• Journal of the Korea Society of Computer and Information
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• v.20 no.3
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• pp.29-45
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• 2015

This paper proposes an implementation of SPARQL-DL, which is a query language for OWL ontologies, for query-answering over the OWL ontologies virtually generated from existing RDBs. The proposed SPARQL-DL processor internally translates input SPARQL-DL queries into SQL queries and then executes the translated queries. There are two advantages in the query processing method. First, another repository to store OWL ontologies generated from RDBs is not required. Second, a large ABox generated from an RDB instance is able to be served without using Tableau algorithm based reasoners which have a problem in large ABox reasoning. Our algorithm for query rewriting is designed to create one corresponding SQL query from one input SPARQL-DL query to minimize the overhead by establishing connections with RDBs.

• Journal of Digital Convergence
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• v.13 no.4
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• pp.81-87
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• 2015

This study will show the digital forensic model which fights against cyber-crimes to prepare various cyber-crimes. The digital forensic model will be more useful about the investigation of cyber-crimes and arresting criminals after researching the uses of the digital forensic model and cyber-crime rates in South Korea. This model conduct the standardized data with various languages by the language support system through the digital forensic analyzer. This model will send the data to law enforcement reviewing whether or not we ought to prove criminal charges. Moreover, law enforcement can access the file system to find out admissibility of evidence. And this model simplifies lawful investigation about additional investigation. The data, which is conducted and saved by the digital forensic system, will be helpful to protect against the future crimes because of the data.

• The KIPS Transactions:PartB
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• v.11B no.4
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• pp.509-516
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• 2004

Semantic interpretation of image is incomplete without some mechanism for understanding semantic content that is not directly visible. For this reason, human assisted content-annotation through natural language is an attachment of textual description to image. However, keyword-based retrieval is in the level of syntactic pattern matching. In other words, dissimilarity computation among terms is usually done by using string matching not concept matching. In this paper, we propose a method for computerized semantic similarity calculation In WordNet space. We consider the edge, depth, link type and density as well as existence of common ancestors. Also, we have introduced method that applied similarity measurement on semantic image retrieval. To combine wi#h the low level features, we use the spatial color distribution model. When tested on a image set of Microsoft's 'Design Gallery Line', proposed method outperforms other approach.

• Journal of KIISE:Databases
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• v.33 no.5
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• pp.513-525
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• 2006

Search results of XML keyword search are defined generally as the most specific elements containing all query keywords in the literature. The labels of XML elements and semantic information such as ontology, conceptual model, thesaurus, and so on, are used to improve the preciseness of the search results. This paper presents a hierarchical index for an efficient XML keyword query processing on the condition that returnable search concepts are defined and users' query concepts can be interpreted with the help of the semantic information. The hierarchical index separately stores the XML elements containing a keyword on the basis of the hierarchical relations of the concepts that the XML elements belong to, and makes it possible to obtain least common ancestors, which are candidates for the search results, with selectively reading the elements belonging to the concepts relevant to query concepts and without considering all the combinations of the elements having been read. This paper deals with how to organize the hierarchical index and how to process XML keyword queries with the index. In our experiment with the DBLP XML document and the XML documents in the INEX2003 test set, the hierarchical index worked well.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5281-5286
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• 2013

Purpose: Prostate cancer caused by the abnormal disorderly growth of prostatic acinar cells is the most prevalent cancer of men in western countries. We aimed to screen out differentially expressed genes (DEGs) and explore small molecule drugs for prostate cancer. Materials and Methods: The GSE3824 gene expression profile of prostate cancer was downloaded from Gene Expression Omnibus database which including 21 normal samples and 18 prostate cancer cells. The DEGs were identified by Limma package in R language and gene ontology and pathway enrichment analyses were performed. In addition, potential regulatory microRNAs and the target sites of the transcription factors were screened out based on the molecular signature database. In addition, the DEGs were mapped to the connectivity map database to identify potential small molecule drugs. Results: A total of 6,588 genes were filtered as DEGs between normal and prostate cancer samples. Examples such as ITGB6, ITGB3, ITGAV and ITGA2 may induce prostate cancer through actions on the focal adhesion pathway. Furthermore, the transcription factor, SP1, and its target genes ARHGAP26 and USF1 were identified. The most significant microRNA, MIR-506, was screened and found to regulate genes including ITGB1 and ITGB3. Additionally, small molecules MS-275, 8-azaguanine and pyrvinium were discovered to have the potential to repair the disordered metabolic pathways, abd furthermore to remedy prostate cancer. Conclusions: The results of our analysis bear on the mechanism of prostate cancer and allow screening for small molecular drugs for this cancer. The findings have the potential for future use in the clinic for treatment of prostate cancer.

• Journal of KIISE:Software and Applications
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• v.36 no.1
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• pp.92-108
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• 2009

The Princeton WordNet (PWN), which was developed during last 20 years since the mid 80, aimed at representing a mental lexicon inside the human mind. Its potentiality, applicability and portability were more appreciated in the fields of NLP and KE than in cognitive psychology. The semantic and knowledge processing is indispensable in order to obtain useful information using human languages, in the CMC and HCI environment. The PWN is able to provide such NLP-based systems with 'concrete' semantic units and their network. Referenced to the PWN, about 50 wordnets of different languages were developed during last 10 years and they enable a variety of multilingual processing applications. This paper aims at describing PWN-referenced Korean Wordnet, KorLex 1.5, which was developed from 2004 to 2007, and which contains currently about 130,000 synsets and 150,000 word senses for nouns, verbs, adjectives, adverbs, and classifiers.

