• Journal of Periodontal and Implant Science
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• 제44권1호
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• pp.25-32
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• 2014

Purpose: Periodontitis is an infectious disease caused predominantly by gram-negative anerobes. The host inflammatory response to these bacteria causes alveolar bone loss that is characterized as periodontitis. Omega-3 fatty acids (${\omega}$-3 FAs) have anti-inflammatory properties, thus have been used to treat some chronic inflammatory diseases such as cardiovascular disease and rheumatoid arthritis. We aimed to evaluate the effect of dietary supplementation with ${\omega}$-3 FAs as a host modulating agent in patients with chronic periodontitis. Methods: Sixty otherwise healthy subjects with moderate and severe chronic periodontitis were enrolled in our randomised, double-blind, placebo-controlled trial. The control group (CG, n=30) was treated with scaling and root planing (SRP) and given a placebo; the treatment group (TG, n=30) was treated with SRP and dietary supplementation of ${\omega}$-3 FAs (one 300 mg tablet daily for 12 weeks). Periodontal clinical parameters and serum C-reactive protein (CRP) levels were evaluated in all patients at baseline, a 6-week and 12-week period after treatment. Results: A significant reduction in the gingival index, sulcus bleeding index, pocket depth, and clinical attachment level was found in the TG compared to the CG at a 12-week period. However, no statistically significant changes in serum CRP levels were found. Conclusions: Our findings suggest that ${\omega}$-3 FAs can successfully reduce gingival inflammation, pocket depth, and attachment level gain. Dietary supplementation with ${\omega}$-3 FAs may have potential benefits as a host modulatory agent in the prevention and/or C management of chronic periodontitis.

• 한국가정과학회지
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• 제10권1호
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• pp.81-87
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• 2007

This study was designed to evaluate the balance of fatty acids for the Korean style broiled beef and pork ingredient of the rate of mixture oil with sesame oil, soybean oil and perilla oil, by self-developed computer program. Each 3 kinds of Korean style broiled beef and pork by the rate of mixure oil with sesame oil, soybean oil and perilla oil, were evaluated by using the self-developed computer program. Contents of calories were 415.6kcal in Korean style broiled beef, 656.3 kcal in Korean style broiled pork. The mean of protein were 41.35g, Korean style broiled beef, 32.66g, Korean style broiled pork. The ratio of C/P/F ratio of Korean style broiled beef and pork, 21/ 40/ 39, 10/ 20/ 70. The mean P/ M/ S of fatty acids in Korean style broiled beef and pork ratio was similar $0.4{\sim}0.5/\;1.4{\sim}1.5/\;1$. The ${\omega}6/{\omega}3$ ratio of fatty acids of Korean style broiled beef and pork using sesame oil was 54.3, 56.9 much higher than desirable $level(4{\sim}8)$. But the ${\omega}6/{\omega}3$ ratio of fatty acids of Korean style broiled beef using mixture oil with sesame oil, soybean oil and perilla oil were 4.6, 4.2 desirable $level(4{\sim}8)$, Korean style broiled pork using mixture oil with sesame oil, soybean oil and perilla oil were 3.0, 6.2. It means the ${\omega}6/{\omega}3$ ratio of fatty acids of Korean style broiled beef and pork was improved of desirable level respectively by using the mixture oil with sesame oil, soybean oil and perilla oil, than using sesame oil.

• Journal of Nutrition and Health
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• 제26권6호
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• pp.661-671
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• 1993

