Signaling and Proteomics in Methylmercury Exposure

Methylmercury (MeHg; $CH_{3}HgCl$) is, second only to cadmium as being, the most toxic on the earth. Inorganic mercury from various waste sources can be easily methylated by bacteria in water and subsequently ingested by fishes and then highly accumulated in human. Although toxicity from mercury exposure occurs with both organic and inorganic forms, organic mercury is more potently toxic to central nervous system. Minamata disease is an example of organic mercury toxicity. (omitted)