• Bulletin of the Korean Chemical Society
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• v.20 no.9
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• pp.1073-1077
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• 1999

CRAMP, a 37-amino acid cationic antimicrobial peptide was recently deduced from the cDNA cloned from mouse femoral marrow RNA. In order to investigate the structure-activity relationship and functional region of CRAMP, CRAMP and its 18-mer overlapping peptides were synthesized by the solid phase method. CRAMP showed broad spectrum antibacterial activity against both Gram-positive and Gram-negative bacterial strains (MIC: 3.125-6.25 μM) but had no hemolytic activity until 50 μM. CRAMP was found to have a potent anticancer activity (IC50: 12-23 μM) against two human small cell lung cancer cell lines. Furthermore, CRAMP was found to display faster bactericidal rate in B. subtilis rather than E. coli in the kinetics of bacterial killing. Among 18-meric overlapping fragment peptides, only CRAMP (16-33) displayed potent antibacterial activity (MIC: 12.5-50 μM) against several bacteria with no hemolytic activity. Circular dichroism (CD) spectra anal-ysis indicated that CRAMP and its analogues will form the amphipathic α-helical conformation in the cell membranes similar to other antimicrobial peptides, such as cecropins and magainins.

• Steel and Composite Structures
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• v.51 no.5
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• pp.575-586
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• 2024

Steel arch supports are used in mines and underground structures to provide stability. Most of the supports are made up of overlapping arches. They can behave either yieldingly or unyieldingly. If the normal force at any point of overlapping equals the slip resistance, the slide occurs. This paper presents a solution procedure for determining the load-carrying capacity of steel arch supports in the yielding implementation. This solution considers the effects of several significant elements, including differing materials and the number of clamps in yielding friction joints. The direct stiffness method is applied. The solution contains geometric, physical, and structural nonlinearity. The results obtained from numerical modeling using the provided procedure are compared to laboratory tests conducted at GIG Katowice in 2012. They show a good correlation with previously collected data from equivalent laboratory conditions.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2000.11a
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• pp.28-31
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• 2000

We describe a hidden Markov model, HMMTIR, for general protein sequence based on the I-sites library of sequence-structure motifs. Unlike the linear HMMs used to model individual protein families, HMMSTR has a highly branched topology and captures recurrent local features of protein sequences and structures that transcend protein family boundaries. The model extends the I-sites library by describing the adjacencies of different sequence-structure motifs as observed in the database, and achieves a great reduction in parameters by representing overlapping motifs in a much more compact form. The HMM attributes a considerably higher probability to coding sequence than does an equivalent dipeptide model, predicts secondary structure with an accuracy of 74.6% and backbone torsion angles better than any previously reported method, and predicts the structural context of beta strands and turns with an accuracy that should be useful for tertiary structure prediction. HMMSTR has been incorporated into a public, fully-automated protein structure prediction server.

• Smart Structures and Systems
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• v.2 no.2
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• pp.171-188
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• 2006

This paper deals with damage detection using active Lamb waves. The wavelet transform and empirical mode decomposition methods are discussed for measuring the Lamb wave's arrival time of the group velocity. An experimental system to diagnose the damage in the composite plate is developed. A method to optimize this system is also given for practical applications of active Lamb waves, which involve optimal arrangement of the piezoelectric elements to produce single mode Lamb waves. In the paper, the single mode Lamb wave means that there exists no overlapping among different Lamb wave modes and the original Lamb wave signal with the boundary reflection signals. Based on this optimized PZT arrangement method, five damage localizations on different plates are completed and the results using wavelet transform and empirical mode decomposition methods are compared.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.7
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• pp.1815-1830
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• 2012

Existing R-tree that is based on a variety of outdoor-based techniques to manage moving objects have been investigated. Due to the different characteristics of the indoor and outdoor, it is difficult to management of moving object using existed methods in indoor setting. We propose a new index structure called ACII(adaptive Cell-based index for Indoor moving objects) for Indoor moving objects. ACII is Cell-based access structure adopting an overlapping technique. The ACII refines cells adaptively to handle indoor regional data, which may change its locations over time. The ACII consumed at most 30% of the space required by R-tree based methods, and achieved higher query performance compared with r-tree based methods.

