• 전기전자학회논문지
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• 제19권3호
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• pp.447-454
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• 2015

본 논문은 ISO/IEEE 11073 개인건강기기 표준에서 정의된 PM-store 개념을 적용하여 주기적으로 발생하는 대용량 측정 데이터의 전송 프로토콜을 구현할 경우, 개인건강기기의 중앙처리장치(CPU)에서 수행해야 하는 명령사이클(instruction cycles)의 수를 기반으로 한 복잡도 분석에 대한 연구이다. PM-store의 구성에 따라 중앙처리 장치가 처리해야 할 명령 사이클의 수에 대한 분석모델을 제시하였다.

• 한국도로학회논문집
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• 제16권6호
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• pp.115-120
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• 2014

PURPOSES : This research describes how to predict the life cycles of fatigue cracking based on NCHRP Report 704 as well as modified harmony search (MHS) algorithm. METHODS : The fatigue cracking regression model of NCHRP Report 704 was used in order to calculate the ESAL (Equivalent Single Axle Load) numbers up to pavement failure, based on using material parameters, composite modulus, and surface pavement thickness. Furthermore, the MHS algorithm was implemented to find appropriate material parameters and other structural conditions given the number of ESALs, which is related to pavement service life. RESULTS : The case studies show that the material and structural parameters can be obtained, resulting in satisfying the failure endurance of asphalt concrete structure, given the number of ESALs. For example, the required ESALs such as one or two millions are targeted to satisfy the service performance of asphalt concrete pavements in this study. CONCLUSIONS : According to the case studies, It can be concluded that the MHS algorithm provides a good tool of optimization problems in terms of minimizing the difference between the required service cycles, which is a given value, and the calculated service cycles, which is obtained from the fatigue cracking regression model.

• 한국지능시스템학회논문지
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• 제16권4호
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• pp.396-401
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• 2006

순환결합형 신경회로망은 복수 개의 리미트사이클을 생성하며 따라서, 많은 동적 정보를 저장할 수 있는 메모리 시스템으로 사용할 수 있다는 것이 알려져 있다. 본 논문에서는 각 뉴런이 최근접 뉴런에만 이진화한 결합하중 ${\pm}1$로 연결된 연속 시간모델 순환결합형 신경회로망을 구현하였다. 그리고 이런 회로망을 통해 생성되는 리미트사이클의 수와 패턴을 시뮬레이션을 통하여 나타내었다. 또한 카오스 신호를 인가하여 리미트사이클 사이의 천이 가능성을 입증하였다. 특히, 카오스 신호 이외의 랜덤 노이즈를 이용한 해석을 통하여 동적 신경회로망에 카오스 노이즈를 인가하는 경우의 유효성을 검토하였다.

• Journal of information and communication convergence engineering
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• 제6권3호
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• pp.285-288
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• 2008

Most of multimedia processors for 2D/3D graphics acceleration use a lot of integer/floating point arithmetic units. We present a new architecture with an efficient ALU, built in a smaller chip size. It reduces instruction cycles significantly based on a foundation of multi-thread operation, variable length instruction words, dual phase operation, and phase instruction's coordination. We can decrease the number of instruction cycles up to 50%, and can achieve twice better performance.

• Clinical and Experimental Reproductive Medicine
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• 제47권4호
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• pp.300-305
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• 2020

Objective: The feasibility of a gonadotropin-releasing hormone agonist (GnRHa) trigger in normal responders is still a matter of debate. The aim of this study was to compare the number of mature oocytes, the number of good-quality embryos, and the live birth rate in normal responders triggered by GnRHa alone, GnRHa and human chorionic gonadotropin (hCG; a dual trigger), and hCG alone. Methods: A retrospective cohort study was conducted at the infertility clinic of a university hospital. Data from 200 normal responders who underwent controlled ovarian hyperstimulation and intracytoplasmic sperm injection with a GnRH antagonist protocol between January 2016 and January 2017 were reviewed. The first study group consisted of patients with cycles triggered by GnRHa alone. The second study group consisted of patients with cycles triggered by both GnRHa and low-dose hCG (a dual trigger). The control group consisted of patients with cycles triggered by hCG alone. Results: The groups were comparable in terms of demographics and cycle characteristics. The numbers of total oocytes retrieved and metaphase II oocytes were similar between the groups. The total numbers of top-quality embryos were 3.2±2.9 in the GnRHa group, 4.4±3.2 in the dual-trigger group, and 2.9±2.1 in the hCG group (p=0.014). The live birth rates were 21.4%, 30.5%, and 28.2% in those groups, respectively (p=0.126). Conclusion: In normal responders, a dual-trigger approach appears superior to an hCG trigger alone with regard to the number of top-quality embryos produced. However, no clinical benefit was apparent in terms of live birth rates.

