• 한방비만학회지
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• 제1권1호
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• pp.47-56
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• 2001

Objectives: We want to understand body composition and states of obese patients and the clinical studies of obesity attribute to Dept. of Oriental Rehabilitation Medicine. Methods : The clinical studies were done on 42 cases of obese patients who were treated by obesity clinic in Dept. of Oriental Rehabilitation Medicine Dae-Jeon Oriental medical hospital in Dae-Jeon University from May 2000 to September 2000. We checked body composition using Inbody3.0. Results : Sexual ratio on this report is 1:4.98(male: female). Abnormal eating is Major cause of obesity that has caused orthopedic disease. Increasing of BMI, fluid, protein and mineral mass decrease.

• 동의생리병리학회지
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• 제21권1호
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• pp.322-327
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• 2007

The purpose of this study was to investigate the change of female's Bone Mineral Density after taking herbal medicine. We examined age, sex, marriage, alcohol, smoking, and job of 76 female and their life style related with Osteoporosis. Bone Mineral Density was examined after 1 month (one herbal medicine), 2 months (two herbal medicine), and 3 months (three herbal medicine) between Group I (taking pear extract) and Group II (taking herbal medicine). Bone Mineral Density of Group II after 1 month was increased, but insignificant. Bone Mineral Density was not significantly different between the Group I and Group II after 2 and 3 months. In this study, we can conclude that Bone Mineral Density was increased after 1 month of taking herbal medicine. But we had inaccurate results due to limitations of this study: period of test, accuracy of instrument, impossibility of use young antlers of the deer, and etc. More detailed study should be conducted to yield more concrete results.

• 동의생리병리학회지
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• 제18권4호
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• pp.1159-1162
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• 2004

We studied on the production of the ceramic by the mineral-Oriental medicine and the property of the clean active water depositting on the ceramic stone. The results are as follows: We properly mixed of maifanshi, mica, ochre, and added to a small amount cinnabar, and therefore formed the ceramic stone. By the plasticity process and the irradiating magnetic force recovered the disappeared a part of constitutent elements. The recovered effects were become higher the freshness, maintenance, deodoriztion, clean water. As well as having the ability on capture of the notoxious heavy metal on human. The ceramic powder were mixed proper dose maifanshi, mica. And the powder had ionization, absorption, adhesion by the plasticity process and magnetic force. The clean active water of depositting on the ceramic stone during 24hours were observed significant the content of micro element, dissolved oxygen, abstraction on Herbs.

• 한방비만학회지
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• 제4권1호
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• pp.67-80
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• 2004

Objectives: Obesity is a growing epidemic with subsequent health consequences leading not only to reduced quality of life but also to increased medical costs. Recently nutritional balances are emphasized in the field of obesity, and especially maintaining proper equilibriums of minerals. The correlation of minerals obtained from the method of HTMA(Hair Tissue Mineral Analysis) with obese degree has not been studied in Korea yet. We studied any significant difference of mineral concentrations and components according to the obese degree. Methods: 78 subjects were analyzed who visited Garosero clinic of oriental medicine to lose their weight from June to November 2004. We used BMI(Body Mass Index), PBF(Percent Body Fat), WHR(Waist-Hip Ratio) and abdominal circumference obtained by bio-electrical impedance analysis as an obese degree. And we analyzed correlation with mineral concentrations and ratios obtained from HTMA. Results & Conclusion: 1. Na, K, Zn, Se had significant correlation with obese degree in case of nutritional minerals from HTMA. Especially, K had high significance. 2. Toxic minerals from HTMA had no significance with obese degree. 3. Rb had significant correlation with obese degree in case of additional minerals from HTMA. 4. Among important ratios from HTMA, Na/K had significant correlation with obese degree, but Ca/K had correlation except PBF, and Na/Mg had correlation except WHR. 5. Among toxic ratios from HTMA, Se/Hg had significant correlation with obese degree, but S/Hg had correlation except BMI. 6. Na, K, Zn, Rb, Na/K, Ca/K had significant differences between obesity groups classfied by BMI. Ob II group had sinificant difference from NW group in cases of K, Zn, Rb, Na/K, and Ob II group had sinificant difference from OW group in case of Ca/K.

• 동국한의학연구소논문집
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• 제9권
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• pp.1-23
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• 2000

Osteoporosis is a common disorder characterized by reduced bone mineral density, deterioration of the microarchitecture of bone tissue and increased risk of fracture. The aim of treatment of osteoporosis is to maintain and, ideally, to restore bone strength safely. In recent years the role of polypeptide growth factors in bone metabolism has begun to appear. It has been proposed that alterations in the expression or production of growth factor can modulate the proliferation and activity of bone forming cells. Thus, the role of structurally diverse peptides for the management and diagnosis of osteoporosis has attracted the attention of many investigators. This paper reviews numerous findings concerning the use of polypeptides, hormones, and growth factors, for the management of osteoporosis. Many of the compounds mentioned here are experimental prototypes of new therapeutic classes. Though it is unlikely that some of the compounds may ever be used clinically, development of safe and efficacious agents in each class will define the future course of therapy for osteoporosis.

