• 대한기계학회논문집A
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• 제33권8호
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• pp.745-752
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• 2009

In robust design, the mean and variance of design performance are frequently used to measure the design performance and its robustness under uncertainties. In this paper, we present the Gauss-type quadrature formula as a rigorous method for mean and variance estimation involving arbitrary input distributions and further extend its use to robust design optimization. One dimensional Gauss-type quadrature formula are constructed from the input probability distributions and utilized in the construction of multidimensional quadrature formula such as the tensor product quadrature (TPQ) formula and the univariate dimension reduction (UDR) method. To improve the efficiency of using it for robust design optimization, a semi-analytic design sensitivity analysis with respect to the statistical moments is proposed. The proposed approach is applied to a simple bench mark problems and robust topology optimization of structures considering various types of uncertainty.

• Archives of Pharmacal Research
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• 제11권3호
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• pp.185-196
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• 1988

The inflence of hydrophilic vehicles on percutaneous absorption rate of griseofulvin was studied using intact skin of full thickness of hairless rat. The in vitro absorption rates were used as the characteristics for deciding the optimum formula of ointment vehicles. The optimum formula of vehicle compositions for maximum absorption rate was obtained from the polynomial regression equation and the two graphical techniques, contour graph and partial derivative graph. It was composed of sodium lauryl sulfate (1.65 W /W%), white petrolatum (16.5 W /W%), propylene glycol (12.0 W /W%), and stearyl alcohol (19.6W /W%). The experimental value obtained from the optimum formula and the prediction value were 33.99 and 33.87 ${\mu}g/\sqrt{min}$, respectively. From these results, it was believed that optimum formula for semisolid dosage forms could be obtained from the application of the optimization technique used in this study.

• 전자공학회논문지
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• 제53권8호
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• pp.59-65
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• 2016

본 논문은 대량의 stream data를 처리하는 어플리케이션에서 하드웨어 가속기들이 접근하는 메모리가 non-cacheable에서 cacheable으로 변경됨에 따라 발생할 수 있는 데이터 일관성 문제를 고려하여 시스템 최적화를 진행하였다. 이를 위해 상위 수준 시뮬레이션을 통한 프로파일링 결과를 토대로 분석식을 만들어 활용하였다. 실험한 결과 여러 이미지 크기에서 메모리가 cacheable로 변경됨에 따라 평균 1.40배의 성능 향상을 보였다. 분석식의 주요 파라미터 최적화를 통해 최종적으로 3.88배의 성능 이득이 발생했으며, 항상 메모리가 cacheable인 경우의 성능이 항상 우월한 것은 아님을 확인할 수 있었다.

• 한국자동차공학회논문집
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• 제8권6호
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• pp.238-246
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• 2000

In this paper, an optimization method of thin walled beam structures is proposed, Stiffnesses of a thin walled beam are characterized by the thickness of thin plates and the shape of the typical section of the beam. Explicit formula for section properties such as area, area moment of inertia, and torsional constants are derived using the response surface method. The explicit formula can be used for the optimal design of a structural system which consists of complicated thin walled beams. A vehicle structural system is optimized to demonstrate the proposed method.

• Archives of Pharmacal Research
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• 제16권1호
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• pp.43-49
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• 1993

The polyvinyl alcohol (PVA) hydrogel containing 1-methy-2-pymolidinone (MP) and sorbitol was preapred by the freeze and thaw method. The release rate of indomethacin from PVA hydrogel was used as a criterion for deciding the optimum formula of hydrogel using the computer optimization technique. The hydrogel of optimum formula was composed of PVA (10 w/v%), MP (0 w/v%) and sorbitol (40 w/v%) and the release rate of indomethacin was 1.981$\mu$g/ml$\cdot{min}^{1/2}$.