• Clinical and Experimental Reproductive Medicine
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• 제13권1호
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• pp.67-75
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• 1986

Follicle monitoring in the normal and clomiphene·stimulated cycles were analyzed in the Seoul IVF and ET (In vitro fertilization and embryo transfer) program. Ovarian follicular diameters were measured by the real·time sector scanner and plasma estradiol levels were assayed by radioimmunoassay methods during periovulatory period. The maximum follicular sizes of the clomiphene-stimulated and normal cycles were 21.1+-3.4mm and 19.2+-0.8mm, respectively. The peak levels of plasma estradiol in the clomiphene-stimulated and normal cycles were 10538+-553.6ng/ml and 298.3+-39.6pg/ml, respectively. Daily growth rate of the follicular diameters of the clomiphene-stimulated and normal cycles were 2.1mm and 1.9mm, respectively. Mean follicular number of the clomiphene-simulated and normal cycles were 2.28+-1.12 and 1.12+-0.21, respectively. There was a good statistical correlation between the mean follicular diameters and the plasma estradiol levels in the normal ovulatory and c1omiphene-stimulated ovulatory menstrual cycles (p<0.05). Our data revealad that the mean follicular diameter and the plasma estradiol level prior to HCG administration in IVF and program should reach at the level of 17.8+-3.0mm and 949.4+-487.1 pg/ml, respectively.

• Clinical and Experimental Reproductive Medicine
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• 제38권4호
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• pp.234-237
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• 2011

Objective: During stimulated IVF cycles, up to 15% of oocytes are recovered as immature. The purpose of this study was to investigate the trend of oocyte maturity in repeated ovarian stimulation for IVF. Methods: One hundred forty-eight patients were selected who underwent two consecutive IVF cycles using same stimulation protocol during 2008 to 2010. Ovarian stimulation was performed with FSH and human menopausal gonadotropin and flexible GnRH antagonist protocol in both cycles. Oocyte maturity was assessed according to presence of germinal vesicle (GV) and the first polar body. Immature oocyte was defined as GV stage or metaphase I oocyte (GV breakdown with no visible polar body) and cultured up to 48 hours. If matured, they were fertilized with ICSI. Results: Percentages of immature oocytes were 30.8% and 32.9% ($p$=0.466) and IVM rates of immature oocytes were 36.2% and 25.7% ($p$=0.077), respectively. A significant correlation was noted between percentage of immature oocytes in the two cycles (R=0.178, $p$=0.03). Women with >40% immaturity in both cycles (n=21) showed lower fertilization rate of $in$ $vivo$ matured oocytes (56.4% vs. 72.0%, $p$=0.005) and lower pregnancy rate (19.0% vs. 27.1%, $p$=0.454) after the second cycle when compared with women with <40% immaturity (n=70). In both groups, female age, number of total retrieved oocyte and embryos transferred were similar. Conclusion: In repeated ovarian stimulation cycles for IVF, the immature oocyte tended to be retrieved repetitively in consecutive IVF cycles.

