• Title/Summary/Keyword: obesity condition

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Effect of Wild Plant Extracts Based on Korea Traditional Prescription on Endurance Exercise Performance during Calorie Restriction Period (초저열량식이로 인한 체력 저하에서 산야초추출물의 지구력 증진 효과)

  • Kim, Joong-Hark;Kim, Hwa-Young;Chang, Hey-Eun;Chung, Ji-Sang;Hwang, Sung-Joo;Park, Mi-Hyoun;Hong, Seong-Gil
    • Korean Journal of Food Science and Technology
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    • v.38 no.1
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    • pp.147-151
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    • 2006
  • Effects of wild plant extract (Lak) based on Korea traditional prescription on maximal exercise performance and endurance were evaluated using calorie-restriction animal model. In acute forced swimming test with 10% body weight attached to tail, dietary Lak supplementation increased exercise performance endurance by increasing concentrations of ATP and insulin-like growth factor-1 (IGF-1) under calorie-restriction condition, and decrement of blood lactic acid concentration and increment of muscle ATP content were observed. These results suggest Lak is very effective for decreasing side-effects of obesity therapy using very low calorie diet.

Inhibition of Proliferation of LNCaP Prostate Cells by Corni Fructus Extract Is Associated with a Decrease in the Expression of Benign Prostatic Hyperplasia-Causing Factors (산수유 추출물에 의한 LNCaP 전립선 세포의 증식 억제 및 양성 전립선 비대증 유발 인자의 발현에 미치는 영향)

  • Kim, Min Yeong;Ji, Seon Yeong;Hwangbo, Hyun;Lee, Hyesook;Hong, Su Hyun;Choi, Yung Hyun
    • Journal of Korean Medicine for Obesity Research
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    • v.21 no.1
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    • pp.10-21
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    • 2021
  • Objectives: Benign prostatic hyperplasia (BPH) is a progressive pathological condition characterized by excessive proliferation of the prostate. In this study, we evaluated the effect of Corni Fructus water extract (CF) on the promotion of prostate cell proliferation by dihydrotestosterone (DHT). Methods: The effect of CF on the proliferation of LNCaP prostate cells was evaluated, and DHT was treated to induce an in vitro BPH model. To study the mechanism of inhibition of cell proliferation and BPH by CF, changes in the expression of key factors related to cell cycle and BPH were investigated. We further investigated the effect on the production of reactive oxygen species (ROS) and nitric oxide (NO) to evaluate the antioxidant and anti-inflammatory efficacy of CF. Results: Inhibition of LNCaP cell proliferation by CF was associated with decreased expression of cyclin D1 and cyclin A and increased expression of cyclin-dependent kinase inhibitor p21. CF also suppressed expression of BPH inducing factors such as 5α-reductase type 2 and androgen receptor (AR) as well as prostate specific antigen (PSA). Furthermore, CF significantly blocked DHT-induced LNCaP cell proliferation and effectively attenuated DHT-induced expression of BPH mediators and cyclins. In addition, CF inhibited DHT-induced oxidative and inflammatory reactions by inhibiting production of ROS and NO. Conclusion: Our results demonstrated that CF probably acted as 5α-reductase type 2 inhibitor, preventing the 5α-reductase type 2-AR signaling pathway, thereby reducing the conversion of testosterone to DHT and the expression of PSA, which is at least correlated with the antioxidant and anti-inflammatory activities of CF.

Relationship between BCS during Prepartum, Calving and Postpartum Periods and Fertility of Korean Brown Cattle (한우에서 분만 전, 분만 시 및 분만 후의 body condition score와 이후의 번식능력과의 상관관계)

  • Choi, In-Su;Kim, Ui-Hyung;Kang, Hyun-Gu;Kim, Ill-Hwa
    • Journal of Veterinary Clinics
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    • v.25 no.4
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    • pp.280-285
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    • 2008
  • This study evaluated the correlation between the body condition score (BCS) during prepartum, calving and postpartum periods and the reproductive performance of Korean brown cattle. The BCSs of 33 cows who underwent 73 calvings over a two and a half period [the parities of the cows ranged from 1 to 4 ($mean{\pm}SD,\;2.0{\pm}0.9$)] were scored at months 2 and 1 prepartum, calving, and every month postpartum until month 7. A marked prepartum loss of BCS in the month preceding calving was noted. The correlations between the interval from calving to conception and the month 1 prepartum, calving and months 1 and 2 postpartum BCSs were analyzed by Pearson correlation analysis. The correlation between the interval from calving to conception and the prepartum body condition loss was also evaluated. The interval from calving to conception correlated positively with the month 1 prepartum BCS (r = 0.389, P = 0.0007) and the prepartum body condition loss (r = 0.488, P < 0.0001) but did not correlate significantly with the BCS at calving (r=-0.070, P=0.56) or months 1 (r=0.107, P=0.37) or 2 (r=0.102, P=0.39) postpartum. The prepartum body condition loss correlated positively with the month 1 prepartum BCS (r=0.587, P<0.0001). In conclusion, the month 1 prepartum BCS may be a good criterion for predicting subsequent reproductive performance. Moreover, the prevention of obesity and/or excessive prepartum body condition loss may result in higher fertility in Korean brown cattle.