The change in fatty acid composition in brain tissue of the second generation rats(Sprague-Dawley strain) was studied using four different fat diets(Corn oil=CO, Soybean oil=SO, Perilla oil=PO, Fish oil=FO, 10% by Wt). The experimental diets were started from pregnancy in four different groups, each consisting of 9 rats. The seound generation rats were fed the same diet as their mothers. Animals were anesthetized with ether at 0, 3, 9 & 16 weeks of age. Whole brains were dissected out, brain tissues were, then, homogenized and lipids were extracted from brain tissues. The fatty acid compositions were measured after methylation by gas-liquid chromatography at 0, 3, 9 and 16 weeks of age of offspring. The changes in the relative concentrations of polyunsaturated fatty acids(PUFA) or more specifically docosahexaenoic acid(22 : 6, $\omega$3, DHA), the major $\omega$3 fatty acid component in rat brain at different age were similar to changes in the amount of DNA in brain tissue showing the maximum value during the lactation. The changes in saturated fatty acid(SFA) content showed a contrasting patten to those of PUFA, while monounsaturated fatty acid(MUFA) increased steadily throughout the experimental period. At birth, the relative concentrations of $\omega$3 series fatty acids the relative concentrations of PUFA, MUFA and SFA converged to very similar values respectively regardless of the dietary fatty acid compositions. In brain tissue, it is of value to note that while changes in relative concentrations of linoleic acid (18 : 2, $\omega$6, LA) and arachidonic acid(20 : 4, $\omega$6, AA) showed a precursor-product-like relationship, $\alpha$-linolenic acid(18 : 3, $\omega$3, $\alpha$-LnA) and DHA showed a different pattern. Even when the $\omega$3 fatty acid content in very low in maternal diet(CO), the second generation rat brain tissues appeared to secure DHA content, suggesting an essential role of this fatty acid in the brain. The fact that a large amount of $\alpha$-LnA in the maternal diet did not have a significant effect on the second generation rat brain $\alpha$-LnA content, indicated that DHA seemed essential component for the brain development in our experimental condition. In all groups, the relative content of $\alpha$-LnA in the brain tissues remained relatively constant throughout the experimental period at the very low level. The study of the specific concentrations and essential role(s) of DHA in each parts of brain tissue is needed in more details.

• 충청수학회지
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• 제33권2호
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• pp.271-285
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• 2020

In this paper, we have introduced a new type of covering property ${\beta}^t_{({\omega}_r,s)}$-closedness, stronger than $P^t_{({\omega}_r,s)}$-closedness [3] in terms of (r, s)-β-open sets [9] and β-ω_t-closures in bitopological spaces along with its several characterizations via filter bases and grills [15] and various properties. Further grill generalizations of ${\beta}^t_{({\omega}_r,s)}$-closedness (namely, ${\beta}^t_{({\omega}_r,s)}$-closedness modulo grill) and associated concepts have also been investigated.

• 대한수학회보
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• 제55권3호
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• pp.957-965
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• 2018

We study the class $C{\mathcal{V}} ({\Omega})$ of analytic functions f in the unit disk ${\mathbb{D}}=\{z{\in}{\mathbb{C}}$ : ${\mid}z{\mid}$ < 1} of the form $f(z)=z+{\sum}_{n=2}^{\infty}a_nz^n$ satisfying $$1+\frac{zf^{{\prime}{\prime}}(z)}{f^{\prime}(z)}{\in}{\Omega},\;z{\in}{\mathbb{D}}$$, where ${\Omega}$ is a convex and proper subdomain of $\mathbb{C}$ with $1{\in}{\Omega}$. Let ${\phi}_{\Omega}$ be the unique conformal mapping of $\mathbb{D}$ onto ${\Omega}$ with ${\phi}_{\Omega}(0)=1$ and ${\phi}^{\prime}_{\Omega}(0)$ > 0 and $$k_{\Omega}(z)={\displaystyle\smashmargin{2}{\int\nolimits_{0}}^z}{\exp}\({\displaystyle\smashmargin{2}{\int\nolimits_{0}}^t}{\zeta}^{-1}({\phi}_{\Omega}({\zeta})-1)d{\zeta}\)dt$$. Let $z_0,z_1{\in}{\mathbb{D}}$ with $z_0{\neq}z_1$. As the first result in this paper we show that the region of variability $\{{\log}\;f^{\prime}(z_1)-{\log}\;f^{\prime}(z_0)\;:\;f{\in}C{\mathcal{V}}({\Omega})\}$ coincides wth the set $\{{\log}\;k^{\prime}_{\Omega}(z_1z)-{\log}\;k^{\prime}_{\Omega}(z_0z)\;:\;{\mid}z{\mid}{\leq}1\}$. The second result deals with the case when ${\Omega}$ is the right half plane ${\mathbb{H}}=\{{\omega}{\in}{\mathbb{C}}$ : Re ${\omega}$ > 0}. In this case $CV({\Omega})$ is identical with the usual normalized class of convex univalent functions on $\mathbb{D}$. And we derive the sharp upper bound for ${\mid}{\log}\;f^{\prime}(z_1)-{\log}\;f^{\prime}(z_0){\mid}$, $f{\in}C{\mathcal{V}}(\mathbb{H})$. The third result concerns how far two functions in $C{\mathcal{V}}({\Omega})$ are from each other. Furthermore we determine all extremal functions explicitly.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회B
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• pp.2171-2176
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• 2007

