• Title/Summary/Keyword: original medicine

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Development of Diagnostic Indicator for the Sasang Constitution Exterior-Interior Disease Based on Original Symptom (사상의학의 표리변증에 대한 소증 진단지표 개발연구: 소음인, 소양인, 태음인을 중심으로)

  • Park, Minyoung;Lee, Min-jung;Hwang, Minwoo
    • Journal of Sasang Constitutional Medicine
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    • v.32 no.4
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    • pp.65-85
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    • 2020
  • Objectives The aim of study was to suggest diagnostic indicator according to Exterior-Interior disease for the Sasang Constitution based on original symptom. Methods We investigated the literature(『Dongeuisusebowon sinchukbon』) and another study(Clinical Practice Guideline for Disease of Sasang Constitutional Medicine: Diagnosis and Algorithm). As a result, we developed diagnostic indicator of original symptom for Exterior-Interior disease in Sasang Constitutional Medicine. Results and Conclusions Diagnosis of Exterior-Interior disease in Sasang Constitution was decided by heat and cold of original symptom. Detailed indicators of diagnosis in Exterior-Interior disease were heat/cold sensitivity, the degree of sweating, the amount of drinking water, thirst, face color and somatalgia.

A comparative analysis for the original references of prescriptions including Rhei Rhizoma in Dongeuibogam (동의보감(東醫寶鑑) 중 대황(大黃) 처방의 원저(原著) 비교 분석 연구)

  • Kim, An-Na;Lee, Chia-Wei;Oh, Yong-Taek;Jang, Hyun-Chul;Kim, Hong-Jin
    • Journal of Haehwa Medicine
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    • v.23 no.1
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    • pp.21-55
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    • 2014
  • Objectives : This report describes the original references of 154 formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam. Methods : This study analyzes the original references of 154 formulas including Rhei Rhizoma as a key component in Dongeuibogam. Results : There were five types as follows: 1.There is no exact match between 154 formulas in Dongeuibogam and the original formulas in references. 2. Case that could not found the original formula in reference: 22%. 3. Case that the citation is the similar to the original reference: 4%. 4. Case that the citation is not same to expression but contents basically: 73%. 5. Case of addition of content: 1% Conclusions : Most formulas related to the use of Rhei Rhizoma main blended from Dongeuibogam are similar to the contents in the original references. But we can find that Heo Jun, who writes Dongeuibogam, modifies the contents for his intention of editing, idea and situation in Korea.

Original Antigenic Sin Response to RNA Viruses and Antiviral Immunity

  • Mee Sook Park;Jin Il Kim;Sehee Park;Ilseob Lee;Man-Seong Park
    • IMMUNE NETWORK
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    • v.16 no.5
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    • pp.261-270
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    • 2016
  • The human immune system has evolved to fight against foreign pathogens. It plays a central role in the body's defense mechanism. However, the immune memory geared to fight off a previously recognized pathogen, tends to remember an original form of the pathogen when a variant form subsequently invades. This has been termed 'original antigenic sin'. This adverse immunological effect can alter vaccine effectiveness and sometimes cause enhanced pathogenicity or additional inflammatory responses, according to the type of pathogen and the circumstances of infection. Here we aim to give a simplified conceptual understanding of virus infection and original antigenic sin by comparing and contrasting the two examples of recurring infections such as influenza and dengue viruses in humans.

Study on the Development of Diagnosis and Assessment Instrument for the Original Symptom of Taeeumin (태음인 소증 진단평가도구 개발 연구)

  • Kwon, Jin-Hyeok;Lee, Jun-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.1
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    • pp.57-89
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    • 2021
  • Objectives This study is aimed to develop a standard instrument of diagnosis and assessment for the original symptom of Taeeumin. Methods 1. Based on the clinical practice guidelines, the works of Dong-mu, and the expert clinical judgment of the research team, the items to be used in the instrument of diagnosis and assessment for the original symptom of Taeeumin were extracted, and translation was proceeded in plain Korean for easy application and feasible use in daily clinical practice. As a result, candidate items for the diagnosis and assessment tool were derived. 2. An online questionnaire survey was conducted on the candidate items derived through the above process to the expert advisory group for (1) inclusion/exclusion as diagnosis and assessment index (2) evaluation of importance and (3) the validity of translation. Results & Conclusions Through survey of expert advisory group, the number of candidate items were reduced and the preliminary weights were assigned. And based on this, was developed. There were a total of 9 items for Exterior Cold[Wiwanhan] original symptom diagnosis and assessment tool, 21 items for Interior Heat[Ganyeol] original symptom, 15 items for Exterior Disease Unfavorable Patterns[Wiwanhan-paejo] original symptom, and 17 items for Interior Disease Unfavorable Patterns[Ganyeol-paejo] original symptom, and the weights were reflected in each response score so that the final total score could be calculated.

