• 대한전기학회논문지:시스템및제어부문D
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• 제51권9호
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• pp.431-437
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• 2002

Low hemolysis is one of the key factors in the production of successful rotary blood pumps. It is, however, difficult to identify the areas where hemolysis occurs. Computational fluid dynamics(CFD) analysis enables the engineer to predict hemolysis on a computer Fluid dynamics in five different axial flow pumps was analyzed 3-dimensionally using CFD software. The impeller was rotated at a speed which supplied a flow of 5L/min at a pressure difference of 100mmHg. Changes in the turbulent kinetic energy along streamlines through the pumps were computed. Reynolds' shear stress( (equation omitted) ) was calculated using the turbulent kinetic energy. Hemolysis was evaluated based on Reynolds'shear stress and its exposure time(t) : dHb/Hb=3.62$\times$10$^{-5}$ $t^{0.785}$$\tau$$^{2.416}$ . Hemolysis of the pumps was measured in vitro using fresh bovine blood to which citrate phosphate dextrose was added to prevent clotting. A pump flow of 5L/min was maintained at a pressure difference of 100mmHg for 3h. The normalized index of hemolysis(NIH) as measured. Reynolds' shear stress was high behind the impellers. The measured NIH and the calculated hemolysis(dHb/Hb) shoed a good correlation; NIH=0.0003(dHb/Hb) (r=0.90, n=6) in the range of NIH between 0.003 and 1.1. CFD analysis can predict the in vitro results of hemolysis as well as the areas where hemolysis occurs.ysis occurs.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 추계학술대회논문집
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• pp.297-302
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• 2007

Vibrating test of vehicle component can be possible in lab-based simulators instead of field testing owing to the development of technology in control algorithm as well as computational process. Currently, Multi-Axial Simulation Table(MAST) is recommended as a vibrating equipment, which excites a target component for 3-directional translation and rotation motion simultaneously and hence, vibrational condition can be fully approximated to that of real road test. But, the vibration-free performance of target component is not guaranteed with MAST system, which is only simulator subjective to the operator. Rather, the reliability of multi-axial vibration test is dependent on the quality of input profile which should cover the required severity of vibrating condition on target component. In this paper, multi-axial vibration testing methodology of vehicle component is presented here, from data acquisition of vehicle accelerations to the obtaining the input profile of MAST using severe data at proving ground. To compare the severity of vibration condition, between real road test and proving ground one, energy principle of equivalent damage is proposed to calculate energy matrices of acceleration data and then, it is determined the optimal combination of special events on proving ground which is equivalent to real road test at the aspects of vibration fatigue using sequential searching optimal algorithm. To explain the vibration methodology clearly, seat and door component of vehicle are selected as a example.

• Nuclear Engineering and Technology
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• 제24권2호
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• pp.111-120
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• 1992

본 논문은 안전정지지진에 대한 spacer grid충격하중의 동적특성을 고찰한 것이다. 안전정지지 진 (SSE： Safe Shutodown Earthquake)을 가진력으로 사용하였고 모델로는 가장 긴 15 row의 핵연료집합체 모델을 사용하였다. 외부에서 제공되는 입력데이타의 불확실성을 보상하기 위하여 흔히 사용되는 10%증가된 입력값과, NRC 권고사항인 입력응답스펙트럼의 이동효과의 영향이 평가되었다. 평가대상으로는 spacer grid의 충격력이 사용되었다. 해석결과로서 입력응답 스펙트럼의 이동효과의 영향은 거의 무시할 수 있으나 증가된 입력값의 영향은 spacer grid의 충격력에 큰 영향을 줌을 알 수 있었다. 따라서 원자로노심의 동적응답을 위해서는 입력응답 스펙트럼을 이동시키면서 해석할 필요가 없음을 확인하였다.