• Journal of Pharmaceutical Investigation
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• 제21권1호
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• pp.23-32
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• 1991

Dissolution profiles of ketoconazole in solid dispersion system (SDS) were investigated in the second fluid (pH 6.8) for the dissolution test (KPV). PVP K-30 and methyl cellulose were used as carriers in SDS, and chloroform as a solvent. Computer optimization technique was applied to obtain an optimum formula of SDS, and the following results were obtained; 1) Dissolution rate of ketoconazole in SDS was larger than that of pure ketoconazole in the second fluid of pH 6.8. 2) PVP K-30 and methyl cellulosr were good carriers for SDS of ketoconazole. Moerover PVP K-30 was better than methyl cellulose. 3) The optimum formula of ketoconazole SDS obtained from computer optimization technique was chloroform 175 ml, PVP K-30 5g and methyl cellulose 0.2g per 1g of ketoconazole. 4) The experimental value of $A_{60}$ (Amount released from ketoconazole tablet during 60 minutes) obtained from SDS by optimum formula agreed well with the value calculated by polynomial regression equation.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2002년도 봄 학술발표회 논문집
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• pp.123-130
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• 2002

A general formulation for shape design sensitivity analysis over three dimensional beam structure is developed based on a variational formulation of the beam in linear elasticity. Sensitivity formula is derived based on variational equations in cartesian coordinates using the material derivative concept and adjoint variable method for the displacement and Von-Mises stress functionals. Shape variation is considered for the beam shape in general 3-dimensional direction as well as for the orientation angle of the beam cross section. In the sensitivity expression, the end points evaluation at each beam segment is added to the integral formula, which are summed over the entire structure. The sensitivity formula can be evaluated with generality and ease even by employing piecewise linear design velocity field despite the bending model is fourth order differential equation. For the numerical implementation, commercial software ANSYS is used as analysis tool for the primal and adjoint analysis. Once the design variable set is defined using ANSYS language, shape and orientation variation vector at each node is generated by making finite difference to the shape with respect to each design parameter, and is used for the computation of sensitivity formula. Several numerical examples are taken to show the advantage of the method, in which the accuracy of the sensitivity is evaluated. The results are found excellent even by employing a simple linear function for the design velocity evaluation. Shape optimization is carried out for the geometric design of an archgrid and tilted bridge, which is to minimize maximum stress over the structure while maintaining constant weight. In conclusion, the proposed formulation is a useful and easy tool in finding optimum shape in a variety of the spatial frame structures.

• 한국군사과학기술학회지
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• 제21권5호
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• pp.572-582
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• 2018

In this paper, we have calculated a formular for sabot-trajectory of shipboard projectile including ship motion and generated trajectory-range function for analysing interference with structure of naval ship. We make formula to approximate the ship motion data of naval ship using optimization technique. Through this formula, we calculate the velocities and accelerations of sabot caused by ship motion(surge, sway, heave, roll, pitch, yaw) and then, we produce the formula about the trajectory of sabot including effects of ship motion in addition to previous study which had considered the effects of the pressure of flume, friction force, etc. To investigate interference with ship structures, we make the trajectory-range functions and then extract the nearest or farthest trajectory to ship structure. Through these data, we can conform whether the interference is happened or not.

• International Journal of Fluid Machinery and Systems
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• 제8권4호
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• pp.311-317
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• 2015

It is difficulty to calculate velocity circulation in centrifugal pump impeller outlet accurately. Velocity circulations of a double-blade pump impeller outlet were calculated with Stodola formula, Weisner formula and Stechkin formula. Simultaneously, the internal flow of impeller for the double-blade pump were measured with PIV technology and average velocity circulations at the 0.8, 1.0 and 1.2 times of design flow were obtained. All the experimental values were compared with the above calculation values at the three conditions. The results show that calculation values of velocity circulations with Weisner formula is close to the experimental values. On the basis of the above, velocity circulations of impeller outlet were corrected. The results of experimental verification show that the corrected calculation errors, whose maximum error is 3.65%, are greatly reduced than the uncorrected calculation errors. The research results could provide good references for establishment of theoretical head and multi-condition hydraulic optimization of double-blade pumps.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 춘계학술대회논문집
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• pp.656-661
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• 2005

An optimization formulation of unconstrained damping treatment on beams is proposed to minimize vibration responses using a numerical search method. The fractional derivative model is combined with RUK's equivalent stiffness approach in order to represent nonlinearity of complex modulus of damping materials with frequency and temperature. The loss factors of partially covered unconstrained beam are calculated by the modal strain energy method. Vibration responses are calculated by using the modal superposition method, and of which design sensitivity formula with respect to damping layout is derived analytically. Plugging the sensitivity formula into optimization software, we can determine optimally damping treatment region that gives minimum forced response under a given boundary condition. A numerical example shows that the proposed method is very effective in minimizing vibration responses with unconstrained damping layer treatment.