• Proceedings of the KSRS Conference
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• 2008.10a
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• pp.262-265
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• 2008

We design level 1 traffic thematic map for common data structure. Level 1 means the road that can passing cars. If public office and private company use this form, they can save amount of money from overlapping update. And widely use of traffic analysis, navigation and traffic information system. For design common data structure we compared several data structure(traffic thematic map, ITS standard node/link, Car navigation map), and generalization these characteristic data. After generalization we considered about application parts. It can use of public part(traffic analysis, road management, accident management) and private part(car navigation, map product, marketing by variable analysis) etc.

• Journal of the Korea Fashion and Costume Design Association
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• v.6 no.2
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• pp.15-20
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• 2004

These days are referred to as 'the times of textile fashion,' owing to the emphasis on textile design in the fashion industry. Accordingly, apparel companies have increased their interests in developing new types of textiles to overcome the limits of style and silhouette. Now the ultra-fashion of textile, a new way of process and design development, is given much more attention. A Moire interference pattern has a longer wavy circle of interference, an effect of intensity interference, than one made by piling more than one reflecting plate or transmitting plate. Till now, Moire interference patterns have been used to confirm scientific theory and to measure the structure of a body or a subject in areas such as physics and medical science. Work has also been done on the Moire interference effects on TV screens said to cause dizziness and eye strain. This study focuses on the new types of textiles by creating the appearance of the Moire phenomena. Contrary to the present usual stationary patterns of textiles, it is a varying pattern according to the different gratings, different angles, piling gratings, and the movements of the human bodies. In the preceding study, we observed Moire fringes formed by overlapping two different or same kinds of gratings such as parallel line gratings, square gratings, conic gratings and semicircular gratings and tried to find a promising possibility of new textiles through the method of clothes design simulation.

• Journal of Korean Institute of Industrial Engineers
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• v.34 no.3
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• pp.344-354
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• 2008

The ITA meta-model descriptions being promoted by Korean government was developed to build information technology architecture for applications in public institutions. However, the application of this ITA meta-model is not easy because of the complexity and overlapping between classes and attributes which reside in the ITA meta-models. Additionally, the National Defense Architecture is planned for development using the MND-AF. Since the National Defense Architecture must align with the Government ITA for interoperability and consistency, it is crucial the differences in the meta-models between MND-AF and Government ITA must be resolved. This study presents the trade-off results between the meta-models of MND-AF and Government ITA. It also proposes a set of tailored meta-models for use with the National Defense architecture development. The tailored meta-models use an ERA (Element, Relationship, Attribute) data structure that decreases complexity and eliminates the overlapping between classes and attributes.

• Korean Journal of Remote Sensing
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• v.23 no.3
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• pp.211-219
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• 2007

Building extraction is one of the essential issues for 3D city modelling. In recent years, high-resolution satellite imagery has become widely available and it brings new methodology for urban mapping. In this paper, we have developed a semi-automatic algorithm to determine building heights from monoscopic high-resolution satellite data. The algorithm is based on the analysis of the projected shadow and actual shadow of a building. Once two roof comer points are measured manually, the algorithm detects (rectangular) roof boundary automatically. Then it estimates a building height automatically by projecting building shadow onto the image for a given building height, counting overlapping pixels between the projected shadow and actual shadow, and finding the height that maximizes the number of overlapping pixels. Once the height and roof boundary are available, the footprint and a 3D wireframe model of a building can be determined. The proposed algorithm is tested with IKONOS images over Deajeon city and the result is compared with the building height determined by stereo analysis. The accuracy of building height extraction is examined using standard error of estimate.

• Communications for Statistical Applications and Methods
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• v.27 no.6
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• pp.649-673
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• 2020

This paper makes a theoretical contribution by providing clear and detailed derivation of economic agents' decision problems including elastic labor supply in Gertler's overlapping generation (OLG) model. We apply the model to the Korean economy by calibration based on Korean economic data. It also analyzes the impact of current social issues such as aging and extension of retirement age, on the Korean economy in a long-run equilibrium. Subsequently, we also discuss the implications of the analysis. Aging has prolonged the period of retirement; therefore, population structure changes by the increase in the proportion of retirees, the total consumption-to-GDP ratio decreases, and capital stock increases due to reduced propensity to consume out of wealth in preparation for an individual's retirement life. The implementation of retirement age extension increases the proportion of retirees relatively less and alleviates fluctuations in labor supply and the share of financial assets for both economic agents. However, the decrements in consumption-to-GDP ratio is larger than before, and this leads to a larger rise in the capital stock compared to when there is only an aging effect.