• 한국치위생학회지
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• 제11권4호
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• pp.511-522
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• 2011

Objectives : The purpose of this study was to provide some information on the development of oral health care programs geared toward diabetics and ways of promoting their oral health. Methods : The subjects in this study were 586 diabetics who were selected from the 2009 third-year raw data of the 4th(2007~2009) National Health & Nutrition Survey. The data were analyzed with the statistical package SPSS 12.0 to grasp the influence of their sociodemographic characteristics and oral health behaviors on the presence or absence of periodontal diseases and missing tooth. Results : 1. Periodontal diseases were twofold more prevalent among the men than the women(p<0.01). By age, those who were in their 60s had 1.11-fold more periodontal diseases than those who were in their 70s and up(p<0.05). 2. The men and women were similar to each other in the number of missing tooth. By age, the number of missing tooth got smaller in proportion to decrease in age. By income, the number of missing tooth was 1.48-fold larger among the patients who earned an income of one million won or less than those who earned an income of two million won or more(p<0.01). Conclusions : The above-mentioned findings suggest that prospective cohort studies should be implemented to present prediction models of periodontal diseases and diabetes instead of merely sticking to cross-sectional studies. And oral health programs should be developed based on the findings of cohort studies to encourage diabetics to care about their oral health, and in which way they should be helped to promote their oral health should carefully be considered.

• International Journal of Oral Biology
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• 제48권2호
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• pp.9-18
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• 2023

The rapid detection of bacteria in the oral cavity, its species identification, and bacterial count determination are important to diagnose oral diseases caused by pathogenic bacteria. The existing clinical microbial diagnosis methods are time-consuming as they involve observing patients' samples under a microscope or culturing and confirming bacteria using polymerase chain reaction (PCR) kits, making the process complex. Therefore, it is required to analyze the development status of substances and systems that can rapidly detect and analyze pathogenic microorganisms in the oral cavity. With research advancements, a close relationship between oral and systemic diseases has been identified, making it crucial to identify the changes in the oral cavity bacterial composition. Additionally, an early and accurate diagnosis is essential for better prognosis in periodontal disease. However, most periodontal disease-causing pathogens are anaerobic bacteria, which are difficult to identify using conventional bacterial culture methods. Further, the existing PCR method takes a long time to detect and involves complicated stages. Therefore, to address these challenges, the concept of point-of-care (PoC) has emerged, leading to the study and implementation of various chair-side test methods. This study aims to investigate the different PoC diagnostic methods introduced thus far for identifying pathogenic microorganisms in the oral cavity. These are classified into three categories: 1) microbiological tests, 2) microchemical tests, and 3) genetic tests. The microbiological tests are used to determine the presence or absence of representative causative bacteria of periodontal diseases, such as A. actinomycetemcomitans, P. gingivalis, P. intermedia, and T. denticola. However, the quantitative analysis remains impossible, and detecting pathogens other than the specific ones is challenging. The microchemical tests determine the activity of inflammation or disease by measuring the levels of biomarkers present in the oral cavity. Although this diagnostic method is based on increase in the specific biomarkers proportional to inflammation or disease progression in the oral cavity, its commercialization is limited due to low sensitivity and specificity. The genetic tests are based on the concept that differences in disease vulnerability and treatment response are caused by the patient's DNA predisposition. Specifically, the IL-1 gene is used in such tests. PoC diagnostic methods developed to date serve as supplementary diagnostic methods and tools for patient education, in addition to existing diagnostic methods, although they have limitations in diagnosing oral diseases alone. Research on various PoC test methods that can analyze and manage the oral cavity bacterial composition is expected to become more active, aligning with the shift from treatment-oriented to prevention-oriented approaches in healthcare.

• 치위생과학회지
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• 제22권1호
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• pp.1-8
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• 2022

Background: The elderly have, a higher disease morbidity than other age groups due to a decrease in resistance to the disease and have complex diseases, so care should be taken. Accordingly, it is considered important to provide information for improving the health of the elderly. Health information plays an important role in individual health promotion and education, so the degree of exposure to information about oral health of the elderly is expected to have a significant impact on understanding and acquiring information on oral content videos on the importance, prevention, and management of oral health of the elderly in the future. Methods: This study analyzed video content related to oral diseases of the elderly in a total of 150 videos uploaded on YouTube from January 1, 2012 to May 13, 2021, using a total of three books of dental hygiene for the elderly. Results: Forty-nine broadcasters accounted for the most of this information. Among the information providers, there were two dental hygienists. They accounted for 1.3% of all the information providers. The highest number of dental hygienists who broadcasted information was 42 in 2019. The average number of views was 37,303 periodontal diseases, the highest. Among the videos, dry mouth was the most common with 34 oral diseases. Conclusion: The number of images for each disease varies, so it seems that information should be provided in various ways. Dental hygienists should widely improve oral health knowledge by providing various dental hygiene management images for each oral disease to improve the oral health of the general public. In addition, based on the information of the Health Insurance Review and Assessment Service, the development and provision of content should be actively carried out so that people can obtain the information they desire.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권1호
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• pp.55-58
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• 2007

