.182 years and its total cost was 26,862 Baht. All four alternative treatments increased life expectancy. Life expectancy of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 0.510, 0.513, 0.566, and 0.570 years, respectively. The total cost of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 113,000, 124,302, 139,788 and 151,135 Baht, respectively. PLD followed by topotecan had the highest expected quality-adjusted life-years but was the most expensive of all the above strategies. The incremental cost-effectiveness ratios (ICER) of gemcitabine followed by BSC, PLD followed by BSC, gemcitabine followed by topotecan and PLD followed by topotecan was 344,643, 385,322, 385,856, and 420,299 Baht, respectively. Conclusions: All of the second-line chemotherapy strategies showed certain benefits due to an increased life-year gained compared with best supportive care. Moreover, gemcitabine as second-line chemotherapy followed by best supportive care in progressive disease case was likely to be more effective strategy with less cost from health care provider perspective. Gemcitabine was the most cost-effective treatment among all four alternative treatments. ICER is only an economic factor. Treatment decisions should be based on the patient benefit.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.2 s.72
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• pp.171-185
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• 2006

A sophisticated reliability analysis method is proposed to evaluate the reliability of real nonlinear complicated dynamic structural systems excited by short duration dynamic loadings like earthquake motions by intelligently integrating the response surface method, the finite element method, the first-order reliability method, and the iterative linear interpolation scheme. The method explicitly considers all major sources of nonlinearity and uncertainty in the load and resistance-related random variables. The unique feature of the technique is that the seismic loading is applied in the time domain, providing an alternative to the classical random vibration approach. The four-parameter Richard model is used to represent the flexibility of connections of real steel frames. Uncertainties in the Richard parameters are also incorporated in the algorithm. The laterally flexible steel frame is then reinforced with reinforced concrete shear walls. The stiffness degradation of shear walls after cracking is also considered. The applicability of the method to estimate the reliability of real structures is demonstrated by considering three examples; a laterally flexible steel frame with fully restrained connections, the same steel frame with partially restrained connections with different rigidities, and a steel frame reinforced with concrete shear walls.

• Journal of the Korean Geotechnical Society
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• v.18 no.2
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• pp.51-64
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• 2002

Observational results of ground movement during the construction were very different from those predicted during the analysis of design step because of the uncertainty of the numerical analysis modelling, the soil parameter, and the condition of a construction field, etc., however accurately numerical analysis method was applied for prediction of ground movement per the excavation step. Therefore, the management system through the construction field measurement should be achieved for grasping the situation during the excavation. Until now, the measurement system restricted by 'Absolute Value Management system'analyzing only the stability of present step has been executed. So, it was difficult to expect the prediction of ground movement fur the next excavation step. In this situation, this study developed 'The Management system TOMAS-EXCAV'consisted of 'Absolute value management system'analyzing the stability of present step and 'Prediction management system'expecting the ground movement of next excavation step and analyzing the stability of next excavation step by 'Back Analysis'. TOMAS-EXCAV could be applied to all the uncertainty of earth retaining structures analysis by connecting 'Forward analysis program'and 'Back analysis program'and optimizing the main design variables using SQP-MMFD optimization method through measurement results. The applicability of TOMAS-EXCAV was confirmed by back analysis selecting two earth retains construction fields.

• Journal of the Korean GEO-environmental Society
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• v.10 no.7
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• pp.7-14
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• 2009

The correlation equation empirically proposed to obtain compression indexes has been proposed to conveniently obtain the value using the soil parameter that can be obtained through simple tests when the number of time of consolidation testing is low or the distribution is large but most of the analyzed regions are limited to certain regions abroad or in the country and multiple data were integrated for use in many cases, thus it is not very reasonable to apply it. Therefore, to establish a new design method considering the uncertainty of the ground, it was selected the Kwangyang port area of which the data have been collected recently thus are relatively more reliable as the subject region of the study in order to maximally reduce the uncertainty of test data. After performing the verification of the normality of the consolidation test data obtained from the selected region and the transformation of variables, a prediction formula was proposed through the regression model with the transformed variables and the proposed regression model with transformed variables was compared with existing empirical equations to verify the suitability of the proposed model formula. After analyzing, it was confirmed that the coefficient of determination was increased after the Box-Cox variable transformation, thus the explanatory power was being enhanced and through the root-mean-square-error method, it was confirmed that the proposed model formula showed the most closed value to the test value.

• Journal of Korea Water Resources Association
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• v.42 no.7
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• pp.547-558
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• 2009

General reliability assessment of levees embankment is performed with safety factors for rainfall characteristics and hydrologic and hydraulic parameters, based on the results of deterministic analysis. The safety factors are widely employed in the field of engineering handling model parameters and the diversity of material properties, but cannot explain every natural phenomenon. Uncertainty of flood analysis and related parameters by introducing stochastic method rather than deterministic scheme will be required to deal with extreme weather and unprecedented flood due to recent climate change. As a consequence, stochastic-method-based measures considering parameter uncertainty and related factors are being established. In this study, a variety of dimensionless cumulative rainfall curve for typhoon and monsoon season of July to September with generation method of stochastic temporal variation is generated by introducing Monte Carlo method and applied to the risk assessment of levee embankment using reliability index. The result of this study reflecting temporal and regional characteristics of a rainfall can be used for the establishment of flood defence measures, hydraulic structure design and analysis on a watershed.

• Korean Journal of Construction Engineering and Management
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• v.12 no.3
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• pp.121-130
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• 2011

Real option values of early termination payment for selected BTO PPI projects are studied using binomial models. Two cases of early termination payments are considered; an option with the condition of private participants' default, and an option without the condition. Values vary depending upon parameter values such as revenues, costs, discount rates, debt ratio, and volatility of revenues. For selected projects, the option values without the default condition are estimated as 1%~7% of total project costs, whereas the option values with the default condition are estimated as 0%~1.89% of total project cost. When actual revenues differ from the forecasted revenues, apparently the option values deviate from the values based upon the forecasted revenues. When actual revenues fall short of the forecasted revenues, the option values increase by a large amount whereas the option values decrease by a small amount in the opposite case. This implies that the option values can be quite bigger than the values based upon the forecasted revenue especially when the revenue forecast uncertainty is large. This study is expected to play an important role in improving the early termination payment option policy of the government in PPI projects in Korea.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.8
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• pp.751-758
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• 2015

Mathematical models are actively used to reduce the experimental expenses required to understand physical phenomena. However, they are different from real phenomena because of assumptions or uncertain parameters. In this study, we present a calibration and validation method using a paper helicopter and statistical methods to quantify the uncertainty. The data from the experiment using three nominally identical paper helicopters consist of different groups, and are used to calibrate the drag coefficient, which is an unknown input parameter in both analytical models. We predict the predicted fall time data using probability distributions. We validate the analysis models by comparing the predicted distribution and the experimental data distribution. Moreover, we quantify the uncertainty using the Markov Chain Monte Carlo method. In addition, we compare the manufacturing error and experimental error obtained from the fall-time data using Analysis of Variance. As a result, all of the paper helicopters are treated as one identical model.