• Title/Summary/Keyword: on-off control

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Circulating Levels of Adipocytokines as Potential Biomarkers for Early Detection of Colorectal Carcinoma in Egyptian Patients

  • Zekri, Abdel-Rahman N;Bakr, Yasser Mabrouk;Ezzat, Maali Mohamed;Zakaria, Mohamed Serag Eldeen;Elbaz, Tamer Mahmoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.6923-6928
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    • 2015
  • Background: Early detection of various kinds of cancers nowadays is needed including colorectal cancer due to the highly significant effects in improving cancer treatment. The aim of this study was to evaluate the potential value of adiponectin, visfatin and resistin as early biomarkers for colorectal cancer patients. Materials and Methods: Serum levels of adiponectin, visfatin and resistin were measured by a sandwich-enzyme-linked (ELISA) assay technique in 114 serum samples comprising 34 patients with colorectal cancer (CRC), 27 with colonic polyps (CP), 24 with inflammatory bowel disease (IBD) and 29 healthy controls. The diagnostic accuracy of each serum marker was evaluated using receiver-operating characteristic (ROC) curve analysis. Results: The mean concentration of adiponectin was significantly higher in CRC and CP groups than IBD and control groups (P-value <0.05). Also the mean concentration of serum resistin was significantly elevated in the IBD and control groups compared to CRC and CP groups (P-value = 0.014). However, no significant difference was noted in patients of the CRC and CP groups. On the other hand, the mean concentration of visfatin was significantly elevated in CRC and control groups compared to CP and IBD groups (P-value = 0.03). ROC analysis curves for the studied markers revealed that between CRC and IBD groups serum level of adiponectin had a sensitivity of 76.7% and a specificity of 76% at a cut off value of 3940, +LR being 3.2 and -LR 0.31 with AUC 0.852, while serum level of adiponectin between CP and IBD had a sensitivity of 77.8% and a specificity of 75% at a cut off value of 3300, with +LR=3.11 and -LR = 0.3 with AUC 0.852. On the other hand the serum level of visfatin between CRC and CP groups had a sensitivity of 65.5% and a specificity of 66.7 at a cut off value of 2.4, +LR being 1.67 and -LR 0.52 with AUC 0.698. Also the serum level of resistin had a sensitivity of 62.5% and a specificity of 70.3% at a cut off value of 24500, with +LR=2.1 and -LR = 0.53 with AUC 0.685 between control and other groups. On the other hand by comparing control vs CP groups resistin had a sensitivity of 81.8% and a specificity of 70.8% at a cut off value of 17700, with +LR=2.8 and -LR = 0.26 with AUC 0.763 while visfatin had a sensitivity of 68.2% and a specificity of 70.8% at a cut off value of 2.7, with +LR=2.34 and -LR = 0.0.45 with AUC 0.812. Conclusions: These findings support potential roles of adiponectin, visfatin and resistin in early detection of CRC and discrimination of different groups of CRC, CP or IBD patients from normal healthy individuals.

Study on Triaxiality Velocity of COMS induced by Wheel Off-loading

  • Park, Young-Woong;Kim, Dae-Kwan;Lee, Hoon-Hee
    • Bulletin of the Korean Space Science Society
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    • 2008.10a
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    • pp.36.3-36.3
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    • 2008
  • KARI (Korea Aerospace Research Institute) is going to launch a Communication, Ocean and Meteorological Satellite (COMS) at summer of 2009. It will be first thing to be developed for a geostationary satellite through domestic technology. Of course, KARI has performed this development program with EADS Astrium in France since 2005. COMS has the non-symmetric configuration that the solar array is only attached on the south panel. Due to the configuration, momentum of satellite will be rapidly accumulated induced by solar pressure and then 3 wheels of large momentum are located on roll-yaw plane for attitude control. Therefore, to prevent the saturation of wheel momentum, wheel off-loading will be performed two times per day during 10 minutes for each one. At the moment, translation movement on 3-axes direction appears because of using thrusters. In this paper, strategy of the wheel off-loading and triaxiality which is the translation effect on 3-axes are introduced. Consequently, the result of optimized triaxiality considering the wheel off-loading strategy is summarized.

