• Journal of the Korean Society of Physical Medicine
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• v.18 no.4
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• pp.29-35
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• 2023

PURPOSE: High-intensity physical therapy may help improve some gross motor developmental delays through an increased treatment frequency. This study describes an increase in physical therapy frequency and intensity over an eight-week time frame for a child with a rare genetic neurodevelopmental disorder. METHODS: A single-subject research was performed. The subject was a nine-year-old boy with MECP2 Duplication Syndrome. The outcome measure consisted of one time before and after the intervention. An intensive physical therapy program was applied to this subject. The treatments included reciprocal crawling, high kneeling, tailor sitting, weight-bearing and shifting training to facilitate ankle balance strategies and training to walk without assistance. RESULTS: After the eight-week follow-up, the child achieved a gradual improvement in the gross motor function measures, and the mother reported that the child frequently engaged in tailor sitting and independently walking. CONCLUSION: This case study highlights that intensive physical therapy improved the overall motor function of a child with MECP2 duplication syndrome.

• Journal of Acupuncture Research
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• v.31 no.4
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• pp.81-97
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• 2014

Objectives : The purpose of this study is analyzing the current research methodology of pharmacopucture for the treatment of animal cancer models. Methods : Four electronic databases were searched for animal studies published from January 2000 to September 2014 onward using these search terms "cancer, anticancer, pharmacopuncture, beevenom". Selected articles were described about animal cancer models. The methods used to induce cancer and the outcome measures used to assess the effects of pharmacopuncture on animal cancer models were analyzed. Results : 37 articles were included. For producing animal cancer models BALB/C mice(n=22) and C57BL/6 mice(n=17) were selected. And intravenous injection of B16-F10 melanoma cells into tail vein(n=14) or intraperitoneal injection of sarcoma-180 cells(n=14) were frequently used to induce cancer. Various pharmacopunctures were injected into acupoints $CV_{12}(n=19)$, $ST_{36}(n=8)$, $BL_{18}(n=8)$ or peritoneal cavity(n=6), tumor site(n=2), tail vein(n=2). Outcome measures were categorized into anti-cancer, anti-metastasis, general condition, cytotoxicity, immune response, toxicity. Median Survival Time(MST) and increase of life span(ILS)(n=26) was frequently used for evaluating anti-cancer effects. And pulmonary colonization assay(n=13) was frequently used for evaluating anti-metastasis effects Conclusions : Based on these data, further research would be needed to ascertain the effectiveness of pharmacopuncture for treating cancer and broaden the range of clinical applications.

• The Journal of Korean Academy of Sensory Integration
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• v.13 no.2
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• pp.53-61
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• 2015

Objective : The purpose of this study was to investigate the effects on sensory integration interventions for korean children which focused on vestibular - proprioceptive system. Methods : Authors systematically searched published studies in DBpia, KISS and RISS databases from August to September 2015. Key words in the search were 'sensory integration intervention', 'sensory integration therapy' and 'vestibular-proprioceptive'. By using the inclusion and exclusion criteria, we selected seven studies for further analyses examining level of evidence and methodological qualities. Information for the analyses were on study designs, participants, interventions, outcome measures and results. Results : Grade IV rated evidence was found from five studies, and Grade III and Grade V rated evidence was found from one for each study. The methodological levels of the quantitative studies were 'fair' (2) and 'poor' (5). Subjects for the studies were developmental delay (5), Asperger Syndrome (1), and not specific diagnosis (2). Single-subject design was most frequently used and motor area were most frequently evaluated. The interventions used the studies showed positive effects on outcome measures. Conclusion : This study presented the summary of sensory integration intervention based on vestibular-proprioceptive system for Korean children. More studies with high level of evidence and various study designs need to be followed.