• Journal of KIISE
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• v.42 no.12
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• pp.1568-1574
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• 2015

Relation extraction plays a role in for the process of transforming a sentence into a form of knowledge base. In this paper, we focus on predicates in a sentence and aim to identify the relevant knowledge base properties required to elucidate the relationship between entities, which enables a computer to understand the meaning of a sentence more clearly. Distant Supervision is a well-known approach for relation extraction, and it performs lexicalization tasks for knowledge base properties by generating a large amount of labeled data automatically. In other words, the predicate in a sentence will be linked or mapped to the possible properties which are defined by some ontologies in the knowledge base. This lexical and ontological linking of information provides us with a way of generating structured information and a basis for enrichment of the knowledge base.

• Journal of Microbiology and Biotechnology
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• v.32 no.3
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• pp.365-377
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• 2022

Mammalian target of rapamycin (mTOR) is a serine-threonine kinase member of the cellular phosphatidylinositol 3-kinase (PI3K) pathway, which is involved in multiple biological functions by transcriptional and translational control. mTOR is a downstream mediator in the PI3K/Akt signaling pathway and plays a critical role in cell survival. In cancer, this pathway can be activated by membrane receptors, including the HER (or ErbB) family of growth factor receptors, the insulin-like growth factor receptor, and the estrogen receptor. In the present work, we congregated an electronic network of mTORC1 built on an assembly of data using natural language processing, consisting of 470 edges (activations/interactions and/or inhibitions) and 206 nodes representing genes/proteins, using the Cytoscape 3.6.0 editor and its plugins for analysis. The experimental design included the extraction of gene expression data related to five distinct types of cancers, namely, pancreatic ductal adenocarcinoma, hepatic cirrhosis, cervical cancer, glioblastoma, and anaplastic thyroid cancer from Gene Expression Omnibus (NCBI GEO) followed by pre-processing and normalization of the data using R & Bioconductor. ExprEssence plugin was used for network condensation to identify differentially expressed genes across the gene expression samples. Gene Ontology (GO) analysis was performed to find out the over-represented GO terms in the network. In addition, pathway enrichment and functional module analysis of the protein-protein interaction (PPI) network were also conducted. Our results indicated NOTCH1, NOTCH3, FLCN, SOD1, SOD2, NF1, and TLR4 as upregulated proteins in different cancer types highlighting their role in cancer progression. The MCODE analysis identified gene clusters for each cancer type with MYC, PCNA, PARP1, IDH1, FGF10, PTEN, and CCND1 as hub genes with high connectivity. MYC for cervical cancer, IDH1 for hepatic cirrhosis, MGMT for glioblastoma and CCND1 for anaplastic thyroid cancer were identified as genes with prognostic importance using survival analysis.

• Journal of KIISE:Software and Applications
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• v.36 no.3
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• pp.187-199
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• 2009

With the advent of Web 2.0, OpenAPIs are becoming an increasing trend to emphasize Web as platform recently. OpenAPIs are used to combine services and generate new services by mashup. However because the standard documents for OpenAPIs do not exist, it may restrict the use of OpenAPIs. Previous studies of OpenAPIs mashup have been limited to tool design or language definition for service combination rather than dynamic composition. On the other hand, Web services that are a software technology implementing SOA provide standard documents such as WSDL to explain each service, UDDI to register it, and SOAP to transfer messages. Thus Web applications can interpret and execute services by using these technologies. Recent works have also been performed to provide semantic features and dynamic composition for SOA. If a dynamic and systematic approach is provided to combine Web services and OpenAPIs, Web applications can provide users with diverse services. In this study, we present a SOA based framework for mashup of OpenAPIs and Web services. The framework supports dynamic composition of OpenAPIs and Web services, where the process of composite services is described in OWL-S. A prototype is provided to validate our framework. The framework is expected to add diversity to typical Web services.

• KIPS Transactions on Software and Data Engineering
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• v.1 no.3
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• pp.159-168
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• 2012

Relation in the new IT environment, such as the SNS, Cloud, Web3.0, has become an important factor. And these relations generate a transaction. However, existing relational database and graph database does not processe graph structure representing the relationships and transactions. This paper, we propose the technique that can be processed concurrently graph structures and transactions in a scalable complex network system. The proposed technique simultaneously save and navigate graph structures and transactions using the Topic Maps data model. Topic Maps is one of ontology language to implement the semantic web(Web 3.0). It has been used as the navigator of the information through the association of the information resources. In this paper, the architecture of the proposed technique was implemented and design using Cassandra - one of column type NoSQL. It is to ensure that can handle up to Big Data-level data using distributed processing. Finally, the experiments showed about the process of storage and query about typical RDBMS Oracle and the proposed technique to the same data source and the same questions. It can show that is expressed by the relationship without the 'join' enough alternative to the role of the RDBMS.