• 한국식물생명공학회:학술대회논문집
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• 한국식물생명공학회 2002년도 춘계학술대회
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• pp.19-25
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• 2002

Biotechnology in the 21st century will be driven by three emerging technologies: genomics, high-throughput biology, and bioinformatics. These technologies are complementary to one another. A large number of economically important crops are currently subjected to whole genome sequencing. Functional genomics for determining the functions of the genes comprising the given plant genome is under progress by using various means including phenotyping data from transgenic mutants, gene expression profiling data from DNA microarrays, and metabolic profiling data from LC/mass analysis. The aim of plant molecular breeding is shifting from introducing agronomic traits such as herbicide and insect resistance to introducing quality traits such as healthful oils and proteins, which will lead to improved and nutritional food and feed products. Plant molecular breeding is also expected to aim to develop crops for producing human therapeutic and industrial proteins.

• Journal of Korean Neurosurgical Society
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• 제63권4호
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• pp.427-432
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• 2020

Three randomized control trials (RCTs), published in 2013, investigated efficacy of mechanical thrombectomy in large vessel occlusions and did not show better results compared to intravenous (IV) recombinant tissue-type plasminogen activator (tPA) alone. However, most clinicians treating stroke consider mechanical thrombectomy as the standard treatment rather than using IV tPA alone. This paradigm shift was based on five RCTs investigating efficacy of mechanical thrombectomy in acute ischemic stroke conducted from 2010 to 2015. They demonstrated that mechanical thrombectomy was effective and safe in acute ischemic stroke with anterior circulation occlusion when performed within 6 hours of stroke onset. There are four reasons underlying the different results observed between the trials conducted in 2013 and 2015. First, the three RCTs of 2013 used low-efficiency thrombectomy devices. Second, the three RCTs used insufficient image selection criteria. Third, following the initial presentation at the hospital, reperfusion treatment required a long time. Fourth, the three RCTs showed a low rate of successful recanalization. Time is the most important factor in the treatment of acute ischemic stroke. However, current trends utilize advanced imaging techniques, such as diffusion-weighted imaging and multi-channel computer tomographic perfusion, to facilitate the detection of core infarction, penumbra, and collateral flows. These efforts demonstrate that patient selection may overcome the barriers of time in specific cases.

• 디지털산업정보학회논문지
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• 제8권2호
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• pp.189-198
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• 2012

The demand of smart phone that recently came into spotlight as a new media is sharply increasing not only in Korean market but also in worldwide market but the academic study on this is still in the beginning stage. Hence, it would be a well-timed topic for discussion to make a systematic investigation and analysis. The technology acceptance model used in this study as a theoretical frame can set various external factors in introduction of new information technology as variables. This study made an assumption that such external factors would influence on perceived usefulness, easiness and amusement and such perceived awareness would make an impact on user's satisfaction and repurchase intention. This study proposed an empirical model in order to find out the recommendations and repurchase intention for new media, smart phone. This study model was validated to be very effective model that can explain more concretely and systematically for repurchase of smart phone. In conclusion, this paper illustrates a paradigm shift in smart environment to smart device manufacturers under fierce competition in the world market as well as various analysis results on consumer's use patterns according to such paradigm shift, which shall be utilized as useful information when establishing a marketing strategy for smart phone.

• 농촌지도와개발
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• 제7권2호
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• pp.279-288
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• 2000

Agricultural extension services in Korea are faced with increasing demands for more efficient production and managerial technology according to globalization and free trade system. At the same time, three steps of organizational restructuring in 1998 and 1999 resulted in decreased number of organization and manpower, thus, resulting confusion in implementing extension services. To cope with the international and national challenges, Korean agricultural extension services should try paradigm shift including the followings; 1. To establish identity of agricultural extension services in Korea through making laws and regulations in terms of concept, roles, principles. implementation and methods. 2. To implement vitalizations plan through enhancement of national extension service such as food production. raising local specialty products for domestic consumption and producing strategic agricultural products for export. expanding capability of rural women, increasing opportunity for management consultation, supporting digital technology information, and promoting morale and capability of extension educators. 3. To reform agricultural extension system through adjusting the functions of extension service of the Rural Development Administration, regionalizing city and county extension center to provincial level, and changing the status of directors of extension centers from city /county to national government.

• 가정과삶의질연구
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• 제20권6호
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• pp.37-48
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• 2002

Mid of 1980s witnessed the beginning of a new trend regarding the elderly as the Third Age Group, which is capable of positive selection for their later life. These changes are caused not only by the rising cost of caring them as the dependent to the society, but also by paradigm shift from the clinical and biomedical model to political economy and critical gerontology. The paradigm shift is based on the social constructionism as a perspective on the later life. In this communication the development of social constructionism is reviewed as an approach on the living environment for later life through literature survey. Emphases were made on the anti-ageism instead of ageism in the analysis of the social constructionism perspective for living environment in later life. Individual practice, influencing the practice of others, influencing agency policy, and developing theory were addressed and emphasized for the practice of anti-ageism. This study found the importance of the development of the social constructionism perspective on the study and practice regarding living environment for ‘the Third Age’ in Korean situation.

