• Nutrition Research and Practice
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• v.13 no.6
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• pp.461-472
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• 2019

BACKGROUND/OBJECTIVES: Globally, it has been projected that there will be 2 billion overweight and 1 billion obese individuals by 2030. In Korea, the prevalence of adult obesity (BMI > 25) increased from 29.7% in 2009 to 32.4% in 2015. Moreover, childhood obesity, which leads to adulthood obesity, has increasingly become a social problem. The purpose of this review is to summarize the scientific basis for the development of effective models and policies aimed at preventing obesity over a lifetime based on research modeling obesogenic environments. MATERIALS/METHODS: The review focuses on the characteristics of obesity prevalence and trends in 3P analysis (papers, patents, and products) as well as government-funded projects in Korean obesity obesogenic environments over the last 10 years. RESULTS AND DISCUSSION: As a result of the 3P analysis, studies on obesity risk factors were frequently carried out, according to two data bases RISS (4.9%) and PubMed (24.7%). Since there were only 17% patents related to the mechanism of preventing obesity in 7,951 Korean patents related to obesity, new paradigms of technologies to dominate the global obesity markets are needed. After government-funded projects were analyzed, communication and cooperation in multi-governmental departments were suggested to elucidate the characteristics of Korean obesity. Government should also produce short- and long-term road maps to develop a practical, successful outcome. Although the rate of obesity in Korea is currently lower than in other developed countries according to WHO criteria, without adequate governmental intervention, obesity rates will approach those of the top countries with high incidence rates of obesity within the next 10 years.

• Journal of Korean Medicine for Obesity Research
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• v.23 no.2
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• pp.98-111
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• 2023

Objectives: The purpose of this study was to review predictive factors associated with weight loss in moderate to severe obesity treatment. The direction of the treatment for moderate to severe obesity will be suggested in consideration of various factors. Methods: Authors searched the articles published from 2018 to 2023 in three international databases (PubMed, Embase and the Cochrane Central Register of Controlled Trials) and two domestic databases (Research Information Sharing Service, Korean studies Information Service System). Studies including treatment with moderate to severe obese patients were selected. Results: A total of 43 studies were included. The main factors of weight loss were unchangeable predictors such as low initial degree of obesity, younger age, non-diabetes and high resting energy expenditure with changeable predictors such as increase in protein, physical activity, self-efficacy, initial weight loss and attendance of the treatment. Conclusions: Our review results suggest that based on the characteristics of moderate to severe obese patients, predictors of weight loss can be used to determine treatment and prognosis in various aspects.

• Journal of Korean Medicine for Obesity Research
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• v.21 no.1
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• pp.42-48
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• 2021

Objectives: The purpose of this study was to review the studies of the wild ginseng complex pharmacopuncture related to obesity treatment. Methods: We searched the papers with key words of 'wild ginseng complex pharmacopuncture', 'wild ginseng pharmacopuncture', 'obesity', 'fat', 'weight' in Oriental medicine Advanced Searching Integrated System, KRpia, Koreanstudies Information Service System, Research Information Sharing Service, KoreaMed and PubMed, Scopus. We classified the papers by year, content and study type. Results: There were 7 studies about the wild ginseng pharmacopuncture related to obesity treatment. Cell studies were excluded because they were not related to obesity. Analysis of 3 animal experiments and 4 clinical studies were conducted to describe each research subject, method, and research results. Conclusion: More interest and further research will be needed on wild ginseng pharmacopuncture related to obesity treatment in the Korean medicine to achieve clinical application and to develop treatment protocols for the obesity disease.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.1
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• pp.77-85
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• 2022

While the Coronavirus disease 2019 (COVID-19) pandemic is gradually turning into an endemic disease, concerns about post COVID-19 conditions (Long COVID) are emerging. Obesity is a major risk factor for severe complications of COVID-19, and COVID-19 has a wide range of effects on obesity and metabolic function. This paper aims to examine the interaction between COVID-19 and obesity, the effects and mechanisms of long COVID on obesity, and the role of Korean medicine on long COVID-related obesity. Obesity may worsen with cardiometabolic damage and psychosocial insecurity during COVID-19 and long COVID-induced neuroinflammation, systemic inflammation, mitochondrial dysfunction, and hypoxia also may aggravate obesity. Korean Medicine treatments, which have been widely used to treat obesity, have the potential to improve obesity in the era of long COVID by intervening in these mechanisms.

• Journal of the Korean Applied Science and Technology
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• v.30 no.4
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• pp.622-634
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• 2013

The multi-origin of obesity and its associated diseases made it's a complex area of biomedical science research and severe health disorder. From the 1970s to onwards this health problem turned to an epidemic without having any report of declining yet and it created a red alert to the health sector. Meanwhile, many animal models have been developed to study the lethal effect of obesity. In consequence, many drugs, therapies and strategies have already been adopted based on the findings of those animal models. However, many complicated things based on molecular and generic mechanism has not been clarified to the date. Thus, it is important to develop a need based animal model for the better understanding and strategic planning to eliminate/avoid the obesity disorder. Therefore, the present review would unveil the pros and cons of presently established animal models for obesity research. In addition, it would indicate the required turning direction for further obesity and obesity based disease research.

