• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.243-251
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• 2016

Purpose: This study evaluates the effectiveness of intermittent exotropia vision training through follow up of average 3 years using proprioceptive test (Maindot test). Methods: 35 people (18 men, 17 women) with mean age of 13.48 (${\pm}2.45$) with corrected visual acuity of 0.9 or higher and normal binocular vision and control were observed for changes between before, after, and 3 years following the vision training during the period from 2005 to 2009. Results: After training, the correlation between the changed amount of deviation and PRC(diplopia) value and symptoms was not significant (p>0.05). However, it showed a statistically significant (p<0.001) correlation that change of the binocular proprioceptive sense abilities is decreased subjective symptoms. Conclusions: Binocular proprioceptive sense may be used in variety of purposes and applications such as predictive evaluation of binocular symptoms, binocular function performance evaluation after vision training and prism treatment.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.253-257
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• 2016

Purpose: To determine whether the distance between objects and the size of object are factors to be able to affect dynamic stereoacuity. Methods: Subjects were 37 adults (26 males and 11 females) with an average age of $23.89{\pm}1.76$. Refractive error was fully corrected for all subjects and each visual acuity of them was over 0.9. Three rods test was performed for measurement of stereoacuity. The viewing angles from left rod to right rod were set $5^{\circ}$, $10^{\circ}$, and $15^{\circ}$ and the rod thickness used 7 mm, 14 mm, and 21 mm, respectively. Stereoacuity was repeatedly measured three times in each test condition at 2.5 m distance, and reported the average value of them. Results: When rod thickness was 7 mm or 14 mm, dynamic stereoacuity decreased as the viewing angle increased, and they were significantly decreased (p<0.01) at viewing angles of $10^{\circ}$ and $15^{\circ}$ as compared with that of at $5^{\circ}$, respectively. When rod thickness was 21 mm, dynamic stereoacuity decreased as the viewing angle increased, especially, that of at $15^{\circ}$ decreased significantly (p<0.01) as compared with that of at $5^{\circ}$. The dynamic stereoacuity depending on the rod thickness have an increasing tendency as the rod thickness increased. Conclusions: The viewing angle between objects and the size of viewing object were factors that affect to dynamic stereoacuity.

• Journal of Oriental Neuropsychiatry
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• v.23 no.2
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• pp.99-120
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• 2012

Objectives : The oriental medicine Jangwonhwan, a boiled extract of 12 medicinal herbs/mushrooms, has been prescribed to patients with cognitive dysfunction, as originally described in the Korean medical text, DonguiBogam(amnesia chapter). Recently, a modified formula of Jangwonhwan (LMK02-Jangwonhwan) consisting of seven medicinal plants/mushrooms, was shown to reduce the ${\beta}$-amyloid deposition in the brain of Tg-APPswe/PS1dE9 mouse model for Alzheimer's disease. The toxicity of LMK02-Jangwonhwan was investigated in SD rats, by a daily oral administration for 13 weeks and NOAEL(No observed adverse effect dose), a definite toxic dose and target organ, as well. Methods : Quality control of the tablet form of LMK02-Jangwonhwan was established by estimating the indicative components, Ginsenoside Rg3 of Red Ginseng and Decursin of Angelicagigas Nakai. The toxicity of LMK02-Jangwonhwan was investigated in 6 week old, specific pathogen free (SPF), Sprageu-Dawley rats by oral administration. Each test group consisted of 10 male and 10 female rats. The groups received doses of 500, 1,000 or 2,000 mg/kg/day of test substance for 13 weeks. The clinical signs, death rate, body weight, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemistry, organ weight and pathological changes were examined and compared with those of the control group. Results : The 13-week repeated oral treatment doses didn't result in any specific symptoms or death. There were no significant changes in the rat's weight and food consumption. Further, ophthalmic examination, urinalysis, hematological, serum biochemistry test and organ weight revealed no significant differences. Conclusions : The no-observed-adverse-effect level(NOAEL) of LMK02 for male and female Sprague-Dawley rats was determined as 2,000mg/kg/day and the target organ wasn't confirmed. Because no significant adverse effects were observed, the target organ could not be determined.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.3
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• pp.19-28
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• 2008

