• Title/Summary/Keyword: non-Human

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Molecular Cloning And analysis of Korean Insulin Gene (한국인 인슈린 유전자의 클로닝 및 분석)

  • 김형민;한상수;고건일;손동환;전창덕;정헌택;김재백
    • YAKHAK HOEJI
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    • v.37 no.5
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    • pp.504-510
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    • 1993
  • Human insulin gene is consisted of the polymorphic region with the repeating units, the regulatory sequence, the structural gene including the intervening sequence, and 3'-flanking region. The polymerase chain reaction, which amplifies the target DNA between two specific primers, has been performed for the amplification of human insulin gene and simple one-step cloning of it into Escherichia coli. Out of 1727 nuceotides compared, only 4 sites were variable: 5'-regulatory region(G2101$\rightarrow$AGG); IVS I(T2401$\rightarrow$A); Exon II(C2411 deletion); IVS II(A2740 dejection). The variations at the G2101 and T2401 were the same as those found in one American allele. The other two variations were observed only in the specific Korean allele. And, the enzyme digestion patterns among normal, insulin dependent diabetes mellitus, and non-insulin dependent diabetes mellitus were the same. On the other hand, PCR method showed the possibility of the quickaccess for the polymorphic region in terms of the restriction fragment length of polymorphism.

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Nutritional Support for Acute Diarrhea in Children: Focused on Age-appropriate Diet Therapy after Rehydration (영유아 급성 설사의 영양 공급: 탈수 치료 후 연령별 식이요법을 중심으로)

  • Chu, Mi Ae;Choe, Byung-Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.12 no.sup1
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    • pp.53-61
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    • 2009
  • The mainstay in the management of mild to moderately dehydrated children is fast rehydration by using hypotonic ORS (oral rehydration solution) and complete resumption of normal diet, including lactose-containing formula after 4 hours rehydration. Since the majority of young children with uncomplicated acute diarrhea will tolerate large amounts of undiluted non-human milk, withholding food and milk from children during diarrhea is not recommended anymore, regarding time to resolution and diarrhea control. In addition, routine dilution of milk and routine use of lactose-free formula are not necessary after fast ORS therapy. Breastfed infants and children fed with solid foods may safely continue receiving their usual diets during diarrhea instead of gradual reintroduction of feeding. However, young infants or children with severe diarrhea or malnutrition should be carefully treated under supervision if fed with lactose containing, non-human milk exclusively.

Consumers' Overconfidence Biases in Relation to Social Exclusion

  • HAN, Woong-Hee
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.7
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    • pp.303-308
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    • 2020
  • Unlike previous studies of overconfidence bias that have been looking for causes of overconfidence bias in human cognitive error or in the desire to view oneself positively, this study presents the cognitive narrowing resulting from the social exclusion experience as the condition of overconfidence bias and investigates the mechanism of cognitive narrowing to overcome the negative emotions from social exclusion, and how overconfidence bias occur due to cognitive narrowing. Current study was performed with 94 undergraduate students. Participants were randomly assigned to social exclusion experience group or non-experience group. We analyzed how the degree of bias of overconfidence differs according to the social exclusion experience. The degree of overconfidence bias of the social exclusion experience group was higher than that of the non-experience group, and the difference was statistically significant. This study extends the concepts of escaping theory and cognitive narrowing to human cognitive bias and confirmed that social exclusion experience increased cognitive narrowing and overconfidence bias. Implications of this research and future research directions were discussed.

A study on the effect of employment flexibility on the business performance in the computer programming, system consultancy and related service industry (고용유연성이 기업성과에 미치는 영향에 관한 연구 : 컴퓨터 프로그래밍, 시스템 통합 및 관리업을 중심으로)

  • Cho, Jae-Jeong;Rhew, Sung-Yul
    • Journal of Korean Society for Quality Management
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    • v.38 no.3
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    • pp.425-438
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    • 2010
  • This study investigates what effects employment flexibility have on the business performance in the computer programming, system consultancy and related services. An analysis of the effects of employment flexibility on outcomes of human resource management revealed that companies which had a higher proportion of temporary agency workers and adjusted employment more frequently had higher turnover rates. The study also showed that the higher the proportion of non-regular workers, outsourcing and the easier it was to adjust working hours, the higher the absence rate. Meanwhile, companies that made employment adjustments more often showed higher defect rates and lower customer satisfaction. It was also found that in companies with a higher proportion of outsourcing and higher possibility of employment adjustments, workers were less interested in new technologies.

Correlation between Phylogeny and Zn-Resistance in Methylobacterium Species Isolated from Non-Polluted Soil Environments

  • Kim, Hong-Ik;Kazunori Nakamura;Hiroshi Oyaizu
    • Proceedings of the Korean Society for Applied Microbiology Conference
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    • 2000.10a
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    • pp.118-124
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    • 2000
  • Zn-resistant Methylosobacterium strains were isolated from several non-polluted soil samples collected in all over Japan. Zn-resistant Methylosobacterium strains were predominantly detected in all soil samples and they were also characterized as a UV-tolerant bacteria. The MIC test revealed that the isolates have high zinc resistance in comparison with that of reference Methylosobacterium strains obtained from culture collections. The 16S rDNA-based phylogenetic analysis showed that all strains were divided into two clusters designated as cluster A and cluster B in the present study. All isolates were distributed only in the cluster A. The phylogenetic clustering also well coincided with the differences in the pattern of carbon source utilization.