• Journal of Preventive Medicine and Public Health
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• v.27 no.2 s.46
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• pp.366-376
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• 1994

Patients' evaluation of hospital care is one of the most important aspects of quality assessment. Survey allows patients to judge sujectively the events that occur during their hospital visit if performed properly. This study describes the result of a research effort to develop outpatient questionnaire that has sufficient validity and reliability to be used to measure patients' perception of satisfaction in Korea and to investigate influencing factors on patients' satisfaction. Self-administered questionnaire was developed for outpatient and the survey was conducted covering 827 outpatients in a tertiary hospital. It was confirmed by factor analysis that patients evaluate several components of ambulatory care distinctly ; hospital environment, administration and ancillary services, and medical care. We found strong evidence of construct validity and internal consistency for the above three dimensions of hospital process. On the contrary, reliability of overall outcome measures was low. It suggests that three items concerning overall outcome measures have some different meanings in patients' perception. Using logistic regression analysis it was found that previous health status, cost evaluation, and improvement in health status have significant influences on the level of patients' overall satisfaction and that patient's sex, experience of previous visit, expectation for improvement, cost evaluation, and improvement in health status are strongly related with intention to recommend hospital. In spite of some limitations the results of this study can be used helpfully as baseline informations for developing self-administered questionnaire and for exploring the influencing factors on patients' satisfaction. Further comprehensive research efforts should be made on the measurement of ambulatory patients' satisfaction and its related factors in current Korean situation.

• Clinics in Orthopedic Surgery
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• v.10 no.4
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• pp.407-412
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• 2018

Background: We conducted this study to determine the optimal length of patellar and tibial bone blocks for the modified transtibial (TT) technique in anterior cruciate ligament (ACL) reconstruction using the bone-patellar tendon-bone (BPTB) graft. Methods: The current single-center, retrospective study was conducted in a total of 64 patients with an ACL tear who underwent surgery at our medical institution between March 2015 and February 2016. After harvesting the BPTB graft, we measured its length and that of the patellar tendon, patellar bone block, and tibial bone block using the arthroscopic ruler and double-checked measurements using a length gauge. Outcome measures included the length of tibial and femoral tunnels, inter-tunnel distance, length of the BPTB graft, patellar tendon, patellar bone block, and tibial bone block and graft-tunnel length mismatch. The total length of tunnels was defined as the sum of the length of the tibial tunnel, inter-tunnel distance and length of the femoral tunnel. Furthermore, the optimal length of the bone block was calculated as (the total length of tunnels - the length of the patellar tendon) / 2. We analyzed correlations of outcome measures with the height and body mass index of the patients. Results: There were 44 males (68.7%) and 20 females (31.3%) with a mean age of 31.8 years (range, 17 to 65 years). ACL reconstruction was performed on the left knee in 34 patients (53%) and on the right knee in 30 patients (47%). The optimal length of bone block was 21.7 mm (range, 19.5 to 23.5 mm). When the length of femoral tunnel was assumed as 25 mm and 30 mm, the optimal length of bone block was calculated as 19.6 mm (range, 17 to 21.5 mm) and 22.1 mm (range, 19.5 to 24 mm), respectively. On linear regression analysis, patients' height had a significant correlation with the length of tibial tunnel (p = 0.003), inter-tunnel distance (p = 0.014), and length of patellar tendon (p < 0.001). Conclusions: Our results indicate that it would be mandatory to determine the optimal length of tibial tunnel in the modified TT technique for ACL reconstruction using the BPTB graft. Further large-scale, multi-center studies are warranted to establish our results.

• Journal of Digital Convergence
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• v.11 no.2
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• pp.221-228
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• 2013

A number of research studies focus on the efficacy of using such as scenario based learning. However, desirable methods have not been introduced to assess the scenario based learning. This article is to suggest a fuzzy logic based framework for scenario base learning in which more reasonable learning effects are measured. It can be solved uncertain problems of linguistic variables. Also, we suggest three measures of accuracy, comprehensibility and completeness in order to evaluate accurate effects of scenario based learning. This assessment provides the scenario to the learner in which the scenario is presented in an authentic context, and enable the learner to reach an outcome through an adequate sequence and choices. This approach enables the system to present new scenarios and outcomes based on what a user selects. In particular, the application of fuzzy logic in scenario based learning can be easily pursued certain successful path or wrong path all the way through to reach major outcome in real situation.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.261-267
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• 2012

