• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.677-682
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• 2018

The relationship-type research and development (R&D) portfolio is a method for selecting core technologies based on their unique purposes and characteristics when the criteria for selecting them are independent. This study presents a relationship-type R&D portfolio method as a way to derive core technologies, and describes the methodology by dividing it into three steps: 1) analyze the relationships between selection criteria and analytical indicators, 2) form a portfolio matrix that best matches each selection criteria, and 3) derive the core technologies. In this study, the relationships between four selection criteria for selecting core technologies and the analytical indicators for identifying the technology level, economics, and the technology itself, are written in a table with HoQ. Based on the relationship table, analytical indicators to be considered were derived to satisfy each selection criterion, and the derived analytical indicators and the selected technologies were constructed with two axes in the portfolio matrix. The satisfied portfolio, P0, that satisfies all four criteria, and the portfolio, P1~P4, that satisfies selection criteria based on the unique characteristics of the four criteria, were constructed, and core technologies derived. The selected core technologies can be utilized in selecting a core area against the future security environment through a process like key word analysis based on the specifications.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.93-102
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• 2022

Purpose : The purpose of this study was to analyze the change in thickness of transvers abdominis, internal oblique, and external oblique when virtual reality based ring fit adventure is applied to young adults in order to investigate the effect of ring fit adventure on core stabilization. Methods : 30 subjects participated in the experiment. Subjects were randomly assigned to two groups. 15 subjects performed ring fit adventure core exercise (experimental group) and 15 subjects bridge and dead bug exercise (control group). The ring fit adventure core exercise program consists of 6 types, 1) bow pull, 2) overhead lunge twist, 3) pendulum bend, 4) seated ring raise, 5) plank, 6) warrior III pose. Each exercise was performed for 5 minutes, for a total of 30 minutes. The bridege and dead bug exercise were performed for 15 minutes each for a total of 30 minutes. All interventions were performed 3 times a week for 4 weeks. Thickness of the abdominal muscles was measured with a ultrasound. The paired t-test was used to compare the thickness of the transverse abdominis, internal oblique, and external oblique before and after intervention, and the comparison between groups was analyzed using the independent t-test. Results : As a result, in the experimental group, thickness of transverse abdominis and internal oblique increased significantly (p<.05), but external oblique decreased significantly (p<.05), and in the control group, thickness of transverse abdominis, internal oblique, and external oblique increased significantly (p<.05). There was a significant difference in external oblique in the difference between groups (p<.05). Conclusion : These study results showed that core exercise using ring fit adventure can reduce external oblique and increased selective muscle activity of transverse abdominis and internal oblique of the deep abdominal muscles, so it is meaningful as an effective intervention for core stabilization.

• Journal of International Academy of Physical Therapy Research
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• v.3 no.1
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• pp.378-382
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• 2012

The purpose of this study effectiveness of core strengthening exercise programs on symmetric double limb support and balance ability for elderly. The subjects that 30 persons between the ages of 65~80 elderly participated were divided into two groups randomly for 8 weeks. Tetrax interactive balance system and Berg's balance scale were used to assess support and stability. Paired t-tests were used to evaluate the changes before and after intervention. The difference between the groups was compared using an independent t-test. The experimental group showed significantly increase weight support, stability, balance(p<.05). However, the control group not showed significantly increase weight support, stability, balance(p>.05). In a variation, experimental and control groups showed significantly increased rate of weight support, stability, balance(p<.05). Consequently, core strengthening exercise program should be considered as a therapeutic method for the elderly to improve the balance ability and effectiveness on falls.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.293-300
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• 2018