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A Novel Soft Switching PWM·PFC AC·DC Boost Converter

  • Sahin, Yakup
    • Journal of Electrical Engineering and Technology
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    • v.13 no.1
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    • pp.256-262
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    • 2018
  • This study introduces a novel Soft Switching (SS) Pulse Width Modulated (PWM) AC-DC boost converter. In the proposed converter, the main switch is turned on with Zero Voltage Transition (ZVT) and turned off with Zero Current Transition (ZCT). The main diode is turned on with Zero Voltage Switching (ZVS) and turned off with Zero Current Switching (ZCS). The auxiliary switch is turned on and off with ZCS. All auxiliary semiconductor devices are turned on and off with SS. There is no extra current or voltage stress on the main semiconductor devices. The majority of switching energies are transferred to the output by auxiliary transformer. Thus, the current stress of auxiliary switch is significantly reduced. Besides, the proposed converter has simple structure and ease of control due to common ground. The theoretical analysis of the proposed converter is verified by a prototype with 100 kHz switching frequency and 500 W output power. Furthermore, the efficiency of the proposed converter is 98.9% at nominal output power.

A Study on the Frequency response charcteristics of Hydraulic Equipment using High speed on-off valve (고속전자밸브를 사용한 유압장치의 주파수응답특성에 관한 연구)

  • Huh, Jun-Young;Wennmacher, G.
    • Journal of the Korean Society for Precision Engineering
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    • v.12 no.2
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    • pp.79-86
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    • 1995
  • Frequency response method is used to design hydraulic servo systems and improve its performance. In this study a method is proposed to get simply the frequency response of the electro-hydraulic servo system which use PWM controlled high-speed on-off valves. Firstly, the describing function of the PWM element is derived and tested. It is found that the character- istic of PWM element could be approximated to a saturation characteristic in the range of allowable frequency. And the dynamic characteristic of the valve-cylinder system could be negligible. The working characteristic of high-speed on-off valve is considered as time delay. So simulation is performed in the basis of the reconstructed block diagram. And this method is verified by experiments.

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A Study on Shape Optimization of Electro-Magnetic Proportional Solenoid (비례솔레노이드 형상 최적설계에 관한 연구)

  • Yun S.N.;Ham Y.B.;Kang J.H.
    • Transactions of The Korea Fluid Power Systems Society
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    • v.2 no.3
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    • pp.1-5
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    • 2005
  • There are two types of solenoid actuator for force and position control of the fluid power system. One is an on-off solenoid actuator and the other is an electro-magnetic proportional actuator. They have some different characteristics for attraction force according to solenoid shape. Attraction force of the on-off solenoid actuator only depends on flux density. And the stroke-force characteristics of the proportional solenoid actuator are determined by the shape of the control cone. In this paper, steady state characteristics of the solenoid actuator for electro-hydraulic proportional valve determined by the shape of control cone are analyzed using finite element method and it is confirmed that the proportional solenoid actuator has a constant attractive force in the control region independently on the stroke position. And the shape of control cone is optimized using 1+1 evolution strategy to get a constant force. In the optimization algorithm, control cone length, thickness and taper length are used as a design parameter.

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U-healthcare Based System for Sleeping Control and Remote Monitoring (u-헬스케어기반의 수면제어 및 원격모니터링 시스템)

  • Kim, Dong-Ho;Jeong, Chang-Won;Joo, Su-Chong
    • Journal of Internet Computing and Services
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    • v.8 no.1
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    • pp.33-45
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    • 2007
  • Using switches and sensors informing the current on or off state, this paper suggests a sleeping control and remote monitoring system that not only can recognize the sleeping situations but also can control for keeping an appropriate sleeping situation remotely, And we show an example that this system is applied to the healthcare sleeping mat, Our system comprises the following 3 parts: a part for detecting the sleeping situations, a part for extracting sensing data and sending/receiving the relating situated data, and a part controlling and monitoring the all of sleeping situations. In details, in order to develop our system, we used the touch and pressure-sensitive sensors with On/Off functions for a purpose of the first part, The second part consists of the self-developed embedded board with the socket based communication as well as extracting real-time sensing data. And the third part is implemented by service modules for providing controlling and monitoring functions previously described. Finally, these service modules are implemented by the TMO scheme, one of real-time object-oriented programming models and the communications among them is supported using the TMOSM of distributed real-time middleware.