Purpose: The relationship between thymidylate synthase (TS) expression and outcomes in gastric cancer (GC) patients remains controversial, although most studies reported poor survival and reduced response to fluoropyrimidine were related to high TS in tumors. We carried out a systematic review of the literature with meta-analysis to estimate the predictive value of TS expression from published studies. Methods: We indentified 24 studies analysing the outcome data in gastric cancer stratified by TS expression. Effect measures of outcome were hazard ratios (HRs) for overall survival (OS) and event-free survival (EFS), or the odds ratio (OR) for overall response rate (ORR). HRs and ORs from these eligible studies were pooled using random-effects meta-analysis. Results: Fifteen studies investigated outcomes in a total of 844 patients with advanced GC, and nine studies investigated outcomes in a total of 1,235 patients with localized GC undergoing adjuvant therapy. Meta-analysis of estimates showed high TS expression was significantly associated with poor OS in the advanced setting (HR: 1.43, 95%CI: 1.08 - 1.90), and poor EFS in the adjuvant setting (HR: 1.53, 95%CI: 1.01 - 2.32). Subgroup analysis demonstrated TS expression to haves even greater value in predicting OS, EFS and ORR in advanced GC patients treated with fluoropyrimidine monotherapy (HR for OS: 2.32, 95%CI: 1.53 - 3.50; HR for EFS: 1.76, 95%CI: 1.19 - 2.60; OR for ORR: 0.32, 95%CI: 0.11 - 0.95). Conclusion: High levels of TS expression were asssociated with a poorer OS for advanced GC patients compared with low levels. In the adjuvant setting, high TS expression was also associated with a worse EFS. Additional studies with consistent methodology are needed to define the precise predictive value of TS.

• The Journal of the Korea Contents Association
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• v.10 no.7
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• pp.253-258
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• 2010

The image intensifier tube that is clinically used gets changed depending on its terms of use. As the brightness gets deteriorated and the performance gets decrease, the X-ray output needs to be increased to maintain the identical diagnosis outcome. As a consequence, the patients are exposed to the increased radiation. Since not many accurate studies have been made, this study measured the conversion factor and resolution depending on the use of the devices that were currently used in Korea. When comparison was made with a device with less than 1 year-use, the conversion factor of a device with 6 year-use got decreased up to 25% while its resolution was reduced from 3.4 lp/mm to 2.5 lp/mm. Such outcome highlights the necessary measures to be supplemented as the increased terms of use implied also the increased radiation exposure among the patients as well as difficulty to conduct an accurate exam.

• IE interfaces
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• v.17 no.3
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• pp.338-348
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• 2004

OECD countries including Korea positively adopt performance-based budget systems which convert an input-centered system to an output-centered system to solve two baffling problems: public expense retrenchment and efficiency recovery of government management. Output management of IT project propelled in public sector becomes a prominent figure influenced by these keynote of policy. However, it is placed in difficult circumstances to develop a performance index and the methodology to cover characteristics of IT project, measuring the goal achievement of business and the customer contentment according to the phases of business progress. Existing studies of IT project accomplishment measurement have been fulfilled on the subject of business targeting on IT technology application, administrative information network business and national base of information network construction. Most of the studies have been executed using BSC or AHP to reflect synthetically business specifics of IT project from a methodological point of view. In this study, we propose a structural equation model (SEM) to develop a performance index which measures the outcome of IT project according to the phases of business progress, avoiding a simple presentation of project outcome or conceptual frame. The proposed SEM is applied to the survey results of "IT support project for Small and medium business". Based on the fitted model, we apply ACSI concept to develop an Information Technologization Success Index (ITSI). This index allows us comparison of several IT vendors as well as feedback information for further improvement.

• Journal of Chest Surgery
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• v.38 no.1 s.246
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• pp.1-12
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• 2005

The primary responsibility of a perfusionist is to operate the heart-lung bypass machine during open heart surgery, which is vital for the successful operative outcome. However, despite the perfusionist's crucial role on the cardiac surgical team, no relevant studies have not yet been conducted in our country. In this regard, this study was performed about the current status of perfusionists in Korea with comparative analysis on the certification and education system of perfusionists in foreign countries. Material and Method: We analyzed the demographic data on the Korean perfusionists conducted in 1994 and 2003, with comparison of recent data on the perfusionists of the nineteen foreign countries. Result and Conclusion: Although all agree that professionalism and responsibility of the perfusionist are essential in conducting a cardiac procedure and bringing about successful outcome, the formally approved training and certification system for perfusionists have not yet been established in Korea. Adequate measures should be done as soon as possible in order to try to obtain the adequate recognition of the profession.