• Title/Summary/Keyword: obesity status

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Serum Adiponectin but not Leptin at Diagnosis as a Predictor of Breast Cancer Survival

  • Lee, Sang-Ah;Sung, Hyuna;Han, Wonshik;Noh, Dong-Young;Ahn, Sei-Hyun;Kang, Daehee
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6137-6143
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    • 2014
  • Limited numbers of epidemiological studies have examined the relationship between adipokines and breast cancer survival. Preoperative serum levels of obesity-related adipokines (leptin and adiponectin) were here measured in 370 breast cancer patients, recruited from two hospitals in Korea. We examined the association between those adipokines and disease-free survival (DFS). The TNM stage, ER status and histological grade were aslo assessed in relation to breast cancer survival. Elevated adiponectin levels were associated with reduced DFS of breast cancer ($P_{trend}=0.03$) among patients with normal body weight, predominantly in postmenopausal women. There was no association of leptin with breast cancer survival. In conclusion, our study suggests that high levels of adiponectin at diagnosis are associated with breast cancer survival among women with normal body weight.

Clinicopathological Profile of Breast Cancer Patients at a Tertiary Care Hospital in Marathwada Region of Westen India

  • Takalkar, Unmesh Vidyadhar;Asegaonkar, Shilpa Balaji;Kulkarni, Umesh;Kodlikeri, Pushpa R;Kulkarni, Ujwala;Saraf, Mamta;Advani, Suresh
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2195-2198
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    • 2016
  • Background: Breast cancer is the most prevalent malignancy among women with wide differences in clinical profile from region to region. The present study aimed to describe the profile of breast cancer patients attending a tertiary care hospital in Marathwada region of Western India. Materials and Methods: In this descriptive retrospective study, we reviewed records of pathologically diagnosed patients of breast cancer managed at our center from years 2009 to 2015. Data with respect to demographic status, detailed past, medical, familial and personal history, findings of clinical examination and histological features were obtained. Patients were staged according to the Tumor Node Metastasis (TNM) system. Results: Among 260 cases, mean age of presentation was 52.6, with average age of menarche of 11.3 and menopause of 52.6 years. The majority of patients were from urban regions and were postmenopausal (64.3%). Main clinical features presentation were breast lumps. Most patients were in stage II and had infiltrating duct carcinomas. Conclusions: Most common risk factors for breast cancer observed are increasing age, low parity and obesity. Breast cancer was more prevalent among postmenopausal women presenting in stage II with infiltating duct carcinoma in our region of India.

Risk Factors of Breast Cancer (유방암의 위험요인)

  • Chung, Bok-Yae;Byun, Hye-Sun;Kim, Kyung-Duck;Kim, Kyung-Hye
    • Asian Oncology Nursing
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    • v.8 no.2
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    • pp.120-127
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    • 2008
  • Purpose: The purpose of this study was secondary analysis to explore about risk factors with breast cancer on a basis of primary literature. Methods: This study was searched articles by using CINAHL, MEDLINE, Riss4u, Internet website regarding breast cancer. This study searched for the journal published in Korea and foreign countries from 2000 to 2008, about risk factors of breast cancer. This study was reviewed 42 articles (5 experimental study, 35 survey, 1 qualitative study, 1 report) suitable for the research objectives. Results: Magnitude of risk breast cancer (++) was age, geographic region, family history, mutations in BRCA1, BRCA2 genes and in other penetrance genes, radiation, history of benign breast disease, late age of menopause, early age of menarch, nulliparity and older age at first birth, high mammographic breast density, high insulin-like growth factor 1 level. Magnitude of risk factor (+) was hormone replacement therapy, oral contraceptives use, obesity, tall stature, alcohol consumption, high prolactin level, high saturated fat and well-done meat intake, polymorphisms in low penetrance gene, high socioeconomic status. Conclusion: A breast cancer screening protocol according to magnitude of risk factors is needed for disease prevention. The nurses need to educate and counsel women with risk factors of breast cancer.

