• 한국환경성돌연변이발암원학회지
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• 제19권2호
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• pp.108-111
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• 1999

Correlation between the tumorigenic dose (TD) and the maximum tolerated dose (MTD) was examined to search for the most relevant TD values related to the MTD. Using benzo(a)pyrene (B(a)P) 2-yr bioassay data, correlation coefficients between values of $TD_{1-}$50/ and the MTD were estimated from linearized or non-linearlized dose-response curves. The highest correlation coefficients (0.9966-1.0000) were obtained from T $D_{1-}$10/ in linearized dose-response curves while the highest (0.9966-1.0000) were estimated from $TD _{5-}$10/ in non-linearized dose-response eurves. These data suggest that TDs-lo were more closely related to the MTD than the ,$TD_{5-}$10/ in B(a)P 2-yr bioassay and that in lieu of the $TD_{50}$ they could be efficiently applicable to risk assessment and management.ent.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.174-176
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• 2002

A total of 134 patients with stage 1 of non-small cell lung cancer treated by carbon ion beam of HIMAC NIRS were investigated for control rate and delivered dose. The delivered dose of every patient was converted to biological effective dose (BED) of LQ model using fraction number, dose per fraction and alpha beta ratio which shows the maximum correlation between BED and tumor control. The BED of every patient was classified to establish a BED response curve for control. Assuming fraction numbers, dose response curves were introduced from BED response curve. The total doses to realize several control rates were obtained for the treatment of small fraction number.

• 소음진동
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• 제8권4호
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• pp.715-722
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• 1998

An investigation into the stochastic bifurcation and response statistics of an autoparameteric system under broad-band random excitation is made. The specific system examined is a spring-pendulum system with internal resonance, which is known to be a good model for a variety of engineering systems, including ship motions with nonlinear coupling between pitching and rolling motions. The Fokker-Planck equations is used to genrage a general first-order differential equation in the dynamic moment of response coordinates. By means of the Gaussian and non-Gaussian closure methods the dynamic moment equations for the random responses of the system are reduced to a system of autonomous ordinanary differential equations. In view of equilibrium solutions of this system and their stability we examine the stochastic bifurcation and response statistics. The analytical results are compared with results obtained by Monte Carlo simulation.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(5)
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• pp.99-102
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• 2000

This study analyze of reflection wave to Acoustic stimulation on acupoints and contrast parts for objectification of the meridian substance. In order to verify meridian pathway and channel theory of bio-energy in body. It was analyzed response characteristic of reflection waves after acoustic stimulation by sound wave of 5 specific tones. The response characteristics of reflection are measured by the average current magnitude of meridian. The current variation ratio are Live Meridian(gung) 33.2%, Heart Meridian(sang) 30.7%, Kidney Meridian (gak) 33.1%, Spleen Meridian(chi) 33.9%, Lung Meridian (wo) 30.7% compare with contrast parts (non-acupoint and meridian). Therefore meridian is distinguished to non-meridian and 5 vital meridians have relationship with sound wave of 5 specific tones.

• Steel and Composite Structures
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• 제1권2호
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• pp.245-268
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• 2001

The analysis of steel-concrete composite joints presents some particular aspects that increase their complexity when compared to bare steel joints. In particular, the influence of slab reinforcement and column concrete encasement clearly change the moment-rotation response of the joint. Starting from an energy approach developed in the context of steel joints, an extension to composite joints is presented in this paper that is able to provide closed-form analytical solutions. In addition, the possibility of tri-linear or non-linear component behaviour is also incorporated in the model, enabling adequate treatment of the influence of cracked concrete in tension and the softening response of the column web in compression. This methodology is validated through comparison with experimental tests carried out at the University of Coimbra.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1999년도 추계학술대회 논문집
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• pp.545-548
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• 1999

The electro-optical characteristics of photo-aligned vertical-alignment (VA)-liquid crystal display (LCD) with non-polarized ultraviolet (UV) light irradiation of 45\`on homeotropic polyimide (Pl) surface were investigated. LC alignment on photo-aligned VA-LCD is attributed to photo-depolymerized reaction of the polymer with non-polarized UV light irradiation on PI surface. We had good voltage-transmittance (V-T) characteristics of photo-aligned VA-LCD. The response time of photo-aligned VA-LCD was slower than that of the rubbing-aligned VA-LCD. Finally, we suggest that the slow response time of photo-aligned VA-LCD depends on the LC domain.

