• The Journal of Korean Medicine
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• v.29 no.2
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• pp.116-132
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• 2008

Objective: This study investigated the effects of Bimanbang-1 (肥滿1號方: here in after referred to BMB-1) on the obese gene and obese inhibitory. Methods: C57BL/6 mice were induced by high fat diet. Mice were divided into three groups (normal, high fat diet with control, high fat diet with BMB-1 extract) and fed for 15 weeks. Items of this experimental study are as follows: body weight change, final body weight, the weight change of the adipocytes in body, the level change of LFT, NEFA and creatinine, the expression of ${\beta}3AR$ and leptin gene in primary adipocytes, the production change of leptin in primary adipocytes, the expression of ${\beta}3AR$, leptin and $TNF-{\alpha}$ in adipocytes tissue. Result: 1. All experimental groups showedthat the weight change decreased considerably and the high density group showedthat the final weight decreased considerably. 2. The high density group showed that the amount of the adipocyte in weight decreased considerably. 3. All experimental groups showedthat the amount of ALT decreased considerably, and AST decreased in the high density group. However, the amount of creatinine and glucose did not increase considerably. 4. All experimental groups showed that the amount of total cholesterol, LDL-cholesterol, triglyceride, and NEFA decreased, and HDL-cholesterol increased considerably. 5. The high density groups showedthat the amount of leptin decreased considerably. 6. All experimental groups showed that the revelation of ${\beta}3AR$ in primary adipose cell and 3T3-L1 cell increased considerably, and that the revelation of leptin and $TNF-{\alpha}$ in primary adipose cellsand 3T3-L1 cells decreased considerably. 7. All experimental groups showed that the size of adipocyte in adipocytes tissue decreased. 8. All experimental groups showed that the adipose vacuoles in liver tissue decreased considerably. Conclusion: The findings suggest that Bimanbang-1 causes weight loss and histological change, thus it may be effective to treat obesity.

• Korean Journal of Adult Nursing
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• v.28 no.6
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• pp.701-708
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• 2016

Purpose: This study investigated Korean women in between age 30 to 60 who were obese or overweight in order to explore their self-perception based on lifetime phase. Methods: Focus group interviews were performed four times with six to eight participants in each group (a total of 27). Data were analyzed using inductive thematic analysis. Results: The data analysis from the interviews revealed recurring common themes: heavy heart, heavy body, resigned acceptance of their own condition, and compromise. The study also found that each age group had different concerns: concerning others' gaze on their obese appearances (30s), realizing their aging obese appearances (40s), recognizing red flags of their health with obesity (50s), and becoming ambivalent about their obese appearances (60s). Overall, their perceptions of being overweight were negative and stressful. Women in their 30s and 40s were more interested in their appearances, and thus were more obsessive about weight gain. In contrast, women in their 50s and 60s were more accepting of their physical appearances, and thus were more concerned about living healthy than losing weight. Conclusion: These results may be useful to consider when developing tailored weight-control programs for obese and overweight Korean women. Additionally, strategic approaches for successful and effective programs targeting healthy weight should be based on better understanding about women's self-perceptions and motivations.

• Korean Journal of Community Nutrition
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• v.7 no.4
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• pp.506-515
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• 2002

This study examined the state of health and weight maintenance according to the body mass index (BMI) , and explored demographic variables, diet variables, the degree of stress etc. The results presented were based on data collected from 428 women who are mothers of the middle school children in Jeongeup city. Using SPSS WIN (Ver 9.0) , the frequency, percentage, mean, standard deviation, chi-square, ANOVA, and correlation analysis were provided. The mean of BMI for the subjects was 22.6, the ratio of obese women (BMI $\geq$ 25) was 22.9%. The frequency of the reported circulation or respiratory related diseases was greater in the obese group compared to the normal weight ($20 \leq BMI \leq 25$) or the lean (BMI < 20) groups. The obese group had less awareness of obesity. Those who regard themselves obese had lower rates of satisfaction with their body shape and higher rates of interest in weight control. Approximately 65% of the subjects attempted weight reduction more than once. Subjects who were obese had the most undesirable dietary behavior. In particular, this group had the higher rates of rushed meals, overeating, meals while watching TV or newspapers, and snacking, and eating out. In analyzing the correlation of variables influencing obesity, there were positive correlations between obesity and overeating, obesity and the degree of stress. Correlations between obesity and satisfaction for life found to be negative. Moreover, stress had a positive correlation with obesity and overeating, and showed negative correlation with eating behavior. Consequently, stress seemed to induce undesirable eating behaviors and increase obesity. Of the demographic background variables, subjects who were obese tended to be older, had lower levels of education, higher rates of employment, longer period of marriage, the higher number of children, preschool children or children preparing for highschool or college, lower satisfaction with children and household life.

