• The Journal of Internal Korean Medicine
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• v.11 no.1
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• pp.93-107
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• 1990

Studies on diagnosis and treatment of tumor . abscess . ulcer in intestinal carbuncle were carried out. The result of studies were summerized as follows: 1. By Nai-Gyung carbuncle-tumor arose from disharmony between nutrient and defensive because of cold, abscess arose from fever victory between cold and fever, ulcer arose from decreasing function of Bi-Kam year. By latter literature Bi-Kam year could be interpreted that spleen stomach was invaded evil influence from unattainable vital force of the earth. 2. Sites of intestinal carbuncle were large intestine, small intestine, intestinal inside or outside between large and small intestine, Intestinal carbuncle was common name of a disease about large intestinal carbuncle, small intestinal carbuncle, pelvic intestinal carbuncle, shrink leg intestinal carbuncle etc.. Pain appeared Chunchu-Hyul in large intestinal carbuncle, and Gwanweon-Hyul in small intestinal carbuncle. 3. On abdominal diagnosis tumor had indistinct pain of Gwanweon Chunchu, edema and heary feeling in low abdomen, no excessive pain by hand press and intestinal boiling sound. In abscess pain descended from right side of low abdomen to huckle, and there was rejection against press, feeling about fever,water sound with flank movement. In ulcer hand approach was difficult since excessive pain diffuse to whole abdomen, and perforating ulcer sometimes caused a serious symptom of umbilical pus. 4. On fecal and urinary diagnosis in tumor urine was yellowish red pollakiuria like gonorrhoea and occasional constipation. In abscess uncomfortable rough pain short red early urine like gonorrhoea appeared during urination, and constipation with stinging pain appeared during defecation. In ulcer red rough pyuria appeared, and stinging and pain with puruloid blood appeared during defecation. 5. On treatment in tumor Daiwhang-Tang Daisenggi-Tang Dangui-Jun by dissipation method, calming down method, interior reliance maturation method, in abscess Mokdan-San Euiiin-Tang Jeokduiin-Tang by the method of water repelling pus discharge, acute breaking, in ulcer Takridanggui-Tang Paljin-Tang Bojungikki-Tang were each used by the method of interior reliance, virulence astriction, supplement vital force and blood, supplement spleen stomach. 6. On treatment patient may have to be careful of excessive moving and suprising anxiety. Abuse of acupuncture and moxibustion made patient worse, misuse of analgesics purgative intestinal irrigation etc. could provoke difficult diagnosis and perforation. So you must treat after exact diagnosis. 7. Prognosis of ease tumor ease abscess ease ulcer and ease astriction was good. If the intestinal carbuncle were not to promote to abscess and ulcer for a long time, its prognosis was bad and it could metastasize to cancer because of dark purple with hardness. So tumor abscess ulcer in intestinal carbuncle may be significant of precancerous lesion.

• Clinical and Experimental Pediatrics
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• v.49 no.10
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• pp.1067-1072
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• 2006

Purpose : The purpose of this study was to examine the clinical courses and long-term outcomes of children with Allagille syndrome in Korea, and to evaluate the prognostic potentials of identified variables. Methods : We reviewed the clinical manifestations and outcomes of 30 children with Alagille syndrome, investigated from 1984 to 2006 until the end of this study (defined as death or last visit; mean follow-up : 5 years). Results : Cholestasis occurred in 100 percent, cardiovascular abnormalities in 83.3 percent, butterfly vertebrae in 30.0 percent, posterior embryotoxon in 43.3 percent, and a characteristic facial appearance in 100 percent. At study conclusion, of these 30 patients, eight had died (26.7 percent); six related to Alagille syndrome. Five patients died of a liver disease complication. Liver transplantation was carried out in five of the 30 patients (16.7 percent) and one of these died due to hyperacute rejection. At age two, cholestasis improved in 17 of the 30 patients. Those who had severe cholestasis at 2 years of age tended to have a complication, such as liver cirrhosis or liver transplantation, or to have died. Conclusion : Hepatic complications account for the most mortalities in patients with Alagille syndrome. Careful and complete assessments should be made in children who have cholestasis at 2 years of age. Further investigations of more cases are required.

