• 제목/요약/키워드: nuclear problem

검색결과 788건 처리시간 0.027초

지식기반 반응 시 인간과오 관련 뇌파 밴드파워의 변화 (Variation of EEG Band Powers Related with Human Errors in Knowledge-based Responses)

  • 임현교;김홍영
    • 한국안전학회지
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    • 제28권3호
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    • pp.107-113
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    • 2013
  • Problem solving and/or decision making process usually encountered in human living consists of a sequence of human behaviors based upon his/her knowledge. Thus, Rasmussen introduced Skill-Rule-Knowledge paradigm to countermeasure human errors that can occur in Nuclear Power Plants. Unfortunately however, it was not so easy as expected since objective evidence have not been obtainable with conventional research techniques. With the help of EEG band pawer ratio techniques, this study tried to get psycho-physiological symptoms of human errors, if any, while human beings perform knowledge-based behaviors such as simple arithmetic computations with different difficulty level. A set of simulated works was carried out with a computer station. Four kinds of arithmetic computation tasks were given to 10 health male under-graduate students on different day individually, and during the experiment, EEG and ECG was measured continuously for objective psycho-physiological analysis. According to the results, ${\alpha}$/(${\alpha}+{\beta}$) as well as ${\alpha}/{\beta}$ band power ratio were sensitive to task difficulty level which consistently decreased both. However, any one of them failed to reveal the influence of tasks with different difficulty level in the aspect of task duration time. On the contrary, Heart Rate Variability was more suggestive than expected. To make a conclusion, it can be said that band power of EEG waves will be helpful in not only assessment of work difficulty level but also assessment of workers' skill development if supported by cardiac function such as HRV.

선체냉각을 위한 해수분사노즐의 산포특성에 관한 실험 연구 (An Experimental Study on the Dispersion Characteristics of Seawater Injection Nozzle for Hull Cooling)

  • 윤석태;정호석;조용진
    • 한국군사과학기술학회지
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    • 제20권6호
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    • pp.767-773
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    • 2017
  • Infrared stealth is an important technology for naval ships. This technology helps improve the anti-detection performance and survivability of naval ships. In general, the infrared signature of naval ships are categorized into internal and external heat source. External signature are generated by ship surface heating by solar flux as well as the complicated heat transfer process with the surrounding weather condition. Modern naval ships are equipped with seawater injection nozzles on the outside for nuclear, biological and, chemical, and these nozzles are used to control external signature. Wide nozzle placement intervals and insufficient injection pressure, however, have reduced seawater dispersion area. To address this problem, nozzle installation standards must be established. In this study, an actual-scale experimental system was implemented to provide the evidence for nozzle installation standards in order to reduce the infrared signature of naval ships. In addition, the environmental conditions of the experiment were set up through computational fluid dynamics considering the ocean climate data and naval ship management conditions of South Korea. The dispersion distance was measured using a high-resolution thermography system. The flow rate, pipe pressure, and dispersion distance were analyzed, and the evidence for the installation of seawater injection nozzles and operation performance standards was suggested.

슈반세포종 23예의 세침흡인 세포검사에 대한 세포소견 (Cytologic Findings of Fine Needle Aspiration Biopsy of 23 Schwannomas)

  • 장선희;주미;김한성
    • 대한세포병리학회지
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    • 제19권1호
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    • pp.41-46
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    • 2008
  • In an attempt to better define the cytologic characteristics of schwannomas, we have reviewed aspirates and corresponding histologic sections from 23 schwannomas. Of this number, the original cytologic diagnoses were: schwannoma in 14 cases (61%), benign soft tissue tumor in 2 cases (9%), and insufficient specimen in 7 cases (30%). The cytologic findings common to all cases of schwannoma included fragments of tightly cohesive fascicles with variable cellularity and corresponding Antoni type A area. The Antoni type B area, consisting of scattered spindle cells and some histiocytes and lymphocytes against a myxoid background, was seen in 14 cases. Fibrillary stroma was seen in 12 cases. The tumor cells had spindle- or ovalshaped nuclei, with pointed ends and indistinct cell borders. Nuclear palisading was seen in 10 cases, and distinctive Verocay bodies were seen in 5 cases. In ancient schwannomas, there were no Verocay bodies. Most schwannomas have distinct cytomorphologic features that allow correct diagnosis. The major problem with fine needle aspiration cytology of these tumors is the high frequency of poor cellularity, particularly in lesions with cystic degeneration. Of 7 cases with insufficient specimen, 4 showed marked cystic changes and 1 showed marked hyaline changes on histologic sections. In conclusion, we believe that if cytopathologist reminds the situation such as cystic degeneration or hyaline degeneration, the correct diagnosis of the schwannoma will be easily made.

