• Restorative Dentistry and Endodontics
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• v.44 no.2
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• pp.20.1-20.8
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• 2019

Objectives: To achieve pulp-dentin complex regeneration with tissue engineering, treatment efficacies and safeties should be evaluated using in vivo orthotopic transplantation in a sufficient number of animals. Mice have been a species of choice in which to study stem cell biology in mammals. However, most pulp-dentin complex regeneration studies have used large animals because the mouse tooth is too small. The purpose of this study was to demonstrate the utility of the mouse tooth as a transplantation model for pulp-dentin complex regeneration research. Materials and Methods: Experiments were performed using 7-week-old male Institute of Cancer Research (ICR) mice; a total of 35 mice had their pulp exposed, and 5 mice each were sacrificed at 1, 2, 4, 7, 9, 12 and 14 days after pulp exposure. After decalcification in 5% ethylenediaminetetraacetic acid, the samples were embedded and cut with a microtome and then stained with hematoxylin and eosin. Slides were observed under a high-magnification light microscope. Results: Until 1 week postoperatively, the tissue below the pulp chamber orifice appeared normal. The remaining coronal portion of the pulp tissue was inflammatory and necrotic. After 1 week postoperatively, inflammation and necrosis were apparent in the root canals inferior to the orifices. The specimens obtained after experimental day 14 showed necrosis of all tissue in the root canals. Conclusions: This study could provide opportunities for researchers performing in vivo orthotopic transplantation experiments with mice.

• Journal of Korean Society of Water and Wastewater
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• v.33 no.2
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• pp.121-129
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• 2019

If sewage flows for an extended time at low velocities, solids may be deposited in the sewer. Sufficient velocity or tractive force should be developed regularly to flush out any solids that may have been deposited during low flow periods. This study aims to evaluate the periods (T) during which sewage flow greater than the minimum tractive force maintains on a spot in sewer pipe system with lower tractive force or lower velocity than expected in the design step, when a storage tank installed in a place upsteam pours water into the sewer. The effect to T of design factors of storage tank and sewer pipes was evaluated assuming the uniform flow in sewers. When the area of orifice in the storage tank is $0.062m^2$(or 0.28 m diameter), the maximum T of 31sec was maintained using the usually used preset range of values of several design factors. As the horizontal cross section of storage tank and water depth of storage tank and roughness in sewers increase, T linearly increases. Also, T linearly decreases as the diameter of a sewer pipe increases. Although T gradually decreases as the sewer pipe slope decreases to around 0.005, T decreases sharply when the slope is less than 0.003.

• Fire Science and Engineering
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• v.33 no.1
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• pp.99-104
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• 2019

In a gas system fire extinguishing system, extinguishing agents are usually stored with approximately 280 bar at $21^{\circ}C$ and are released at approximately 8 MPa through the decompression valve and orifice to quickly suppress the fire. When extinguishing agents are discharged, they cause a loud noise (approximately 140 dB), which can damage electronics, such as hard disk drives (HDDs). Therefore, the noise is becoming a serious issue in the gas extinguishing system. The method of the noise reduction by adding an absorbent is most general and in this study, the thickness of the absorbent was as a selected design variable. The noise level at the observation point and the flow characteristics inside the nozzle were numerically calculated and analyzed using the commercial code ANSYS CFX ver. 18.1.

• The Korea Journal of Herbology
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• v.36 no.1
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• pp.87-95
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• 2021