The fibromatoses are a broad group of fibrous proliferations. They have a biologic behavior and histopathologic pattern that is intermediate between those of benign fibrous lesions and fibrosarcoma. Because they are not common diseases, it is important to differentiate the fibromatoses from other similar diseases. In this report, we present a case of fibromatosis, and possible other diseases to be differentiated, with a review of literatures.

• 한국산학기술학회논문지
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• 제19권4호
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• pp.245-253
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• 2018

본 연구는 국민건강영양조사 제6기(2015년) 원시자료를 이용하여 20~65세의 경제적인 능력을 갖고 있는 2,088명의 근로자를 최종연구대상자로 선정하였다. 본 연구의 목적은 경제활동자의 만성질환과 구강건강행태의 연관성을 조사하고 구강질환의 위험인자를 알아보기 위해 시행하였다. 연구결과 다음과 같다. 치아우식증은 주관적인 구강건강상태, 치통경험, 교정치료경험, 씹기문제, 말하기문제, 구강검진 및 치과의료기관이용과 관련성이 나타냈다. 치주질환은 구강건강상태, 치통경험, 교정치료경험, 씹기 및 말하기문제와 관련성을 나타냈다. 만성질환과 구강건강행태가 구강질환에 미치는 위험도는 다음과 같다. 정상에 비해 고혈압은 1.37배, 비만은 1.48배, 당뇨군은 1.5배, 저HDL-콜레스테롤혈증, 1.31배, A형 간염항체는 1.53배 더 높은 것으로 나타났다. 건강상태는 좋은군에 비해 나쁜 상태가 치아우식증 1.70배, 치주질환 2.10배 높은 것으로 나타났다. 치통경험은 치아우식증 1.30배, 치주질환 1.35배 높은 것으로 나타났다. 씹기문제는 치아우식증 1.76배, 치주질환 1.78배, 스트레스는 치아우식증과 치주질환 모두 1.44배 높은 것으로 나타났다. 흡연자는 치아우식증 1.61배, 치주질환 1.63배 더 높은 것으로 나타났다. 이상의 결과로 볼 때 만성질환은 치주질환의 발생위험률을, 구강건강행태는 치아우식증과 치주질환의 발생위험률을 증가시키는 것으로 파악되었다. 치아우식증은 구강건강관리만 잘해준다면 만성질환으로 이활 될 위험도가 낮아지는 것으로 보이나, 치주질환은 만성질환과 구강건강관리 모두가 중요하다고 여겨진다.

• 한국치위생학회지
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• 제13권2호
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• pp.323-334
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• 2013

Objectives : The purpose of this study was to examine the oral health care and educational needs of college students in an effort to give some suggestions on the development of oral health educational media. It's basically meant to boost the efficiency of oral health education geared toward college students. Methods : The subjects in this study were 500 students at seven different colleges located in Daejeon and South Choongcheong Province. After a survey was conducted, frequency analysis and ANOVA were utilized to analyze the collected data. And the records of the in-depth interviews of 10 students were analyzed as well. Results : The gender of the students and whether their major was linked to health or not made differences to their knowledge of dental caries. And there was nothing to affect their knowledge of periodontal diseases except whether their major was related to health or not. They didn't have a good knowledge of periodontal diseases, and they just regarded toothbrushing as a means to prevent dental caries and periodontal diseases. They preferred to acquire knowledge over the Internet. Conclusions : College students who don't know well about periodontal diseases should be given an opportunity to learn about periodontal diseases and diverse ways of preventing dental caries and periodontal diseases other than toothbrushing. As the college students preferred to surf the Internet, educational programs should be developed in the form of video clips that can be found over the Internet, and more aggressive publicity is required via SNS, etc.

• Journal of Oral Medicine and Pain
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• 제47권2호
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• pp.107-108
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• 2022

Artificial intelligence (AI) refers to the use of machines to mimic intelligent human behavior. It involves interactions with humans in clinical settings, and augmented intelligence is considered as a cognitive extension of AI. The importance of AI in healthcare and medicine has been emphasized in recent studies. Machine learning models, such as genetic algorithms, artificial neural networks (ANNs), and fuzzy logic, can learn and examine data to execute various functions. Among them, ANN is the most popular model for diagnosis based on image data. AI is rapidly becoming an adjunct to healthcare professionals and is expected to be human-independent in the near future. The introduction of AI to the diagnosis and treatment of oral diseases worldwide remains in the preliminary stage. AI-based or assisted diagnosis and decision-making will increase the accuracy of the diagnosis and render treatment more precise and personalized. Therefore, dental professionals must actively initiate and lead the development of AI, even if they are unfamiliar with it.