• Journal of Korean Medicine for Obesity Research
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• v.14 no.2
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• pp.72-79
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• 2014

The purpose of this study is analyzed of exploratory research potential as anti-obesity agents of Euiiin-tang. Four Korean databases and 2 Korean Journals (Riss4U, KISS, OASIS, DBPIA, and Journal of Korean Rehabilitation Medicine, Journal of Korean Medicine of Obesity Research) were searched using search word 'individual herbs' and 'obesity', 'weight loss', 'fat', 'hypertension', 'hyperlipidemia', 'diabetes'. Clinical and Experimental Research published in the journal were analyzed, review research, studies of pharmacopunctures and studies of mixed herbal medicine were excluded. We collected 23 studies. Seven studies of Coicis Semen, 10 stdies of Ephedra Herba, 2 study of Angelica gigas Nakai, 3 studies Atractylodis Rhizoma Alba, 1 studies of Glycyrrhiza inflata Batal. Most studies were experiment researches which were composed of in vivo or in vitro, and clinical trial was 5 studies of Ephedra Herba. Main constituent herb, Coicis Semen, Ephedra Herba were thought to represent an anti-obesity effect. Through the result, we can assume to be likely effect of Euiiin-tang as obesity medicine.

• Journal of Korean Medicine for Obesity Research
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• v.6 no.1
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• pp.69-80
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• 2006

Object : Waist circumference(WC), waist-hip ratio(WHR), waist-stature ratio(WSR), and body mass index(BMI) are commonly used for evaluating obesity. This Research were done to determine what is more sensitive obesity indexes(WC, WHR, WSR, BMI) Correlated with body composition such as body fat mass, body fat(%), visceral fat area, and fat free mass. And what is more sensitively correlated obesity indexes with % changes of body composition during weight reduction treatment. Methods : This clinical retrospective research were carried out 127 cases of female obese outpatients with weight reduction treatment during 1 month. Bioelectrical impedence analysis(for body composition) and body size(for anthropometric obesity indexes) were estimated in pre-treatment and post-treatment to evaluate the obesity indexes. Pearson correlation coefficients were used to select useful obesity index. Result & Conclusion : BMI is useful index for diagnosis and evaluation of obesity. WSR is sensitively correlated with visceral fat area and body fat(%). So, WSR is useful index for evaluating abdominal obesity and risk factors of metabolic syndrome. WC is correlated with both body fat mass and fat free mass. WHR is not optimal for diagnosis and evaluation of obesity.

• Journal of the Korea Society of Computer and Information
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• v.24 no.1
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• pp.151-158
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• 2019

This study aimed to analyze the research trend related on obesity in physical education in Korea through the keyword network analysis and to establish a basic database for effective design of prospective studies. To achieve it the study crawled co-occured keywords with 'obesity' and 'physical education' from RISS and analyzed the list from 1990 to 2018. They include 25 journal papers and 38 dissertations. The results are as follows. First, recent 30 years 63 papers published in Korea with 'Obesity' and 'Physical Education', and there were 144 related keywords. Second, analyzing journals which have 'Obesity' and 'Physical Education', co-occured keywords in 4 centrality were 24 keywords(student, Korea, prevention, effect, level, body, activation, actual condition, lesson, child, investigation, participation, book, cause, activity, normal, degree, nutrition, physical strength, weight, elementary, light, inquiry, health), and 37 keyword occurred in top 30. Lastly, by CONCOR analysis the result could be divided into 2 clusters. One consists of the object of obesity and its invervention, and the other consists of negative keywords of obesity and its preliminery dimenstion. Through the result, this study showed the research trend which involves the concept of obesity in physical education in Korea. Through the result, prospective obesity research in physical education in Korea would be promoted.

• Biomedical Science Letters
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• v.11 no.2
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• pp.89-101
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• 2005

Obesity is increasing worldwide and has become a major health burden in Western societies affecting every third American and every fifth European. Obesity makes a major contribution to morbidity and mortality, predisposing individuals to cardiovascular disease and diabetes. Many new substances are currently being investigated for their usefulness in the pharmacotherapy of obesity. Most anti-obesity drugs can be divided into four groups: those that reduce food intake; those that alter metabolism; those that increase thermogenesis; and those that regulate hormone involved in feeding behavior. In this article we review these and other agents available in various countries for the treatment of obesity. Perhaps more importantly, we have focussed on areas of potential productivity in the future. Over the last 5 or so years, this impetus in obesity research has provided us with exciting new drugs targets involved in the regulation of feeding behavior and cellular mechanism involved in energy expenditure. Recent development in the quest for control of human obesity include the discovery of hormones, neuropeptides, receptors and transcription factors involved in feeding behavior, metabolic rate and adipocyte development. For developing new, perhaps even more specific pharmacological agents, further research is needed to understand the individual different genetic and physiological basis of obesity. It remains the hope of research scientists that in the not too distant future we shall see a new class of anti-obesity drugs arising logically from the molecular biology revolutions.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.1
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• pp.54-76
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• 2022

Objectives: The purpose of this study is to analyze the research trends of herbal medicine for obesity in animal experiments over the past 5 years. Methods: 5 Databases (Science on, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, PubMed, Cochrane) were searched from 2017 to 2021. Results: A total of 50 studies were selected and analyzed. 21 single herbs and 25 complex formula were used in the studies. The most commonly used herbal material was Poria cocos. As a result, there were significant improvements in the indicators related to obesity or metabolic abnormalities accompanied by obesity in all studies. Conclusions: These results suggest the efficacy and mechanism of herbal medicine for obesity treatment in animal models. Also, there should be more clinical trials in the future, based on this study.