Objective : Liquidambaris Storax, the processed resin of Liquidambar orientalis Mill., has been therapeutically used as orifice-opening medicinals in Korean Medicine. However, unauthenticated resinous drugs from various origins were sold as Liquidambaris Storax. This study aimed to establish the quality assessment of genuine Liquidambaris Storax and to provide quantitative differences of Liquidambaris Storax in herbal markets. Methods : Bibliographic research on ancient Liquidambaris Storax was performed using classic books of herbology. The quality assessment was approached by searching modern books of herbal medicines. The marker compounds in Liquidambaris Storax from various origins were quantitatively analyzed using high-performance liquid chromatography. Results : L. orientalis was botanically characterized by palmately 5-lobed shape of leaves. Genuine Liquidambaris Storax was recognized as resinous or semi-solid form (ancient―Song dynasty) to liquid form (Myeong/Cheong dynasty) and two processed forms were available in current markets. Genuine liquid Liquidambaris Storax should be lengthened as a thread when it was lifted by a stick and be sunken under the water. The crystals of cinnamic acid was seen under microscopic observation and the scent of benzaldehyde occurred after the treatment with potassium permanganate. Cinnamyl alcohol, cinnamic acid, and cinnamaldehyde were quantified in two liquid samples of Liquidambaris Storax, while cinnamaldehyde was not quantified in resinous (semi-solid) sample. Conclusion : This study presents the detailed methods of quality assessment for genuine Liquidambaris Storax as well as the status in the herbal markets. Further quantitative study with diverse samples is required to establish the quality standard of Liquidambaris Storax.

• Applied Chemistry for Engineering
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• v.32 no.1
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• pp.102-109
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• 2021

Recently, an interest in risk calculation methods has been increasing in Korea due to the establishment of classification code for explosive hazardous area on gas facility (KGS CODE GC101), which is based on the international standard of classification of areas - explosive gas atmospheres (IEC 60079-10-1). However, experiments to check for leaks of combustible or toxic gases are very difficult. These experiments can lead to fire, explosion, and toxic poisoning. Therefore, even if someone tries to provide a laboratory for this experiment, it is difficult to install a gas leakage equipment. In this study we find out differences among actual experiments, CFD by using FLACS and calculation based on classification code for explosive hazardous area on gas facility (KGS CODE GC101) by comparing to each other. We develpoed KGS HAC (hazardous area classification) program which based on KGS GC101 for convenience and popularization. As a result, actual gas leak, CFD and KGS HAC are showing slightly different results. The results of dispersion of 1.8 to 2.7 m were shown in the actual experiment, and the CFD and KGS HAC showed a linear increase of about 0.4 to 1 m depending on the increase in a flow rate. In the actual experiment, the application of 3/8" tubes and orifice to take into account the momentum drop resulted in an increase in the hazardous distance of about 1.95 m. Comparing three methods was able to identify similarities between real and CFD, and also similarities and limitations of CFD and KGS HAC. We hope these results will provide a good basis for future experiments and risk calculations.

• Journal of the Korean Society of Propulsion Engineers
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• v.24 no.6
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• pp.1-9
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• 2020

Using kerosene and liquid oxygen, 1.5-tonf class liquid-liquid pintle injector with rectangular two-row orifice was designed and manufactured. The combustion test of the pintle injector was carried out to verify the combustion performance and combustion stability under a supercritical condition which is the actual operation condition of the liquid rocket engine. The combustion test result showed that the pintle tip was damaged by the high temperature combustion gas in the high-mixed ratio recirculation zone of the combustion chamber. To solve this problem, the insert nozzle was installed in the pintle injector to increase cooling performance at the pintle tip. As a result of the hot firing test, installation of the insert nozzle, AR and BF had a great effect on pintle tip cooling performance.

• Journal of the Korean Society of Propulsion Engineers
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• v.25 no.4
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• pp.59-70
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• 2021

An experimental study was conducted to observe the spray characteristics for different flow rates and rotating speeds of a rotating fuel nozzle of a slinger combustor. The water spray ejected from the nozzle orifice was visualized using a high-speed camera and a light source. It was confirmed that the atomization was improved, as the flow rate decreased and rotating speed increased. The characteristic maps for the spray characteristics and performance parameters showed that the aerodynamic Weber number and the liquid-air momentum flux ratio were associated with the liquid primary breakup, and the liquid-air momentum flux ratio and Rossby number were closely correlated with the liquid ejection mode.