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Effects of Vth adjustment ion implantation on Switching Characteristics of MCT(MOS Controlled Thyristor) (문턱전압 조절 이온주입에 따른 MCT (MOS Controlled Thyristor)의 스위칭 특성 연구)

  • Park, Kun-Sik;Cho, Doohyung;Won, Jong-Il;Kwak, Changsub
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.5
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    • pp.69-76
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    • 2016
  • Current driving capability of MCT (MOS Controlled Thyristor) is determined by turn-off capability of conducting current, that is off-FET performance of MCT. On the other hand, having a good turn-on characteristics, including high peak anode current ($I_{peak}$) and rate of change of current (di/dt), is essential for pulsed power system which is one of major application field of MCTs. To satisfy above two requirements, careful control of on/off-FET performance is required. However, triple diffusion and several oxidation processes change surface doping profile and make it hard to control threshold voltage ($V_{th}$) of on/off-FET. In this paper, we have demonstrated the effect of $V_{th}$ adjustment ion implantation on the performance of MCT. The fabricated MCTs (active area = $0.465mm^2$) show forward voltage drop ($V_F$) of 1.25 V at $100A/cm^2$ and Ipeak of 290 A and di/dt of $5.8kA/{\mu}s$ at $V_A=800V$. While these characteristics are unaltered by $V_{th}$ adjustment ion implantation, the turn-off gate voltage is reduced from -3.5 V to -1.6 V for conducting current of $100A/cm^2$ when the $V_{th}$ adjustment ion implantation is carried out. This demonstrates that the current driving capability is enhanced without degradation of forward conduction and turn-on switching characteristics.

A Study of Ramp Metering System Using Off-ramp Exit Percentage (램프 진출교통량 비율을 이용한 램프미터링 운영방안 연구)

  • Kang, Woojin;Kim, Youngchan;Lee, Minhyoung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.6
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    • pp.102-115
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    • 2016
  • In this study, a scheme of ramp metering that uses Off-ramp Exit Percentage instead of the O/D table required for systems of integrated control of ramps at the target freeway segment is presented. The segment from Gyeyang IC to Jangsu IC on the Seoul Outer Ring Expressway was selected for the study because the segment frequently shows large volume of traffic on the short distance between the two ICs requiring an integrated on-ramp control by taking the traffic situation on an entire expressway into account despite an unavailability of O/D data. Thus the information of Off-ramp Exit Percentage at each IC were collected instead of securing the O/D table through actual survey, and the congestion on the segment was analyzed to identify the validity of the use of off-ramp traffic instead of O/D data. In addition, the scheme of ramp metering that exploits the off-ramp traffic information was prepared through simulations conducted in a way supporting the traffic control for respective access roads thereof by taking traffic situations and queues on each ramp into account. The results obtained from the simulation analyses revealed an improved level of travel speed and traffic volume on the main line and validated the use of off-ramp traffic instead of the O/D table for the ramp metering.

Adaptive Blowing Control Algorithm for Autonomous Control of Underwater Flight Vehicle (수중 비행체의 자율제어를 위한 적응 부상 제어 알고리즘)

  • Kim, Hyun-Sik
    • Journal of the Korean Institute of Intelligent Systems
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    • v.18 no.4
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    • pp.482-487
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    • 2008
  • In case of flooding, the underwater flight vehicle (UFV) executes the blowing by blowing ballast tanks off using high pressure air (HPA), while it also uses control planes and a propulsion unit to reduce the overshoot depth caused by a flooding and blowing sequence. However, the conventional whole HPA blow-off method lets the body on the surface after blowing despite slight flooding. This results in the unnecessary mission failure or body exposure. Therefore, it is necessary to keep the body at the near surface by the blowing control while reducing the overshoot depth. To solve this problem, an adaptive blowing control algorithm, which is based on the decomposition method expanding the expert knowledge in depth control and the adaptive method using fuzzy basis function expansion (FBFE), is proposed. To verify the performance of the proposed algorithm, the blowing control of UFV is performed. Simulation results show that the proposed algorithm effectively solves the problems in the UFV blowing control system online.