• Journal of Acupuncture Research
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• 제20권2호
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• pp.50-67
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• 2003

Objective : The purpose of this study was to evidence the effect of Dong-Shi Acupuncture by improving degree of forty four patients who have received a Dong-Shi Acupuncture therapy at Dong Eui oriental hospital OPD and chiefly complained for neck pain and related symptoms. Materials and Methods: Forty four patients were diagnosed with physical inspection and radiography, and investigated into the effect of treatment sharing before treatment and after 2 weeks and 4 weeks treatment by Dr. Kim's method. Results and Conclusions: The conclusion of this study was that improving degree of forty four patients who have received a Dong-Shi acupuncture therapy for all items and excellence of the Dong-Shi Acupuncture was evidenced.

• 혜화의학회지
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• 제20권1호
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• pp.39-50
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• 2011

In western, aromatherapy uses essential oils to prevent and treat disease, and is one of the ways to stay healthy. In oriental medicine, there was also a similar medical treatment using aromatic herbs for a long ago. The exisiting research of oriental medical herbs is mainly focused on the theory of qi and flavor(氣味論). But on aromatherapy used with aromatic herbs, it is necessary to study the aromatic herbs by aroma. So "xi$\bar{a}$ng p$\check{u}$, 香譜" and "b$\check{e}$n c$\check{a}$o g$\bar{a}$ng m$\grave{u}$, 本草綱目" mainly contain the study about clinical effects of aromatic herbs. And "b$\check{e}$n c$\check{a}$o p$\check{i}$n hu$\grave{i}$ j$\bar{i}$ng y$\grave{a}$o, 本草品彙精要"mainly explains the effects of medical herbs with five aroma classification of x$\bar{i}$ng(腥), sh$\bar{a}$n(膻), xi$\bar{a}$ng(香), ch$\grave{o}$u(臭), xi$\check{u}$(朽). The former one makes more clinical uses of medical herbs, and the latter one grows up the theory of medical herbs. This study is expected to have a good influence on aromatherapy and classification of oriental medical herbs.

• 동의생리병리학회지
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• 제16권6호
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• pp.1277-1283
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• 2002

Silsosangami(SSG) is a formula of treaditional korean medicines as an effective biological response modifier for augmenting host homeostasis of body circulation. Little is known of the biological activity of SSG and previous studies have focused mainly on their anti-thrombosis8). There is a growing interest in the pharmacological potential of the SSG due to the recent finding by our group that SSG and each constituent herbs of SSG were able to inhibit NO and prostaglandin E2 (PGE2) synthesis in murine peritoneal macrophages stimulated with bacterial endotoxin. In this paper, the effects of SSG on platelet aggregation and hemolysis in human blood were studied. SSG provoked remarkable inhibiting effect on platelet aggregation, and APTT were sensitive to the presence of this SSG. Using an in vitro system, APTT was delayed with the increment of the concentrations of these seven compounds. These results suggested that SSG might be used as a novel antithrombotic therapeutic agents in post-myocardial infarction. A SSG reduced NO production in mouse peritoneal macrophages stimulated with lipopolysaccharide, without the influence on the activity of iNOS being observed. SSG significantly reduced mouse paw edema induced by carrageenan. Western blot analysis showed that SSG reduced the expression of iNOS. The results indicate that SSG exerts anti-inflammatory effects related to the inhibition of NO production, which could be due to a decreased expression of iNOS.

• 한방안이비인후피부과학회지
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• 제24권3호
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• pp.108-118
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• 2011

Objective : This study was designed to evaluate the influence of time from onset of Bell's palsy until commenced Oriental medicine therapy on Bell's palsy. Methods : We investigated 35 cases of patients with peripheral facial palsy who visited Wonkwang University Oriental Hospital from 10th, December 2010 to 31st August, 2011 and classified them as time from onset of Bell's palsy until commenced Oriental medicine therapy. Time from onset of Bell's palsy until commenced Oriental medicine therapy of Group A was within 3 days. Group B was from 4 days to 8 days. We evaluate the treatment effect of each group by House-Brackmann grade before treatment and 1,3 week treatment. Results : 1. There was a statistical difference in period from onset of Bell's palsy until commenced Oriental medicine therapy between Group A and Group B. 2. There was a statistical difference after 1 week treatment in Group B. 3. There was a statistical difference after 3 weeks treatment in both Group A and B.3. After 3 week treatment, there was statistical significant difference in decreased value of House-Brackmann grade between Group A and Group B. Group A showed more recovery compared with Group B. Conclusions : 1. These results suggest that early oriental medicine treatment could be more effective in recovery of Bell's palsy. 2. Further studies will be required to identify the beneficial effect of early oriental medicine treatment in bell's palsy.

