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Treatment of Atopic Dermatitis (아토피피부염의 치료)

  • Han, Tae-Young;Na, Chan Ho;Lee, Ji Hyun;Kim, Hye One;Park, Chang Ook;Seo, Young Joon;Son, Sang Wook;Shin, Min Kyung;Ahn, Ji Young;Lee, Yang Won;Jang, Yong Hyun;Park, Young Lip;Lew, Bark Lynn
    • Korean journal of dermatology
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    • v.56 no.10
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    • pp.581-593
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    • 2018
  • Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects both children and adults. AD is the cause of considerable morbidity including severe pruritus and impaired quality of life. Treatments for active disease include avoidance of triggering factors, barrier repair, topical medications including topical corticosteroids (TCs) and topical calcineurin inhibitors (TCIs), phototherapy, antibacterial agents, and systemic immunosuppressants including cyclosporine. Until recently, the only Food and Drug Administration (FDA)-approved systemic treatment options for patients with moderate-to-severe AD were steroids and cyclosporine. Systemic steroids are not recommended by current guidelines and are commonly associated with disease rebound. Instead, clinicians choose from several off-label immunosuppressants. In 2018, the Korean FDA approved dupilumab for adults with moderate-to-severe AD whose disease is not adequately controlled with topical therapies. The implementation of treatment guidelines for AD is challenging. Herein, we review the several treatment modalities for AD and recommend a treatment algorithm.

Comparison of particle collection characteristics in a wire-cylindrical wet electrostatic precipitator with and without a water film (와이어-실린더형 습식 전기집진기의 수막 유무에 따른 집진 특성 비교)

  • Woo, Chang Gyu;Cho, Won Ki;Kim, Hak-Joon;Kim, Yong-Jin;Han, Bangwoo
    • Particle and aerosol research
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    • v.14 no.4
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    • pp.89-95
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    • 2018
  • People's environmental concerns for fine particles in Korea lead to the strong necessity of improving the performance of environmental control systems. Wet electrostatic precipitators (ESPs) are considered as one of the alternatives to overcome the limit of previous dry ESPs, the re-entrainment of collected particles during rapping and back corona problem for high electrical resistivity dusts etc. In this study, a wire-cylindrical ESP with a thin water film has been developed. Particle collection characteristics were compared in the ESP with operations of water film on and off. Particle collection efficiencies at various applied voltages as well as voltage-current curves were almost the same in the ESP with and without a water film. Particle collection performance for PM1.0, PM2.5 and PM10 in the wet ESP with a water film was constantly maintained with operation time even in the high dust loading environment. This results indicate that a uniform water film in our wet ESP was successfully formed with a very thin layer without any dry spot and therefore could continuously clean the collected particles on the inner wall of the ESP without any performance degradation.

Flexible Liquid Crystal Displays Using Liquid Crystal-polymer Composite Film and Colorless Polyimide Substrate

  • Kim, Tae Hyung;Kim, Minsu;Manda, Ramesh;Lim, Young Jin;Cho, Kyeong Jun;Hee, Han;Kang, Jae-Wook;Lee, Gi-Dong;Lee, Seung Hee
    • Current Optics and Photonics
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    • v.3 no.1
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    • pp.66-71
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    • 2019
  • Application of liquid crystal (LC) materials to a flexible device is challenging because the bending of LC displays easily causes change in thickness of the LC layer and orientation of LCs, resulting in deterioration in a displayed image quality. In this work, we demonstrate a prototype device combining a flexible polymer substrate and an optically isotropic LC-polymer composite in which the device consists of interdigitated in-plane switching electrodes deposited on a flexible colorless polyimide substrate and the composite consisting of nano-sized LC droplets in a polymer matrix. The device can keep good electro-optic characteristics even when it is in a bending state because the LC orientation is not disturbed in both voltage-off and -on states. The proposed device shows a high potential to be applicable for future flexible LC devices.