Factors Associated with Vancomycin-Resistant Enterococcus Colonization in Patients Transferred to Emergency Departments in Korea

  • Kim, Hyun Soon;Kim, Dae Hee;Yoon, Hai-jeon;Lee, Woon Jeong;Woo, Seon Hee;Choi, Seung Pill
    • Journal of Korean Medical Science
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    • 제33권48호
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    • pp.295.1-295.7
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    • 2018
  • Background: Vancomycin-resistant enterococci (VRE) infections have become a major healthcare-associated pathogen problem worldwide. Nosocomial VRE infections could be effectively controlled by screening patients at high risk of harboring VRE and thereby lowering the influx of VRE into healthcare centers. In this study, we evaluated factors associated with VRE colonization in patients transferred to emergency departments, to detect patients at risk for VRE carriage. Methods: This study was conducted in the emergency department of a medical college-affiliated hospital in Korea. Every patient transferred to the emergency department and admitted to the hospital from January to December 2016 was screened for VRE using rectal cultures. In this cross-sectional study, the dependent variable was VRE colonization and the independent variables were demographic and clinical factors of the patients and factors related to the transferring hospital. Patients were divided into two groups, VRE and non-VRE, and previously collected patient data were analyzed. Then we performed logistic regression analyses of characteristics that differed significantly between groups. Results: Out of 650 patients, 106 (16.3%) had positive VRE culture results. Significant variables in the logistic analysis were transfer from geriatric long-term care hospital (adjusted odds ration [aOR]: 8.017; 95% confidence interval [CI]: 1.378-46.651), hospital days (4-7 days; aOR: 7.246; 95% CI: 3.229-16.261), duration of antimicrobial exposure (1-3 days; aOR: 1.976; 95% CI: 1.137-3.436), and age (aOR: 1.025; 95% CI: 1.007-1.043). Conclusion: VRE colonization in patients transferred to the emergency department is associated primarily with factors related to the transferred hospitals rather than demographic and clinical characteristics.

저분체 기반 고유동 콘크리트의 Steel Concrete Panel Mock-up 부재 충전 성능 평가 (Evaluation of Filling Performance of Steel Concrete Panel (SCP) Mock-up Member with Low-binder based High-fluidity Concrete)

  • 박기준;박정준;김성욱
    • 대한토목학회논문집
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    • 제39권4호
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    • pp.477-483
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    • 2019
  • 최근 원자력발전소 및 LNG 저장탱크 등 특수구조물의 공사 기간과 비용 절감을 목적으로 PSC 구조물 대신 프리캐스트 형식의 SCP 모듈의 사용이 증가하고 있다. SCP 모듈 내부는 강재와 콘크리트의 일체 거동을 위해 스터드로 연결되어 있어 고유동 콘크리트의 사용이 요구된다. 고유동 콘크리트는 일반적으로 많은 단위결합재량를 가지기 때문에 수화열 및 수축의 증대, 비경제적인 강도 발현 문제 등이 발생한다. 따라서 본 연구에서는 저분체 기반 고유동 콘크리트 최적 배합을 선정하기 위해 재료적 특성에 따른 고유동 콘크리트의 유동성 및 철근의 간극 통과성능을 검토하고, 펌프카를 활용하여 펌핑 전후에 따른 콘크리트의 물성을 검토하며, 최종적으로 강재와 강재 사이를 콘크리트로 채우는 SCP Mock-up 부재에 대하여 고유동 콘크리트의 충전 성능을 평가하였다.