• 한국콘텐츠학회논문지
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• 제4권1호
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• pp.18-23
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• 2004

본 논문에서는 공간주파수 특성과 다중 해상도 특성을 모두 갖는 웨이브릿 변환을 이용하여 각 대역의 특성에 맞는 비주얼 특징을 추출하고 이를 내용기반 영상 검색에 이용하는 새로운 방법을 제시하였다. 웨이브릿 변환된 영상의 최저주파 대역은 원 영상의 근사한 형태로 공간 정보를 충분히 활용할 수 있다. 이를 위해 웨이브릿 계수값과 각 계수간의 공간 정보를 모두 고려한 퍼지 동질성(FH : Fuzzy Homogeneity)를 이용하여 L개의 특징 벡터를 추출하였고, 나머지 고주파 대역의 에너지 값을 이용하여 3개의 특징 벡터를 추출하여 이를 영상 데이터베이스에 저장한다. 질의 시에는 L개의 FH 벡터 중 가장 크기가 큰 10개의 값과 3개의 고주파 대역의 에너지 값을 이용하여 가장 유사한 영상을 검색하였다. 90개의 텍스쳐 영상을 사용해 실험한 결과 좋은 정확성을 보였다.

• Journal of Microbiology and Biotechnology
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• 제19권1호
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• pp.23-36
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• 2009

In the present work, the metabolic network of primary metabolism of the slow-growing myxobacterium Sorangium cellulosum was reconstructed from the annotated genome sequence of the type strain So ce56. During growth on glucose as the carbon source and asparagine as the nitrogen source, So ce56 showed a very low growth rate of $0.23\;d^{-1}$, equivalent to a doubling time of 3 days. Based on a complete stoichiometric and isotopomer model of the central metabolism, $^{13}C$ metabolic flux analysis was carried out for growth with glucose as carbon and asparagine as nitrogen sources. Normalized to the uptake flux for glucose (100%), cells recruited glycolysis (51%) and the pentose phosphate pathway (48%) as major catabolic pathways. The Entner-Doudoroff pathway and glyoxylate shunt were not active. A high flux through the TCA cycle (118%) enabled a strong formation of ATP, but cells revealed a rather low yield for biomass. Inspection of fluxes linked to energy metabolism revealed that S. cellulosum utilized only 10% of the ATP formed for growth, whereas 90% is required for maintenance. This explains the apparent discrepancy between the relatively low biomass yield and the high flux through the energy-delivering TCA cycle. The total flux of NADPH supply (216%) was higher than the demand for anabolism (156%), indicating additional reactions for balancing of NADPH. The cells further exhibited a highly active metabolic cycle, interconverting $C_3$ and $C_4$ metabolites of glycolysis and the TCA cycle. The present work provides the first insight into fluxes of the primary metabolism of myxobacteria, especially for future investigation on the supply of cofactors, building blocks, and energy in myxobacteria, producing natural compounds of biotechnological interest.

• 센서학회지
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• 제23권3호
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• pp.207-210
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• 2014

$TiO_2$ oxide semiconductor is being widely studied in various applications such as photocatalyst and photosensor. Pd/$TiO_2$ gas sensor is mainly used to detect $H_2$, CO and ethanol. This study focus on increasing hydrogen detection ability of Pd/$TiO_2$ in room temperature through Al-doping. Pd/$TiO_2$ was fabricated by the hydrothermal method. Contacting to Aluminum (Al) foil led to Al doping effect in Pd/$TiO_2$ by thermal diffusion and enhanced hydrogen sensing response. $TiO_2$ nanoparticles were sized at ~30 nm of diameter from scanning electron microscope (SEM) and maintained anatase crystal structure after Al doping from X-ray diffraction analysis. Presence of Al in $TiO_2$ was confirmed by X-ray photoelectron spectroscopy at 73 eV. SEM-energy dispersive spectroscopy measurement also confirmed 2 wt% Al in Pd/$TiO_2$ bulk. The gas sensing test was performed with $O_2$, $N_2$ and $H_2$ gas ambient. Pd/Al-doped $TiO_2$ did not response $O_2$ and $N_2$ gas in vacuum except $H_2$. Finally, the normalized resistance ratio ($R_{H2on}/R_{H2off}$) of Pd/Al-doped $TiO_2$ increases about 80% compared to Pd/$TiO_2$.

• 한국전기전자재료학회논문지
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• 제31권7호
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• pp.462-468
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• 2018

The piezoelectric energy harvesting characteristics of a trapezoidal cantilever generator with lead zirconate titanate (PZT) laminate were investigated with various Ag inner electrodes. The piezoelectric mode of operation was a transverse mode by using a planar electrode pattern. The piezoelectric cantilever generator was fabricated using trapezoidal cofired-PZT/Ag laminates by five specimens of 2, 3, 4, 7, and 13 layers of Ag. As the number of Ag electrodes increased, impedance and output voltage at resonant frequency significantly decreased, and capacitance and output current showed an increasing tendency. A maximum output power density of $7.60mW/cm^3$ was realized for the specimen with seven Ag layers in the optimal condition of acceleration (1.2 g) and resistive load ($600{\Omega}$), which corresponds to a normalized power factor of $5.28mW/g^2{\cdot}cm^3$.