• 한국안전학회지
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• 제14권2호
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• pp.42-51
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• 1999

This research deals with the non-linearities associated with impact and sliding for the rocking behavior of rigid block subjected to two dimensional excitation of horizontal and vertical direction. The non-linearities examined of impact between block and base: The transition of two governing rocking equations, the abrupt reduction in kinetic energy associated with impact. In this study, the rocking vibration system of two types are considered for several friction condition. One is the undamped rocking vibration system, disregarding energy dissipation at impact and the other is the damped rocking system, including energy dissipation at impact. The response analysis by non-dimensional rocking equation is carried out for the change of excitation amplitude. The chaos responses were discovered in the wide response region, particularly, in the case of high vertical excitation and their chaos characteristics are examined by Poincare map, power spectra and Lyapunov Exponent. The complex behavior of chaos response, in the phase space, were illustrated by Poincare map. Therefore, Poincare map will be a significant material in order to understand chaos of rocking system.

• 수산경영론집
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• 제40권3호
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• pp.147-167
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• 2009

The objective of this study is to analyze the determinants of at-home laver consumption expenditures using the data from a survey of households implemented in 2009. It happened that non-response ratios of monthly expenditures on dry laver and flavored laver among sampled households are 18.8% and 25.6%. Accordingly, this study tries to analyze the determinants affecting at-home laver consumption expenditures by using type II tobit model, one of sample selection models, to deal with sample selection bias caused from non-response data. Analysis results show the age variable positively affects expenditures on dry laver but negatively contributes to expenditures on flavored laver. In addition, the household size, the household's income, the degree of preference for laver have positive relationships with both expenditures. Household size elasticity and income elasticity of the expenditure on dry laver are estimated as 0.220 and 0.251. In the case of flavored laver, these elasticities are estimated as 0.484 and 0.261. Such analysis results can provide information on division of the at-home laver consumption market into groups with high willingness to expense and implementation of detailed marketing strategies to increase at-home laver consumption. The methodology of this study can be applied to consumer preference analysis on other marine products and other analyses on sample with non-response data in the fishery research.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4801-4804
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• 2013

Purpose: To investigate short-term response rate, quality of life and toxicities of mannan peptide combined with TP regimen in treating patients with non-small cell lung cancer (NSCLC). Patients and Methods: Forty one patients with NSCLC were divided into an experimental group treated with TP regimen combined with mannan peptide (21 patients) and a control group treated with TP alone (20 patients). Results: Response rates were 61.9% (13/21) for the experimental and 60% (12/20) for the control group (p>0.05). Regarding toxicity, white blood cell decreased more frequently in the control group (65%, 13/20) than in the experimental group (33.3%, 7/21) (p<0.05); nausea and vomiting also occurred more frequently in the control group (55%, 11/20 vs 23.8%, 5/21) (p<0.05). In terms of quality of life, this index was improved by 57.1% (12/21) and 25% (5/20) in experimental and control groups, respectively (p<0.05). Conclusions: Response rate of TP after combined with mannan peptide is mildly increased, while this combination alleviates bone marrow suppression as well as nausea and vomiting of TP, and improves quality of life when treating patients with NSCLC. However, this conclusion should be confirmed by randomized clinical trails.

• 동의생리병리학회지
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• 제18권1호
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• pp.172-178
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• 2004

To investigated the effects of Kwibi-tang water extract (KBT) on the non-specific immune response in C57BL/6 mice stressed by immobilization, we evaluated the changes in the contents of serum histamine and corticosterone and the phagocytic activity of macrophages. The level of serum histamine and corticosterone was determined with spectrofluorometer. The cell viability was determined by a MTT assay method. The subpolpulation of lymphocytes was determined by a flow cytometry. The phagocytic activity was determined with luminometer. KBT decreased the serum level of histamine and corticosterone increased by immobilization stress. Also, KBT enhanced the phagocytic activity and decreased the level of nitric oxde in murine peritoneal macrophages decreased by immobilization stress. These results indicate that KBT may be useful for the prevention and treatment of stress via suppression of serum histamine and corticosterone level and enhancement of the non-specific immune response.