• Korean Journal of Community Nutrition
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• v.11 no.6
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• pp.683-694
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• 2006

The purpose of this study was to determine the body weight control, food habits and nutrient intakes according to the obese index in male middle school students. This study was carried out through questionnaires and measurement by body fat analyzer (Inbody 4.0). The subjects were 275 male middle school students in Iksan. Chonbuk province. The average age, height, weight, and BMI of the subjects were 14.4 years old, 167.8 cm, 60.2 kg and $21.3kg/m^2$, respectively. Seventeen point one percent of the subjects were the underweight group, 47.6% were the normalweight group, and 35.3% were the overweight group by the classification of the Korean Pediatrics Society standard. Body fat of underweight, normalweight, and overweight were 16.1%, 19.0%, and 26.6%, respectively. Thirty one point nine percent of underweight, 39.7% of normalweight. and 31.9% of overweight had misperceptions of their weight (p<0.001). Sixty two point two percent of the males were dissatisfied with their body weight, and 55.3% of the whole tried to reduce their body weights. Even though they were normalweight, half of them dissatisfied with their weight. The source of weight control method was friends and family, TV radio, Internet, and school nutrition education, in order. The subjects exercised 3.4 days per week, 70.2 minutes per day, but it was not different significantly by the obese index. Forty percent of the subjects had meals fast, 58.5% of them have biased food habits even if they didn't differ by the obese index. Activity rate was different by the obese index significantly (p < 0.05), the number of severe activity was most in underweight. In conclusion, nutrition education programs should contain the necessity of normalweight, and regularity of lift habits and activities for energy expenditure in overweight students. It made them to recognize their weight correctly, establish healthy body images, and raise the ability to promote health and improve nutritional status.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.2
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• pp.22-31
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• 2019

Objective This study is to learn the effects of Hataedock method using Coptidis rhizoma and Glycyrrhiza uralensis mixed extract on inflammatory response in allergic rhinitis-induced obese NC/Nga mice. Materials and Methods The mice were fed with high fat-diet to be obese, and were divided into 3 groups as follows; allergic rhinitis-induced obese mice group with Hataedock method (CGT, n=10), no treatment group (Ctrl), allergic rhinitis elicited obese mice group (ARE). To induce allergic rhinitis, NC/Nga mice of 3 weeks age were sensitized on 7, 8 and 9 weeks by ovalbumin antigen in intraperitoneal space. After 7 days of final sensitization, allergic rhinitis was initially induced in mice through nasal cavities for 5 days. After 1-week, allergic rhinitis was induced again by the same method. Histological examination was used to identify distribution of IL-4, CD40, STAT6, $Fc{\varepsilon}RI$, substance P, MMP-9, NF-${\kappa}B$ p65, iNOS and COX-2. Results Hataedock method significantly reduced IL-4, STAT6 and CD40 response (p<0.05). In CGT, the inhibition of Th2 differentiation decreased inflammatory mediators such as $Fc{\varepsilon}RI$, substance P, MMP-9, NF-${\kappa}B$ p65, iNOS and COX-2 (all p<0.05). The immunological improvement led reduction of respiratory epithelial damage and mucin secretion in goblet cell. Conclusion The results of this study show that the Hataedock method suppresses the expression of allergic rhinitis by decreasing the inflammatory mediators through the regulation of Th2 differentiation even when the inflammation reaction is increased by obesity. Therefore, Hataedock may have potential preventive measure of allergic rhinitis accompanied by obese.

• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.3
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• pp.516-520
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• 2001

This study was conducted to investigate whether the obesity of obese fa/fa male Zucker rats can be ameliorated by mulberry leaves. There was no significant difference between mulberry treatment group and control group in body weight gain and food efficiency ratio. It also showed decreases on plasma triglyceride and total-cholesterol concentration compared to the control group. But there was no change in plasma leptin concentration between the control and mulberry treatment groups. These results suggest that mulberry leaves reduce serum lipid levels, but do not effect the plasma leptin concentration.