• Development and Reproduction
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• v.21 no.2
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• pp.157-165
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• 2017

One of the reasons to causing blood coagulation in the tissue of xenografted organs was known to incompatibility of the blood coagulation and anti-coagulation regulatory system between TG pigs and primates. Thus, overexpression of human CD73 (hCD73) in the pig endothelial cells is considered as a method to reduce coagulopathy after pig-to-non-human-primate xenotransplantation. This study was performed to produce and breed transgenic pigs expressing hCD73 for the studies immune rejection responses and could provide a successful application of xenotransplantation. The transgenic cells were constructed an hCD73 expression vector under control porcine Icam2 promoter (pIcam2-hCD73) and established donor cell lines expressing hCD73. The numbers of transferred reconstructed embryos were $127{\pm}18.9$. The pregnancy and delivery rate of surrogates were 8/18 (44%) and 3/18 (16%). The total number of delivered cloned pigs were 10 (2 alive, 7 mummy, and 1 died after birth). Among them, three live hCD73-pigs were successfully delivered by Caesarean section, but one was dead after birth. The two hCD73 TG cloned pigs had normal reproductive ability. They mated with wild type (WT) MGH (Massachusetts General Hospital) female sows and produced totally 16 piglets. Among them, 5 piglets were identified as hCD73 TG pigs. In conclusion, we successfully generated the hCD73 transgenic cloned pigs and produced their litters by natural mating. It can be possible to use a mate for the production of multiple transgenic pigs such as ${\alpha}-1,3-galactosyltransferase$ knock-out /hCD46 for xenotransplantation.

• Korean Journal of Family Social Work
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• no.62
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• pp.71-102
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• 2018

The purpose of this study is to enrich our understanding of the family utilizing childcare by grandmothers and the elderly women by examining the experience of grandmothers who refused to support raising their grandchildren. The researcher focused on grandmothers who have been in charge of caring the family in the main and tried to explore the reasons for their decision not to take care of their grandchildren. For the purpose, Research participants were seven elderly women who have refused raising of their grand-children. Data were collected by in-depth interview and analyzed based on the phenomenological method. As results, it turned out that the elderly women refused caring of their grandchildren due to the burden of parenting and the rejection of an extended mother role, and the fear of family conflicts, but they felt sorry about their refusal of a request for caring support from their adult children. Second. these decisions caused various dynamics of the family members, and they were experiencing psychological difficulties. Third, elderly women perceived raising of grandchildren as a task of adult children or a problem for which the society should be accountable, and felt that the family and the society have shifted the responsibility to them. This research result confirms that a new generation of the elderly women have emerged who have different viewpoints on caregiving. It also presents a necessity to reflect the viewpoints of elderly who are mainly concerned when establishing a policy of caregiving. Based on this finding, this study also presents implications regarding support for family utilizing childcare by grandmothers and support for the elderly women.

• The Journal of the Korea Contents Association
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• v.21 no.6
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• pp.445-455
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• 2021

Interest in the origin of the universe and man has historically been one of the central themes of human inquiry. The question of origin is not just a matter of intellectual curiosity, but a matter of human identity and an important matter of human destiny. The traditional model presented in relation to the origin of man is largely the Christian creationism that all things originated from the Creator, the evolutionary theory that everything happened by chance and evolved from lower to higher animals, and the agnosticism that we cannot know anything about the origin. This study deals with the theory of theistic evolution, a combination of creationism and evolutionism. It is argued that the theory of the evolutionary origin was not an immediate creation, although all things originated from God, but through creation through a long evolutionary process. The theory of theistic evolution was proposed by combining two conflicting theories of origin in a Christian way, which has several essential problems, but this study pointed out two. First, the God of the Bible is reduced to the image of being confined to the laws of nature, not the Almighty Creator. Second, by interpreting the events of the Bible symbolically, it results in rejection of historicity. Therefore, it is more rational to choose either evolutionism or creationism rather than the theory of theistic evolution.

• Applied Biological Chemistry
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• v.46 no.2
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• pp.130-133
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• 2003

A method for separating heme-iron from hemoglobin (Hgb) hydrolysate by dialysis was developed. Recovery of heme-iron increased with increasing Hgb concentration, whereas rejection of peptide and separation effciency expressed by HP ratio (heme-iron/peptide) did not show significant differences. HP ratio increased with increases in the degree of hydrolysis of Hgb and $KH_2PO_4$ concentrations of dialysis solution. Recovery of heme-iron decreased with increase in the pH of dialysis solution due to wash-out of heme-iron across the dialysis membrane caused by increase in solubility of heme-iron. Rejections of peptide were 74.5 and 87.5% (2 and 5 kDa of cut off size, respectively), whereas recovery of heme-iron decreased from 86.5 (2 kDa) to 63.1% (25 kDa). Amounts of heme-iron and peptide of dried heme-iron product were 21.7 and 77.0%, and HP ratio and production yield were 28.2 and 6.5%, respectively.