• Journal of Plant Biotechnology
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• 제29권3호
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• pp.145-150
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• 2002

Biotechnology in the 21st century will be driven by three emerging technologies: genomics, high-throughput biology, and bioinformatics. These technologies are complementary to one another. A large number of economically important crops are currently subjected to whole genome sequencing. Functional genomics for determining the functions of the genes comprising the given plant genome is under progress by using various means including phenotyping data from transgenic mutants, gene expression profiling data from DNA microarrays, and metabolic profiling data from LC/mass analysis. The aim of plant molecular breeding is shifting from introducing agronomic traits such as herbicide and insect resistance to introducing quality traits such as healthful oils and proteins, which will lead to improved and nutritional food and feed products. Plant molecular breeding is also expected to aim to develop crops for producing human therapeutic and industrial proteins.

• 의학교육논단
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• 제15권1호
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• pp.39-45
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• 2013

The recent medical education paradigm shift from teacher-centered to student-centered education, has led to a concentration on students' performance and competency. This means that a physician should be able to provide adequate health care in any real medical treatment situation. In order to reflect such a paradigm shift, The Catholic University of Korea School of Medicine launched a new curriculum in 2009 that emphasizes students' performance and competency-based education, known as "outcome-based education." In outcome-based education, the educational process is determined by the desired outcome, signifying the detailed competency that a graduating student should have. Thus, in outcome-based education, we should first determine the competency that results from adequate training and education, followed by specific teaching and learning strategies, methods, and assessment. This paper reviews how The Catholic University School of Medicine developed its new curriculum according to the development steps of outcome-based education.

• 한국의료질향상학회지
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• 제27권1호
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• pp.2-9
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• 2021

Patient safety remains one of the most important health care issues in Korea. To improve patient safety, we have introduced concepts from the field of safety science such as the Swiss cheese model, and adopted several methodologies previously used in other industries, including incident reporting systems, root cause analysis, and failure mode and effects analysis. This approach has enabled substantial progress in patient safety to be made through undertaking patient safety improvement activities in hospitals that are systems-based, rather than individual-based. However, these methods have the shared limitation of focusing on negative consequences of patient safety. Therefore, the paradigm shift from Safety I to Safety-II in safety science becomes the focus of our discussion. We believe that Safety-II will complement, rather than replace, Safety-I in the discipline of patient safety. In order to continuously advance patient safety practices in Korea, it is necessary that Korea keeps abreast of the recent global trends and development in safety science. In addition, more focus should be placed on testing the feasibility of new patient safety approaches in real-world situations.

• 한국물환경학회지
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• 제39권1호
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• pp.76-86
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• 2023

We are on the verge of paradigm shift for the design and operation of our urban water systems from treatment- and efficiency-based to recirculation- and sustainability-based. One of the most frequently suggested alternatives to embody this paradigm shift is to decentralize the currently highly centralized urban water infrastructure. However, claims for water infrastructure decentralization are often criticized due to poor economic feasibility, unstable performance, and unprofessional operation and maintenance. The current study critically reviews the literature to discuss the technical advancement needs to overcome such challenges. Firstly, decentralized water infrastructure was briefly defined and the rationale for the proposal of its introduction to the next-generation urban water systems was laid down. The main discussion focused on the following water technologies, which require special attention when working with decentralized water infrastructure: i) material collection, storage, and transport; ii) easily scalable water treatment; iii) sensor, information, and communications; and iv) system optimization. The principles, current development status, and challenges were discussed for each of the water technologies. The discussion on the water technologies has enabled the identification of future research needs for their application to the next-generation urban water systems which will be designed following decentralized water infrastructure. This paper will significantly improve the current understanding on water infrastructure decentralization and provides insight on future direction of water technology development.

• 한국산업정보학회논문지
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• 제15권1호
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• pp.85-94
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• 2010

e-Learning으로 대변되는 교육의 변화는 교육환경의 기술적인 측면뿐만 아니라 패러다임 자체를 바꾸어 놓고 있다. e-Learning 환경에서의 사용자는 시스템 사용자뿐만 아니라 학습자의 역할을 동시에 가지고 있기 때문에 이런 복잡한 현상을 설명하기 위해서는 보다 포괄적인 시각이 필요하다고 판단된다. 본 연구에서는 포괄적인 시각을 연구하기에 앞서 학습자의 동기 유발에 초점을 두고 학습 성과를 향상시킬 수 있는 방안을 플로우 이론을 이용하여 제시하고자 한다. 연구 결과 첫째, 플로우의 구성 요소인 내재된 흥미와 주의집중은 종속 변수인 학습 성과에 유의적인 영향을 미치고 있으며, 특히 내재된 흥미가 주의집중보다 더 중요한 요인으로 밝혀졌다. 둘째, 내재된 흥미에 영향을 미치는 요인은 정보 품질과 숙련도로 나타났으며, 셋째, 주의집중에 영향을 미치는 요인은 인지된 사용용이성, 숙련도, 컴퓨터 자기효능감으로 나타났다.