• Journal of the Korean Society of Clothing and Textiles
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• v.24 no.2
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• pp.192-198
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• 2000

This study was conducted in autumn and winter to investigate the wearing habit of the obese children in the cold. Eighty elementary school children were volunteered as the subjects. Forty of them were selected as the obesity group(OG) and the other forty children were selected as the normal body weight group(NG). Clothing weight and motor ability of the subjects were measured and correlation of the clothing weight between the children and their mothers were investigated. Clothing weight did not show significant difference between OG and NG in autumn but in winter. In winter, boys' lower clothing weight was less while girls' upper clothing weight was less in OG than in NG. Motor ability was better in NG than OG but no correlation was found between clothing weight and motor ability in both group except for upper clothing weight in NG. There was no correlation of total clothing weight between girls and their mothers but between boys and their mothers.

• Korean Journal of Human Ecology
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• v.18 no.6
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• pp.1337-1348
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• 2009

This study was conducted to determine major factors underweight and obesity by comparing and analyzing dietary habits, exercise and weight control of obesity and underweight of Adolescents. The subjects were 26,039 students and they were divided according Body Mass Index(BMI). The collected data was analyzed through frequency, percentage, chi-square test. The results were as follows. 1) Among the male students 67.3%, 32.7% and among the female ones 82.7% and 17.3% were included in the underweight and the obese groups, respectively. 2) For dietary habits, the rate of skipping breakfast(12.5%, 13.6%) was considerably higher than those of skipping lunch and dinner. 3) The females and the obese group received more stress, felt more unhappiness, grief, depression and thought more suicide than the males and the underweight group, respectively. 4) The underweight group had higher rate of strengthening exercise of males and females. 5) For self-recognized body shape, while in the underweight group had a wrong image of their body shape, while more males in the obese group had a distorted self body image. 6) Measures to control weight were regular exercise, reduced amount of diet, and the obese group controled their weight more actively than the underweight group of the male and the female students. 7) From these results, appropriate mental health programs and education programs about health knowledge, properly self-recognized body shape and measures to control weight were considered to be necessary.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.3
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• pp.634-641
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• 2007

In order to investigate the effects of Bogigambi-tang(here in after referred to BGGBT) on the obese gene and obese inhibitory, C57BL/6 mice were induced by high fat diet. C57BL/6 mice were divided into three groups(normal, high fat diet with control, high fat diet with BGGBT extract) and fed for 15 weeks. Items of this experimental study are as follows. Body weight change, final inclose of body weight, the weight change of the adipocytes in body, the level change of ALT, AST, total cholesterol, LDL-Cholesterol, triglyceride, glucose, free fatty acid and creatinine, the expression of ${\beta}$3AR and leptin gene in primary adipocytes, the production change of leptin in primary adipocytes, the expression of ${\beta}$3AR and leptin in adipocytes tissue. The following results have been obtained All experimental group have shown that the weight and the final increase of weight have decreased considerably. All experimental group have shown that the amount of the adipocyte in weight has decreased considerably. All experimental group have shown that the amount of leptin has decreased considerably. All experimental group have shown that the revelation of ${\beta}$3AR in primary adipose cell and 3T3-L1 cell has increased considerably, and that the revelation of leptin in primary adipose cell and 3T3-L1 cell has decreased considerably, All experimental group have shown that the size of adipocyte in adipocytes tissue has decreased. The high density group have shown that the adipose vacuoles in liver tissue has decreased considerably, and that the cell nucleuses has similar with normal group.

• Journal of The Korean Society of Integrative Medicine
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• v.6 no.1
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• pp.35-44
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• 2018

Purpose : The purpose of this study is to comparison of the effects of proprioception traning and muscle strength traning on the ankle strength and balance of obese middle-aged woman. Method : The subjects of this study are obese-middle aged woman; 8 woman who agreed with this research, were picked up. Participants were divided randomly into equal groups: experimental group receved proprioception traning for 6 weeks, which consists of 3 times per week, 30 min for each session. control group received strength training during the same period. Muscle strength and balance were measured dorsi flexion, plantar flexion, functional reach test and one leg standing. The intervention were compared by measuring before and after. Result : There were significant improvements in the subscales of the muscle strength of both group and balance test of those who practiced with the proprioception traning, while the muscle strength traning showed significant changes only muscle strength. Conclusion : Therefore, proprioception training is beneficial in improvement of to improve the muscle strength and balance in middle-aged woman with obesity.