• 환경위생공학
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• 제15권3호
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• pp.8-14
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• 2000

This paper was conducted to examine the level of total and organic mercury in the scalp hair by the consumption pattern of fish. The scalp hair samples were collected from the occipital part of 101 in coastal, 106 in rural. The total and organic mercury contents of adult scalp hair increased with age up to the forties and slightly decreased in the fifties. (p<0.01) The mercury contents of the persons who were favorite dishes of fish were most high, and who prefer fish were 2 times higher than those of the persons who prefer vegetables and broiled. The contents of total and organic mercury in scalp hair showed a increasing tendency with the intake frequency of raw and cooked fish. (p<0.01) The total and organic mercury contents in the raw fishes were over 2 times higher than those in the boiled fishes.

• Journal of Preventive Medicine and Public Health
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• 제45권6호
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• pp.335-343
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• 2012

Mercury is emitted to the atmosphere from various natural and anthropogenic sources, and degrades with difficulty in the environment. Mercury exists as various species, mainly elemental ($Hg^0$) and divalent ($Hg^{2+}$) mercury depending on its oxidation states in air and water. Mercury emitted to the atmosphere can be deposited into aqueous environments by wet and dry depositions, and some can be re-emitted into the atmosphere. The deposited mercury species, mainly $Hg^{2+}$, can react with various organic compounds in water and sediment by biotic reactions mediated by sulfur-reducing bacteria, and abiotic reactions mediated by sunlight photolysis, resulting in conversion into organic mercury such as methylmercury (MeHg). MeHg can be bioaccumulated through the food web in the ecosystem, finally exposing humans who consume fish. For a better understanding of how humans are exposed to mercury in the environment, this review paper summarizes the mechanisms of emission, fate and transport, speciation chemistry, bioaccumulation, levels of contamination in environmental media, and finally exposure assessment of humans.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.206-208
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• 2002

Methylmercury (MeHg; $CH_{3}HgCl$) is, second only to cadmium as being, the most toxic on the earth. Inorganic mercury from various waste sources can be easily methylated by bacteria in water and subsequently ingested by fishes and then highly accumulated in human. Although toxicity from mercury exposure occurs with both organic and inorganic forms, organic mercury is more potently toxic to central nervous system. Minamata disease is an example of organic mercury toxicity. (omitted)

• 대한화학회지
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• 제41권8호
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• pp.392-398
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• 1997

무기수은과 유기수은을 분리하여 각각을 정량하는 방법을 연구하였다. 고분자량 알킬의 4차아민의 염, Aliquat 336의 $CHCl_3$ 용액을 이용하여 수용액 중에 함유된 무기수은이온, $Hg^{2+}$을 티오시안 착이온으로서, 그리고 유기수은 화합물, $CH_3HgCl$ 및 $C_2H_3O_2$ $HgC_6H_5$ 등을 동시에 추출농축한 다음 무기수은은 3 M $HClO_4 $ 용액으로 선택적인 역추출을 하여 CVAAS로 정량하고, 유기수은은 추출액의 $CHCl_3$ 을 증발 제거한 후 그 찌끼를 4% $KMnO_4 $-1M $H_2$$S0_4 $ 용액으로 분해하여 무기수은 이온으로 만들어서 역시 CVAAS로 정량하였다. 시료용액 50 mL 중에 함유된 Hg로서 1 ${\mu}g$의 무기수은과 유기수은 혼합용액(0.02 ${\mu}gHg/mL$)을 분석한 결과 절대오차 ${\pm}6%$ 이내의 결과를 얻었다.