The 3-omega (3-${\omega}$) method is utilized to measure the thermal conductivity of nanofluids. A metal line heater on a silicon nitride membrane bridge structure is microfabricated by a bulk silicon etching method. Localized measurement of the thermal conductivity within the nanofluids droplet is possible by the fabricated 3-${\omega}$ sensor. Time varying AC temperature amplitudes and thermal conductivities are measured to check the stability of the nanofluids containing multi-wall carbon nanotubes (MWCNTs). Stabilities of MWCNT nanofluids prepared with different chemical treatments are compared. Acid treated MWCNT showed best dispersion stability in water while MWCNTs dispersed in water with surfactants such as Gum Arabic and Sodium dodecyl benzene sulfate showed clear sign of gravity dependence.

• 한국해양공학회지
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• 제13권2호통권32호
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• pp.108-115
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• 1999

To study measurement of coated steel corrosion in mortar, a transient electro-magnetic(TEM) method was adapted. The sensors were made of enamelled wire with diameter of 0.25mm(transmitter), 0.1mm(receiver) and the secondary electro motive force(EMF) was measured with SIROTEMIII. The sensors configuration was used as in loop configuration. After coated steels were corroded by the salt spray during 3, 7, 15, 25days, they were embedded in mortar which were made from sand : cement : water ratio of 2 : 1 :0.5. To investigate coated steel corrosion in mortar, the sensors were used. ( sensorl - $T_x$ : $4{\Omega}$, $R_x$ : $10{\Omega}$, $3{times}3cm$, sensor2 - $T_x$ : $8{\Omega}$, $R_x$ : $10{\Omega}$, $3{times}3cm$, sensor3 - $T_x$ : $4{\Omega}$, $R_x$ : $10{\Omega}$, $6{times}6cm$, sensor4 - $T_x$ : $8{\Omega}$, $R_x$ : $10{\Omega}$, $6{times}6cm$). The obtained results showed that the secondary EMF was decreased with specimens of 3, 7days corroded coationg steel in mortar and then increased with specccimens of 15, 25days corroded one. And it was confirmed that measurement of coated steel corrosion in mortar by a transient electro-magnetic(TEM) method is possible.

• Preventive Nutrition and Food Science
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• 제7권3호
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• pp.265-272
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• 2002

In this study, we examined the effects of dietary fatty acids on the fatty acid composition of phospholipid fractions in regions of the brain and on behavioral development in rats. The Sprague Dawley rats were fed the experimental diets 3~4 wks prior to the conception. Experimental diets consisted of 10% fat(wt/wt) which were from either safflower oil (SO, poor in $\omega$3 fatty acids), mixed oil MO, P/M/S ratio : 1:1.4:1, $\omega$6/$\omega$3 ratio = 6.3), or mixed oil supplemented with vitamin E (+500 mg/kg diet). At 3 and 9 weeks of age, frontal cortex (FC), corpus striatum (CS), hippocampus (H), and cerebellum (CB) were dissected from the whole brain. The fatty acid content was determined in the different phospholipid fractions: phosphatidylcholine (PC), phosphatidyl-serine (PS), and phosphatidylethanolamine (PE) in the rat brain regions. In the visual discrimination test, the order of the cumulative errors made in Y-water maze test were SO > MO > ME. This suggested that the balanced diet supplemented with vitamin I had the most beneficial effect on learning ability. The overall characteristics of correlation between fatty acids and behavior development were that the frequency of cumulative errors were negatively correlated significantly with monounsaturated fatty acids (MUFAs), ie., 18:1 $\omega$9 and 22:1 $\omega$9. Docosa-hexaenoic acid (22:6 $\omega$3) of PS in frontal cortex (FC) was negatively correlated with the number of errors made in the Y-water maze test.22:5 $\omega$6 PS in hippocampus (H), PC and PE in corpus striatum (CS), PC in cerebellum (CB) were positively correlated with cumulative errors. And these errors were negatively correlated with 20:4 $\omega$ 6 of PE in corpus striatum (CS) and PC in cerebellum (CB). Especially, O1eic acid (18:1 u 9) in all phospholipid fractions (PC, PS, PE) of hippocampus was negatively correlated with the number of errors. These findings demonstrate that the MUFAs were might be essential for proper brain development, especially in hippocampus which is generally thought to be the regions of memory and learning.

