• Structural Engineering and Mechanics
• /
• v.61 no.4
• /
• pp.437-440
• /
• 2017

This study investigates the bending of an isotropic thin rectangular plate in finite deformation. Employing hyperelastic material of John's type, a non-classical model which generalizes the famous Kirchhoff's plate equation is obtained. Exact solution for deflection of the plate under sinusoidal loads is obtained. Finally, it is shown that the non-classical plate under consideration can be used as a replacement for Kirchhoff's plate on an elastic foundation.

• Structural Engineering and Mechanics
• /
• v.58 no.5
• /
• pp.905-929
• /
• 2016

This paper assesses efficiency of the continuum method as the idealized system of building structures. A modified Coupled Two-Beam (CTB) model equipped with classical and non-classical damping has been proposed and solved analytically. In this system, complementary (non-classical) damping models composed of bending and shear mechanisms have been defined. A spatial shear damping model which is non-homogeneously distributed has been adopted in the CTB formulation and used to equivalently model passive dampers, viscous and viscoelastic devices, embedded in building systems. The application of continuum-based models for the dynamic analysis of shear wall systems has been further discussed. A reference example has been numerically analyzed to evaluate the efficiency of the presented CTB, and the optimization problems of the shear damping have been finally ascertained using local and global performance indices. The results reveal the superior performance of non-classical damping models against the classical damping. They show that the critical position of the first modal rotation in the CTB is reliable as the optimum placement of the shear damping. The results also prove the good efficiency of such a continuum model, in addition to its simplicity, for the fast estimation of dynamic responses and damping optimization issues in building systems.

• Earthquakes and Structures
• /
• v.13 no.5
• /
• pp.465-471
• /
• 2017

This work derives a generalized time fractional differential equation governing wave propagation in a radially vibrating non-classical cylindrical medium. The cylinder is made of a transversely isotropic hyperelastic John's material which obeys frequency-dependent power law attenuation. Employing the definition of the conformable fractional derivative, the solution of the obtained generalized time fractional wave equation is expressed in terms of product of Bessel functions in spatial and temporal variables; and the resulting wave is characterized by the presence of peakons, the appearance of which fade in density as the order of fractional derivative approaches 2. It is obtained that the transversely isotropic structure of the material of the cylinder increases the wave speed and introduces an additional term in the wave equation. Further, it is observed that the law relating the non-zero components of the Cauchy stress tensor in the cylinder under consideration generalizes the hypothesis of plane strain in classical elasticity theory. This study reinforces the view that fractional derivative is suitable for modeling anomalous wave propagation in media.

• Communications for Statistical Applications and Methods
• /
• v.8 no.3
• /
• pp.787-795
• /
• 2001

In this paper, Bayesian hypothesis testing procedures are proposed under the non-informative prior distributions, which can be thought as the Bayesian counterparts of the classical ones in the sense of using the concept of significance level. The performances of proposed procedures are compared with those of classical procedures through several examples.

• Journal of Fisheries and Marine Sciences Education
• /
• v.29 no.2
• /
• pp.447-452
• /
• 2017

A closely associated set of characteristics was analyzed using both classical and truss dimensions to discriminate sexual dimorphism between spawning season and non spawning season in grass puffer, Takifugu niphobles. In non-spawning season, $1{\times}10/Ls$ of classical dimension was significantly different between male and female (P<0.05). In spawning season, $1{\times}9/Ls$ and $1{\times}10/Ls$ of classical dimension, $3{\times}8/Ls$, $3{\times}9/Ls$, $3{\times}10/Ls$, $4{\times}8/Ls$, $4{\times}9/Ls$ and $8{\times}9/Ls$ of truss dimension and $7{\times}9/HL$ of head part dimension were significantly different between male and female (P<0.05). The results of this study may be useful as basic information of other fish species to compare the change of sexual dimorphism between spawning season and non spawning season.