The Analysis of the Real Condition of School Health and the Establishment of a Management System (학교보건(學校保健)의 실태분석(實態分析)과 운영체계(運營體系) 정립(定立))

  • Chang, Kwan-Bong
    • Journal of the Korean Society of School Health
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    • v.6 no.2
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    • pp.24-55
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    • 1993
  • School health aims to guide and manage growing students from elementary schools to high schools in order to grow healthily through the formation of healthy life habits, the self-control health management guide and the making of pleasant school health environments. Even though this school health plays an important role in guiding the students who are in the period of growing to have a perfect personality as a democratic people of our country in the school education, there are many lacks, such as they still don't know the word itself, "school health" or recognize its importance. Also it's a real condition to practice items concerned with the health under the condition of unestablished structure. 1. The results of analyzing school health real conditions. Based on treatises concerned with school health and various statistical materials which are announced by concerned people. We divided and analyzed school health into the items concerned with health education, the items with health management, and the items with school health environments, and investigated the level of the present school health and its necessity. As the items concerned with health education, we investigated the necessary range of school health education, the effect of health education on children's daily life, family's health and the interesting contents of school health. And as the items with health management, I investigated children's obesity, dental caries, eyesight, clinics, a health examination, drug abuse, spirit health, providing meals for school children, and school health manpower. And as the items conerned with school health environments, we investigated the recognition of the problem of natural environments, the management of purification district around the school, the problem of environments within the school and classroom lighting. As the results of analyzing these, I realized that the present level of school health is still in unsatisfactory situation and school health is needed necessary. 2. The establishment of school health. In order to set the school health, above all, the management system of School health should be set. I classified and systemized the contents of each item which had been promoted till now according to the function. They are classified as followings Based on classifying school health into (1) health education, (2) health management and (3) health environments, I divided school health education into the health education of health subjects, the health education of concerned subjects and the education of health life. And I divided health management into the health managements for a prevention and a cure. And I divided health environments into the environment around the school and within the school. Each system set like these is not fixed invariably and I should keep the relationship of mutual supplement between health education and health management, between health management and health environments, and between health environments management and health education. When we run these systemetic school health, students' health could be maintained and improved to more proper directions.

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Effects of a Dye from Artemisia, the Natural Dyeing Material, on the Functionality of Dyeing in Mind-Peace Education for the Silver Generation (실버세대 감성교육을 위한 천연염재 쑥속(Artemisia)식물의 염료가 염색의 기능성에 미치는 영향)

  • Lee, Jung-Eun;Kwon, Young-Suk
    • Journal of Environmental Science International
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    • v.24 no.5
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    • pp.633-639
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    • 2015
  • The experience of natural dyeing is expected to be effective in promoting health through good exercise, in giving emotional stability based on the functional aromatic components of the dyeing material, and in improving self-esteem and increasing positive experiences through the behavior of creation. A natural dyeing material easily found around us, artemisia has long been used in food and Oriental medicine and was recently found to contain antioxidative, anticancer, deodorizing, antibacterial, anti-obesity, and anti-diabetes substances through chemical analysis. It has also been reported that group reminiscence therapy using the fragrance of artemisia is effective in relieving pain and depression and in promoting ego integrity in the elderly population. This study aimed to make a comparative analysis of dyeability, washing fastness, and deodorization between Artemisia princeps, Artemisia iwayomogi, and Artemisia annua, all of which are considered to be healthful and functional dyeing materials, among about thirty domestic plants in the genus of Artemisia and to provide basic data concerning natural dyeing in mind-peace education for the silver generation. The fabric dyed and post-mordanted at $80^{\circ}C$ for 40 minutes showed the greatest surface color variation; in this condition, artemisia princes (32.29) gave the greatest color difference, followed by artemisia iwayomogi (31.07) and artemisia annua (26.17). While all the types of artemisia were excellent in washing fastness, dry-cleaning fastness, and rubbing fastness at the fourth- or fifth-grade, light fastness was at the third grade for artemisia princes, at the second to third grade for artemisia annua, and at the second grade for artemisia iwayomogi; therefore, artemisia princes was found to give better fastness than the other two types of artemisia. In determining functionality of the fabric dyed with artemisia, deodorization test also found that the fabric dyed with artemisia princes had 20% higher deodorization.