• Molecules and Cells
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• 제39권3호
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• pp.186-194
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• 2016

Epidemiological evidence suggests that bone is especially sensitive to oxidative stress, causing bone loss in the elderly. Previous studies indicated that human amnion-derived mesenchymal stem cells (HAMSCs), obtained from human amniotic membranes, exerted osteoprotective effects in vivo. However, the potential of HAMSCs as seed cells against oxidative stress-mediated dysfunction is unknown. In this study, we systemically investigated their antioxidative and osteogenic effects in vitro. Here, we demonstrated that HAMSCs significantly promoted the proliferation and osteoblastic differentiation of $H_2O_2$-induced human bone marrow mesenchymal stem cells (HBMSCs), and down-regulated the reactive oxygen species (ROS) level. Further, our results suggest that activation of the ERK1/2 MAPK signal transduction pathway is essential for both HAMSCs-mediated osteogenic and protective effects against oxidative stress-induced dysfunction in HBMSCs. U0126, a highly selective inhibitor of extracellular ERK1/2 MAPK signaling, significantly suppressed the antioxidative and osteogenic effects in HAMSCs. In conclusion, by modulating HBMSCs, HAMSCs show a strong potential in treating oxidative stress- mediated bone deficiency.

• Journal of Periodontal and Implant Science
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• 제33권1호
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• pp.113-126
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• 2003

• 대한치위생과학회지
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• 제1권2호
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• pp.41-52
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• 2018

The purpose of this study was to examine the state of oral prophylaxis practice among dental hygiene students and their awareness of musculoskeletal diseases in an effort to provide some information on how to strengthen education on treatment posture to manage musculoskeletal diseases and how to raise awareness of musculoskeletal diseases. From November 2 to 13, 2016, a self-administered survey was conducted on 653 sophomores, juniors and seniors with an experience of oral prophylaxis practice. SPSS version 20.0 for Windows was employed to analyze the collected data. The findings of the study were as follows: 1. The largest group that accounted for 37.4% responded that the total number of students undergoing oral prophylaxis practice during a semester was four to six. The biggest group that represented 65.4% answered that the required practice time per student was one to fewer than three hours. 76.0% continued to be in the repeated same posture. 2. As for the posture of patients, supine position was most common for the maxillary sinus, which accounted for 82.2%. And semi-upright position was most common for the mandibular sinus, which represented 49.6%. 3. In regard to the burden of oral prophylaxis practice, 33.9% considered the required for the practice appropriate. 42.3% took the repeated long-lasting posture, and 53.5% were under physical pressure. 55.4% suffered from mental pressure and stress. 4. The most dominant musculoskeletal area that they experienced pain after oral prophylaxis practice was neck with 52.5%; waist with 48.2, shoulders/wrists/hands with 45.5, back with 10.3, buttocks with 4.1, elbows with 2.3, legs with 2.1, ankles/feet with 0.8 and knees with 0.6%. 5. Concerning the maintenance of repeated treatment postures and pain experience, the students who continued to be in the repeated same position underwent more pain than the others who didn't on the shoulders(2.92±1.05), in the waist(3.02±1.01), buttocks(1.75±0.92), elbows(1.55±0.79) and ankles/foot(2.52±1.25). The differences were statistically significant(p<.05, p<.01). 6. As to educational experience on treatment posture and musculoskeletal diseases, 88.8% received education on treatment posture; 87.9%, on what position should be taken in times of cooperation; 46.9%, on musculoskeletal diseases; 51.9%, on carpal tunnel syndrome; 42.3%, on varicose vein. The students who replied education on occupational diseases was necessary accounted for 89.6%. 7. The students who experienced treatment posture education were better aware of the causes of musculoskeletal diseases(3.23±3.00), ways for preventing the diseases(3.33±.834) and how to stretch the body(3.63±.858). The differences were statistically significant(p<.05, p<.001). 8. The students who experienced education on occupational diseases heard more about musculoskeletal diseases(3.27±.965), were better cognizant of the causes of the diseases(3.45±.847), were better aware of how to prevent them(3.55±.805) and found themselves to know how to stretch to prevent the diseases (3.73±.826). The differences were statistically significant(p<.001).