Objective: This study observed the effects of cooking method and final core temperature on cooking loss, lipid oxidation, aroma volatiles, nucleotide-related compounds and aroma volatiles of Hanwoo brisket (deep pectoralis). Methods: Deep pectoralis muscles (8.65% of crude fat) were obtained from three Hanwoo steer carcasses with $1^+$ quality grade. Samples were either oven-roasted at $180^{\circ}C$ (dry heat) or cooked in boiling water (moist heat) to final core temperature of $70^{\circ}C$ (medium) or $77^{\circ}C$ (well-done). Results: Boiling method reduced more fat but retained more moisture than did the oven roasting method (p<0.001), thus no significant differences were found on cooking loss. However, samples lost more weight as final core temperature increased (p<0.01). Further, total saturated fatty acid increased (p = 0.02) while total monounsaturated fatty acid decreased (p = 0.03) as final core temperature increased. Regardless the method used for cooking, malondialdehyde (p<0.01) and free iron contents (p<0.001) were observed higher in samples cooked to $77^{\circ}C$. Oven roasting retained more inosinic acid, inosine and hypoxanthine in samples than did the boiling method (p<0.001), of which the concentration decreased as final core temperature increased except for hypoxanthine. Samples cooked to $77^{\circ}C$ using oven roasting method released more intense aroma than did the others and the aroma pattern was discriminated based on the intensity. Most of aldehydes and pyrazines were more abundant in oven-roasted samples than in boiled samples. Among identified volatiles, hexanal had the highest area unit in both boiled and oven-roasted samples, of which the abundance increased as the final core temperature increased. Conclusion: The boiling method extracted inosinic acid and rendered fat from beef brisket, whereas oven roasting intensified aroma derived from aldehydes and pyrazines and prevented the extreme loss of inosinic acid.

• The Journal of Korean Academy of Prosthodontics
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• v.37 no.6
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• pp.756-766
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• 1999

This study was performed to evaluate effect on color and opacity of 3 different copy-milled In-Ceram cores by glass infiltration and porcelain veneering. Color was evaluated by the $CIEL^*a^*b^*$ readings were recorded with a Colorimeter, Color difference value(${\Delta}E^*_{ab}$) was calculated and opacity was represented by the contrast ratio. The variance of each color parameter ($L^*,\;a^*,\;b^*$), color difference value, and opacity change after glass-infiltrated and after veneered with porcelain was compared. Three experimental groups were fabricated as follows. Group 1 (Alumina core) 15 Alumina blanks was infiltrated with originally marketed glass (A1) and veneered with porcelain(A1) Group 2 (modified Alumina core) : 15 Alumina blanks was infiltrated with its associated glass(S11) and veneered with porcelain(A1) Group 3 (Spinell core) : 15 Spinell blanks was infiltrated with originally developed glass(S11) and veneered with porcelain(A1). The results were as follows: 1. After glass infiltration, $L^*$ value showed decrease, $a^*$ value showed decrease only group 1(p<0.001) and $b^*$ value showed increase on group 1, increase on group 2, 3(p<0.001). 2. After porcelain veneering, $L^*$ value showed decrease(p<0.001), $a^*$ value showed increase on group 1, decrease on group 2(p<0.05) and $b^*$ value showed decrease on group 1, increase on group 2, 3 (p<0.001). 3. ${\Delta}E^*_{ab}$ between before and after glass infiltration was more than 13.77, and between after glass infiltration and after porcelain veneering more than 19.63. 4. After glass infiltration and porcelain veneering, Alumina showed the lowest $L^*,\;a^*$ value and highest $b^*$ value among 3 different groups (p<0.05). ${\Delta}E^*_{ab}$ between group 1-2, 1-3 was higher than that of group 2-3. 5. After glass infiltration, opacity showed decrease, Group 1 had the highest opacity(p<0.05), but no significant differences between group 2 and 3. Above results suggest that glass infiltration and porcelain veneering effects on color and opacity of In-Ceram core, and that modified In-Ceram Alumina uses single crowns or bridges like In-Ceram Spinell.

• The Korean Journal of Emergency Medical Services
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• v.21 no.3
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• pp.35-48
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• 2017

Purpose: The purpose of the study was to investigate the core competency of disaster management of 119 paramedics. Methods: A self-reported questionnaire was completed by 242 paramedics in C area from April 28 to May 12, 2017. The study instrument included general characteristics of the subjects (4 items), disaster experience, recognition, and preparedness (20 items), and importance and performance of disaster management core competency (24 items) by Likert 5-point scale. Data were analyzed using t-test, ANOVA, Pearson's correlation coefficient using IBM SPSS 24.0. Results: The seriousness of personal disaster was 4.02 points and the importance of disaster-related education was 4.28 points. The importance to core competency of disaster management was 4.39 points and the ability to perform core competency was 3.58 points. The seriousness of personal disaster and the importance of disaster-related education were positively correlated (r=.600, p=.000). The importance and ability to perform core competency were positively correlated (r=.389, p=.000). Conclusion: It is necessary to strengthen core competency of disaster management in paramedics who are the first defense line of disaster.