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Ban-mal and Hierarchical Structures : Professor Chung′s Theory Critically Examined (반말과 계층 구조 -정대현 교수의 반말 이론에 대한 비판적 검토-)

  • 선우환
    • Lingua Humanitatis
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    • v.5
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    • pp.93-106
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    • 2003
  • Professor Daihyun Chung has recently presented an intriguing view of Ban-mal(non-honorific expressions) in Korean. He criticizes uses of Ban-mal, on the grounds that they presuppose the existence of hierarchical structures in human beings. Professor Chung also advocates ″a relational theory of Ban-mal″ according to which ascriptions of 'n-mal' should be relativized to the speaker-hearer relationship. He employs this view in showing that uses of Ban-mal indeed presuppose the existence of hierarchical structures in human beings I claim that Professor Chung has not shown the credibility of his relational theory of Ban-mal, and that this very view leads to an unintended and undesirable consequence. Moreover, 1 show that even if we assume that this view is true for the sake of an argument, he is not able to show that uses of Ban-mal indeed presuppose the existence of hierarchical structures. All he can show is rather that uses of 'Ban-mal'(a meta-linguistic expression) presuppose the existence of hierarchical structures. Finally, 1 conclude that what really presupposes the existence of hierarchical structures is the asymmetrical uses of Ban-mal and honorific expressions.

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Email Classification using Dynamic Category Hierarchy and Non-negative Matrix Factorization (비음수 행렬 분해와 동적 분류체계를 사용한 이메일 분류)

  • Park, Sun;An, Dong Un
    • Annual Conference on Human and Language Technology
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    • 2009.10a
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    • pp.35-39
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    • 2009
  • 이메일의 사용증가로 수신 메일을 효율적이면서 정확하게 분류할 필요성이 점차 증가하고 있다. 현재의 이메일 분류는 베이지안, 규칙 기반 등을 이용하여 스팸 메일을 필터링하기 위한 이원 분류가 주를 이루고 있다. 클러스터링을 이용한 다원 분류 방법은 분류의 정확도가 떨어지는 단점이 있다. 본 논문에서는 비음수 행렬 분해(NMF, Non-negative Matrix Factrazation)를 기반으로 한 자동 분류 주제 생성 방법과 동적 분류 체계(DCH, Dynamic Category Hierachy) 방법을 결합한 새로운 이메일 분류 방법을 제안한다. 이 방법은 수신되는 이메일을 자동으로 분류하여 대량의 메일을 효율적으로 관리할 수 있으며, 분류 결과 사용자의 요구사항을 만족하지 못하면 메일을 동적으로 재분류 하여 분류 정확률을 높일 수 있다.

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Non-Saponin Fraction from Panax ginseng C.A. Meyer Inhibits Platelet Aggregation (혈소판 응집반응을 억제시키는 Panax ginsing C.A. Meyer의 비사포닌 분획)

  • Park, Kyeong-Mee;Rhee, Man-Hee;Park, Hwa-Jin
    • Journal of Ginseng Research
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    • v.17 no.3
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    • pp.246-249
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    • 1993
  • Hexane, Hexane/diethylether and chloroform fractions from Panax ginseng C.A. Meyer stroungly inhibitied human platelet aggregation induced by a high dose of thrombin (2$\mu$/ml). Chloroform fraction more strongly inhibited the platelet aggregation than the other two fraction among them. There were fatty acid ester and phosphate ester instead of polyacethylene compounds in the chloroform fraction.

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A Study on the Effectiveness of Programming Education for Developing Creativity and Personality of Non-Majors Using DEVS Methodology (DEVS 방법론을 이용한 비전공자의 창의·인성 함양을 위한 프로그래밍 교육의 효과도 분석 연구)

  • Han, Youngshin
    • Journal of Korea Multimedia Society
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    • v.22 no.9
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    • pp.1080-1090
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    • 2019
  • The digital informational era of the 21st century requires the fostering of human resource in the field of software with creativity and personality. This paper deals with the educating method in programming course for non-majors which fosters creativity for problem solving ability and personality using cooperative interaction to build communication ability. We also seek to build a model through DEVS methodology for creative problem solving and analyze the effects of programming education for the cultivation of creativity and personality. Our proposed model is expected to be used as a guide to establish creativity and personality for human resource cultivation in programming education.

Differential Protein and Gene Expression after Adenovirus-Mediated p16 Gene Transfer in Human Non-Small Cell Lung Cancer Cells

  • Park, Mi-Sun;Kang , Ho-Il;Jee, Seung-Wan;Lim, Si-Nae;Pyo, Jae-Hee;Eom , Mi-Ok;Ryeom , Tai-Kyung;Kim, Ok-Hee
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.291.2-291.2
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    • 2002
  • For the safety evaluation of adenovirus-mediated gene therapy. we have investigated gene and protein expression after transduction of adenoviral vector (Ad5CMV-p16) which contains tumor suppressor gene. p161NK4$\alpha$ in human non-small cell lung cancer (A549) cells. We compared the differential gene expression level in the A549 cells treated with Ad5CMV (null type) and Ad5CMV-p16 virus. respectively. by using cDNA membrane chip and oligonucleotide chip. (omitted)

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