Effects of Leoncheon Program on A Student's Physique, Physical Strength, and Constitution (학교급식(學校給食)이 학생(學生)의 체격(體格), 체력(體力) 및 체질(體質)에 미치는 영향(影響))

  • Kam, Byung-Ho;Nam, Chul-Hyun;Shin, Joong-Kyu
    • Journal of the Korean Society of School Health
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    • v.5 no.1
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    • pp.111-119
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    • 1992
  • The study examined the difference of the physique, the physical strength, and the physical constitution between meal and non-meal service schools at the countryside, and concluded as follows: 1) The effects on the physical development Meal service school student's height was 0.41~2.38cm taller, weight 0.21~1.58kg heavier, and the chests 0.15~2.55cm bigger than the non-meal service school students. Therefore, the effects of the school meal service on the student's physique development proved positive. 2) The effects on the physical strength Today, the student's physical growth is reinforced by consuming high calorie food, while their physical exercise is decreased. As a result, obesity becomes another problem. In this respect, physical strength is a significant factor in judging the physical condition of the students. This study compared the meal service schools with the non-meal service schools by suing six items of the physical strength test those schools. In comparison, the meal service school students were better than the others in most items except in the eleven year old girl's 100 meter running and the ball throwing, and the ten year old boy's 600meter running. It means that school meal service affects the physical growth in a positive manner. 3) The effects on the physical constitution The students in their growing period should have their meals not only balanced, but regularly since this helps to maintain their health. Insufficient nutrition may disturb the balanced physical growth of cause a weak or powerless physical constitution. As shown at the table 6, meal service school students who had a balanced meal have 0.01% lower incidence of disease. and 3.11~7.32% less myophia than the other. The average 0.39 to 0.63 cavity of the meal service school students also show that their constitutions are better than the non-meal service ones. In conclusion, the school meal service program gives every student a regular nutritious meal which results in a balanced physical growth. Erentually, the healthier students could be the healthier social menbers which promise a brighter society in the future.

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A Study on the Eating Behavior, Nutrient Intake and Health Condition of College Students Attempting Weight Control in the Daegu Area (체중조절 중인 대구지역 대학생의 식사행동, 영양소 섭취 및 건강상태에 관한 연구)

  • 이영순
    • Journal of the East Asian Society of Dietary Life
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    • v.13 no.6
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    • pp.577-585
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    • 2003
  • The purpose of this study was to investigate eating behavior, nutritional status and health conditions of college students attempting a weight control. The subjects are 88 students of the Daegu area. Their weight, height, triceps, and mid-arm circumference were measured and their dietary intake and eating behavior were obtained by using questionnaires. The 24-hour recall was obtained from the subjects. The results are summarized as follows: The average height, weight and BMI of the attempt and no-attempt male and female students were 171.2cm, 70.7kg and 24.1; 170.4cm, 79.9kg and 27.5; 159.3cm, 60.9kg and 24.0; 157.7cm 60.1kg and 24.2, respectively. Energy intake of the attempt and no-attempt male and female group was 63.9%, 61.8%, 76.2% and 83.9% of RDA respectively. Protein intake of each group was 97.5%, 83.9%, 60.1% and 67.3% of RDA respectively. The following items registered a negative correlation weight and carbohydrate, weight and Na intake, weight and vitamin C intake, PIBW and Na intake, TSF and fiber intake, TSF and Na intake, TSF and vitamin C intake, MAMC and Na intake, and MAMC and vitamin C intake. A relative magnitude of factors affecting weight control was analyzed by Stepwise multiple regression analysis. Overall results about relative influence of independent variables to the dependent variable(weight control) indicated that the BMI (p<0.01) was the most significantly correlated with weight control in all subjects. The results of this study suggest that the extensive nutrition education in the weight control program should be emphasized to prevent obesity early.