초국가적 입양과 탈경계적 정체성 -제인 정 트렌카의 『피의 언어』 (Transnational Adoption and Beyond-Borders Identity: Jane Jeong Trenka's The Language of Blood)

  • 김현숙
    • 영어영문학
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    • 제57권1호
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    • pp.147-170
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    • 2011
  • This paper elucidates the characteristics of transnational adoption, estimates the possibility of beyond-borders identity of transnational adoptees, and tries to analyze Jane Jeong Trenka's The Language of Blood in its context. Though it has been regarded as one of the most humanitarian ways of helping orphans and poor children of the world, transnational adoption, a one-way flow of children from poor Asian countries to rich white countries, has been operated under the market logic between countries. Transnational adoptees, who had been abandoned and forced to be taken away from their birth mother, and later, to fulfill the desire of white parents for a perfect family, perform an ideological labor, serving to make the heterogeneous nuclear family complete. Korean transnational adoptees, forced to transcend the borders of nation, culture, and ethnicity, experience racial conflict and alienation in white adoptive family and society. Their diaspora experience of violent dislocation creates frustration and confusion in establishing their identity as a whole being. When they return to Korea to find their birth mother and their true identity, Korean adoptees, however, are faced with other obstructing issues, such as language problem, culture conflict, and maternal nationalism. Finally, Korean transnational adoptees reject Korean nationalism discourse based on blood, and try to redefine themselves as beyond-borders subjectivities with new and fluid identities. Jane Jeong Trenka's The Language of Blood, an autobiographical novel based on her experiences as a transnational adoptee, represents a Korean adopted girl's personal, cultural, and racial conflict within her white adoptive family, and questions the image of benevolent white mother and the myth of multiculturalism. The novel further represents Jane's return to Korea to find out her true identity, and shows Jane's disappointment and alienation in her birth country due to her ignorance of language and culture. Returning to USA again, and trying to be reconciled with her American mother, Jane shows the promise of accepting her new identity capable of transcending the borders, and thus, the possibility of enlarging the category of belonging.

Seismic behavior of liquid storage tanks with 2D and 3D base isolation systems

  • Kilic, Samet;Akbas, Bulent;Shen, Jay;Paolacci, Fabrizio
    • Structural Engineering and Mechanics
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    • 제83권5호
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    • pp.627-644
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    • 2022
  • In past major earthquakes (1994 Northridge, 1995 Kobe, Chi-Chi 1999, Kocaeli 1999), significant damages occurred in the liquid storage tanks. The basic failure patterns were observed to be the buckling of the tank wall and uplift of the anchorage system. The damages in the industrial facilities and nuclear power plants have caused the spread of toxic substances to the environment and significant fires. Seismic isolation can be used in liquid storage tanks to decouple the structure and decrease the structural demand in the superstructure in case of ground shaking. Previous studies on the use of seismic isolation systems on liquid storage tanks show that an isolation system reduces the impulsive response but might slightly increase the convective one. There is still a lack of understanding of the seismic response of seismically isolated liquid storage tanks considering the fluid-structure interaction. In this study, one broad tank, one medium tank, and one slender tank are selected and designed. Two- and three-dimensional elastomeric bearings are used as seismic isolation systems. The seismic performance of the tanks is then investigated through nonlinear dynamic time-history analyses. The effectiveness of each seismic isolation system on tanks' performance was investigated. Isolator tension forces, modal analysis results, hydrodynamic stresses, strains, sloshing heights and base shear forces of the tanks are compared. The results show that the total base shear is lower in 3D-isolators compared to 2D-isolators. Even though the tank wall stresses, and strains are slightly higher in 3D-isolators, they are more efficient to prevent the tension problem.