• Tribology and Lubricants
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• v.38 no.2
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• pp.33-40
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• 2022

In this study, we present rotor dynamic analysis and operation test of a turbo expander for a hydrogen liquefaction plant. The turbo expander consists of a turbine and compressor wheel connected to a shaft supported by two hydrostatic radial and thrust bearings. In rotor dynamic analysis, the shaft is modeled as a rigid body, and the equations of motion for the shaft are solved using the unsteady Reynolds equation. Additionally, the operating test of the turbo expander has been performed in the test rig. Pressurized helium is supplied to the bearings at 8.5 bar. Furthermore, we monitor the shaft vibration and flow rate of the helium supplied to the bearings. The rotor dynamic analysis result shows that there are two critical speeds related with the rigid body mode under 40,000 rpm. At the first critical speed of 36,000 rpm, the vibration at the compressor side is maximum, whereas that of the turbine is maximum at the second critical speed of 40,000 rpm. The predicted maximum shaft vibration is 3 ㎛, whereas sub-synchronous vibration is not presented. The operation test results show that there are two critical speeds under the rated speed, and the measured vibration value agrees well with predicted value. The measured flow rate of the helium supplied to the bearing is 2.0 g/s, which also agrees well with the predicted data.

• Geomechanics and Engineering
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• v.28 no.5
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• pp.521-529
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• 2022

This research work deals with the development of air pluviation method for preparing uniform sand specimens for conducting large scale laboratory testing. Simulating real field conditions and to get reliable results, air pluviation method is highly desirable. This paper presents a special technique called air pluviation or sand raining technique for achieving uniform relative density. The apparatus is accompanied by a hopper, shutters with different orifice sizes and numbers and set of sieves. Before using this apparatus, calibration curves are drawn for relative density against different height of fall (H) and shutter sizes. From these calibration curves, corresponding to the desired relative density of 60%, the shutter size of 13mm and height of fall of 457.2 mm, are selected and maintained throughout the pluviation process. The density obtained from the mobile pluviator is then verified using the Dynamic Cone Penetrometer (DCP) test where the soil is poured in the box using defined shutter size and fall height. The results obtained from the DCP test are averaged as 60±0.5 which was desirable. The mobile pluviator used in this research is also capable of obtaining relative densities up to 90%. The instrument is validated using experimental and numerical approach. In numerical study, Plaxis 3D software is used in which the soil mass is defined by 10-Node tetrahedral elements and 6-Node plate is used to simulate plate behavior in the validation phase. The results obtained from numerical approach were compared with that of experimental one which showed very close correlation.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.3
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• pp.66-94
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• 2022

Objectives : Diabetic Foot Ulcer(DFU) is one of the common complications of diabetes. DFU is difficult to treat compared to other chronic wounds and clinically effective treatments are limited. The purpose of this study is to review the of external ointment treatment for DFU. Methods : 8 databases such as PubMed, EMBASE, CENTRAL, CNKI, NDSL, RISS, KISS, OASIS including English, Korean and Chinese were searched by structured search strategies that consist of terms as 'diabetic foot', 'diabetic foot ulcer(DFU)' and 'randomized' from January 2001 to January 2021. All randomized controlled trials(RCTs) involving treatment group as external ointment or in combination with conventional treatment were included. Results: A total of 20 RCTs was identified and analyzed. In treatment group, ointment was applied based on conventional treatment. A total of 16 different ointments were used, and the frequency of use was highest in the order of Heat-clearing drug, Blood-activating and stasis-dispelling drug, Tonifying and Replenishing drug and Orifice-opening drug. The most used herbs were in the order of Coptis chinensis Franch., Phellodendron chinense Schneid., Borneolum syntheticum., Angelica sinensis(Oliv.) Diels. In treatment group, a clinically effective effect was obtained compared to the contrast group. Conclusions : The result of this study suggest that external ointment treatment based on conventional treatment can be applied to DFU.