• 대한한의진단학회지
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• 제11권1호
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• pp.157-166
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• 2007

Background: The change in the respiratory pattern has an influence on the change in the autonomic nervous system, which in turn has an influence on the EGG to measure a gastric activity. However, the study on the influence on the EGG parameters by respiratory control and on the correlation between the HRV and EGG through respiratory control has not been perform yet. Objective: It is to perform a series of experiments to find out how the EGG parameters are influenced by the controlled respiration and what correlation there may exist between the EGG and HRV to measure the change in the autonomic nervous system after controlled respiration. Methods: 1st Experiment: During a 15minutes' voluntary respiration, HRV was measured, and it was measured again during another 15 minutes' controlled respiration. 2nd Experiment: After an eight hours' fast, EGG was measured for a period of 30 minutes, and then after another 15 minutes' voluntary respiration, a test-meal was offered for 10 minutes and again EGG was measured. The next day, after an 8 hour's fast, EGG was measured for 30 minutes, and after a 15 minutes' controlled respiration and offered with a test-meal for 10 minutes and then EGG was measured again for 30 minutes. Results: 1. It was observed in all the channels that the power ratio increased more after controlled respiration than after voluntary respiration. No statistical significance, however, could be observed. 2. Through controlled respiration, the HF of HRV and the power ratio of EGG Channel 4 was negatively correlated, while the LF/HF of HRV and the power ratio of EGG channel 1 & 4 was positive correlated. Such correlations as mentioned above, however, could not be observed in HRV & EGG through voluntary respiration. Conclusions: 1. It was concluded that the increase in the power of gastric contractile after controlled respiration is bigger than the increase in the power of gastric contractile after voluntary respiration. 2. It was concluded that the gastric contractile power and sympathetic activity through controlled respiration was negatively correlated, while the gastric contractile power and parasympathetic activity through controlled respiration was positively correlated.

• 대한한의학회지
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• 제25권4호
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• pp.171-179
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• 2004

Objective : This study was undertaken for discovering the characteristics of sleep in ordinary symptoms based on the Sasang Constitution. The result of this study could be helpful to understand and to identify patients such as Taeumin, Soyangin Soeumin or Taeyangin. Methods : There were 1,229 patients (529 men), who answered the questionnaire about their ordinary sleeping patterns. They were diagnosed, including their clinical Sasang Constitution, by the Sasang Constitution specialist at Bundang Oriental Hospital of Dongguk University. By applying the multinomial and binary logistic regression analysis to those collected materials, we can measure the characteristics and the influence of ordinary sleeping patterns to the dependent variable (Sasang Constitution). Results : In order of the item's influence that had decided one's constitution, between Taeumin and Soeumin, Taeumin snored frequently or well more than Soeumin, Soeumin had more dreams and more sleeping times than Taeumin, and Taeumin struggled frequently or well more than Soeumin. Between Soyangin and Soeumin, Soeumin dreams more frequently than Soyangin, Soyangin snored frequently or well more than Soeumin, and Soeumin has more sleeping times than Taeumin. Between Taeumin and Soyangin, Taeumin snored frequently or well more than Soyangin. Between Taeyangin and a group of the other constitutions, Taeyangin felt unwell after sleeping more than the other constitutions, the other constitutions awaked frequently more than Taeyangin during sleeping. Conclusion : This study will be used for identifying patients as Taeumin, Soyangin, Soeumin or Taeyangin by contrast with each other.

• 혜화의학회지
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• 제20권1호
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• pp.11-23
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• 2011

Systemic Lupus Erythematosus(SLE) is an autoimmune disease invading the skin, joint, kidney, intestinal membrane, neurosystem and other organs. SLE is an autoimmune disease characterized by immune dysregulation resulting in the production of antinuclear antibodies(ANA), generation of circulating immune complexes, and activation of the complement system. In Korean medicine, lupus can be classified as acute arthritis, reddish butterfly erythema, asthenic disease, edema and so on. The cause and procedure of the diseases are flourishing noxious heat, excessive fire due to deficiency of yin, blood stasis due to stagnation of qi, internal movement of the liver-wind, congenital deficiency, exhausted vital-qi, which are treated by clearing away heat and cooling the blood, nourshing yin and extinguishing fire, treating flatulence and activating blood circulation, nourishing the blood to expel wind, invigorating the liver and kidney, invigorating qi and replenishing the blood. To experimentally examine the influence of Insam-Buja-Tang (Ginseng & Aconiti Extract, IBT) on the outbreak and development of lupus, lupus induce MRL/MpJ-Faslpr lupus-prone mice model was used. As IBT was orally administrated to a lupus model mouse, various tests such as the weight, urine protein, renal function, Lymph cell test of the spleen, Cytokine expression, histopathological analysis of kideny were performed to see the influence on the kidney and whether it work effectively on the immune function. The main purpose of this study is to evaluate the effect of IBT on MRL/MpJ-Faslpr lupus-prone mice model. The effect of IBT on MRL/MpJ-Faslpr lupus-prone mice that can have autoimmune disease similar to SLE in human was evaluated after IBT per oral in the present study.