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The correlation of blood pressure with height and weight in Korean adolescents aged 10-19 years; The Korean National Health and Nutrition Examination Surveys (2009-2011)

  • Song, Young-Hwan
    • Clinical and Experimental Pediatrics
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    • v.57 no.1
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    • pp.35-40
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    • 2014
  • Purpose: Height-specific blood pressure (BP) is the standard parameter used to diagnose childhood hypertension. However, there has been some argument that weight may be a better variable than height in the reference BP standards. Therefore, before assessing the BP status using the reference BP standards, a basic understanding of the fundamental association of weight and height with BP is required. Methods: In the present study, we analyzed the correlation of BP with height and weight in Korean adolescents (age, 10-19 years), using data from the Korean National Health and Nutrition Examination Surveys (2009-2011). Results: Systolic BP (SBP) was more closely correlated with weight than with height in the normal weight (body mass index [BMI], ${\leq}85th$ percentile) and overweight (BMI, >85th percentile) groups and in the normal waist circumference (WC, ${\leq}90th$ percentile) and high WC (>90th percentile) groups in both sexes. Diastolic BP (DBP) had a higher correlation with height than with weight in the normal weight and normal WC groups, whereas weight was more closely associated with DBP than height in the overweight and high WC groups in both boys and girls. Conclusion: In Korean adolescents, weight had a greater effect on SBP than height in both the normal weight and overweight groups. DBP was mainly affected by height in the normal weight group, whereas weight was the major determinant of DBP in the overweight group. Therefore, it may be necessary to consider weight in the establishment of reference BP standards.

A Study on the Anthropometry and Healh-Related Lifestyle Habits of Women College Students in Kunsan (군산시 일부 여대생의 신체적 특성과 식생활 관련습관에 관한 연구)

  • 장혜순;김미라
    • Korean Journal of Community Nutrition
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    • v.8 no.4
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    • pp.526-537
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    • 2003
  • The purpose of this study was to compare the anthropometry and nutrition knowledge, food behaviour and lifestyle of women college students with different obesity indexes. The subjects were 251 women college students who were randomly selected from Kunsan National University. The height, body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were measured, and health-related lifestyle habits were evaluated based on questionnaires. The subjects were assigned to one of the following groups based on their Body Mass Index (BMI) : underweight, normal weight and overweight. The results were as follows. Their body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were significantly higher in the overweight subjects when compared to the underweight or normal weight subjects. Standard of living, self-recognition of health status and duration of exercise were significantly correlated with their BMIs. Self-satisfaction with body weight decreased as the BMI increased. Most subjects had poor habits such as skipping meals and lack of exercises. The overweight and the underweight groups skipped meals more frequently than the normal weight group. There were no significant differences in the scores on the nutritional knowledge and the dietary behaviour of the subjects with different BMIs. Therefore, proper nutritional education on regular meals and intervention are required if women college students are to have normal weights and healthy lifestyles. (Korean J Community Nutrition 8(4) L: 526∼537, 2003)

Health Inequalities in Korea: Current Conditions and Implications (한국 건강불평등의 현황과 문제점)

  • Kim, Yu-Mi;Kim, Myoung-Hee
    • Journal of Preventive Medicine and Public Health
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    • v.40 no.6
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    • pp.431-438
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    • 2007
  • Objectives : The aim of this study is to summarize the current conditions and implications of health inequalities in South Korea. Methods : Through a literature review of empirical studies and supplementary analysis of the data presented in the 1998, 2001, and 2005 KNHANEs, we evaluated the extent and trends of socioeconomic inequalities in both health risk factors, such as smoking, physical activity, and obesity, and outcomes, such as total mortality, subjective poor health status by self-reports and metabolic syndrome. Relative risks and odds ratios were used to measure differences across socioeconomic groups, and the relative index of inequality was used to evaluate the changes in inequalities over time. Results : We found clear inequalities to various degrees?in most health indicators. While little change was observed in mortality differences over time, the socioeconomic gaps in risk factors and morbidity have been widening, with much larger differences among the younger population. Conclusions : Socioeconomic inequalities are pervasive across various health indicators, and some of them are increasing. The trends in socioeconomic inequalities in health should be carefully monitored, and comprehensive measures to alleviate health inequalities are needed, especially for young populations.