부착식 텐던의 유효 긴장력 평가를 위한 최적의 매개변수 결정에 관한 연구 (A Study on the Determination of the Optimal Parameter for the Evaluation of the Effective Prestress Force on the Bonded Tendon)

  • 장정범;이홍표;황경민;송영철
    • 대한토목학회논문집
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    • 제30권2A호
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    • pp.161-168
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    • 2010
  • 국내 가동 중 일부 원전의 원자로건물에 부착식 텐던이 설치되어 있고, 부착식 텐던에 대한 유효 긴장력 평가는 이들 원전의 계속운전을 위한 주요 현안으로 부각되고 있다. 따라서, 본 연구에서는 System Identification 기법을 이용한 부착식 텐던의 유효 긴장력 평가를 위하여, SI 기법에 유효한 주요 매개변수의 영향 평가를 수행하고 최적의 매개변수를 도출하였다. 본 연구를 위하여, 원자로건물 벽체의 1/5 축소모형 시험체를 제작하였고, 유효 긴장력과 고유진동수 및 변위와의 상관성을 분석하기 위하여 Impact test, SIMO sine sweep test 및 광섬유센서와 변위계에 의한 휨시험을 수행하였다. 시험결과, 고유진동수와 변위 모두 유효 긴장력과 좋은 상관성을 지니는 것으로 나타나, 이들 매개변수 모두 SI 기법의 입력자료로 활용되어 부착식 텐던의 유효 긴장력 예측이 가능한 것으로 분석되었다.

Research progress on hydrogel-based drug therapy in melanoma immunotherapy

  • Wei He;Yanqin Zhang;Yi Qu;Mengmeng Liu;Guodong Li;Luxiang Pan;Xinyao Xu;Gege Shi;Qiang Hao;Fen Liu;Yuan Gao
    • BMB Reports
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    • 제57권2호
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    • pp.71-78
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    • 2024
  • Melanoma is one of the most aggressive skin tumors, and conventional treatment modalities are not effective in treating advanced melanoma. Although immunotherapy is an effective treatment for melanoma, it has disadvantages, such as a poor response rate and serious systemic immune-related toxic side effects. The main solution to this problem is the use of biological materials such as hydrogels to reduce these side effects and amplify the immune killing effect against tumor cells. Hydrogels have great advantages as local slow-release drug carriers, including the ability to deliver antitumor drugs directly to the tumor site, enhance the local drug concentration in tumor tissue, reduce systemic drug distribution and exhibit good degradability. Despite these advantages, there has been limited research on the application of hydrogels in melanoma treatment. Therefore, this article provides a comprehensive review of the potential application of hydrogels in melanoma immunotherapy. Hydrogels can serve as carriers for sustained drug delivery, enabling the targeted and localized delivery of drugs with minimal systemic side effects. This approach has the potential to improve the efficacy of immunotherapy for melanoma. Thus, the use of hydrogels as drug delivery vehicles for melanoma immunotherapy has great potential and warrants further exploration.

TOUGH-FLAC 기법을 이용한 점열원 주변지반의 복합거동에 대한 벤치마크 수치모사 (Benchmark Numerical Simulation on the Coupled Behavior of the Ground around a Point Heat Source Using the TOUGH-FLAC Approach)

  • 박도현
    • 터널과지하공간
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    • 제34권2호
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    • pp.127-142
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    • 2024
  • 수치해석 기법의 강건성은 다양한 모델링 조건에서 계산 성능이 유지되는 것을 의미하며, 새로운 해석기법 또는 수치코드는 벤치마크 테스트를 통해 강건성이 평가될 필요가 있다. TOUGH-FLAC 모델링 기법은 국내외적으로 이산화탄소 지중저장, 사용후핵연료 지층처분, 지열 개발 등 다양한 분야에 적용되었으며, 실험 계측자료, 다른 수치코드들과의 결과 비교를 통해 모델링 유효성이 분석되었다. 본 연구에서는 해석해를 갖는 열-수리-역학적 복합거동 문제를 토대로 TOUGH-FLAC 기법의 벤치마크 테스트를 수행하였다. 적용된 해석해는 완전히 포화된 지반에 점열원 작용 시 주변매질의 온도, 간극수압, 역학적 거동과 관계되며, 해석해와 수치모사 결과를 비교하여 TOUGH-FLAC 기법의 강건성이 평가되었다. 또한, 열-수리-역학 해석의 연계항, 유체 상변화, 시간증분이 복합거동 계산에 미치는 영향을 조사하였다.