• Environmental Engineering Research
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• 제24권1호
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• pp.54-62
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• 2019

The effects of UV wavelength and dissolved organic carbon (DOC) on the formation of dissolved gaseous mercury (DGM) were investigated in a controlled environment. To remove any other influences than UV wavelength and DOC, purified water was used as the working solution. DGM was instantly produced with irradiation of all UV lights even without DOC; whereas, there was no noticeable increase of DGM during irradiation of visible light. The amount of formed DGM increased as the DOC concentration increased even in dark conditions; however, UV-B irradiation significantly promoted DGM production with DOC present. The rate constants of reduction ranged from $1.4{\times}10^{-6}s^{-1}$ to $3.5{\times}10^{-5}s^{-1}$, with the lower values occurring under the dark condition without DOC and the higher values resulting under UV-B irradiation and high DOC concentration. However, DGM production was not linearly correlated with the DOC concentration at higher range of DOC in this study. Future studies should investigate the effects of DOC concentration on mercury (Hg) reduction over the broad range of DOC concentrations with different DOC structures and with other influencing parameters.

• Journal of Preventive Medicine and Public Health
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• 제27권1호
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• pp.44-58
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• 1994

어패류 섭취양상에 따른 총수은 및 유기수은의 체내 축적정도를 조사하기 위하여 1991년 6월부터 8월 사이에 경북지방의 해안지역, 도시지역 및 산간지역에서 남자국민학생 115명과 남자 성인 131명, 총 246명의 두발중 총수은 및 유기수은 함량을 수은분석장치 (Model IL 440)를 갖춘 원자흡광분광광도계 (Model IL 551)로 선택적 환원기화법에 의해 분석하였다. 학생군의 경우 생선 및 조개류와 생선통조림 및 어묵류를 선호하는 군의 두발중 총수은(각각 7.728ppm, 6.969ppm) 및 유기수은 함량(각각 6.610ppm, 5.885ppm)이 육류(총수은; 4.822ppm, 유기수은; 3.905ppm)나 야채류(총수은; 3.974ppm, 유기수은; 3.224 ppm)를 선호하는 집단보다 현저히 높았다(각각 p<0.01). 생선통조림을 먹는 방법에 따른 두발중 총수은 및 유기수은 함량은 그대로 먹는 경우가 야채사라다와 섞어서 또는 찌개로 먹는 경우보다 높게 나타났다(p<0.01). 생선통조림, 생선 조리반찬 및 생선회 섭취빈도가 많을 수록 두발중 총수은과 유기수은 함량이 많아 거의 매일 먹는 군이 거의 먹지 않는 군에 비해 2배 이상 높게 나타났으며(p<0.01), 생선을 주로 먹는 방법에 따라서는 회로 먹는 경우가 탕이나 구워서 먹는 경우 보다 현저히 높았다(p<0.01). 성인군의 경우 연령에 따른 두발중 수은 함량은 총수은과 유기수은 함량 모두 40대까지는 연령증가에 따라 증가했으나, 50대 이후는 약간 감소하였다. 직업별로는 어업 및 횟집 종사자가 농부에 비해 2배 이상 높았다. 또한 선호반찬 종류에 따라서는 생선 및 조개류를 선호하는 군이 가장 높았으며, 생선을 먹는 방법에 따른 두발중 수은 함량은 회로 먹는 군이 탕이나 구워서 먹는 군보다 2배 이상 높은 수준을 나타내었다. 생선회, 생선조리반찬 섭취빈도에 따른 두발중 총수은 및 유기수은 함량은 섭취빈도가 증가함에 따라 높아지는 경향을 보였다(각각 p<0.01). 이상의 결과로 보아 두발중 수은 함량은 어패류와 생선통조림의 섭취 빈도가 높을 수록 증가하였으나 중독증상을 나타낼 수 있는 농도에는 크게 못 미쳤다.

• Applied Microscopy
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• 제28권4호
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• pp.551-561
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• 1998

The autometallographic method was used to demonstrate the localization of mercury deposits in spleen of mouse. The mercury deposits were identified with the light and electron mocroscope. Mice were treated with methylmercuric chloride in the drinking water (demineralized water) for 40 days. Control and mercury treated groups showed no significant differences in mean body weight and spleen weight per one mouse. Mercury grains were appeared in the germinal center of white pulp consist of a preponderancing lymphocytes, not in red pulp and capsule. At the ultrastructural level, mercury deposits were restricted to lysosomes of macrophage and lymphocyte. Specially, volume in lysosomes of the macrophage was increased. These results suggest that mercury localization in lysosomes is associated with the change of immune activity.