A novel nomogram of naïve Bayesian model for prevalence of cardiovascular disease

  • Kang, Eun Jin;Kim, Hyun Ji;Lee, Jea Young
    • Communications for Statistical Applications and Methods
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    • v.25 no.3
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    • pp.297-306
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    • 2018
  • Cardiovascular disease (CVD) is the leading cause of death worldwide and has a high mortality rate after onset; therefore, the CVD management requires the development of treatment plans and the prediction of prevalence rates. In our study, age, income, education level, marriage status, diabetes, and obesity were identified as risk factors for CVD. Using these 6 factors, we proposed a nomogram based on a $na{\ddot{i}}ve$ Bayesian classifier model for CVD. The attributes for each factor were assigned point values between -100 and 100 by Bayes' theorem, and the negative or positive attributes for CVD were represented to the values. Additionally, the prevalence rate can be calculated even in cases with some missing attribute values. A receiver operation characteristic (ROC) curve and calibration plot verified the nomogram. Consequently, when the attribute values for these risk factors are known, the prevalence rate for CVD can be predicted using the proposed nomogram based on a $na{\ddot{i}}ve$ Bayesian classifier model.

Effect Analysis of Healthy City Policies on Residents' Walking (시스템사고로 본 건강도시화 정책이 지역주민의 걷기실천율에 미치는 영향 분석)

  • Kim, Eun-Jung;Kim, Young-Pyo
    • Korean System Dynamics Review
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    • v.13 no.2
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    • pp.25-45
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    • 2012
  • The purpose of this study is to estimate the effects of healthy city policies on residents' walking. In order to estimate promotion of walking rates by healthy cities policies, it developed System dynamics(SD)-based model which showed causal relationships among urban design, public health policies, and walking levels. SD technique is useful for future forecast and policy impact assessment. The spatial units of the SD-based system for policy impact assessment included 66 cities, counties, and communities in Seoul Metropolitan Area. The system simulation was planned to be run for 21 years from 2009 to 2030. For this study, 3 alternatives were proposed with combinations of length of bike lanes, number of bus routes, crime rates, self-reported good health status rates, and obesity rates. As a result of simulations, residents' participation rates for walking were increased from 1.00% to 9.98%. This study contributes to better understanding the benefits of healthy cities that are associated with individual walking. It further provided useful insights into planners' role in promoting health. The paper concluded with a discussion on future research opportunities and implications for public policies in urban and transportation and public health.

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A Study on the Relationship between Fast Food Consumption Patterns and Nutrition Knowledge, Dietary Attitude of Middle and High School Students in Busan (부산 지역 중.고등학생의 패스트푸드 이용 실태와 영양지식, 식생활 태도와의 관련성에 관한 연구)

  • Choi, Min-Kyung
    • Culinary science and hospitality research
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    • v.13 no.2
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    • pp.188-200
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    • 2007
  • This study was carried out to investigate fast food consumption patterns, nutrition knowledge, dietary attitude of middle and high school students in Busan. A questionnaire survey was conducted among 562 students from April 8 to April 22 in 2006. The results are summarized as follows. Convenience to eat is the best motive for visiting fast food restaurants. Nutrition knowledge scores of middle school male students were lower than those of the other groups. The more nutrition knowledge female students have, the lower fast food consumption became. There was no significant difference in nutrition knowledge and fast food consumption in male students. There was a significantly positive correlation between education levels of their parents and dietary attitude of the subjects(p<0.01). Pocket money showed a significantly negative correlation with dietary attitude and with fast food use frequency(p<0.05). There was a significantly positive correlation between nutrition knowledge and dietary attitude of the subjects. The use frequency of fast food showed a negative correlation with dietary attitude(p<0.01) and nutrition knowledge(p<0.05) of the subjects. Therefore, proper nutrition education is required to improve their nutritional status and dietary attitude.

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Influences of Health-related Factors on Uterine Myoma (건강 관련 요인이 자궁근종에 미치는 영향)

  • Choi, Ji-Hyun;Kim, Jeong-Koo
    • The Journal of the Korea Contents Association
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    • v.10 no.1
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    • pp.325-333
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    • 2010
  • Prevalence of female uterine myoma was determined using ultrasound diagnosis instrument, and correlation between health-related factors and uterine myoma was analyzed to investigate concrete factors for production of uterine myoma. Subjects in uterine myoma group and control group were asked to answer the questionnaire survey. The results were determined that prevalence of uterine mayma was 29.7%, and 40~49 aged group showed the highest level of uterine myoma by 41.4%. (p<0.05). The analysis showed that there were significant correlations between uterine myoma and collected variables such as age, marital status, occupational activity level, satisfaction level of life, weight, obesity, delivery history, breast feeding, abortion, and contraceptive experience (p<0.05).