A Review on quotations in chapter of bone, Wehyungpyun, Dongeuibogam ("동의보감(東醫寶鑑)" "외형편(外形篇)" 골문(骨門) 인용문(引用文)에 대(對)한 고찰(考察))

  • Kwon, Hae-Kyung;Song, Ji-Chung;Jo, Eun-Hee
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.16 no.1
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    • pp.135-139
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    • 2010
  • Quotations in "Dongeuibogam" are originated from books of Oriental Medicine. Those are exactly same with original books. However, some quotations are not in same comparing to original books. Authors are in concerns that the original sentences which are quoted in "Dongeuibogam" are how different and how similar or same, with comparing methods between them. As a result, we could find out original sentences in original books and we could make comparison between those and quotations of chapter of bone in "Wehyungpyun", "Dongeuibogam". Also we could get explanations of qoutations' accuracies.

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Research on Oriental Medicine Diagnosis and Classification System by Using Neck Pain Questionnaire (경항통 설문지를 이용한 한의학적 진단 및 분류체계에 관한 연구)

  • Song, In;Lee, Geon-Mok;Hong, Kwon-Eui
    • Journal of Acupuncture Research
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    • v.28 no.3
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    • pp.85-100
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    • 2011
  • Objectives : The purpose of this thesis is to help the preparation of oriental medicine clinical guidelines for drawing up the standards of oriental medicine demonstration and diagnosis classification about the neck pain. Methods : Statistical analysis about Gyeonghangtong(頸項痛), Nakchim(落枕), Sagyeong(斜頸), Hanggang (項强) classified experts' opinions about neck pain patients by Delphi method is conducted by using oriental medicine diagnosis questionnaire. The result was classified by using linear discriminant analysis (LDA), diagonal linear discriminant analysis (DLDA), diagonal quadratic discriminant analysis (DQDA), K-nearest neighbor classification (KNN), classification and regression trees (CART), support vector machines (SVM). Results : The results are summarized as follows. 1. The result analyzed by using LDA has a hit rate of 84.47% in comparison with the original diagnosis. 2. High hit rate was shown when the test for three categories such as Gyeonghangtong and Hanggang category, Sagyeong caterogy and Nakchim caterogy was conducted. 3. The result analyzed by using DLDA has a hit rate of 58.25% in comparison with the original diagnosis. The result analyzed by using DQDA has a accuracy of 57.28% in comparison with the original diagnosis. 4. The result analyzed by using KNN has a hit rate of 69.90% in comparison with the original diagnosis. 5. The result analyzed by using CART has a hit rate of 69.60% in comparison with the original diagnosis. There was a hit rate of 70.87% When the test of selected 8 significant questions based on analysis of variance was performed. 6. The result analyzed by using SVM has a hit rate of 80.58% in comparison with the original diagnosis. Conclusions : Statistical analysis using oriental medicine diagnosis questionnaire on neck pain generally turned out to have a significant result.

Consideration of the Comparing the Original Texts with Quotations in Edema Chapter of Dong-Yi-Bo-Gam (동의보감 부종편의 원문과 인용문헌에 대한 비교고찰)

  • Yang Jun Suk;Ko Hyoung Gon;Jin Jae Ho;Han Woong;Jeong Sang Hun;Kim Ho;Lee Dong Ju;Lee Kwang Gyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.943-952
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    • 2004
  • We studied on the purpose of comparing the original texts with quotations in edema chapter of Dong- Yi-Bo-Gam. The research mainly depended on compare and consider these original text and quote. In Pyong Yeol Byong chapter of SoMoon, Su Yeol Hyul chapter of SoMoon, Pyong Yin Ki Sang chapter of SoMoon, Ja Jeol Jin Sae chapter of YoungChu, Emperor's Classic of Internal Medicine(黃帝內經;ECIM), We were able to find that some sentences about edema were quoted. Drug arrangement order that construct herb medicine is disposed depends on drug's weight, and all unit was concorded by Jeon and Pun. Quoted words in Emperor's Classic of Internal Medicine(黃帝內經;ECIM) does not perfectly match with original text. However, edema chapter of Dong- Yi-Bo-Gam is identical with original text, because only few words were deleted or inserted.