• 대한추나의학회지
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• 제1권1호
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• pp.83-90
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• 2000

Oryeong-San, Pangpungtongseong-San, Rangkyeoksanwha-Tang, Sipeemikwanjoong -Tang and Taeumjoui-Tang are not only examined using the code which are related to overweight in the QRIS but are also investigated the level of Free Radical using the Free Radical Measurement after steeping those 5 prescriptions in water. The results are as follows: 1. We indicated in the study of QRIS that 5 kinds of medicines which used most frequently In the treatment of the obesity appeared to affect the Immune system, spleen, kidneys, pancreas, the fatigue toxicity, TSH, and the metabolic disability but did not influence high on the contents of overweight and those of fatty cell, as well. in addition, there were no significant differences between the prescriptions as regards testosterone and progesterone. 2. In the Free Radical Measurement, Rangkyeoksanwha-Tang evaluated significantly high level of Free Radical, whereas others appear to have the similar level of Free Radical. These findings suggest that the treatment of the obesity affects particular body parts with respect to the control of overweight, although those medicines are not related directly to the areas(such as fatty cell Code), it is possible that they influence on the cure for the obesity. Furthermore, they indicate that with soaking prescription, Free Radical is not produced as much as we expected.

• 대한한의학회지
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• 제17권2호
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• pp.117-132
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• 1996

The study of Jungpung(中風)'s section in Chungumyobang (千金要方, 諸風門) by Sonsamak(孫思邈) showed the following results. 1. The cause of Jungpung(中風) in Jungpung(中風)'s section in Chungumyobang (千金要方, 諸風門) was quotated from the theory of Naekyung(內經) -Pung(風) evil from the external environment invade on Hu(虛) of human body(外來風邪, 內虛邪中). 2. At Jungpung(中風)'s section in Chungumyobang (千金要方, 諸風門), he devided into the four classes of Jungpung(中風)'s symptom-Pyungo, Pungbi, Pungyi, Pungbi(偏枯, 風?, 風懿, 風痺)-, and this classification had a great influence on the next generations. 3. At Jungpung(中風)'s section in Chungumyobang (千金要方, 諸風門), he understanded that changes of Jungpung(中風)'s pathology depended on the Eum-Yang-Han-Yul-Hu-Shil(陰陽寒熱虛實) of the patients. 4. At Jungpung(中風)'s section in Chungumyobang (千金要方, 諸風門), he gathered and rearranged various prescription which accumulated the clinical experiences during the period from Naekyung(內經), Sanghan(傷寒) times, to Tang(唐)'s dynasty. There were major Jungpung(中風)'s prescription -Sosokmyungtang(小續命湯), Daesokmyungtang(大續命湯), Jukryuktang(竹瀝湯), Jihwangjun(地黃煎), Dokhwalgisaengtang(獨活寄生湯) etc. And the principle of treatment was the remedy method of removing evil through sweating(發汗祛邪法). 5. Chungumyobang(千金要方) showed the development of quality, quantity in their prescription comparing the fomer ages. And the method of classification of Jungpung(中風)'s symptom had a great influence on the next generation in clinical aspect. But the basic theory in Chungumyobang(千金要方) coudn't get out of the limits of Naekyung(內經), Gumgueyoryak(金?要略).

• 대한한의학회지
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• 제34권4호
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• pp.12-20
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• 2013

Objectives: This study compared Gumiganghwal-tang (GGT) decoctions produced using different pressure levels for various extraction times to determine the optimal extraction conditions through hydrogen ion concentration (pH), total soluble solids content (TSSC), extraction yield, and content of chemical compounds. Methods: Decoctions were prepared by the pressure levels of 0 or $1kgf/cm^2$ for 30-180 min. The pH and TSSC were measured, the extraction yield was calculated, and the amounts of the chemical compounds were determined using high performance liquid chromatography. Results: The higher pressure and longer extraction time decreased the pH value, while those conditions increased TSSC and extraction yield: the decoction produced in 180 min by pressurized method showed the minimum value of pH, but maximum values of TSSC and extraction yield. The chemical compounds showed higher amounts in decoctions produced by non-pressurized methods than pressurized methods and their amounts were decreased over the peak extraction time in both pressurized and non-pressurized methods. The results of regression analysis confirmed the correlative influences of the pressure and extraction time on pH, TSSC, and extraction yield. Conclusions: This study suggests that pressure and extraction time influence the compositional constituents in GGT decoctions, and the non-pressurized method for 120 min should be chosen as the optimal extraction condition for the preparation of GGT decoction.