• 대한의생명과학회지
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• 제14권3호
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• pp.187-192
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• 2008

To clerify the protective effect of omega-3 of polyunsaturated fatty acid docosahexaenoic acid (DHA) on the cytotoxicity induced by organic mercury in cultured NIH3T3 fibroblasts. The measurement of cell viability on ogranic mercury wad done by XTT assay after NIH3T3 fibroblasts were cultured with various concentrations of methyl mercuric chloride (MMC). And also, the effect of DHA on the MMC-mediated cytotoxicity was examined by cell viability, and antioxidant effect of DHA was also assessed by superoxide dismutase (SOD)-like activity and the lipid peroxidation activity in cultured NIH3T3 fibroblasts. In this study, MMC decreased cell viability and $XTT_{50}$ value was determined at $50{\mu}M$ of MMC in these culture. In the effect of DHA against the cytotoxicity induced by MMC, DHA significantly increased the cell viability damaged by MMC in cultured NIH3T3 fibroblasts. And also, DHA showed the antioxidant effect by showing the increase of SOD-like activity and the decrease of lipid peroxidation activity. From these results, it is suggested that organic mercury such as MMC has highly toxic effect on cultured NIH3T3 fibroblasts, and also, omega-3 of polyunsaturated fatty acid, DHA showed the protection on MMC-induced cytotoxicity and antioxidant effect.

• Journal of Preventive Medicine and Public Health
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• 제45권6호
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• pp.344-352
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• 2012

Mercury is a toxic and non-essential metal in the human body. Mercury is ubiquitously distributed in the environment, present in natural products, and exists extensively in items encountered in daily life. There are three forms of mercury, i.e., elemental (or metallic) mercury, inorganic mercury compounds, and organic mercury compounds. This review examines the toxicity of elemental mercury and inorganic mercury compounds. Inorganic mercury compounds are water soluble with a bioavailability of 7% to 15% after ingestion; they are also irritants and cause gastrointestinal symptoms. Upon entering the body, inorganic mercury compounds are accumulated mainly in the kidneys and produce kidney damage. In contrast, human exposure to elemental mercury is mainly by inhalation, followed by rapid absorption and distribution in all major organs. Elemental mercury from ingestion is poorly absorbed with a bioavailability of less than 0.01%. The primary target organs of elemental mercury are the brain and kidney. Elemental mercury is lipid soluble and can cross the blood-brain barrier, while inorganic mercury compounds are not lipid soluble, rendering them unable to cross the blood-brain barrier. Elemental mercury may also enter the brain from the nasal cavity through the olfactory pathway. The blood mercury is a useful biomarker after short-term and high-level exposure, whereas the urine mercury is the ideal biomarker for long-term exposure to both elemental and inorganic mercury, and also as a good indicator of body burden. This review discusses the common sources of mercury exposure, skin lightening products containing mercury and mercury release from dental amalgam filling, two issues that happen in daily life, bear significant public health importance, and yet undergo extensive debate on their safety.

• Journal of Preventive Medicine and Public Health
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• 제17권1호
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• pp.217-221
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• 1984

In order to estimate interfering effects of mercury and lead on biochemical oxygen demand (BOD), BOD in 18 effluent samples were measured under three different concentrations of mercury and lead. The results obtained were as follows: 1. Biochemical oxygen demand(BOD) was decreased under the presence of mercury and lead, with parallel correlation of mercury concentration. 2. High correlations were noted between original BOD concentration and decreasing amount of BOD when concentrations of mercury or lead were increased. 3. When the lead concentration was high, the close correlation was observed between total organic carbon(TOC) and decreasing amount of BOD. 4. There was a negative correlation between TOC/BOD ratio and decreasing amount of BOD when the mercury concentrations were high.