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Effect of Yak-Sun Tea Prescription from Oriental Medicinal Herbs for Blood Metabolic Factors of University Women in Jeonbuk Area (한약자원을 이용한 약선차 조성물이 전북 일부지역에 거주하는 여대생의 혈액 성상에 미친 영향)

  • Park Sung-Hye;Song You-Jin;Han Jong-Hyun;Park Sung-Jin
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.2
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    • pp.136-144
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    • 2006
  • This research evaluated how the composition of Yak-sun(oriental diet therapy), taken as a nutritional supplement with daily meals, can effect the medical condition of those suffering from modern diseases like obesity and hyperlipideia. We produced Yak-sun tea, determined its nutrient composition and physical characteristics and evaluated how this tea effects affects the active oxygen concentration inside the body by clinical practices. The study results indicated that this tea significantly decrease active oxygen concentration. We think that scientific and objective evaluation was done on the components of Yak-sun tea prescription. We concluded that we could apply the components not only in the form of tea, but also in other food forms. The information we received from this conclusion will provide basic information for the application of oriental medicinal resources into other foods and will also be a steppingstone in the field of functional food research for the development of medicinal herbs which is already an important research field world-wide.

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Association between Systemic Health Conditions and Self-Reported Oral Health in Korean Elderly (한국노인의 전신건강상태와 주관적 구강건강 관련성)

  • Choi, Eun Sil;Lyu, Jiyoung;Patton, Lauren L.;Kim, Hae-Young
    • Journal of dental hygiene science
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    • v.17 no.1
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    • pp.56-64
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    • 2017
  • Systemic health conditions increase with advancing age, and may be linked to poor self-reported oral health. The purpose of this study was to evaluate the association between systemic health conditions and poor self-reported oral health among Korean elderly. The study used a nationally representative sample of Koreans (2012 Korea National Health and Nutrition Examination Survey) aged 65~98 years (n=1,595). Systemic health conditions in this population were assessed by the presence of one or more of the following conditions: obesity, hypertension, diabetes, and hypercholesterolemia. The relative risk of poor self-reported oral health according to the occurrence of systemic health conditions was estimated by multivariate logistic regression after controlling for several potential confounders (i.e., socio-demographic factors, oral health behaviors, health behaviors, and psychological factors). After adjustment for these confounders, the relative risk of having poor self-reported oral health was greater among the elderly with one or more systemic health conditions than in those without a systemic health condition. The odds ratio of having poor self-reported oral health according to the occurrence of systemic health conditions was 1.51 (95% confidence interval, 1.08~2.12). Among the Korean elderly, perception of poor oral health was associated with the presence of one or more systemic health conditions. Future studies are needed to examine the detailed causal relation between systemic health conditions and poor oral health longitudinally.

Anti-apoptotic effect of fermented Citrus sunki peel extract on chemical hypoxia-induced neuronal injury (화학적 저산소증이 유도하는 뇌신경세포 손상에 있어서 미성숙 진귤 과피 발효 추출물의 보호 효과)

  • Ko, Woon Chul;Lee, Sun Ryung
    • Journal of Nutrition and Health
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    • v.48 no.5
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    • pp.451-456
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    • 2015
  • Purpose: Neuronal apoptotic events induced by aging and hypoxic/ischemic conditions is an important risk factor in neurodegenerative diseases such as ischemia stroke and Alzheimer's disease. The peel of Citrus sunki Hort. ex Tanaka has long been used as a traditional medicine, based on multiple biological activities including anti-oxidant, anti-inflammation, and anti-obesity. In the current study, we examined the actions of fermented C. sunki peel extract against cobalt chloride ($CoCl_2$)-mediated hypoxic death in human neuroblastoma SH-SY5Y cells. Methods: Cell viability was measured by trypan blue exclusion. Expression of apoptosis related proteins and release of cytochrome c were detected by western blot. Production of intracellular reactive oxygen species (ROS) and apoptotic morphology were examined using 2',7'-dichlorofluorescin diacetate (DCF-DA) and 4',6-diamidino-2-phenylindole (DAPI) staining. Results: Exposure to $CoCl_2$, a well-known mimetic agent of hypoxic/ischemic condition, resulted in neuronal cell death via caspase-3 dependent pathway. Extract of fermented C. sunki peel significantly rescued the $CoCl_2$-induced neuronal toxicity with the cell viability and appearance of apoptotic morphology. Cytoprotection with fermented C. sunki peel extract was associated with a decrease in activities of caspase-3 and cleavage of poly (ADP ribose) polymerase (PARP). In addition, increase in the intracellular ROS and release of cytochrome c from mitochondria to the cytosol were inhibited by treatment with extract of fermented C. sunki peel. Conclusion: Based on these data, fermented C. sunki peel extract might have a protective effect against $CoCl_2$-induced neuronal injury partly through generation of ROS and effectors involved in mitochondrial mediated apoptosis.