• Korean Parent-Child Health Journal
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• v.16 no.1
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• pp.37-44
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• 2013

Purpose: The purpose of this study is to analyze the effectiveness of maternity nursing education-knowledge, skills and attitude among the third year students who have completed maternity nursing, practice at the college, clinical practice and core skill practicum. Methods: This is the descriptive research to verify the effectiveness of simulation-based practice education for core skill of maternity nursing. Third year nursing students who have completed maternity nursing related theories and practice have been selected as population. Total of 202 surveys have been used for analysis. Data analysis is done by using SPSS/WIN 18.0. Results: Self-confidence of core skill in maternity nursing is experimental group 4.52 and control group 4.37 score (p<.05). Performance competence in childbirth care is experimental group 4.53 and control group 4.35 score (p<.05). The students who have maternity nursing related clinical practice and core skill practicum experience show high core skill evaluation score. Conclusion: Therefore, it is recommended that current maternity nursing core skill curriculum should be reviewed and improved, and the students should be provided variety of simulation techniques to gain essential knowledge and core nursing skills.

• Bulletin of the Korean Chemical Society
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• v.27 no.2
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• pp.266-272
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• 2006

Three-dimensional quantitative structure-activity relationship (3D-QSAR) models were developed for 67 molecules of 2-amino-benzothiazole-6-anilide derivatives against lymphocyte-specific protein tyrosine kinase (P56 LCK). The molecular field analysis (MFA) and receptor surface analysis (RSA) were employed for QSAR studies and the predictive ability of the model was validated by 15 test set molecules. Structure-based investigations using molecular docking simulation were performed with the crystal structure of P56 LCK. Good correlation between predicted fitness scores versus observed activities was demonstrated. The results suggested that the nature of substitutions at the 2-amino and 6-anilide positions were crucial in enhancing the activity, thereby providing new guidelines for the design of novel P56 LCK inhibitors.

• Journal of Powder Materials
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• v.31 no.3
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• pp.226-235
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• 2024

InP quantum dots (QDs) have attracted researchers' interest due to their applicability in quantum dot light-emitting displays (QLED) or biomarkers for detecting cancers or viruses. The surface or interface control of InP QD core/ shell has substantially increased quantum efficiency, with a quantum yield of 100% reached by introducing HF to inhibit oxide generation. In this study, we focused on the control of bandgap energy of quantum dots by changing the Zn/(In+Zn) ratio in the In(Zn)P core. Zinc incorporation can change the photoluminescent light colors of green, yellow, orange, and red. Diluting a solution of as-synthesized QDs by more than 100 times did not show any quenching effects by the Förster resonance energy transfer phenomenon between neighboring QDs.

• Bulletin of the Korean Chemical Society
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• v.29 no.8
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• pp.1539-1544
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• 2008

A polymeric micelle, based on the poly(benzyl-L-histidine)-b-poly(ethylene glycol) (polyBz-His-b-PEG) diblock copolymer, was designed as a tumor-specific targeting carrier. The micelles (particle size: 67-80 nm, critical micelle concentration (CMC); 2-3 $\mu$g/mL) were formed from the diafilteration method at pH 7.4, as a result of self-assembly of the polyBz-His block at the core and PEG block on the shell. Removing benzyl (Bz) group from polyBz-His block provided pH-sensitivity of the micellar core; the micelles were physically destabilized in the pH range of pH 7.4-5.5, depending on the content of the His group free from Bz group. The ionization of His group at a slightly acidic pH promoted the deformation of the interior core. These pHdependent physical changes of the micelles provide the mechanism for pH-triggering anticancer drug (e.g., doxorubicin: DOX) release from the micelle in response to the tumor’s extracellular pH range (pH 7.2-6.5).