• Structural Engineering and Mechanics
• /
• v.87 no.1
• /
• pp.57-68
• /
• 2023

Response spectrum method is still an effective approach for the design of buildings with supplemental dampers. In practice, complex complete quadratic combination (CCQC) rule is always used in the response spectrum method to consider the effect of non-classical damping. The conventional CCQC rule is based on exact complex mode vectors. Sometimes the calculated complex mode vectors may be not excited by the external loading and errors in the structural responses always arise due to the mode truncation. Load-dependent Ritz (LDR) vectors are associated with the external loading and LDR vectors not excited can be automatically excluded. Also, contributions of higher modes are implicitly contained in the LDR vectors in terms of static responses. To improve the calculation efficiency and accuracy, LDR vectors are introduced in the CCQC rule in the present study. Firstly, the generation procedure of LDR vectors suitable for non-classical damping system is presented. Compared to the conventional LDR vectors, the LDR vectors herein are complex-valued and named as complex LDR (CLDR) vectors. Based on the CLDR vectors, the CCQC rule is then rederived and an improved response spectrum method is developed. Finally, the effectiveness of the proposed method in this paper is verified through three typical non-classical damping buildings. Numerical results show that the CLDR vector is superior to the complex mode with the same number in the calculation. Since the generation of CLDR vectors requires less computational cost and storage space, the method proposed in this paper offers an attractive alternative, especially for structures with a large number of degrees of freedom.

• IMMUNE NETWORK
• /
• v.21 no.4
• /
• pp.31.1-31.16
• /
• 2021

Gastric cancer (GC) is the fourth most common cause of cancer-related death globally. The classification of advanced GC (AGC) according to molecular features has recently led to effective personalized cancer therapy for some patients. Specifically, AGC patients whose tumor cells express high levels of human epidermal growth factor receptor 2 (HER2) can now benefit from trastuzumab, a humanized monoclonal Ab that targets HER2. However, patients with HER2^negative AGC receive limited clinical benefit from this treatment. To identify potential immune therapeutic targets in HER2^negative AGC, we obtained 40 fresh AGC specimens immediately after surgical resections and subjected the CD45⁺ immune cells in the tumor microenvironment to multi-channel/multi-panel flow cytometry analysis. Here, we report that HER2 negativity associated with reduced overall survival (OS) and greater tumor infiltration with neutrophils and non-classical monocytes. The potential pro-tumoral activities of these cell types were confirmed by the fact that high expression of neutrophil or non-classical monocyte signature genes in the gastrointestinal tumors in The Cancer Genome Atlas, Genotype-Tissue Expression and Gene Expression Omnibus databases associated with worse OS on Kaplan-Meir plots relative to tumors with low expression of these signature genes. Moreover, advanced stage disease in the AGCs of our patients associated with greater tumor frequencies of neutrophils and non-classical monocytes than early stage disease. Thus, our study suggests that these 2 myeloid populations may serve as novel therapeutic targets for HER2^negative AGC.

• Journal of applied mathematics & informatics
• /
• v.29 no.1_2
• /
• pp.75-85
• /
• 2011

In this paper, using the energy estimates and the bootstrap arguments, the global existence of classical solutions for a prey-predator model with non-monotonic functional response and cross-diffusion where the prey and predator both have linear density restriction is proved when the space dimension n < 10.

• Advances in nano research
• /
• v.13 no.5
• /
• pp.453-463
• /
• 2022

This paper aims to investigate the vibration analysis of functionally graded porous (FGP) beams using State-space approach with several classical and non-classical boundary conditions. The materials properties of the porous FG beams are considered to have even and uneven distributions profiles along the thickness direction. The equation of motion for FGP beams with various boundary conditions is obtained through Hamilton's principle. State-space approach is used to obtain the governing equation of porous FG beam. The comparison of the results of this study with those in the literature validates the present analysis. The effects of span-to-depth ratio (L/h), of distribution shape of porosity and others parameters on the dynamic behavior of the beams are described. The results show that the boundary conditions, the geometry of the beams and the distribution shape of porosity affect the fundamental frequencies of the beams.

• Bulletin of the Korean Mathematical Society
• /
• v.55 no.5
• /
• pp.1599-1619
• /
• 2018

In this paper we study the initial value problem of the non-relativistic Vlasov-Darwin system with generalized variables (VDG). We first prove local existence and uniqueness of a nonnegative classical solution to VDG in three space variables, and establish the blow-up criterion. Then we show that it converges to the well-known Vlasov-Poisson system when the light velocity c tends to infinity in a pointwise sense.