Purpose: To understand symptoms and signs in soft contact lens wearers the authors evaluate the attribution of the tear test to the contact lens related symptoms and signs. Methods: Sixty-two healthy soft contact lens wearers (23.95${\pm}$4.38 years old, 18.60${\pm}$16.92 months of prior lens wear) were participated in this study. 3 kinds of tear test and McMonnies' questionnaire test were performed for the soft contact lens wearers and subjective symptoms and objective signs were graded using CCLRU scales during the study period. Results: In this surveys, we found ocular dryness, redness and tiredness are the most common frequent and severe symptoms in soft contact lens wearers. Frequency of the ocular dryness, redness and tiredness are associated with grittiness, burning sensation and foreign body sensation respectively, and severity of the photophobia, foreign body sensation are associated with unstable vision and grittiness and which are associated with score of McMonnies' Questionnaire. Conjunctival redness and limbal redness are major signs but those are not need to be clinical care and rarely occurred corneal and conjunctival staining which are associated with tear break-up-time statistically. Conclusions: Dryness, redness and tiredness are primary common symptoms in Korean soft contact lens wearers. The frequency of those symptoms are increased with the period of soft contact lens wear and those are associated with other symptoms but have no relationship with signs.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.2
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• pp.119-126
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• 2016

Purpose: To analyze the effect of accommodative control and change values between subjective refraction (SR) and auto-refraction (AR) according to application of fogging after accommodative stimulation depending on ametropia type. Methods: Myopic ametropia 76 eyes and hyperopic ametropia 52 eyes participated for this study. SR and AR values measured by three test conditions (Before accommodative stimulation; Before AS, After accommodative stimulation; After AS, and After application of fogging; After AF) were compared, respectively. Results: In myopic eyes, (-)spherical power by SR and AR in After AS test was significantly increased as compared to Before AS test, (-)spherical power in After AF test was decreased to the level of Before AS test. The differences of spherical power between SR and AR were highly measured by SR in After AS test, and highly measured by AR in After AF test, respectively. In hyperopic eyes, (+)spherical power of SR significantly decreased in After AS test compared to Before AS test, more (+)spherical power was detected in After AF test compared to Before AS test. (+)spherical power of AR have no significant difference between Before AS and After AS test, but more (+)spherical power was detected in After AF test compared to Before AS test. The differences of (+)spherical power between SR and AR were significant in all test conditions. Among 52 eyes which were measured as hyperopic ametropia, 7 eyes were measured as myopia by SR in After AS test. In case of AR, 25 eyes among 52 eyes were mismeasured as myopia of ranges from -0.25 D to -1.25 D in Before AS test, 26 eyes in After AS test, and 19 eyes in After AF test were mismeasured as myopia of ranges from -0.25 D to -1.25 D. Conclusions: Regardless of ametropia type, accommodative control by After AF test was effective on both refraction process. However, in auto-refraction for hyperopic eyes, the misdetermined proportion of refractive error's type was high due to consistent accommodative intervention in all test condition. Therefore, in order to obtain an accurate value of refractive errors, full correction should be determined by subjective refraction process after fogging method.

• Journal of Korean Ophthalmic Optics Society
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• v.7 no.2
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• pp.41-45
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• 2002

To study the ametropia and the sort of glasses, especially progressive multifocal lens, for near purpose on Middle aged & Manhood. 500 adults were tested by the object and subject methods. Among the 500 adults, myopia is 22.4%, hyperopia is 61.4%, and emmetropia is 16.2%, respectively. In test of astigmatism, the amount of astigmatism for the age of forty one to under forty five with-the rule is 28%, the amount of astigmatism against-the rule is 43% and the amount of astigmatism with oblique is 11%, respectively. Whereas, the amount of astigmatism for the age of fifty six to under sixty with-the rule is 10%, the amount of astigmatism against-the rule is 71% and the amount of astigmatism with oblique is 19%, respectively. With-the-rule decreased with increasing age while against-the-rule increased with increasing age. The oblique astigmatism relationship to age could not be determined. The ratio of the progressive multifocal lens was 67.3% for male and 35% for female.