• 혜화의학회지
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• 제10권2호
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• pp.73-81
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• 2002

In the literal study of anti-tumor effects of Jakeumjung. the results were as follows. 1. Jakeumjung is a traditional oriental medical prescription which is composed of Cremastare appeniculatae tuber, Euphorbiae pekinensis radix, Toosendan fructus, Chinensis galla, Moschus, Realgar and Cinnabaris. 2. Jakeumjung is applied to patients by administering or external application. When it is administered for patients, pertinent dose is 0.6~1.5g twice or three times per one day. When it is applied by external application, we melt it by water or vinegar and apply it to patients. 3. Effects of Jakeumjung are expelling toxin and pestilence, counteracting pathogen and relieving stagnation, detumescence and stopping pain. So it is used for detoxification from ancient. In recent, it is often used for cancer such as breast cancer, pancreatic cancer, epigastric cancer, acute leukemia, lymphoma, thymus cancer and skin cancer. 4. From the various experiments, Jakeumjung has been proved to have antifungal and antitumor effects. It inhibits and kills L7212, L1210 cells of leukemia. Especially, it acts in S stage of cell period. 5. Jakeumjung includes mineral medicines such as Realgar, Cinnabaris. So if we execute progressive study for anticancer effects and safety, the boundary of oriental medicine of using mineral medicines for cancer therapy will magnify in the future.

• 대한예방한의학회지
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• 제5권1호
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• pp.31-40
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• 2001

Legal permissible limit of herbal drugs metal level in Korea is define 'less 30.0ppm in total(except mineral drugs)' including Pb Hg Cd As Cr Ni etc. This limit has a lot of problems in several factors, that is, not divide hazard and essential elements, not consider high and low toxic effect in each metal, not calculate dose-response relationship and average health behavior in Korean etc. As a that result, It has strong limits and weakness in the basic toxicology and Oriental medicine. To improve and correct these factors, We need to several new approach as like below. It must be radical study following problems in short and middle-long period in the future, toxic metal and essential element must be divide to basic toxicology and also be diverse toxic effect. But mineral drugs that included a amount of severe toxic metals is being used as active prescription drug until now. If toxic, safety and side-effect of metals will be considered, mineral drugs must prohibit instantly or use at least after examined toxic effect. But one of the most important things about herbal drugs contamination, all people and department (government, farmer and trader, oriental medicine doctors and association) will be participate cooperative and collection for preventive or the least contamination in herbal drugs.

• 동의생리병리학회지
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• 제18권6호
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• pp.1548-1551
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• 2004

studied on the physicochemistrical property of the clean active water depositting on the ceramic stone by the mineral-Oriental medicine. The results are as follows. The cluster of the clean active water is observed 53-66.5㎐ for contral water. The clean active water is observed 7.2 ph and 1.3330 refractive index for contral water. In the chemical experimental test by ICP, the clean active water is observed 102℃ in boiling point and 4.8㎎/100g V.E for 0㎎g/100g of contral water. In the antibiotic experimentation, an anion, the dimintion index of bacilli, radiation degree and radiate energy of the clean active water increased for contral water. And in the deodorization experimentation, the clean active water is observed 95% deodorization index.

• 동의생리병리학회지
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• 제19권4호
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• pp.1011-1015
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• 2005

Antitumor and anti-metastatic effects of mineral powder(MP) were studied. In the present study, MP did not exhibit the any cytotoxic activity against leukemic cells such as L1210 and U937 tumor cell lines in vitro. Also, MP did not exhibit the any cytotoxic activity against solid cells such as A549 and B16-BL6 tumor cell lines in vitro. However, in vivo, MP exhibit a significant antitumor activity in BDF1 mice bearing Lewis lung carcinoma cells(LLC) with inhibition rates of 46 and $23\%$ at 200 and 100 mg/kg/day, respectively. Furthermore, in pulmonary colonization assay, MP exhibit the inhibitory effect of tumor metastasis. From these results, it was concluded that MP had antitumor and anti-metastatic activity suggesting its application for the prevention and treatment of cancer.

• 대한한방부인과학회지
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• 제19권3호
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• pp.203-213
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• 2006

Purpose : This study was carried out to evaluate correlation between Bone Mineral Density(BMD) and degenerative lumbar disease in postmenopausal low back pain patients. Methods : 69 postmenopausal patients with low back pain were examined. Magnetic resonance imaging was performed to evaluate degenerative lumbar disease and bone mineral density of lumbar spine was measured by Dual energy X-ray absorptiometry. Data were analyzed by Pearson's Linear Correlation Coefficient. Results : In postmenopausal patients with low back pain, BMD(T-score, Z-score) had negative correlation with the grade of intervertebral disc herniation and positive correlation with weight. Other lumbar diseases including Spinal stenosis, Spondylolisthesis and Facet joint arthrosis didn't have significant correlation with BMD. Conclusion : In postmenopausal patients with low back pain, BMD(T-score, Z-score) had inverse relationship with the grade of intervertebral disc herniation.