• 지구물리와물리탐사
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• 제14권3호
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• pp.214-219
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• 2011

본 논문에서는 시간영역에서 분리된 잔여 파동장을 이용하여 주파수영역 파형역산을 수행하였다. 시간영역 잔여 파동장들을 절대값의 크기에 따라 정렬하여 분류하고, 이를 여러 개의 그룹으로 분리하였다. 분리된 잔여 파동장들은 각 그룹별로 목적함수의 경사 방향을 정규화한 후 평균하기 때문에 통상적인 잔여 파동장에서 작은 크기를 가지는 파동장들을 상대적으로 강조하는 효과가 있고, 이는 파형역산 시 심부구조의 이미지 향상에 도움을 준다. 파형역산은 시간영역에서 분리된 잔여 파동장을 이용하여 주파수영역에서 수행되며, 목적함수의 경사방향은 구조보정에서 많이 쓰이는 역전파 기법을 적용하여 계산된다. 본 연구에서 제안한 알고리듬의 타당성을 확인하기 위하여 SEG/EAGE 암염 모델과 Marmousi 모델을 이용하여 파형역산을 수행하였다. 역산 결과를 통해 제안된 알고리즘이 일반적인 주파수영역 파형역산에 비해 심부구조에 대하여 향상된 결과를 제시함을 확인하였다.

• Environmental Analysis Health and Toxicology
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• 제26권
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• pp.10.1-10.7
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• 2011

Objects: Chironomus riparius, a non-biting midge (Chironomidae, Diptera), is extensively used as a model organism in aquatic ecotoxicological studies, and considering the potential of C. riparius larvae as a bio-monitoring species, little is known about its genome sequences. This study reports the results of an Expressed Sequence Tags (ESTs) sequencing project conducted on C. riparius larvae using 454 pyrosequencing. Method: To gain a better understanding of C. riparius transcriptome, we generated ESTs database of C.ripairus using pyrosequencing method. Results: Sequencing runs, using normalized cDNA collections from fourth instar larvae, yielded 20,020 expressed sequence tags, which were assembled into 8,565 contigs and 11,455 singletons. Sequence analysis was performed by BlastX search against the National Center for Biotechnology Information (NCBI) nucleotide (nr) and uniprot protein database. Based on the gene ontology classifications, 24% (E-value${\leq}1^{-5}$) of the sequences had known gene functions, 24% had unknown functions and 52% of sequences did not match any known sequences in the existing database. Sequence comparison revealed 81% of the genes have homologous genes among other insects belonging to the order Diptera providing tools for comparative genome analyses. Targeted searches using these annotations identified genes associated with essential metabolic pathways, signaling pathways, detoxification of toxic metabolites and stress response genes of ecotoxicological interest. Conclusions: The results obtained from this study would eventually make ecotoxicogenomics possible in a truly environmentally relevant species, such as, C. riparius.

• Structural Engineering and Mechanics
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• 제76권3호
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• pp.279-291
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• 2020

The seismic design of conventional frame structures is meant to enhance plastic deformations at beam ends and prevent yielding in columns. To this end, columns are made stronger than beams. Yet yielding in columns cannot be avoided with the column-to-beam strength ratios (about 1.3) prescribed by seismic codes. Preventing plastic deformations in columns calls for ratios close to 4, which is not feasible for economic reasons. Furthermore, material properties and the rearrangement of geometric shapes inevitably make the distribution of damage among stories uneven. Damage in the i-th story can be characterized as the accumulated plastic strain energy (W_pi) normalized by the product of the story shear force (Q_yi) and drift (δ_yi) at yielding. Past studies showed that the distribution of the plastic strain energy dissipation demand, W_pi/ΣW_pj, can be evaluated from the deviation of Q_yi with respect to an "optimum value" that would make the ratio W_pi/(Q_yiδ_yi) -i.e. the damage- equal in all stories. This paper investigates how the soil type and ductility demand affect the optimum lateral strength distribution. New optimum lateral strength distributions are put forth and compared with others proposed in the literature.