Dismantling and Reconstruction of Family Relationship as Revealed in "My Golden Life" (<황금빛 내 인생>에서 나타난 가족관계 해체와 재구성)

  • Kim, Joon
    • Journal of Digital Convergence
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    • v.16 no.11
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    • pp.471-476
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    • 2018
  • The purpose of this article is to understand the causes and consequences of the formation and division process of the family relationship and the meaning of the restoration of the family relationship that appeared for the baby-boomer generation, the eco-boomer generation, and the subsequent generation which represent the reality of the time involved. The research method is based on a family that reflects the current age in the drama "My Golden Life" which showed the highest audience rating in the first half of 2018. As a result, the burdens, conflicts, and responsibility of the generations about family relations appeared as unilateral relations. It cut off the entangled relationship and dismantled it. However, the disconnection of the relationship played a role in recovering the subjectivity of the individual from the bridle of the family. As it turned out, the restoration of the family relationship was possible in the bi-directional relationship after the self-esteem and identity of the individual was established first.

Optimal Design of RSOFC System Coupled with Waste Steam Using Ejector for Fuel Recirculation (연료 재순환 이젝터를 이용한 연료전지-폐기물 기반 가역 고체 산화물 연료전지의 최적 설계)

  • GIAP, VAN-TIEN;LEE, YOUNG DUK;KIM, YOUNG SANG;QUACH, THAI QUYEN;AHN, KOOK YOUNG
    • Transactions of the Korean hydrogen and new energy society
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    • v.30 no.4
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    • pp.303-311
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    • 2019
  • Reversible solid oxide fuel cell (RSOFC) has become a prospective device for energy storage and hydrogen production. Many studies have been conducted around the world focusing on system efficiency improvement and realization. The system should have not only high efficiency but also a certain level of simplicity for stable operation. External waste steam utilization was proved to remarkably increase the efficiency at solid oxide electrolysis system. In this study, RSOFC system coupled with waste steam was proposed and optimized in term of simplicity and efficiency. Ejector for fuel recirculation is selected due to its simple design and high stability. Three system configurations using ejector for fuel recirculation were investigated for performance of design condition. In parametric study, the system efficiencies at different current density were analyzed. The system configurations were simulated using validated lumped model in EBSILON(R) program. The system components, balance of plants, were designed to work in both electrolysis and fuel cell modes, and their off-design characteristics were taken into account. The base case calculation shows that, the system with suction pump results in slightly lower efficiency but stack can be operated more stable with same inlet pressure of fuel and air electrode.

The Analysis of Reflect Level according to Reflect Journal in HW Design Learning based on Online Simulation (온라인 시뮬레이션 기반 HW설계 학습에서 성찰일지 내용에 따른 성찰수준 분석)

  • Kim, Jiseon;Ryu, Jiyoung
    • The Journal of Korean Association of Computer Education
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    • v.22 no.5
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    • pp.27-37
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    • 2019
  • In this study, for the purpose of reflection level analysis of high school students in HW design learning which is based on online simulation, we carried out 5 lessons of HW learning and analyzed there reflection levels for 5 individual time of reflection content. The reflection level analysis results for each time of learning shows that the reflection level of the $3^{rd}$ time learning of D-Flip Flop is the highest score with 1.23. The correlation analysis result between the reflection contents presents that high positive correlation between learning content and task resolving method(r=.781, p<.01), and negative design correlation between task resolving method and alternative resolving method. The HW learning satisfaction survey result shows 4.2, and most of the participant students provided opinions that the HW design learning is required and current learning contents is a bit difficult to follow. We could recognize HW design learning is required to have composition of curriculum with basic and advanced contents, and on-off lines combined.

A Study of Critical Items and Related Standards on Designing for Passive Apartments (패시브 공동주택 계획을 위한 설계 중점항목 및 관련 기준 연구)

  • Lee, Myoung-Ju
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.7
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    • pp.21-29
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    • 2018
  • This study aimed to find and suggest the purpose of future plans, critical items on designing and Related standards to amend construction standards for domestic energy saving and environmentally friendly housings. It would also activate and increase the supplies of passive house minimizing the problems on current apartment housings in winter and reducing heating energy which brings fine dust pollution. After defining the standard model of Korean apartment housings(reference model), this study calculated the amount of heating energy demand per unit area annually as applying the yearly changed standards from 2008 to 2017 to existing standard model. It turned out that applying 2017 construction standards of energy saving and eco-friendly housings to reference model has saved up to 75% of heating energy demand comparing to the one applied 2008's. However, it still could not solve the fundamental problems such as winter fungus, condensation, freezing, freeze and burst, and insulation weakness space, and could not be free from fine dust particles. To solve them, this study suggested improved standards adding critical items on design related to outside insulation, cut off the heat-bridge, enforce air-tightness and heat change efficiency on heat recovery ventilator. As a result, it has reduced more than 10% of heat demand from 2017. It would be more than 90% of savings from 2008 if we make the amount of heat loss be zero on heat bridge on designing stage in the future.