• Journal of Korean Ophthalmic Optics Society
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• v.10 no.4
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• pp.329-337
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• 2005

This study investigated prevalence of color vision loss different from children's residence. The study subjects are 3 to 6 grade's children of elementary school in four areas. The blood lead and urinary mercury were analysed using Atomic Absorption Spectroscopy. All of participations' blood lead and urine mercury concentration were below suggested level of concern such as criteria by CDC and ATSDR. Color vision was assessed by the Lanthony D-15 desaturated panel. Color vision loss was quantitatively established by the Color Confusion Index (CCI) and qualitatively classified by type of acquired dyschromatopsia according to Verriest's classification. The prevalence of color vision loss and CCI value for children in industrial area was significantly higher than other areas(p<0.05). However blood lead and urinary mercury concentration level was not correlated to the color vision loss. Therefore we believed that other environmental neurotoxic substance except metal had an effects on color vision loss for children in industrial area.

• Journal of Korean Ophthalmic Optics Society
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• v.10 no.4
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• pp.357-364
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• 2005

To develope the assessment equpiments of an optical system using adaptive optics, we developed the program of wavefront reconstruction for an optical system like eye. We used matlab in order to program the wavefront reconstruction for an optical system and presented the wavefront function of optical system by the zemike polynomials using modal method. To test the developed program, we calculated the zemike coefficient(n=7) of cooke triplet using code V, and compared the wavefront shape and the zemike polynomials using code V to those using the developed program. In this case, the used zemike coefficients were n=2, 3, 4, 5, 6, 7, 8, 9, and 10 and the number of sub-aperture were 1,253. From these results, we know that the reconstructed wavefronts were similar to the wavefront of cooke triplet as n was the larger than 4 and the zemike coefficient was equal to that of cooke triplet as n was 7. The developed program is able to be applied to the core technology to develope the assessment equipment of an optical system using the adaptive optics.

• The Journal of Korean Society for School & Community Health Education
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• v.16 no.2
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• pp.17-31
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• 2015

Objectives: This study aimed to analyze the relationship between metabolic syndrome and cataract in a middle-aged men over the age of 40's by using the data from the 5th Korean National Health and Nutrition Examination Survey(2010~2012). Methods: The subjects for the analysis were comprised of 5,808 patients who were at least 40 years or more with metabolic syndrome and cataract. The comparison between the metabolic syndrome and ophthalmic diseases according to the health demographic characteristics, health behavior and health conditions was analyzed with ${\chi}^2-test$. The complex samples logistic regression analysis was used to calculate the odds ratio of cataract according to the health demographic characteristics, health behavior and health conditions and the combination of the comprising factors of the metabolic syndrome. Results: After controlling the confounding factors, the odds ratio of cataract in the metabolic syndrome group was OR 1.30, which was significantly high (p<0.01). Furthermore, the odds ratio of cataract was significantly high in the case of males, as the age increased, educational level decreased, with exercising habits of less than 3 days a week, sun exposure of at least 5 hours, with hypertension and diabetes (p<0.01). The results of analyzing the odds ratio for the occurrence of cataract with the components of metabolic syndrome were OR 1.36 (concurrent high fasting blood glucose, high triglycerides, low HDL cholesterol), OR 1.63 (concurrent high fasting blood glucose, high triglycerides, high waist circumference) and OR 1.33 (high triglycerides, low HDL cholesterol, high waist circumference), which showed significantly high odds ratio for cataract occurrence (p<0.05). Conclusions: We come to know that the relation between metabolic syndrome and components are associate with cataract. Therefore the thorough management of metabolic syndrome and components is needed to prevent cataract.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.49-53
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• 2007

In this paper, for the purpose of preparing some fundamental data on the development of the eye-health education program and conducting a practical application, the degree of request for the eye-health education were investigated by surveying 304 undergraduate students. The relationship between the degree of request for the eye-health education and sex, the division of major, and the experience of eye-health education was examined by SAS and $X^2$-test of questionnaire. The degree of request of undergraduate students for the eye-health education was as high as 86.51%. There was no statistical significant difference dependence on their experience of the eye-health education or their sex. There was significant difference dependence on their major. Specially, the degree of request of natural science, medical and health science majors was higher than any other majors. Consideration on the eye-health education should be required to meet the request of it.