• 센서학회지
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• 제11권6호
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• pp.358-364
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• 2002

본 논문에서는 백금박막 온도센서의 $0^{\circ}C$, $100{\Omega}$ 세팅을 위해 355nm 파장을 갖는 자외선 레이저를 이용하였다. 국제적으로 온도센서의 A-class 기준오차는 $0^{\circ}C$에서 ${\pm}0.060{\Omega}$이다. 실제적으로 이 값은 $0.15^{\circ}C$이하에 해당하는 오차로 저항체 제작시 고정밀 가공 기술을 필요로 한다. 가공에 이용된 355nm DYP(Diode-Pumped YAG) 레이저는 power : 37mW, rep rate 주파수 : 200Hz 그리고 bite size : $7.5{\mu}m$에서 $1{\sim}1.5{\mu}m$ 두께의 백금박막을 가장 안전하게 가공할 수 있었으며, 가공선폭은 $10{\mu}m$ 안팎임을 확인하였다. 그리고 사진식각 공정기술을 이용하여 제작된 $2"{\times}2"$ 기판내의 96개(4 by 24) 저항체는 상온 $25^{\circ}C$에서 $79{\sim}90{\Omega}$ : 42.7%, $91{\sim}102{\Omega}$ : 57.3%의 비율로 각각 제작되어졌다. $109.73{\Omega}$를 목표 값으로 $25^{\circ}C$에서 자외선 레이저를 이용하여 가공한 결과, 82.3%가 가공오차가 ${\pm}0.03{\Omega}$이하에 들어왔으며 나머지 17.7%도 국제규격 A-Class내인 ${\pm}0.06{\Omega}$내에 포함되었다.

• 대한한방소아과학회지
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• 제31권3호
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• pp.37-45
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• 2017

Objectives Hataedock is an orally-administered herbal extract that used to treat toxic heat and help excrete meconium accumulates in the fetus from pregnancy. This study compared the effects of Hataedock using the extract of Douchi and omega-3 to control inflammation in the colonic mucosa. Methods NC/Nga mice were divided into three groups; Control group (no treatment), FGT group (given the extract of Douchi), and O3T group (given omega-3). The 3-week-old mouse from each group were given the extract of Douchi and omega-3. After 2 weeks, the colonic mucosa tissues of the mice were observed via Immunohistochemical staining for IL-4, IL-13, CD40, $Fc{\varepsilon}RI$, $p-I{\kappa}B$, EGF in the intestinal mucosa. Results In both FGT and O3T group, IL-4, IL-13, STAT-6 levels and CD40-positive reactions were decreased. However, EGF-positive responses were increased. FGT group showed 35% decrease in IL-4, 45% decrease in IL-13, 48% decrease in CD40, 50% decrease in $Fc{\varepsilon}RI$, 54% decrease in $p-I{\kappa}B$, 52% increase in EGF compared to the control group. O3T group also showed 14% decrease in IL-4, 23% decrease in IL-13, 22% decrease in CD40, 29% decrease in $Fc{\varepsilon}RI$, 41% decrease in $p-I{\kappa}B$, 39% increase in EGF compared to the control group. Conclusions Both early administration of Douchi extract and omega-3 were effective in regulating Th2, relieving inflammation and developing colonic mucosal tissues. Hataedock with Douchi extract may be more effective in modulating immune system in colonic mucosa than omega-3.