A Study on the Improvement Directions for the Industrial Housing Accreditation System in Korea (공업화주택 인정제도 개선 방향 설정에 관한 연구)

  • Hwang, Eun-Kyoung;Lee, Jong-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.1
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    • pp.171-177
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    • 2021
  • The demand for promoting industrialization construction methods is increasing in Korea to cope with various construction environments, such as the lack of construction engineers, aging construction workers, and the government's 52-hour workweek policy. The industrial housing accreditation system was introduced in 1992 to recognize and improve the quality of industrial housing, but only six companies are currently certified, and there are no records of constructing industrial houses. Currently, the industrialized housing accreditation system in Korea comprises standards for the recognition, revocation of recognition, and promoting the construction of industrial houses. Therefore, this study analyzed the regulations of the industrialized housing accreditation system, derived the problems of each regulation, and derived improvement directions to promote the industrialized housing accreditation system in Korea. Specific measures include expanding the current industrial housing accreditation scope to quasi (semi)-housing, revising the performance and production standards of industrialized housing, relaxing the building standards, and providing financial support to promote industrialized housing.

Economic construction management of composite beam using the head stud shear connector with encased cold-formed steel built-up fix beam via efficient computer simulation

  • Yin, Jinzhao;Tong, Huizhi;Gholizadeh, Morteza;Zandi, Yousef;Selmi, Abdellatif;Roco-Videla, Angel;Issakhov, Alibek
    • Advances in concrete construction
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    • v.11 no.5
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    • pp.429-445
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    • 2021
  • With regard to economic efficiency, composite fix beams are widely used to pass longitudinal shear forces across the interface. The current knowledge of the composite beam load-slip activity and shear capability are restricted to data from measurements of push-off. Modelling and analysis of the composite beams based on Euro-code 4 regarding to shear, bending, and deflection under differing loads were carried out using Finite Element through an efficient computer simulation and the final loading and sections capacity based on the failure modes was analysed. In bending, the section potential was increased by an improvement of the strength in both steel and concrete, but the flexural and compressive resistance growth is very weak (3.2% 3.1% and 3.0%), while the strength of the concrete has increased respectively from 25 N/mm2 to 30, 35, and 40 N/mm2 compared to the increment of steel strength by 27% and 21% when it was raised from 275 to 355 and 460 N/mm2, respectively. It was found that the final flexural load capacity of fix beams was declined with increase in the fix beam span for both three steel strength. The shear capacity of sections was remained unchanged at constant steel strength and different length, but raised with final yield strength increment of steel sections by 29%, and 67% when it was raised from 275 N/mm2 to 355 N/mm2 and 460 N/mm2, respectively.

Characteristics of Low Temperature SiNx Films Deposited by Using Highly Diluted Silane in Nitrogen (고희석 SiH4 가스를 이용하여 증착한 저온 PECVD 실리콘 질화물 박막의 기계적, 전기적 특성연구)

  • No, Kil-Sun;Keum, Ki-Su;Hong, Wan-Shick
    • Korean Journal of Metals and Materials
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    • v.50 no.8
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    • pp.613-618
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    • 2012
  • We report on electrical and mechanical properties of silicon nitride ($SiN_x$) films deposited by a plasma enhanced chemical vapor deposition (PECVD) method at $200^{\circ}C$ from $SiH_4$ highly diluted in $N_2$. The films were also prepared from $SiH_4$ diluted in He for comparison. The $N_2$ dilution was also effective in improving adhesion of the $SiN_x$ films, fascilitating construction of thin film transistors (TFTs). Metal-insulator-semiconductor (MIS) and Metal-insulator-Metal (MIM) structures were used for capacitance-voltage (C-V) and current-voltage (I-V) measurements, respectively. The resistivity and breakdown field strength of the $SiN_x$ films from $N_2$-diluted $SiH_4$ were estimated to be $1{\times}10^{13}{\Omega}{\cdot}cm$, 7.4 MV/cm, respectively. The MIS device showed a hysteresis window and a flat band voltage shift of 3 V and 0.5 V, respectively. The TFTs fabricated by using these films showed a field-effect mobility of $0.16cm^2/Vs$, a threshold voltage of 3 V, a subthreshold slope of 1.2 V/dec, and an on/off ratio of > $10^6$.