• 융합신호처리학회논문지
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• 제12권4호
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• pp.355-361
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• 2011

기존 발열체의 전력제어는 On-Off 제어, 위상제어, PWM 제어를 사용해왔다. 최근 개발된 PTC 발열체를 기존의 방법으로 전력제어를 하였을 경우, 온도를 정밀하게 제어하지 못하고 인체에 유해한 전자파가 발생한다. 본 논문은 AC Cycles 가변을 이용한 PTC 열선의 전력 제어를 제안한다. 이것은 N개의 교류 cycle을 전력 제어의 단위로 간주하여, 각 cycle 마다 On-Off 여부를 결정하여 N cycles 내의 on-cycle 을 랜덤하게 배치하여 지속적으로 AC전력제어방법이다. 이 때 최소 전력량은 1/N이 되고 최대 전력량은 1이 되며 설정 값에 따라 on cycle의 수를 설정하여 N개의 단계로 일정하게 전력을 제어할 수 있다. PTC 열선과 온도센서를 사용한 발열 시스템에서 제안한 전력제어 방식이 전자파 발생과 온도제어 특성에서 우수함을 MATLAB simulation과 실험 및 측정을 통하여 확인하였다.

• Clinical and Experimental Reproductive Medicine
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• 제41권4호
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• pp.158-164
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• 2014

Objective: To assess whether an early GnRH antagonist start leads to better follicular synchronization and an improved clinical pregnancy rate (CPR). Methods: A retrospective cohort study. A total of 218 infertile women who underwent IVF between January 2011 and February 2013. The initial cohort (Cohort I) that underwent IVF between January 2011 and March 2012 included a total of 68 attempted IVF cycles. Thirty-four cycles were treated with the conventional GnRH antagonist protocol, and 34 cycles with an early GnRH antagonist start protocol. The second cohort (Cohort II) that underwent IVF between June 2012 and February 2013 included a total of 150 embryo-transfer (ET) cycles. Forty-three cycles were treated with the conventional GnRH antagonist protocol, 34 cycles with the modified early GnRH antagonist start protocol using highly purified human menopause gonadotropin and an addition of GnRH agonist to the luteal phase support, and 73 cycles with the GnRH agonist long protocol. Results: The analysis of Cohort I showed that the number of mature oocytes retrieved was significantly higher in the early GnRH antagonist start cycles than in the conventional antagonist cycles (11.9 vs. 8.2, p=0.04). The analysis of Cohort II revealed higher but non-significant CPR/ET in the modified early GnRH antagonist start cycles (41.2%) than in the conventional antagonist cycles (30.2%), which was comparable to that of the GnRH agonist long protocol cycles (39.7%). Conclusion: The modified early antagonist start protocol may improve the mature oocyte yield, possibly via enhanced follicular synchronization, while resulting in superior CPR as compared to the conventional antagonist protocol, which needs to be studied further in prospective randomized controlled trials.

• Clinical and Experimental Reproductive Medicine
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• 제44권2호
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• pp.96-104
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• 2017

Objective: This study aimed to compare the clinical outcomes between in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in sibling oocytes. Additionally, we evaluated whether the implementation of split insemination contributed to an increase in the number of ICSI procedures. Methods: A total of 571 cycles in 555 couples undergoing split insemination cycles were included in this study. Among them, 512 cycles (89.7%) were a couple's first IVF cycle. The patients were under 40 years of age and at least 10 oocytes were retrieved in all cycles. Sibling oocytes were randomly allocated to IVF or ICSI. Results: Total fertilization failure was significantly more common in IVF cycles than in ICSI cycles (4.0% vs. 1.4%, p<0.05), but the low fertilization rate among retrieved oocytes (as defined by fertilization rates greater than 0% but < 30%) was significantly higher in ICSI cycles than in IVF cycles (17.2% vs. 11.4%, p<0.05). The fertilization rate of ICSI among injected oocytes was significantly higher than for IVF ($72.3%{\pm}24.3%$ vs. $59.2%{\pm}25.9%$, p<0.001), but the fertilization rate among retrieved oocytes was significantly higher in IVF than in ICSI ($59.2%{\pm}25.9%$ vs. $52.1%{\pm}22.5%$, p<0.001). Embryo quality before embryo transfer was not different between IVF and ICSI. Although the sperm parameters were not different between the first cycle and the second cycle, split insemination or ICSI was performed in 18 of the 95 cycles in which a second IVF cycle was performed. Conclusion: The clinical outcomes did not differ between IVF and ICSI in split insemination cycles. Split insemination can decrease the risk of total fertilization failure. However, unnecessary ICSI is carried out in most split insemination cycles and the use of split insemination might make ICSI more common.