• Journal of Korean Society of Environmental Engineers
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• v.39 no.9
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• pp.542-547
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• 2017

This paper was to analyze the membrane characterization of hydrophilicity, surface morphology and membrane chemical anlysis of three commercial microfiltration/ultrafiltration membranes, and evaluate the filtration performance of a seawater to assess the availability for pretreatment of desalination process. From the results of contact angle, Mem-3, fabricated with polyacrylonitrile, was highly hydrophilic. It find out that Mem-3 has more anti-biofouling property. In Field emission scanning electron microscope (FESEM), Mem-1 (polyethylene) and Mem-2 (Polyvinylidenefluoride) showed the sponge-like shape and Mem-3 showed finger-like shape. Membrane chemical analysis by energy dispersive spectrometer (EDS) presented that Mem-2 was mostly fluoride and Mem-3 had s high ratio of N (32.47%) due to the nitrile group. The permeation flowrate per time on suction pressures using deionized water (D.I. water) tends that permeation rate of Mem-3 more increased when the pressure was increased compared to other membranes. From the results of turbidity and total suspended solids (TSS) removal, turbidity of permeate was 0.191 NTU to 0.406 NTU and TSS was 2.2 mg/L to 3.0 mg/L in all membranes, indicating that it was not suitable for the pretreatment of seawater desalination by short-term experiments.

• Journal of Food Hygiene and Safety
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• v.17 no.3
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• pp.157-165
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• 2002

A two-year survey of consumers'awareness and perception of genetically-modified (GM) foods was conducted during May through September of 2000 and 2001 with a random sample of Korean consumers. More than 68% of the respondents were exposed to some information related to GM foods. The greatest benefit of the development of GM foods was thought to be the remedy for the food shortage in the future. More than 90% of Korean consumers wanted GM foods to be labeled. About 18% of the respondents would buy GM foods voluntarily, whereas over 49% would not until they found out more. Only 40% of Korean consumers were found to realize that food items originated ken plants contain genes. More consumers responded that they would not buy herbicide-tolerant GM soybean but buy vitamin-enriched GM soybean. It seemed to be that many Korean consumers do not make decisions of acceptance or rejection of GM foods not on the basis of biotechnology but on the basis of the word(5) used to describe the products, such as herbicide and vitamin. Only 4% of Korean consumers responded that GM foods were the greatest safety-threatening factor of Korean foods.

• International Commerce and Information Review
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• v.19 no.3
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• pp.153-174
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• 2017

The cultural values of the traditional way and the current cultural values of young people are very different, and the rejection of cross-cultural contact is greatly reduced because Korean young people easily accommodate other cultures of the US, Europe or Asia. At present, the cultural values of the traditional way and the current cultural values of young people are very different, and the youthfulness of Korean young people easily accepts other cultures of the US, Europe or Asia, so the resistance to cross - cultural contact is greatly reduced. The purpose of this study is to find out how the younger Korean youths are forming the change of the foreign culture and how the negotiation will proceed according to the formation of these cultures. The results of the analysis show that Korean young people have collectivism cultural rights and that they are consistent with the previous research that there is tendency to avoid uncertainty. On the other hand, there is a tendency of opposition as a result of the empirical analysis that the Koreans have a strong orientation, a high power interval, and strong masculinity. Also, as a result of analyzing the changes in Korean culture that belongs to the high background culture, Korean young people tend to be centered in the past and decision makers tend to decide by the chief executive. On the other hand, Korean young people were denied all the verifiable cultural attributes that cultural properties and communication that maintain openness to share space exposures and office space are non - verbal, tacit communication and time observation are very long and uncertain.

• Membrane Journal
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• v.26 no.4
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• pp.239-252
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• 2016

Two-dimensional materials offer unique characteristics for membrane applications to water technology. With its atomic thickness, availability and stackability, graphene in particular is attracting attention in the research and industrial communities. Here, we present a brief overview of the recent research activities in this rising topic with bringing two membrane architecture into focus. Pristine graphene in single- and polycrystallinity poses a unique diffusion barrier property for most of chemical species at broad ambient conditions. If well designed and controlled, physical and chemical perforation can turn this barrier layer to a thinnest feasible membrane that permits ultimate permeation at given pore sizes. For subcontinuum pores, both molecular dynamics simulations and experiments predict potential salt rejection to envisage a seawater desalination application. Another novel membrane architecture is a stack of individual layers of 2D materials. When graphene-based platelets are chemically modified and stacked, the interplanar spacing forms a narrow transport pathway capable of separation of solvated ions from pure water. Bearing unbeknownst permeance and selectivity, both membrane architecture - ultrathin porous graphene and stacked platelets - offer a promising prospect for new extraordinary membranes for water technology applications.