The Review on the Acne Related Articles Published in the Journal of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (한방안이비인후피부과학회지에 게재된 여드름과 관련된 논문에 관한 고찰)

  • Kim, Ji-Soo;Park, Soo-Yeon;Choi, Jeong-Hwa;Kim, Jong-Han;Rhee, Doo-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.27 no.3
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    • pp.26-39
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    • 2014
  • Objective : This study was carried out to analyze the trends of Acne related articles that have been published in the Journal of Korean Medicine Ophthalmology, Otolaryngology & Dermatology(JKOOD). Method : We studied 29 research papers relevant to Acne that published in JKOOD from 1998 to 2013. All the paper were classified into three categories; original article, review article and case report. We sub-classified the original articles into three categories; descriptive study, analytic study and experimental study. We analyzed the case report according to various types of treatment. Results : 1. The number of searched journals is 29 papers; 17 original ordicles, 4 review articles, 8 case reports. 2. Classification of 17 original articles into three categories; 10 experimental studies, 7 descriptive studies, 0 analytic study. 3. Method of Evaluation; Korean Acne Grading System(KAGS) is used frequently in descriptive studies and experimental studies. 4. Treatment in Case reports; 7 Case reports used External medical treatments. Conclusions : It is needed to develop the methods of grading system in acne related to Oriental medicine to obtain objectivity of studies. The number of analytic study, clinical trial and experimental study is need to increase.

A Review on Two Fructus Jujubae & Three Rhizoma Zingiberis Rencns in Prescription of "Dongeuibogam" ("동의보감(東醫寶鑑)"처방(處方) 중(中) 강삼조이(薑三棗二)에 관한 고찰(考察))

  • Keum, Kyung-Soo;Song, Ji-Chung;Eom, Dong-Myung
    • Journal of Korean Medical classics
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    • v.23 no.4
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    • pp.155-167
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    • 2010
  • Two Fructus Jujubae & three Rhizoma Zingiberis Rencns are usually used in parts of prescriptions in oriental medicine. In "Dongeuibogam", those are prescribed as drugs. However, those are not exactly same with original books, which "Dongeuibogam" had quoted. In original books, those are sometimes mentioned just as 'Fructus Jujubae & Rhizoma Zingiberis' or different amount of them. Therefore, authors try to compare with "Dongeuibogam" and its original books to find out the reason of discordance. As a result, we could conclude that Two jujubes & three pieces of ginger are more commonly prescribed than original books and are fixed to use more conveniently and to give standard for doctor.

A Clinical Case Report of Soyangin Patient with Peripheral Coldness (양독백호탕으로 호전된 소양인 사지 말단부위 냉증 환자 1례 보고)

  • Oh, Hyun-Joo;Hwang, Min-Woo
    • Journal of Sasang Constitutional Medicine
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    • v.29 no.3
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    • pp.288-297
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    • 2017
  • Objectives The purpose of this study was to report significant improvement of peripheral coldness in patient, who was diagnosed with 'Soyangin Chest-heat symptomatic pattern' and applied medication based on Sasang Constitutonal medicine. Methods The patient was treated with herbal medications, according to his own symptomatology. The objective outcome was measured by thermography and the subjective sensation was assessed by using Visual Analogue Scale (VAS). Results The symptoms of peripheral coldness improved remarkedly without any side effects. Accessory symptoms and original symptoms also changed for the better. Conclusions This results show that it is available that peripheral coldness is treated with herbal medications according to Sasang Constitutional medicine, especially ingenious in terms of the fact that some patient can be diagnosed with heat-based condition on the basis of original symptoms, although his/her chief complaint is classified as cold pattern.